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Task 55425418

Name HuVeMOp_20240630114043648578_ORdGradInc_k_25-Pueyo_APDR-conf_293_1
Workunit 26319224
Created 30 Jun 2024, 9:41:26 UTC
Sent 30 Jun 2024, 11:13:58 UTC
Report deadline 3 Jul 2024, 20:49:58 UTC
Received 1 Jul 2024, 6:12:26 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236921
Run time 2 hours 37 min 6 sec
CPU time 2 hours 32 min 40 sec
Validate state Valid
Credit 60.78
Device peak FLOPS 4.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.96 MB
Peak swap size 4.10 GB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630114043648578_ORdGradInc_k_25-Pueyo_APDR-conf_293.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630114043648578_ORdGradInc_k_25-Pueyo_APDR-conf_293_1_r124760911_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630114043648578_ORdGradInc_k_25-Pueyo_APDR-conf_293_1_r124760911_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 109.256712
     * GNaL_b in INaL: 0.006886
     * Gto_b in Ito: 0.076876
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031534
     * GKs_b in IKs: 0.001767
     * GK1_b in IK1: 0.170991
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.346543
     * GKb_b in IKb: 0.003931
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027809
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 24833519, states[0] = -94.956245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50673835, states[0] = -94.642012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76015975, states[0] = 22.774501, states[40]= 0.016336
Saving checkpoint... 
Iteration: 101473172, states[0] = -94.958323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126432197, states[0] = -94.949027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152121683, states[0] = -38.162742, states[40]= 0.000179
Saving checkpoint... 
Iteration: 177608439, states[0] = -25.861879, states[40]= 0.000704
Saving checkpoint... 
Iteration: 202858601, states[0] = -94.924837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227963112, states[0] = -94.952879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253718462, states[0] = -94.796255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279558151, states[0] = 8.718720, states[40]= 0.005012
Saving checkpoint... 
Iteration: 304297077, states[0] = -94.888921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329391721, states[0] = -94.936612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355577256, states[0] = -0.428853, states[40]= 0.004264
Saving checkpoint... 
Iteration: 381213943, states[0] = -94.788389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408118039, states[0] = -34.663165, states[40]= 0.000288
Saving checkpoint... 
Iteration: 433667378, states[0] = -93.545792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458878525, states[0] = -94.932178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484053417, states[0] = 10.656601, states[40]= 0.005087
Saving checkpoint... 
Iteration: 508468661, states[0] = -94.953474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532962796, states[0] = -94.952552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558346522, states[0] = -94.919001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583604817, states[0] = -22.538290, states[40]= 0.000859
Saving checkpoint... 
Iteration: 608565430, states[0] = 5.555610, states[40]= 0.004857
Saving checkpoint... 
Iteration: 634022741, states[0] = 21.317240, states[40]= 0.008355
Saving checkpoint... 
Iteration: 659271000, states[0] = -94.865609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684947040, states[0] = -94.949757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709939767, states[0] = -94.948353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735351504, states[0] = -94.921207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760739857, states[0] = -94.828639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785918323, states[0] = -94.943617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811715789, states[0] = -94.791321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837179410, states[0] = -94.699034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861963092, states[0] = -94.952397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887661640, states[0] = -88.942396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912861332, states[0] = -94.925352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937939327, states[0] = -94.948127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963909558, states[0] = -94.941304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989085103, states[0] = -5.488412, states[40]= 0.003340
Saving checkpoint... 
Iteration: 1014749873, states[0] = -94.841641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039977778, states[0] = -94.954463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065206971, states[0] = -94.775476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090120844, states[0] = -37.303023, states[40]= 0.000202
Saving checkpoint... 
Iteration: 1115695128, states[0] = -94.752862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141054937, states[0] = 10.042742, states[40]= 0.005064
Saving checkpoint... 
Iteration: 1166161177, states[0] = -88.296802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191116938, states[0] = -33.637655, states[40]= 0.000328
Saving checkpoint... 
Iteration: 1216886920, states[0] = -94.934543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242714164, states[0] = -94.788242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267432910, states[0] = -94.946614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292837919, states[0] = -94.914283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318446363, states[0] = -94.949244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343291155, states[0] = -94.883553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368884674, states[0] = -94.933715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394339954, states[0] = -94.915263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419043033, states[0] = 14.693510, states[40]= 0.005332
Saving checkpoint... 
Iteration: 1445114156, states[0] = -31.066801, states[40]= 0.000444
Saving checkpoint... 
Iteration: 1470606294, states[0] = -23.882713, states[40]= 0.000796
Saving checkpoint... 
Iteration: 1496627404, states[0] = -43.731387, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1521547726, states[0] = -95.146913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546389909, states[0] = -95.077509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572088199, states[0] = -22.994230, states[40]= 0.000853
Saving checkpoint... 
Iteration: 1596664316, states[0] = -0.647731, states[40]= 0.004761
Saving checkpoint... 
Iteration: 1621816619, states[0] = 22.638218, states[40]= 0.016561
Saving checkpoint... 
Iteration: 1646774591, states[0] = -9.214070, states[40]= 0.002852
Saving checkpoint... 
Iteration: 1672109725, states[0] = -95.128208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696828690, states[0] = 18.178075, states[40]= 0.007647
Saving checkpoint... 
Iteration: 1722644707, states[0] = 10.665149, states[40]= 0.006001
Saving checkpoint... 
Iteration: 1748566132, states[0] = -95.038495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773831688, states[0] = -95.160130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798325269, states[0] = -66.374622, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1824702810, states[0] = -94.796412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849805219, states[0] = -94.908234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875126684, states[0] = -43.490150, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1900823908, states[0] = -94.909182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926762465, states[0] = -94.857231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951063736, states[0] = 6.301277, states[40]= 0.004901
Saving checkpoint... 
Iteration: 1977046701, states[0] = 13.290898, states[40]= 0.005219
Saving checkpoint... 
Iteration: 2002300138, states[0] = -94.890301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027425098, states[0] = -94.944462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052495897, states[0] = -94.956121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077884099, states[0] = -94.933055, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.832409
 - CaMKt in component CaMK (millimolar): 0.007033
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.647571
 - nass in component intracellular_ions (millimolar): 6.647631
 - ki in component intracellular_ions (millimolar): 145.328771
 - kss in component intracellular_ions (millimolar): 145.328752
 - cansr in component intracellular_ions (millimolar): 1.319367
 - cajsr in component intracellular_ions (millimolar): 1.281263
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003644
 - hf in component INa (dimensionless): 0.878791
 - hs in component INa (dimensionless): 0.878786
 - j in component INa (dimensionless): 0.878758
 - hsp in component INa (dimensionless): 0.723555
 - jp in component INa (dimensionless): 0.878739
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707727
 - hLp in component INaL (dimensionless): 0.448904
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.618689
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.692852
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932922
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999876
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001645
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.342211
 - xs1 in component IKs (dimensionless): 0.244764
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997355
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:27:09 (15876): called boinc_finish(0)

</stderr_txt>
]]>