𝕏

Task 55427368

Name HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_232_1
Workunit 26320144
Created 30 Jun 2024, 10:06:06 UTC
Sent 30 Jun 2024, 11:32:20 UTC
Report deadline 3 Jul 2024, 21:08:20 UTC
Received 3 Jul 2024, 15:11:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224565
Run time 1 hours 17 min 10 sec
CPU time 1 hours 14 min 20 sec
Validate state Valid
Credit 61.78
Device peak FLOPS 6.30 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.37 MB
Peak swap size 3.82 MB
Peak disk usage 0.25 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_232.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_232_1_r1458136400_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630120543010578_ORdGradInc_k_25-Pueyo_APDR-conf_232_1_r1458136400_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 112.483012
     * GNaL_b in INaL: 0.005509
     * Gto_b in Ito: 0.091858
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033385
     * GKs_b in IKs: 0.001924
     * GK1_b in IK1: 0.161191
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 67.811401
     * GKb_b in IKb: 0.003712
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020781
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14420261, states[0] = -94.976372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27983423, states[0] = -94.966370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42575849, states[0] = -2.283750, states[40]= 0.003949
Saving checkpoint... 
Iteration: 57024098, states[0] = 19.341748, states[40]= 0.007021
Saving checkpoint... 
Iteration: 71588523, states[0] = -11.944114, states[40]= 0.001985
Saving checkpoint... 
Iteration: 85649230, states[0] = -77.958235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99491986, states[0] = -94.938686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114029036, states[0] = 18.135378, states[40]= 0.005975
Saving checkpoint... 
Iteration: 127695112, states[0] = -94.714128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142226164, states[0] = -94.775059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156198703, states[0] = -94.721095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169911968, states[0] = -94.919822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183482464, states[0] = -94.934028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197871666, states[0] = -94.905913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211877909, states[0] = -94.908301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225537305, states[0] = 15.510419, states[40]= 0.005252
Saving checkpoint... 
Iteration: 239636623, states[0] = -60.379776, states[40]= 0.000005
Saving checkpoint... 
Iteration: 253180487, states[0] = -94.674535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267676443, states[0] = -94.653329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280570518, states[0] = 1.451186, states[40]= 0.004447
Saving checkpoint... 
Iteration: 294728142, states[0] = -94.777291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307378082, states[0] = -94.908174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321883317, states[0] = -94.910116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335313990, states[0] = -94.874286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348669063, states[0] = -94.491307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363238982, states[0] = -94.794616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377614773, states[0] = -36.993470, states[40]= 0.000200
Saving checkpoint... 
Iteration: 391903587, states[0] = -94.916783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405534615, states[0] = 16.425878, states[40]= 0.005416
Saving checkpoint... 
Iteration: 420006897, states[0] = 23.983700, states[40]= 0.113283
Saving checkpoint... 
Iteration: 434275058, states[0] = -94.840406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448773122, states[0] = -94.838341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462683198, states[0] = -94.683288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476026988, states[0] = 18.732678, states[40]= 0.006317
Saving checkpoint... 
Iteration: 489612575, states[0] = -34.818905, states[40]= 0.000267
Saving checkpoint... 
Iteration: 503708128, states[0] = -94.739932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517711412, states[0] = -94.746484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530587564, states[0] = -10.667722, states[40]= 0.002227
Saving checkpoint... 
Iteration: 545192001, states[0] = -94.705204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559795644, states[0] = -94.859826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572684846, states[0] = -94.687817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586639807, states[0] = -64.140630, states[40]= 0.000003
Saving checkpoint... 
Iteration: 601231797, states[0] = -94.783124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615687582, states[0] = -94.694753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629534304, states[0] = 16.528729, states[40]= 0.005438
Saving checkpoint... 
Iteration: 642785866, states[0] = -94.851002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656689874, states[0] = -94.700201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670454801, states[0] = -94.928831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683693312, states[0] = -94.708080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697315141, states[0] = -94.874828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711123018, states[0] = -45.429550, states[40]= 0.000058
Saving checkpoint... 
Iteration: 725652540, states[0] = -82.919893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739750609, states[0] = -94.810994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752669277, states[0] = -94.501722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766612973, states[0] = -35.210941, states[40]= 0.000253
Saving checkpoint... 
Iteration: 781250896, states[0] = -94.811350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795164186, states[0] = -93.930697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809491435, states[0] = -94.934499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823594667, states[0] = -17.385897, states[40]= 0.001194
Saving checkpoint... 
Iteration: 837758698, states[0] = -94.821398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851610306, states[0] = -32.592075, states[40]= 0.000350
Saving checkpoint... 
Iteration: 864538265, states[0] = 15.175402, states[40]= 0.005205
Saving checkpoint... 
Iteration: 878637018, states[0] = -60.831662, states[40]= 0.000005
Saving checkpoint... 
Iteration: 892084526, states[0] = -8.019086, states[40]= 0.002784
Saving checkpoint... 
Iteration: 905444524, states[0] = -94.926647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920005901, states[0] = 25.382977, states[40]= 0.138955
Saving checkpoint... 
Iteration: 933656736, states[0] = -89.245154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947881633, states[0] = -94.909031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961475370, states[0] = -94.932103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976074116, states[0] = -0.599510, states[40]= 0.004197
Saving checkpoint... 
Iteration: 990494751, states[0] = -94.934795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005126097, states[0] = -48.714038, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1019455466, states[0] = -94.928698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033987426, states[0] = -94.933796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048506450, states[0] = 24.531342, states[40]= 0.124717
Saving checkpoint... 
Iteration: 1061889275, states[0] = -94.911676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076384847, states[0] = -94.910108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090425012, states[0] = -94.922115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104530204, states[0] = 17.818846, states[40]= 0.005825
Saving checkpoint... 
Iteration: 1118553330, states[0] = 9.420615, states[40]= 0.004877
Saving checkpoint... 
Iteration: 1132383830, states[0] = -94.909700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146948096, states[0] = -94.927191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161012474, states[0] = 21.563819, states[40]= 0.030088
Saving checkpoint... 
Iteration: 1174852721, states[0] = -94.896554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187897013, states[0] = -94.914154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202003715, states[0] = 32.267762, states[40]= 0.166569
Saving checkpoint... 
Iteration: 1216096105, states[0] = -18.782649, states[40]= 0.001064
Saving checkpoint... 
Iteration: 1229701066, states[0] = -94.724696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243522045, states[0] = 19.934052, states[40]= 0.007893
Saving checkpoint... 
Iteration: 1257584149, states[0] = -7.704530, states[40]= 0.002852
Saving checkpoint... 
Iteration: 1272011584, states[0] = 21.724846, states[40]= 0.036833
Saving checkpoint... 
Iteration: 1286208829, states[0] = -94.740767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299872974, states[0] = -94.905433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314474060, states[0] = -94.931641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327713502, states[0] = -94.749966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342249658, states[0] = -94.809259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356498480, states[0] = -94.934992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370467599, states[0] = -94.930564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383433423, states[0] = -94.923893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397262940, states[0] = -94.826141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411705636, states[0] = -94.734161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425427325, states[0] = -94.922432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439086157, states[0] = -9.416420, states[40]= 0.002485
Saving checkpoint... 
Iteration: 1453278374, states[0] = -94.843078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467289636, states[0] = -94.853875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481060175, states[0] = 6.502868, states[40]= 0.004790
Saving checkpoint... 
Iteration: 1494590285, states[0] = -13.180791, states[40]= 0.001763
Saving checkpoint... 
Iteration: 1507363546, states[0] = -94.964811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521785153, states[0] = -95.032759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535055077, states[0] = -95.158520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548913644, states[0] = 21.897795, states[40]= 0.025209
Saving checkpoint... 
Iteration: 1562795537, states[0] = -35.917670, states[40]= 0.000231
Saving checkpoint... 
Iteration: 1576144543, states[0] = -95.165386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590508135, states[0] = -95.113826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604234207, states[0] = -89.655033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618132425, states[0] = -95.154892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631467859, states[0] = -6.028909, states[40]= 0.003618
Saving checkpoint... 
Iteration: 1645378446, states[0] = -95.054150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658677416, states[0] = -95.205059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673123774, states[0] = 18.789029, states[40]= 0.008347
Saving checkpoint... 
Iteration: 1686838677, states[0] = -95.164733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699858554, states[0] = 1.261643, states[40]= 0.004999
Saving checkpoint... 
Iteration: 1713556746, states[0] = -95.185881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727632466, states[0] = -95.156560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741813081, states[0] = 21.925939, states[40]= 0.027989
Saving checkpoint... 
Iteration: 1755301254, states[0] = 49.914705, states[40]= 0.038228
Saving checkpoint... 
Iteration: 1769588410, states[0] = -95.078234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1782985336, states[0] = -25.011888, states[40]= 0.000708
Saving checkpoint... 
Iteration: 1796935500, states[0] = -95.160649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810707683, states[0] = -94.785489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825120152, states[0] = -44.702026, states[40]= 0.000066
Saving checkpoint... 
Iteration: 1838841139, states[0] = -94.913822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852928538, states[0] = -94.937983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866485177, states[0] = -94.943254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879701350, states[0] = -94.731990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894055935, states[0] = 8.253636, states[40]= 0.004849
Saving checkpoint... 
Iteration: 1907891513, states[0] = -94.914812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921832618, states[0] = -94.887168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935569331, states[0] = 2.053823, states[40]= 0.004507
Saving checkpoint... 
Iteration: 1949085574, states[0] = -8.950736, states[40]= 0.002584
Saving checkpoint... 
Iteration: 1963302753, states[0] = -94.865174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977382996, states[0] = -94.909101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990578965, states[0] = -3.748847, states[40]= 0.003675
Saving checkpoint... 
Iteration: 2005038067, states[0] = 15.243116, states[40]= 0.005214
Saving checkpoint... 
Iteration: 2018874665, states[0] = -94.905626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033191140, states[0] = -94.702130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046736618, states[0] = -94.789719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060002653, states[0] = 39.200653, states[40]= 0.132848
Saving checkpoint... 
Iteration: 2073136769, states[0] = -60.543668, states[40]= 0.000005
Saving checkpoint... 
Iteration: 2086776476, states[0] = -94.840612, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.810450
 - CaMKt in component CaMK (millimolar): 0.007231
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.719230
 - nass in component intracellular_ions (millimolar): 6.719291
 - ki in component intracellular_ions (millimolar): 145.252663
 - kss in component intracellular_ions (millimolar): 145.252643
 - cansr in component intracellular_ions (millimolar): 1.333744
 - cajsr in component intracellular_ions (millimolar): 1.295906
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003652
 - hf in component INa (dimensionless): 0.878406
 - hs in component INa (dimensionless): 0.878401
 - j in component INa (dimensionless): 0.878370
 - hsp in component INa (dimensionless): 0.722830
 - jp in component INa (dimensionless): 0.878350
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708332
 - hLp in component INaL (dimensionless): 0.451806
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.624660
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.700361
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939148
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999898
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001685
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.325408
 - xs1 in component IKs (dimensionless): 0.234188
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997361
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:11:28 (18067): called boinc_finish(0)

</stderr_txt>
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