𝕏

Task 55425193

Name HuVeMOp_20240630114043648578_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_165_0
Workunit 26319112
Created 30 Jun 2024, 9:41:16 UTC
Sent 30 Jun 2024, 11:12:07 UTC
Report deadline 3 Jul 2024, 14:04:55 UTC
Received 30 Jun 2024, 19:20:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 49 min 12 sec
CPU time 1 hours 43 min 13 sec
Validate state Valid
Credit 49.02
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.80 MB
Peak swap size 4.13 GB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630114043648578_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_165.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630114043648578_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_165_0_r2061647129_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630114043648578_ORdGradInc_k_25-CLVPET_Block_Kr_15-conf_165_0_r2061647129_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 91.207141
     * GNaL_b in INaL: 0.006559
     * Gto_b in Ito: 0.078361
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.025389
     * GKs_b in IKs: 0.001880
     * GK1_b in IK1: 0.168410
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 69.962852
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044064
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14013126, states[0] = 28.888303, states[40]= 0.016785
Saving checkpoint... 
Iteration: 26758988, states[0] = -94.634544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40080055, states[0] = 7.434589, states[40]= 0.004625
Saving checkpoint... 
Iteration: 52365100, states[0] = -94.769408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65977279, states[0] = -94.819374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78780072, states[0] = -94.654715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90841642, states[0] = -94.742136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104029867, states[0] = 26.334932, states[40]= 0.001487
Saving checkpoint... 
Iteration: 117387922, states[0] = -94.777932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130481845, states[0] = -94.815539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143582041, states[0] = 6.740340, states[40]= 0.004711
Saving checkpoint... 
Iteration: 156449415, states[0] = -94.805716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169248037, states[0] = -94.575355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181765178, states[0] = -94.618806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194028135, states[0] = 26.835033, states[40]= 0.001474
Saving checkpoint... 
Iteration: 207572115, states[0] = 11.236161, states[40]= 0.004244
Saving checkpoint... 
Iteration: 220325303, states[0] = -94.720916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232095047, states[0] = -0.200495, states[40]= 0.004608
Saving checkpoint... 
Iteration: 245027094, states[0] = 27.112308, states[40]= 0.001479
Saving checkpoint... 
Iteration: 257208820, states[0] = -94.402137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269983631, states[0] = -94.814596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283287332, states[0] = -94.663898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296015682, states[0] = 29.092097, states[40]= 0.007708
Saving checkpoint... 
Iteration: 309202582, states[0] = -94.120694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322353483, states[0] = -94.749900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335466963, states[0] = -94.810024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349029080, states[0] = 26.576870, states[40]= 0.001483
Saving checkpoint... 
Iteration: 362194692, states[0] = -91.365737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375373712, states[0] = -94.766069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388916655, states[0] = -94.791316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402353244, states[0] = -94.749365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414478236, states[0] = -94.812698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427410113, states[0] = -94.787986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440124201, states[0] = -22.049713, states[40]= 0.001669
Saving checkpoint... 
Iteration: 453565384, states[0] = 13.995958, states[40]= 0.003784
Saving checkpoint... 
Iteration: 466767066, states[0] = -94.621813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479606534, states[0] = -8.044474, states[40]= 0.003136
Saving checkpoint... 
Iteration: 492079772, states[0] = 7.829072, states[40]= 0.004634
Saving checkpoint... 
Iteration: 504964071, states[0] = -94.808525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517127228, states[0] = -24.348055, states[40]= 0.001742
Saving checkpoint... 
Iteration: 529742324, states[0] = -94.557329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542579945, states[0] = 7.748262, states[40]= 0.004641
Saving checkpoint... 
Iteration: 555382219, states[0] = -94.771284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568797791, states[0] = -94.680768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581781225, states[0] = -94.651184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595449624, states[0] = -94.803656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608922885, states[0] = -94.793278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621831906, states[0] = -94.726964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635548019, states[0] = 20.405280, states[40]= 0.002442
Saving checkpoint... 
Iteration: 649169945, states[0] = -59.533189, states[40]= 0.000027
Saving checkpoint... 
Iteration: 661809452, states[0] = -94.698212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674795665, states[0] = -94.676847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687981021, states[0] = -94.812300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701582451, states[0] = 6.555500, states[40]= 0.004725
Saving checkpoint... 
Iteration: 714994259, states[0] = -94.815193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728419161, states[0] = -94.791131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741605378, states[0] = -7.167812, states[40]= 0.003341
Saving checkpoint... 
Iteration: 754336918, states[0] = -94.731937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767047959, states[0] = 20.426445, states[40]= 0.002438
Saving checkpoint... 
Iteration: 779818740, states[0] = -94.710409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792999136, states[0] = -94.815887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806697981, states[0] = -93.193123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819650164, states[0] = -42.029277, states[40]= 0.000390
Saving checkpoint... 
Iteration: 832286453, states[0] = -94.660086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850578500, states[0] = 8.418793, states[40]= 0.004582
Saving checkpoint... 
Iteration: 867262719, states[0] = -94.610096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868534839, states[0] = 24.849301, states[40]= 0.001665
Saving checkpoint... 
Iteration: 880527563, states[0] = 26.990348, states[40]= 0.001476
Saving checkpoint... 
Iteration: 893881932, states[0] = -94.769748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905658874, states[0] = -49.415114, states[40]= 0.000136
Saving checkpoint... 
Iteration: 917719257, states[0] = -94.479132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930579178, states[0] = 8.106096, states[40]= 0.004611
Saving checkpoint... 
Iteration: 943830102, states[0] = -94.723630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956157627, states[0] = -48.327504, states[40]= 0.000160
Saving checkpoint... 
Iteration: 969494260, states[0] = -94.814185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981886625, states[0] = -94.772464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994180804, states[0] = -71.573696, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1007262154, states[0] = -94.608186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020291465, states[0] = -94.668314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032306445, states[0] = -94.692354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044965219, states[0] = -94.806715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056910046, states[0] = -94.785454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070209120, states[0] = -94.403681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082797278, states[0] = -94.677881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095688954, states[0] = -84.086091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1108089838, states[0] = 2.774287, states[40]= 0.004795
Saving checkpoint... 
Iteration: 1121516838, states[0] = 29.009687, states[40]= 0.005559
Saving checkpoint... 
Iteration: 1133470538, states[0] = -94.807845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147530566, states[0] = 26.153887, states[40]= 0.001513
Saving checkpoint... 
Iteration: 1160487533, states[0] = -94.811956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173848095, states[0] = -94.741535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186804724, states[0] = -94.689166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199209514, states[0] = -94.409196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211466177, states[0] = -94.806327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224023638, states[0] = 27.941729, states[40]= 0.001677
Saving checkpoint... 
Iteration: 1237083647, states[0] = 5.972314, states[40]= 0.004756
Saving checkpoint... 
Iteration: 1250104786, states[0] = -6.724559, states[40]= 0.003443
Saving checkpoint... 
Iteration: 1263512140, states[0] = 29.161199, states[40]= 0.023282
Saving checkpoint... 
Iteration: 1276607408, states[0] = -8.714982, states[40]= 0.002980
Saving checkpoint... 
Iteration: 1289944737, states[0] = -94.799219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302608644, states[0] = -9.679890, states[40]= 0.002761
Saving checkpoint... 
Iteration: 1315400128, states[0] = -94.779185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328395296, states[0] = -94.776381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341758688, states[0] = -94.598388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354185806, states[0] = -78.926437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1367250583, states[0] = -94.577260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380068350, states[0] = 12.806205, states[40]= 0.003998
Saving checkpoint... 
Iteration: 1393859953, states[0] = -94.751256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406347525, states[0] = -94.740068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420080917, states[0] = 7.291706, states[40]= 0.004677
Saving checkpoint... 
Iteration: 1432615845, states[0] = -15.465516, states[40]= 0.001775
Saving checkpoint... 
Iteration: 1445876352, states[0] = -94.763712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458988682, states[0] = -94.811032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471407705, states[0] = -94.782619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484489827, states[0] = -94.811186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497035267, states[0] = 24.713862, states[40]= 0.001684
Saving checkpoint... 
Iteration: 1509011126, states[0] = 29.914554, states[40]= 0.033263
Saving checkpoint... 
Iteration: 1521801150, states[0] = -54.778108, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1533774993, states[0] = 27.396593, states[40]= 0.000986
Saving checkpoint... 
Iteration: 1546939513, states[0] = -70.082649, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1558283388, states[0] = -94.386738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570914759, states[0] = -94.604938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582728111, states[0] = -94.516681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595337476, states[0] = -94.364275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608213856, states[0] = -94.495611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621215471, states[0] = -94.431281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633887841, states[0] = -94.420679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646504358, states[0] = -94.413186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659778626, states[0] = -94.402033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671848367, states[0] = -94.401827, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.272247
 - CaMKt in component CaMK (millimolar): 0.001113
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.405705
 - nass in component intracellular_ions (millimolar): 6.405787
 - ki in component intracellular_ions (millimolar): 145.495227
 - kss in component intracellular_ions (millimolar): 145.495216
 - cansr in component intracellular_ions (millimolar): 1.545034
 - cajsr in component intracellular_ions (millimolar): 1.545103
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.003856
 - hf in component INa (dimensionless): 0.868638
 - hs in component INa (dimensionless): 0.868638
 - j in component INa (dimensionless): 0.868639
 - hsp in component INa (dimensionless): 0.704796
 - jp in component INa (dimensionless): 0.868640
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.712253
 - hLp in component INaL (dimensionless): 0.519481
 - a in component Ito (dimensionless): 0.000650
 - iF in component Ito (dimensionless): 0.999854
 - iS in component Ito (dimensionless): 0.997591
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999854
 - iSp in component Ito (dimensionless): 0.999190
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998690
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002842
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001974
 - xs1 in component IKs (dimensionless): 0.025300
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997498
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:33:38 (97989): called boinc_finish(0)

</stderr_txt>
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