𝕏

Task 55426810

Name HuVeMOp_20240627004113829118_ORdGradInc_k_24-Pueyo_APDR-conf_377_2
Workunit 26070107
Created 30 Jun 2024, 10:05:10 UTC
Sent 30 Jun 2024, 11:27:22 UTC
Report deadline 3 Jul 2024, 21:03:22 UTC
Received 30 Jun 2024, 15:06:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239941
Run time 2 hours 57 min 11 sec
CPU time 1 hours 42 min 41 sec
Validate state Valid
Credit 62.04
Device peak FLOPS 5.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.02 MB
Peak swap size 391.76 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627004113829118_ORdGradInc_k_24-Pueyo_APDR-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627004113829118_ORdGradInc_k_24-Pueyo_APDR-conf_377_2_r612058806_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627004113829118_ORdGradInc_k_24-Pueyo_APDR-conf_377_2_r612058806_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.607526
     * GNaL_b in INaL: 0.005930
     * Gto_b in Ito: 0.073570
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032856
     * GKs_b in IKs: 0.001776
     * GK1_b in IK1: 0.155782
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 63.647487
     * GKb_b in IKb: 0.004029
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035511
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 20066374, states[0] = 2.394535, states[40]= 0.004662
Saving checkpoint... 
Iteration: 42390900, states[0] = -95.015642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64519336, states[0] = 21.649364, states[40]= 0.011018
Saving checkpoint... 
Iteration: 82138341, states[0] = -64.526546, states[40]= 0.000002
Saving checkpoint... 
Iteration: 105010081, states[0] = 24.326797, states[40]= 0.051934
Saving checkpoint... 
Iteration: 126028700, states[0] = 18.946363, states[40]= 0.006748
Saving checkpoint... 
Iteration: 148018433, states[0] = 21.961484, states[40]= 0.012117
Saving checkpoint... 
Iteration: 170218836, states[0] = -94.854868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192527552, states[0] = 19.340585, states[40]= 0.006980
Saving checkpoint... 
Iteration: 214752958, states[0] = -94.904607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236528244, states[0] = 19.116422, states[40]= 0.006837
Saving checkpoint... 
Iteration: 255846035, states[0] = -94.978781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278018557, states[0] = 21.938078, states[40]= 0.011961
Saving checkpoint... 
Iteration: 299949088, states[0] = -95.010794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322299998, states[0] = -94.950429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343910444, states[0] = -95.002151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365785269, states[0] = -94.938271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387912441, states[0] = -95.002648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409847524, states[0] = -94.979365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429353674, states[0] = -94.982220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451156046, states[0] = -90.020096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474072036, states[0] = 0.165517, states[40]= 0.004397
Saving checkpoint... 
Iteration: 496261873, states[0] = -94.914791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517645442, states[0] = -73.630440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539520134, states[0] = 21.529470, states[40]= 0.010291
Saving checkpoint... 
Iteration: 561263473, states[0] = -94.916537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580344509, states[0] = -94.977797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600219974, states[0] = -94.856050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622249485, states[0] = -94.899865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644329262, states[0] = -94.969645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666330106, states[0] = -94.970113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688766557, states[0] = -94.919821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711548927, states[0] = 11.189036, states[40]= 0.005220
Saving checkpoint... 
Iteration: 733575340, states[0] = -1.850078, states[40]= 0.004090
Saving checkpoint... 
Iteration: 755660502, states[0] = -93.256443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775780802, states[0] = -94.933981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795974613, states[0] = -95.014691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818390789, states[0] = -94.996150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840635777, states[0] = -60.923840, states[40]= 0.000004
Saving checkpoint... 
Iteration: 863098750, states[0] = -22.172279, states[40]= 0.000841
Saving checkpoint... 
Iteration: 885644670, states[0] = -72.479789, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627004113829118_ORdGradInc_k_24-Pueyo_APDR-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627004113829118_ORdGradInc_k_24-Pueyo_APDR-conf_377_2_r612058806_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627004113829118_ORdGradInc_k_24-Pueyo_APDR-conf_377_2_r612058806_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.607526
     * GNaL_b in INaL: 0.005930
     * Gto_b in Ito: 0.073570
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032856
     * GKs_b in IKs: 0.001776
     * GK1_b in IK1: 0.155782
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 63.647487
     * GKb_b in IKb: 0.004029
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035511
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 885644670
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -72.479789 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 910091244, states[0] = -14.868955, states[40]= 0.001522
Saving checkpoint... 
Iteration: 932439530, states[0] = -95.008563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954992081, states[0] = -95.016940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977686406, states[0] = -94.789659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000196643, states[0] = -94.811766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020326165, states[0] = -94.967625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043040178, states[0] = 14.751113, states[40]= 0.005552
Saving checkpoint... 
Iteration: 1065399799, states[0] = -94.998760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087877114, states[0] = -94.991344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110429430, states[0] = -95.006317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131009064, states[0] = 24.873194, states[40]= 0.065314
Saving checkpoint... 
Iteration: 1153805603, states[0] = -94.954102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175899613, states[0] = -94.998641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195574203, states[0] = -1.134159, states[40]= 0.004207
Saving checkpoint... 
Iteration: 1218199288, states[0] = -94.817036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240608071, states[0] = -31.287950, states[40]= 0.000398
Saving checkpoint... 
Iteration: 1263042466, states[0] = 13.839656, states[40]= 0.005438
Saving checkpoint... 
Iteration: 1285759693, states[0] = -94.911850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307993269, states[0] = -95.016881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330133595, states[0] = -58.375819, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1350245316, states[0] = -94.894003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373048765, states[0] = 11.256970, states[40]= 0.005225
Saving checkpoint... 
Iteration: 1393998544, states[0] = -95.017457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416522819, states[0] = 20.790315, states[40]= 0.008528
Saving checkpoint... 
Iteration: 1439393526, states[0] = -94.996650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462396053, states[0] = -94.997412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484578581, states[0] = -4.037965, states[40]= 0.003684
Saving checkpoint... 
Iteration: 1507035383, states[0] = -87.148818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529129032, states[0] = 17.667479, states[40]= 0.007726
Saving checkpoint... 
Iteration: 1549249347, states[0] = 7.152260, states[40]= 0.005741
Saving checkpoint... 
Iteration: 1569140052, states[0] = -93.947870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590989779, states[0] = -29.975905, states[40]= 0.000454
Saving checkpoint... 
Iteration: 1613019015, states[0] = -95.229704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635383831, states[0] = -23.486820, states[40]= 0.000798
Saving checkpoint... 
Iteration: 1657841488, states[0] = 11.184379, states[40]= 0.006220
Saving checkpoint... 
Iteration: 1679497450, states[0] = -38.877477, states[40]= 0.000152
Saving checkpoint... 
Iteration: 1701675783, states[0] = -14.499214, states[40]= 0.001768
Saving checkpoint... 
Iteration: 1724465793, states[0] = -4.455242, states[40]= 0.004027
Saving checkpoint... 
Iteration: 1744130751, states[0] = -95.248562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1766672121, states[0] = -95.292528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788822881, states[0] = -95.237687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810922181, states[0] = -95.055901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833309823, states[0] = -94.985553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855742538, states[0] = -94.905491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877741568, states[0] = -94.896921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900135222, states[0] = -60.614054, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1919568788, states[0] = 1.916032, states[40]= 0.004612
Saving checkpoint... 
Iteration: 1941607560, states[0] = -30.865301, states[40]= 0.000417
Saving checkpoint... 
Iteration: 1963479090, states[0] = -95.015333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985172706, states[0] = -94.721202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006836814, states[0] = -94.973187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028519979, states[0] = 21.569610, states[40]= 0.010428
Saving checkpoint... 
Iteration: 2050362982, states[0] = -94.985319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072320556, states[0] = -94.963593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090933870, states[0] = -95.006682, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.893054
 - CaMKt in component CaMK (millimolar): 0.006791
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.746968
 - nass in component intracellular_ions (millimolar): 6.747028
 - ki in component intracellular_ions (millimolar): 145.231774
 - kss in component intracellular_ions (millimolar): 145.231754
 - cansr in component intracellular_ions (millimolar): 1.309210
 - cajsr in component intracellular_ions (millimolar): 1.272048
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003622
 - hf in component INa (dimensionless): 0.879848
 - hs in component INa (dimensionless): 0.879844
 - j in component INa (dimensionless): 0.879815
 - hsp in component INa (dimensionless): 0.725543
 - jp in component INa (dimensionless): 0.879796
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710811
 - hLp in component INaL (dimensionless): 0.455128
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.626337
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.702035
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937742
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999894
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001604
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332514
 - xs1 in component IKs (dimensionless): 0.233251
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997339
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:00:12 (6081): called boinc_finish(0)

</stderr_txt>
]]>