𝕏

Task 55426775

Name HuVeMOp_20240627004042410665_ORdGradInc_k_24-Pueyo_APDR-conf_72_2
Workunit 26069557
Created 30 Jun 2024, 9:55:16 UTC
Sent 30 Jun 2024, 11:26:03 UTC
Report deadline 3 Jul 2024, 21:02:03 UTC
Received 3 Jul 2024, 8:51:40 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227612
Run time 1 hours 21 min 21 sec
CPU time 1 hours 19 min 44 sec
Validate state Valid
Credit 62.95
Device peak FLOPS 8.57 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627004042410665_ORdGradInc_k_24-Pueyo_APDR-conf_72.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627004042410665_ORdGradInc_k_24-Pueyo_APDR-conf_72_2_r1996837123_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627004042410665_ORdGradInc_k_24-Pueyo_APDR-conf_72_2_r1996837123_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 96.113810
     * GNaL_b in INaL: 0.008029
     * Gto_b in Ito: 0.091595
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032960
     * GKs_b in IKs: 0.001841
     * GK1_b in IK1: 0.165828
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 61.630371
     * GKb_b in IKb: 0.003864
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035424
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9177466, states[0] = -94.625704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17807899, states[0] = -94.929880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26433816, states[0] = -94.978097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39840928, states[0] = -94.941394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49068593, states[0] = 5.549759, states[40]= 0.004672
Saving checkpoint... 
Iteration: 62004523, states[0] = 28.172887, states[40]= 0.176553
Saving checkpoint... 
Iteration: 74105489, states[0] = -19.743395, states[40]= 0.001021
Saving checkpoint... 
Iteration: 85235944, states[0] = -94.836807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97968929, states[0] = -94.977535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110198511, states[0] = -94.767118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123803857, states[0] = -94.912835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135714327, states[0] = -94.798547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149149607, states[0] = -63.867588, states[40]= 0.000003
Saving checkpoint... 
Iteration: 162165478, states[0] = -88.410320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174512856, states[0] = 22.230857, states[40]= 0.025685
Saving checkpoint... 
Iteration: 187073601, states[0] = 3.291740, states[40]= 0.004539
Saving checkpoint... 
Iteration: 198577033, states[0] = 1.564187, states[40]= 0.004390
Saving checkpoint... 
Iteration: 211702066, states[0] = -94.774006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224331599, states[0] = -94.931396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232449670, states[0] = -94.973297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236967731, states[0] = -94.976488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246607809, states[0] = -21.726561, states[40]= 0.000918
Saving checkpoint... 
Iteration: 259462125, states[0] = -94.975528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272828064, states[0] = -94.929202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285459501, states[0] = -94.975048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298758530, states[0] = -94.867154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311619822, states[0] = -32.460784, states[40]= 0.000410
Saving checkpoint... 
Iteration: 323697408, states[0] = -94.764018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337186336, states[0] = -94.729565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349821204, states[0] = -94.924765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362156230, states[0] = -72.988494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 375326971, states[0] = -94.928436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388341078, states[0] = -94.936618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401245278, states[0] = -94.849381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413959903, states[0] = -94.975008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425677811, states[0] = -94.548287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438203910, states[0] = -94.777569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446802534, states[0] = -94.911160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460534848, states[0] = 18.051843, states[40]= 0.005071
Saving checkpoint... 
Iteration: 473869763, states[0] = -94.950102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485888664, states[0] = -94.957186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498886760, states[0] = -94.956517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510894093, states[0] = -94.958977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523815888, states[0] = -94.921022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536891512, states[0] = -94.958105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549525098, states[0] = 20.581040, states[40]= 0.006196
Saving checkpoint... 
Iteration: 563072114, states[0] = 4.006005, states[40]= 0.004588
Saving checkpoint... 
Iteration: 575667603, states[0] = -90.926885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587875154, states[0] = -94.952162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599988071, states[0] = -94.979171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611668574, states[0] = -91.790410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624517119, states[0] = 21.860803, states[40]= 0.011717
Saving checkpoint... 
Iteration: 636407841, states[0] = -94.963066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648555092, states[0] = 11.113556, states[40]= 0.004769
Saving checkpoint... 
Iteration: 657965815, states[0] = -94.975809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671083368, states[0] = -2.014446, states[40]= 0.003920
Saving checkpoint... 
Iteration: 684656237, states[0] = -72.998674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 697595991, states[0] = -11.303634, states[40]= 0.002060
Saving checkpoint... 
Iteration: 710410215, states[0] = -94.963675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719358488, states[0] = -94.945012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731313859, states[0] = -94.919424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744308079, states[0] = -94.915195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752845758, states[0] = -94.938789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765624749, states[0] = -37.003171, states[40]= 0.000230
Saving checkpoint... 
Iteration: 779248752, states[0] = -94.853931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788463595, states[0] = -94.975329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801387254, states[0] = -94.956435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814223455, states[0] = -94.814369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827439422, states[0] = -94.970711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840308642, states[0] = -94.915536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853070075, states[0] = 4.952624, states[40]= 0.004643
Saving checkpoint... 
Iteration: 865661528, states[0] = -81.917218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874799325, states[0] = -94.908210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885812873, states[0] = -94.918592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899467615, states[0] = -94.975902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913017583, states[0] = 21.810052, states[40]= 0.010993
Saving checkpoint... 
Iteration: 925376661, states[0] = -94.952462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938662548, states[0] = -83.712292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951042477, states[0] = 15.615625, states[40]= 0.004824
Saving checkpoint... 
Iteration: 963795012, states[0] = -94.904517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977550776, states[0] = 12.706853, states[40]= 0.004769
Saving checkpoint... 
Iteration: 990104383, states[0] = -18.677089, states[40]= 0.001092
Saving checkpoint... 
Iteration: 1003025970, states[0] = 20.392207, states[40]= 0.006009
Saving checkpoint... 
Iteration: 1011820281, states[0] = -94.923598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025421410, states[0] = -94.966380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038753433, states[0] = -94.860008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050140541, states[0] = -53.261562, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1062918250, states[0] = -94.965542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075633257, states[0] = -45.395550, states[40]= 0.000068
Saving checkpoint... 
Iteration: 1087805258, states[0] = -94.912757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096707599, states[0] = -94.784432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110532875, states[0] = 18.628131, states[40]= 0.005191
Saving checkpoint... 
Iteration: 1122424214, states[0] = -94.966995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136136872, states[0] = -49.232678, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1148654001, states[0] = -69.686856, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1161640004, states[0] = -52.664478, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1174923439, states[0] = -94.966760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187134953, states[0] = -47.177065, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1200693969, states[0] = -94.755419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213141288, states[0] = -54.095972, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1225866572, states[0] = -94.948143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239577332, states[0] = 1.409032, states[40]= 0.004374
Saving checkpoint... 
Iteration: 1251609740, states[0] = -23.439947, states[40]= 0.000846
Saving checkpoint... 
Iteration: 1264705483, states[0] = -94.780058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278371746, states[0] = -94.950234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291496701, states[0] = -94.979698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305310674, states[0] = -94.916649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314898909, states[0] = -94.959836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328445971, states[0] = -94.971639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341513363, states[0] = 22.191051, states[40]= 0.022990
Saving checkpoint... 
Iteration: 1354565283, states[0] = 7.057608, states[40]= 0.004725
Saving checkpoint... 
Iteration: 1368028612, states[0] = 19.769847, states[40]= 0.005591
Saving checkpoint... 
Iteration: 1380819525, states[0] = -94.922785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394065126, states[0] = 7.124074, states[40]= 0.004727
Saving checkpoint... 
Iteration: 1407017389, states[0] = 21.831749, states[40]= 0.011284
Saving checkpoint... 
Iteration: 1415375660, states[0] = -94.951666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423875770, states[0] = -94.951701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437177311, states[0] = -94.516196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450548231, states[0] = 13.620460, states[40]= 0.004773
Saving checkpoint... 
Iteration: 1459219396, states[0] = -94.806575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471758219, states[0] = -94.865777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484826189, states[0] = -94.927017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497720230, states[0] = -94.808053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510933004, states[0] = -69.866359, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1524401489, states[0] = -32.863899, states[40]= 0.000378
Saving checkpoint... 
Iteration: 1533037085, states[0] = 15.118889, states[40]= 0.005943
Saving checkpoint... 
Iteration: 1546407672, states[0] = -95.132714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560269486, states[0] = -95.220379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572818639, states[0] = -95.161579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586310714, states[0] = -95.150894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599322241, states[0] = 20.340314, states[40]= 0.008301
Saving checkpoint... 
Iteration: 1612399242, states[0] = -95.132154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625246458, states[0] = -93.682133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638069768, states[0] = -3.319359, states[40]= 0.004209
Saving checkpoint... 
Iteration: 1651560790, states[0] = 2.751297, states[40]= 0.005136
Saving checkpoint... 
Iteration: 1664453399, states[0] = 6.901091, states[40]= 0.005438
Saving checkpoint... 
Iteration: 1677139409, states[0] = -86.528763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690454745, states[0] = -95.216919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703287332, states[0] = -95.108726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716837709, states[0] = -95.196821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1729687186, states[0] = -95.108434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742681135, states[0] = -95.241604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751704311, states[0] = 30.107313, states[40]= 0.160111
Saving checkpoint... 
Iteration: 1764428357, states[0] = -67.409480, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1777700155, states[0] = -95.135994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790418737, states[0] = 21.250318, states[40]= 0.010854
Saving checkpoint... 
Iteration: 1802146973, states[0] = -66.331318, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1814245162, states[0] = -94.890526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827497341, states[0] = -95.010888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839876074, states[0] = -94.973667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846997901, states[0] = -94.997463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860216039, states[0] = -94.812505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873885129, states[0] = -94.963041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887529491, states[0] = 19.479748, states[40]= 0.005478
Saving checkpoint... 
Iteration: 1899188043, states[0] = -94.741130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912526553, states[0] = 20.230445, states[40]= 0.005893
Saving checkpoint... 
Iteration: 1925113028, states[0] = -26.466809, states[40]= 0.000713
Saving checkpoint... 
Iteration: 1937711732, states[0] = -94.793064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950852332, states[0] = -94.941901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961413684, states[0] = -94.964164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975496602, states[0] = -94.979473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988232648, states[0] = -94.829091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001448070, states[0] = -94.971615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014483926, states[0] = -94.977481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027693985, states[0] = -94.754771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040676556, states[0] = -94.459008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053554910, states[0] = 11.181457, states[40]= 0.004769
Saving checkpoint... 
Iteration: 2067113352, states[0] = -26.650946, states[40]= 0.000705
Saving checkpoint... 
Iteration: 2079826376, states[0] = -94.926569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088202542, states[0] = -94.773304, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.855220
 - CaMKt in component CaMK (millimolar): 0.007668
 - cass in component intracellular_ions (millimolar): 0.000076
 - nai in component intracellular_ions (millimolar): 6.910580
 - nass in component intracellular_ions (millimolar): 6.910643
 - ki in component intracellular_ions (millimolar): 145.056138
 - kss in component intracellular_ions (millimolar): 145.056118
 - cansr in component intracellular_ions (millimolar): 1.352733
 - cajsr in component intracellular_ions (millimolar): 1.313528
 - cai in component intracellular_ions (millimolar): 0.000077
 - m in component INa (dimensionless): 0.003636
 - hf in component INa (dimensionless): 0.879189
 - hs in component INa (dimensionless): 0.879185
 - j in component INa (dimensionless): 0.879155
 - hsp in component INa (dimensionless): 0.724302
 - jp in component INa (dimensionless): 0.879134
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707252
 - hLp in component INaL (dimensionless): 0.446445
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.614326
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.687975
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930470
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999869
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001759
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330880
 - xs1 in component IKs (dimensionless): 0.252771
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997349
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:51:30 (549474): called boinc_finish(0)

</stderr_txt>
]]>


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