𝕏

Task 55426797

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-Pieske_333-conf_656_3
Workunit 25854847
Created 30 Jun 2024, 9:57:57 UTC
Sent 30 Jun 2024, 11:25:26 UTC
Report deadline 3 Jul 2024, 11:25:26 UTC
Received 3 Jul 2024, 5:34:20 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min 23 sec
CPU time 37 min 30 sec
Validate state Valid
Credit 45.47
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.50 MB
Peak swap size 391.75 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Pieske_333-conf_656.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Pieske_333-conf_656_3_r1202609130_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Pieske_333-conf_656_3_r1202609130_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 111.272335
     * GNaL_b in INaL: 0.007541
     * Gto_b in Ito: 0.070974
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033613
     * GKs_b in IKs: 0.001790
     * GK1_b in IK1: 0.149371
     * Gncx_b in INaCa_i: 0.000950
     * Pnak_b in INaK: 65.186431
     * GKb_b in IKb: 0.003872
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040430
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9495706, states[0] = -87.937104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19482130, states[0] = -87.898214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29810532, states[0] = -87.890920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39850488, states[0] = 18.700612, states[40]= 0.011663
Saving checkpoint... 
Iteration: 49550606, states[0] = -10.280256, states[40]= 0.003263
Saving checkpoint... 
Iteration: 59183137, states[0] = 17.949615, states[40]= 0.010881
Saving checkpoint... 
Iteration: 68687856, states[0] = 14.565498, states[40]= 0.009055
Saving checkpoint... 
Iteration: 77660464, states[0] = 43.037984, states[40]= 0.053888
Saving checkpoint... 
Iteration: 88325844, states[0] = 43.419919, states[40]= 0.043189
Saving checkpoint... 
Iteration: 98628927, states[0] = -87.887147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109121057, states[0] = -87.858792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118282079, states[0] = -87.833924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126794728, states[0] = -87.896714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134998733, states[0] = 23.075769, states[40]= 0.031323
Saving checkpoint... 
Iteration: 143953557, states[0] = -87.872352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154570114, states[0] = -54.393677, states[40]= 0.000020
Saving checkpoint... 
Iteration: 165200414, states[0] = -3.858946, states[40]= 0.005220
Saving checkpoint... 
Iteration: 174625572, states[0] = -87.906351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185383430, states[0] = -29.782360, states[40]= 0.000534
Saving checkpoint... 
Iteration: 194511569, states[0] = 12.572905, states[40]= 0.008528
Saving checkpoint... 
Iteration: 204110143, states[0] = -87.853930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214944597, states[0] = -87.864517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224422129, states[0] = -87.105831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234048883, states[0] = -35.029767, states[40]= 0.000302
Saving checkpoint... 
Iteration: 243627452, states[0] = -87.936972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252383742, states[0] = -39.839036, states[40]= 0.000165
Saving checkpoint... 
Iteration: 262679567, states[0] = 6.659300, states[40]= 0.007466
Saving checkpoint... 
Iteration: 270495829, states[0] = 17.589158, states[40]= 0.010613
Saving checkpoint... 
Iteration: 281366958, states[0] = -19.760917, states[40]= 0.001321
Saving checkpoint... 
Iteration: 291943509, states[0] = -87.892464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302848637, states[0] = 1.082378, states[40]= 0.006462
Saving checkpoint... 
Iteration: 312752697, states[0] = -87.682897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322960533, states[0] = -87.960754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332217237, states[0] = -51.748259, states[40]= 0.000030
Saving checkpoint... 
Iteration: 341067869, states[0] = -80.751273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350442452, states[0] = -87.910530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359255243, states[0] = -87.815340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366487465, states[0] = 16.880692, states[40]= 0.010111
Saving checkpoint... 
Iteration: 375404183, states[0] = -86.277486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386081103, states[0] = -87.750998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395740504, states[0] = -87.425017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405454321, states[0] = -87.966479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415309529, states[0] = 20.343875, states[40]= 0.014862
Saving checkpoint... 
Iteration: 423693087, states[0] = -30.011928, states[40]= 0.000522
Saving checkpoint... 
Iteration: 432624763, states[0] = 43.398046, states[40]= 0.044509
Saving checkpoint... 
Iteration: 442370905, states[0] = -48.803862, states[40]= 0.000046
Saving checkpoint... 
Iteration: 452384459, states[0] = -71.690277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 463047815, states[0] = -67.885556, states[40]= 0.000002
Saving checkpoint... 
Iteration: 472418541, states[0] = -87.862850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480786273, states[0] = 42.656110, states[40]= 0.025721
Saving checkpoint... 
Iteration: 489818267, states[0] = 10.583962, states[40]= 0.008123
Saving checkpoint... 
Iteration: 497744589, states[0] = -87.837987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505814601, states[0] = 12.013083, states[40]= 0.008405
Saving checkpoint... 
Iteration: 516058905, states[0] = -86.949792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527263503, states[0] = -87.929211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537065159, states[0] = -87.731308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548089495, states[0] = -87.910854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557566874, states[0] = -87.796590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567834492, states[0] = -14.150112, states[40]= 0.002282
Saving checkpoint... 
Iteration: 576995594, states[0] = -7.637632, states[40]= 0.004076
Saving checkpoint... 
Iteration: 585671234, states[0] = -21.781090, states[40]= 0.001099
Saving checkpoint... 
Iteration: 595786234, states[0] = 22.942615, states[40]= 0.029984
Saving checkpoint... 
Iteration: 606968879, states[0] = 13.518821, states[40]= 0.008762
Saving checkpoint... 
Iteration: 617022283, states[0] = -52.040146, states[40]= 0.000029
Saving checkpoint... 
Iteration: 624393128, states[0] = -87.791722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634615860, states[0] = 22.853334, states[40]= 0.029096
Saving checkpoint... 
Iteration: 643621782, states[0] = 19.440057, states[40]= 0.012845
Saving checkpoint... 
Iteration: 654564092, states[0] = -87.848393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665557454, states[0] = -87.810677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675594724, states[0] = -87.968393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685039795, states[0] = -86.241022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694909195, states[0] = -87.914448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703046684, states[0] = -87.670039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712765111, states[0] = 36.273538, states[40]= 0.103454
Saving checkpoint... 
Iteration: 721112136, states[0] = 20.416167, states[40]= 0.015066
Saving checkpoint... 
Iteration: 731960939, states[0] = 10.426791, states[40]= 0.008094
Saving checkpoint... 
Iteration: 743413605, states[0] = -87.945410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753743262, states[0] = -87.936941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764506429, states[0] = -50.393272, states[40]= 0.000037
Saving checkpoint... 
Iteration: 774139069, states[0] = -3.352075, states[40]= 0.005365
Saving checkpoint... 
Iteration: 783971953, states[0] = -3.970340, states[40]= 0.005189
Saving checkpoint... 
Iteration: 792532767, states[0] = -87.243249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802258445, states[0] = 29.340435, states[40]= 0.105932
Saving checkpoint... 
Iteration: 812624071, states[0] = 7.050616, states[40]= 0.007529
Saving checkpoint... 
Iteration: 823248203, states[0] = -87.972538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833688193, states[0] = -84.067708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844188740, states[0] = -85.289202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850847558, states[0] = -76.687621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 860264492, states[0] = 20.614627, states[40]= 0.015668
Saving checkpoint... 
Iteration: 872103207, states[0] = 17.088335, states[40]= 0.010245
Saving checkpoint... 
Iteration: 884189456, states[0] = -87.100481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895216548, states[0] = -87.891853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904783895, states[0] = 5.133925, states[40]= 0.007216
Saving checkpoint... 
Iteration: 914228589, states[0] = -87.941197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921441003, states[0] = 11.119542, states[40]= 0.008224
Saving checkpoint... 
Iteration: 930538807, states[0] = -87.859585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940050934, states[0] = -87.912634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951038412, states[0] = -87.867196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960998495, states[0] = -68.689650, states[40]= 0.000002
Saving checkpoint... 
Iteration: 968348670, states[0] = -87.266516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976009691, states[0] = -85.760725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986273045, states[0] = 7.305234, states[40]= 0.007569
Saving checkpoint... 
Iteration: 997229696, states[0] = -87.969265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007816030, states[0] = -51.286000, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1016385381, states[0] = -87.942172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026862827, states[0] = -87.860988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037072329, states[0] = 24.726786, states[40]= 0.053493
Saving checkpoint... 
Iteration: 1046987400, states[0] = -64.565514, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1056183225, states[0] = -87.790499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067192237, states[0] = -87.861532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077024857, states[0] = -87.862821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086152875, states[0] = -69.083586, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1094630663, states[0] = -36.716989, states[40]= 0.000246
Saving checkpoint... 
Iteration: 1105224686, states[0] = 41.829581, states[40]= 0.068748
Saving checkpoint... 
Iteration: 1116165939, states[0] = -87.036434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126650264, states[0] = -71.532586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1137065860, states[0] = 22.727303, states[40]= 0.027896
Saving checkpoint... 
Iteration: 1147779389, states[0] = -18.406013, states[40]= 0.001503
Saving checkpoint... 
Iteration: 1156508974, states[0] = -87.815619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166847842, states[0] = -87.856221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175399670, states[0] = 20.600518, states[40]= 0.015621
Saving checkpoint... 
Iteration: 1182746696, states[0] = 12.151143, states[40]= 0.008434
Saving checkpoint... 
Iteration: 1192076369, states[0] = 13.946022, states[40]= 0.008879
Saving checkpoint... 
Iteration: 1200916820, states[0] = 8.394485, states[40]= 0.007746
Saving checkpoint... 
Iteration: 1211720592, states[0] = 25.424938, states[40]= 0.064140
Saving checkpoint... 
Iteration: 1222119884, states[0] = -39.537575, states[40]= 0.000171
Saving checkpoint... 
Iteration: 1233283390, states[0] = -36.615471, states[40]= 0.000249
Saving checkpoint... 
Iteration: 1242836762, states[0] = -87.837374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253463557, states[0] = -59.512153, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1262091649, states[0] = -4.977674, states[40]= 0.004891
Saving checkpoint... 
Iteration: 1272211618, states[0] = 29.009034, states[40]= 0.103953
Saving checkpoint... 
Iteration: 1281588333, states[0] = -3.369372, states[40]= 0.005361
Saving checkpoint... 
Iteration: 1292369183, states[0] = -87.975469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302738642, states[0] = 9.379834, states[40]= 0.007910
Saving checkpoint... 
Iteration: 1313931805, states[0] = -21.888793, states[40]= 0.001088
Saving checkpoint... 
Iteration: 1324238100, states[0] = 8.183162, states[40]= 0.007712
Saving checkpoint... 
Iteration: 1333666390, states[0] = -87.864949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341928075, states[0] = -20.520982, states[40]= 0.001232
Saving checkpoint... 
Iteration: 1351419397, states[0] = -9.322294, states[40]= 0.003563
Saving checkpoint... 
Iteration: 1361702180, states[0] = 29.996127, states[40]= 0.109096
Saving checkpoint... 
Iteration: 1372289098, states[0] = -66.033686, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1383859391, states[0] = -87.973571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393671397, states[0] = -87.909120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403357293, states[0] = -87.973120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414515247, states[0] = -87.951132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423805292, states[0] = -87.512350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433888573, states[0] = 11.930660, states[40]= 0.008387
Saving checkpoint... 
Iteration: 1444416747, states[0] = -18.930072, states[40]= 0.001429
Saving checkpoint... 
Iteration: 1452959503, states[0] = -83.985123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462930486, states[0] = -41.482995, states[40]= 0.000132
Saving checkpoint... 
Iteration: 1472380795, states[0] = 14.501351, states[40]= 0.009049
Saving checkpoint... 
Iteration: 1483225344, states[0] = 5.712428, states[40]= 0.007312
Saving checkpoint... 
Iteration: 1491652548, states[0] = -87.873329, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.854973
 - CaMKt in component CaMK (millimolar): 0.040189
 - cass in component intracellular_ions (millimolar): 0.000115
 - nai in component intracellular_ions (millimolar): 7.134474
 - nass in component intracellular_ions (millimolar): 7.134620
 - ki in component intracellular_ions (millimolar): 144.790986
 - kss in component intracellular_ions (millimolar): 144.790952
 - cansr in component intracellular_ions (millimolar): 1.600173
 - cajsr in component intracellular_ions (millimolar): 1.180573
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.007361
 - hf in component INa (dimensionless): 0.697322
 - hs in component INa (dimensionless): 0.697084
 - j in component INa (dimensionless): 0.687564
 - hsp in component INa (dimensionless): 0.453040
 - jp in component INa (dimensionless): 0.662736
 - mL in component INaL (dimensionless): 0.000189
 - hL in component INaL (dimensionless): 0.302313
 - hLp in component INaL (dimensionless): 0.141800
 - a in component Ito (dimensionless): 0.001003
 - iF in component Ito (dimensionless): 0.999552
 - iS in component Ito (dimensionless): 0.180025
 - ap in component Ito (dimensionless): 0.000511
 - iFp in component Ito (dimensionless): 0.999552
 - iSp in component Ito (dimensionless): 0.218022
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.803229
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966227
 - jca in component ICaL (dimensionless): 0.950092
 - ffp in component ICaL (dimensionless): 0.999891
 - fcafp in component ICaL (dimensionless): 0.999993
 - nca in component ICaL (dimensionless): 0.009335
 - xrf in component IKr (dimensionless): 0.027519
 - xrs in component IKr (dimensionless): 0.800040
 - xs1 in component IKs (dimensionless): 0.455074
 - xs2 in component IKs (dimensionless): 0.001034
 - xk1 in component IK1 (dimensionless): 0.996771
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:34:10 (20685): called boinc_finish(0)

</stderr_txt>
]]>


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