𝕏

Task 55425362

Name HuVeMOp_20240630114043648578_ORdGradInc_k_25-Pueyo_APDR-conf_987_1
Workunit 26319196
Created 30 Jun 2024, 9:41:21 UTC
Sent 30 Jun 2024, 11:16:37 UTC
Report deadline 3 Jul 2024, 20:52:37 UTC
Received 30 Jun 2024, 14:54:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240368
Run time 2 hours 51 min 26 sec
CPU time 2 hours 45 min 15 sec
Validate state Valid
Credit 57.77
Device peak FLOPS 4.18 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.11 MB
Peak swap size 6.23 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630114043648578_ORdGradInc_k_25-Pueyo_APDR-conf_987.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630114043648578_ORdGradInc_k_25-Pueyo_APDR-conf_987_1_r676154501_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630114043648578_ORdGradInc_k_25-Pueyo_APDR-conf_987_1_r676154501_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.136030
     * GNaL_b in INaL: 0.004875
     * Gto_b in Ito: 0.071040
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033487
     * GKs_b in IKs: 0.001835
     * GK1_b in IK1: 0.153471
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.019772
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027240
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13622365, states[0] = -56.110389, states[40]= 0.000009
Saving checkpoint... 
Iteration: 27221875, states[0] = -94.783895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40868308, states[0] = -94.892492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54557807, states[0] = 5.812080, states[40]= 0.005001
Saving checkpoint... 
Iteration: 68275701, states[0] = -94.813206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81909953, states[0] = -94.881363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95592244, states[0] = -19.773832, states[40]= 0.000987
Saving checkpoint... 
Iteration: 109252477, states[0] = -94.776601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122684817, states[0] = -94.656956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136325346, states[0] = -94.838428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149801919, states[0] = -94.821916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163381130, states[0] = -94.863236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177011484, states[0] = 23.836532, states[40]= 0.038245
Saving checkpoint... 
Iteration: 190642370, states[0] = -75.324314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204295506, states[0] = -94.815766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217922371, states[0] = -94.874517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231489006, states[0] = -94.886281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244517245, states[0] = 22.120747, states[40]= 0.014282
Saving checkpoint... 
Iteration: 257487738, states[0] = -94.886037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270468705, states[0] = -94.883326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283077444, states[0] = -5.455752, states[40]= 0.003424
Saving checkpoint... 
Iteration: 295892442, states[0] = -94.866038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308814220, states[0] = -94.829227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321735001, states[0] = -94.748011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335294587, states[0] = -94.814672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348842066, states[0] = -94.845543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361837075, states[0] = -94.842921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374968443, states[0] = -94.883189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388543652, states[0] = 12.620564, states[40]= 0.005456
Saving checkpoint... 
Iteration: 402263771, states[0] = -94.785173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416093780, states[0] = -20.992715, states[40]= 0.000896
Saving checkpoint... 
Iteration: 429830299, states[0] = -94.839123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443556954, states[0] = 6.651242, states[40]= 0.005038
Saving checkpoint... 
Iteration: 457450955, states[0] = -94.880197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471247763, states[0] = -94.765774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484867595, states[0] = -94.857044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498557436, states[0] = 6.420994, states[40]= 0.005023
Saving checkpoint... 
Iteration: 512334953, states[0] = -94.841685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526168432, states[0] = -94.567646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539876101, states[0] = -94.860288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553701249, states[0] = -94.688694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567407914, states[0] = -94.870434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581177357, states[0] = -94.634001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594987676, states[0] = -94.885786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608713895, states[0] = -94.712942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622565878, states[0] = 2.106379, states[40]= 0.004673
Saving checkpoint... 
Iteration: 636460016, states[0] = -94.881686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650223435, states[0] = -94.729563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663900893, states[0] = -94.868392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677728874, states[0] = -94.738390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691477136, states[0] = -94.884306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705281305, states[0] = -94.802883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719112611, states[0] = -40.331479, states[40]= 0.000113
Saving checkpoint... 
Iteration: 732935421, states[0] = -94.876987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746741127, states[0] = -94.756625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760536746, states[0] = 15.492011, states[40]= 0.005881
Saving checkpoint... 
Iteration: 774236236, states[0] = -94.749582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788189735, states[0] = -94.664448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801937206, states[0] = -94.877324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815618318, states[0] = -46.424476, states[40]= 0.000044
Saving checkpoint... 
Iteration: 829444983, states[0] = -94.878870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843338471, states[0] = -94.843398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857258813, states[0] = -94.779260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871188234, states[0] = -94.661115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884898152, states[0] = -94.867459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898690591, states[0] = -94.666244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912528040, states[0] = 18.782464, states[40]= 0.007053
Saving checkpoint... 
Iteration: 926514796, states[0] = 22.797917, states[40]= 0.020397
Saving checkpoint... 
Iteration: 940463514, states[0] = -94.882097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954322474, states[0] = -94.834177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968252670, states[0] = -94.771775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982130239, states[0] = -59.662845, states[40]= 0.000005
Saving checkpoint... 
Iteration: 996112939, states[0] = -40.675927, states[40]= 0.000107
Saving checkpoint... 
Iteration: 1010154979, states[0] = -92.237977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023862325, states[0] = -94.854585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037738818, states[0] = -94.753190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051704891, states[0] = -94.695662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065605620, states[0] = -33.098878, states[40]= 0.000303
Saving checkpoint... 
Iteration: 1079568656, states[0] = 0.520652, states[40]= 0.004485
Saving checkpoint... 
Iteration: 1093597749, states[0] = -25.049878, states[40]= 0.000665
Saving checkpoint... 
Iteration: 1107606960, states[0] = -34.473637, states[40]= 0.000255
Saving checkpoint... 
Iteration: 1121663736, states[0] = -94.407644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135689247, states[0] = -94.663192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149619250, states[0] = -47.437859, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1163457297, states[0] = -94.880936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177209400, states[0] = -94.704283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191041900, states[0] = 13.364277, states[40]= 0.005540
Saving checkpoint... 
Iteration: 1204686521, states[0] = -94.657123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218412266, states[0] = -94.871246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232378358, states[0] = -94.860735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246185115, states[0] = -94.653915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259950344, states[0] = -94.879646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273700611, states[0] = -94.687009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287457323, states[0] = -94.880873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301256487, states[0] = -94.776260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315018053, states[0] = 21.898106, states[40]= 0.012973
Saving checkpoint... 
Iteration: 1328796473, states[0] = -94.815644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342489241, states[0] = -94.885577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356222890, states[0] = -94.728262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369969542, states[0] = -94.882813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383691187, states[0] = -94.667262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397545911, states[0] = 11.648859, states[40]= 0.005364
Saving checkpoint... 
Iteration: 1411248519, states[0] = -94.766245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425028449, states[0] = 18.638876, states[40]= 0.006967
Saving checkpoint... 
Iteration: 1438925844, states[0] = -94.874480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452811759, states[0] = -94.826917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466441749, states[0] = -94.877887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480361730, states[0] = -94.854084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494234051, states[0] = -94.745934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507979427, states[0] = -94.981202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521031528, states[0] = 16.224123, states[40]= 0.007390
Saving checkpoint... 
Iteration: 1531247909, states[0] = 7.378192, states[40]= 0.005804
Saving checkpoint... 
Iteration: 1544982746, states[0] = -95.158548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1558748997, states[0] = -95.134143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572512135, states[0] = -95.088756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586335940, states[0] = -95.125904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600035234, states[0] = -93.014211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613675575, states[0] = -95.169463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627250901, states[0] = 5.094091, states[40]= 0.005592
Saving checkpoint... 
Iteration: 1640567415, states[0] = -95.002377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1654158064, states[0] = -95.155104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667681834, states[0] = -95.176108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681195698, states[0] = -95.186164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694748222, states[0] = 6.711415, states[40]= 0.005771
Saving checkpoint... 
Iteration: 1708315732, states[0] = -65.574312, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1721894250, states[0] = -95.064159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735394694, states[0] = -95.065051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748519405, states[0] = -70.836044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1761253760, states[0] = -95.151201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773801329, states[0] = -95.077707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786853719, states[0] = 3.264625, states[40]= 0.005380
Saving checkpoint... 
Iteration: 1799250854, states[0] = -94.941810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812003265, states[0] = 37.203365, states[40]= 0.141319
Saving checkpoint... 
Iteration: 1823939863, states[0] = -94.913733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834820858, states[0] = -94.859413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847328344, states[0] = -94.855750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860116777, states[0] = -45.538795, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1873527776, states[0] = 18.786737, states[40]= 0.007102
Saving checkpoint... 
Iteration: 1887113249, states[0] = -41.341455, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1900686518, states[0] = -94.660611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914257205, states[0] = -94.779367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927788825, states[0] = -94.810673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941391714, states[0] = -94.866016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954710540, states[0] = -94.706771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967534378, states[0] = 16.424414, states[40]= 0.006102
Saving checkpoint... 
Iteration: 1980883541, states[0] = -94.862483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994484481, states[0] = -94.884810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008123608, states[0] = -52.236757, states[40]= 0.000017
Saving checkpoint... 
Iteration: 2021545281, states[0] = 11.919898, states[40]= 0.005388
Saving checkpoint... 
Iteration: 2035231666, states[0] = -94.742039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048627684, states[0] = -56.770120, states[40]= 0.000008
Saving checkpoint... 
Iteration: 2062163749, states[0] = -94.407946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075773997, states[0] = -94.795047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089393686, states[0] = -94.865404, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.762302
 - CaMKt in component CaMK (millimolar): 0.006535
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.602785
 - nass in component intracellular_ions (millimolar): 6.602843
 - ki in component intracellular_ions (millimolar): 145.378946
 - kss in component intracellular_ions (millimolar): 145.378928
 - cansr in component intracellular_ions (millimolar): 1.297097
 - cajsr in component intracellular_ions (millimolar): 1.260587
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003670
 - hf in component INa (dimensionless): 0.877558
 - hs in component INa (dimensionless): 0.877554
 - j in component INa (dimensionless): 0.877524
 - hsp in component INa (dimensionless): 0.721244
 - jp in component INa (dimensionless): 0.877505
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.708285
 - hLp in component INaL (dimensionless): 0.454130
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.630148
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.706506
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940685
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999905
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001563
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329551
 - xs1 in component IKs (dimensionless): 0.225594
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997374
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:51:58 (4628): called boinc_finish(0)

</stderr_txt>
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