𝕏

Task 55427551

Name HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_143_0
Workunit 26320236
Created 30 Jun 2024, 10:06:11 UTC
Sent 30 Jun 2024, 11:33:56 UTC
Report deadline 3 Jul 2024, 21:09:56 UTC
Received 3 Jul 2024, 8:27:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234361
Run time 2 hours 33 min 32 sec
CPU time 2 hours 10 min 43 sec
Validate state Valid
Credit 58.99
Device peak FLOPS 4.84 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.02 MB
Peak swap size 3.99 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_143.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_143_0_r287464930_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_143_0_r287464930_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.965760
     * GNaL_b in INaL: 0.007484
     * Gto_b in Ito: 0.088936
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030861
     * GKs_b in IKs: 0.001994
     * GK1_b in IK1: 0.181888
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 69.281788
     * GKb_b in IKb: 0.003668
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050674
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_143.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_143_0_r287464930_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_143_0_r287464930_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.965760
     * GNaL_b in INaL: 0.007484
     * Gto_b in Ito: 0.088936
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030861
     * GKs_b in IKs: 0.001994
     * GK1_b in IK1: 0.181888
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 69.281788
     * GKb_b in IKb: 0.003668
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050674
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 15252672
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.004757 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 28017667, states[0] = 21.991676, states[40]= 0.011257
Saving checkpoint... 
Iteration: 41879046, states[0] = -95.050641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55812991, states[0] = -95.013528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69610078, states[0] = -22.031928, states[40]= 0.000893
Saving checkpoint... 
Iteration: 83282459, states[0] = -94.983908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96964470, states[0] = -95.052890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111195742, states[0] = -94.865209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124340573, states[0] = -95.016751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138537332, states[0] = 17.846214, states[40]= 0.005041
Saving checkpoint... 
Iteration: 152283390, states[0] = -94.979573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166414298, states[0] = -95.040252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179854365, states[0] = -95.021396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193939418, states[0] = -95.045139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207743548, states[0] = -94.937793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221496889, states[0] = -95.053102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235237710, states[0] = -94.930137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248902360, states[0] = -95.036826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262563310, states[0] = 8.661714, states[40]= 0.004725
Saving checkpoint... 
Iteration: 276308794, states[0] = -94.997434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290129385, states[0] = -38.762967, states[40]= 0.000174
Saving checkpoint... 
Iteration: 304028376, states[0] = 20.368590, states[40]= 0.005818
Saving checkpoint... 
Iteration: 317664184, states[0] = -82.924133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331370354, states[0] = -95.027039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344937542, states[0] = -95.044473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359052172, states[0] = 12.856758, states[40]= 0.004767
Saving checkpoint... 
Iteration: 372250416, states[0] = -94.945872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386276332, states[0] = -94.972547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400090468, states[0] = -5.174302, states[40]= 0.003274
Saving checkpoint... 
Iteration: 414253325, states[0] = -94.949202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427598030, states[0] = -10.987250, states[40]= 0.002080
Saving checkpoint... 
Iteration: 441855526, states[0] = -95.021354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455592542, states[0] = -6.661396, states[40]= 0.002967
Saving checkpoint... 
Iteration: 469753461, states[0] = -94.949316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483151603, states[0] = -62.775820, states[40]= 0.000004
Saving checkpoint... 
Iteration: 497392472, states[0] = -95.033919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511156604, states[0] = -69.606905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524743044, states[0] = -94.936782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538444652, states[0] = -95.045609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552606560, states[0] = -18.374578, states[40]= 0.001097
Saving checkpoint... 
Iteration: 566450413, states[0] = -95.046564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580139036, states[0] = -48.432906, states[40]= 0.000041
Saving checkpoint... 
Iteration: 593907483, states[0] = -95.037829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608012298, states[0] = 22.791153, states[40]= 0.029587
Saving checkpoint... 
Iteration: 621704738, states[0] = -94.878758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635392337, states[0] = -95.033780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649043292, states[0] = 15.941590, states[40]= 0.004850
Saving checkpoint... 
Iteration: 663104253, states[0] = -16.344872, states[40]= 0.001280
Saving checkpoint... 
Iteration: 676776849, states[0] = -94.972797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690473690, states[0] = -95.049916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704067709, states[0] = 6.861887, states[40]= 0.004674
Saving checkpoint... 
Iteration: 718141614, states[0] = -51.205751, states[40]= 0.000026
Saving checkpoint... 
Iteration: 731842341, states[0] = -95.015438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745389281, states[0] = -95.032817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759075110, states[0] = 3.562770, states[40]= 0.004497
Saving checkpoint... 
Iteration: 773064308, states[0] = 8.262674, states[40]= 0.004716
Saving checkpoint... 
Iteration: 786460745, states[0] = -95.048026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800171254, states[0] = -92.747329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813796046, states[0] = -94.988257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827720920, states[0] = -94.905412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840964943, states[0] = -95.048601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854997848, states[0] = -95.052649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868600826, states[0] = -13.358289, states[40]= 0.001670
Saving checkpoint... 
Iteration: 882393499, states[0] = -95.033929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895625664, states[0] = -35.306486, states[40]= 0.000280
Saving checkpoint... 
Iteration: 909875098, states[0] = -95.028244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923793754, states[0] = -94.986476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937744285, states[0] = -94.938039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951037379, states[0] = 17.849703, states[40]= 0.005039
Saving checkpoint... 
Iteration: 965142871, states[0] = -52.583474, states[40]= 0.000021
Saving checkpoint... 
Iteration: 979124228, states[0] = -33.999415, states[40]= 0.000331
Saving checkpoint... 
Iteration: 993237623, states[0] = -94.929403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006841758, states[0] = -95.014968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020878663, states[0] = -95.029340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034876412, states[0] = -95.028591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049012035, states[0] = 22.815750, states[40]= 0.031390
Saving checkpoint... 
Iteration: 1062592743, states[0] = -6.809843, states[40]= 0.002936
Saving checkpoint... 
Iteration: 1076524568, states[0] = 21.221017, states[40]= 0.006605
Saving checkpoint... 
Iteration: 1090400417, states[0] = -95.035665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104445405, states[0] = -95.045328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117950351, states[0] = -95.046153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131848584, states[0] = -95.017940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145869076, states[0] = -95.025991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159756259, states[0] = -94.951948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173553034, states[0] = 12.546672, states[40]= 0.004765
Saving checkpoint... 
Iteration: 1187294160, states[0] = -94.986588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201451201, states[0] = -95.046231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215302343, states[0] = -94.992437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229078160, states[0] = 2.074423, states[40]= 0.004373
Saving checkpoint... 
Iteration: 1242865815, states[0] = -95.024742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256995916, states[0] = -95.052152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270769598, states[0] = -94.965638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284576502, states[0] = 2.894612, states[40]= 0.004445
Saving checkpoint... 
Iteration: 1298430527, states[0] = -95.042429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312632534, states[0] = -41.790730, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1326321705, states[0] = -95.004449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340127593, states[0] = -37.083310, states[40]= 0.000220
Saving checkpoint... 
Iteration: 1353949934, states[0] = -95.045912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368190945, states[0] = -94.851198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382044078, states[0] = 15.677954, states[40]= 0.004836
Saving checkpoint... 
Iteration: 1395916283, states[0] = -95.039330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409784487, states[0] = -94.978824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423949539, states[0] = -95.045796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437764744, states[0] = -94.960723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451513050, states[0] = 22.727106, states[40]= 0.025113
Saving checkpoint... 
Iteration: 1465461390, states[0] = -95.047628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479514384, states[0] = 22.621263, states[40]= 0.019189
Saving checkpoint... 
Iteration: 1493443150, states[0] = -95.044651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507159693, states[0] = -95.227618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521038557, states[0] = 15.314808, states[40]= 0.005913
Saving checkpoint... 
Iteration: 1535083579, states[0] = -95.267825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548874503, states[0] = -95.268312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562625106, states[0] = -95.223278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576408341, states[0] = -95.202097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590609876, states[0] = 23.826640, states[40]= 0.052780
Saving checkpoint... 
Iteration: 1604363742, states[0] = -95.270409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618125238, states[0] = -95.230362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631950549, states[0] = -95.259602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646196331, states[0] = -26.872997, states[40]= 0.000662
Saving checkpoint... 
Iteration: 1660009212, states[0] = -40.215097, states[40]= 0.000144
Saving checkpoint... 
Iteration: 1673781117, states[0] = -11.497418, states[40]= 0.002279
Saving checkpoint... 
Iteration: 1687640575, states[0] = -85.235533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701850171, states[0] = -95.259931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715729527, states[0] = 18.497440, states[40]= 0.006683
Saving checkpoint... 
Iteration: 1729396697, states[0] = -95.187596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742747072, states[0] = 10.908965, states[40]= 0.005600
Saving checkpoint... 
Iteration: 1756253716, states[0] = 7.622956, states[40]= 0.005428
Saving checkpoint... 
Iteration: 1769491270, states[0] = -21.765914, states[40]= 0.000938
Saving checkpoint... 
Iteration: 1783225617, states[0] = 19.875069, states[40]= 0.007419
Saving checkpoint... 
Iteration: 1796659185, states[0] = -95.268370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810747085, states[0] = -94.977022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824480141, states[0] = -95.077319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838512819, states[0] = 22.593626, states[40]= 0.026206
Saving checkpoint... 
Iteration: 1852084086, states[0] = -1.590171, states[40]= 0.003935
Saving checkpoint... 
Iteration: 1866006144, states[0] = 25.285409, states[40]= 0.127502
Saving checkpoint... 
Iteration: 1879830730, states[0] = -95.014200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893651188, states[0] = -62.635532, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1907191279, states[0] = -94.854056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921182477, states[0] = -94.797029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935077476, states[0] = 2.383769, states[40]= 0.004402
Saving checkpoint... 
Iteration: 1949005816, states[0] = 25.803229, states[40]= 0.135562
Saving checkpoint... 
Iteration: 1962543213, states[0] = 15.960205, states[40]= 0.004852
Saving checkpoint... 
Iteration: 1976513336, states[0] = 22.701614, states[40]= 0.023645
Saving checkpoint... 
Iteration: 1990409899, states[0] = -95.037527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004344898, states[0] = -95.015734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017713349, states[0] = -94.892413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031716422, states[0] = -94.897389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045626387, states[0] = -35.971516, states[40]= 0.000256
Saving checkpoint... 
Iteration: 2059661987, states[0] = -78.704550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073092074, states[0] = -6.318355, states[40]= 0.003039
Saving checkpoint... 
Iteration: 2087174566, states[0] = -94.129439, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.927777
 - CaMKt in component CaMK (millimolar): 0.007366
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.657328
 - nass in component intracellular_ions (millimolar): 6.657387
 - ki in component intracellular_ions (millimolar): 145.316323
 - kss in component intracellular_ions (millimolar): 145.316304
 - cansr in component intracellular_ions (millimolar): 1.325789
 - cajsr in component intracellular_ions (millimolar): 1.286465
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003609
 - hf in component INa (dimensionless): 0.880450
 - hs in component INa (dimensionless): 0.880446
 - j in component INa (dimensionless): 0.880420
 - hsp in component INa (dimensionless): 0.726680
 - jp in component INa (dimensionless): 0.880403
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.708703
 - hLp in component INaL (dimensionless): 0.447272
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.612025
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.685236
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.927460
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999858
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001647
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335851
 - xs1 in component IKs (dimensionless): 0.258538
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997330
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:27:23 (7800): called boinc_finish(0)

</stderr_txt>
]]>


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