𝕏

Task 55422360

Name HuVeMOp_20240630111542321423_ORdGradInc_k_25-Drouin_MID_3000-conf_140_1
Workunit 26317726
Created 30 Jun 2024, 9:16:24 UTC
Sent 30 Jun 2024, 10:52:20 UTC
Report deadline 3 Jul 2024, 10:52:20 UTC
Received 2 Jul 2024, 2:21:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 2 hours 59 min 33 sec
CPU time 1 hours 29 min 51 sec
Validate state Valid
Credit 44.09
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630111542321423_ORdGradInc_k_25-Drouin_MID_3000-conf_140.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630111542321423_ORdGradInc_k_25-Drouin_MID_3000-conf_140_1_r718401038_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630111542321423_ORdGradInc_k_25-Drouin_MID_3000-conf_140_1_r718401038_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.572979
     * GNaL_b in INaL: 0.005976
     * Gto_b in Ito: 0.083770
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033112
     * GKs_b in IKs: 0.002117
     * GK1_b in IK1: 0.181211
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 65.680425
     * GKb_b in IKb: 0.003777
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054862
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7933312, states[0] = -94.167954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16424073, states[0] = -94.253786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 24493628, states[0] = -94.200947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33052379, states[0] = 31.955353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40547824, states[0] = 32.664033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48811994, states[0] = -94.285428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 56261570, states[0] = -94.291119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 63785238, states[0] = -94.297087, states[40]= 0.000001
Saving checkpoint... 
Iteration: 73179597, states[0] = -94.292569, states[40]= 0.000001
Saving checkpoint... 
Iteration: 80533819, states[0] = -94.301628, states[40]= 0.000001
Saving checkpoint... 
Iteration: 88930281, states[0] = -94.198640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 97082930, states[0] = -94.306724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 105408288, states[0] = -94.176724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 113485943, states[0] = -94.314568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 121594621, states[0] = 15.985160, states[40]= 0.000014
Saving checkpoint... 
Iteration: 129708743, states[0] = -94.319245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 138143024, states[0] = -5.168500, states[40]= 0.000563
Saving checkpoint... 
Iteration: 145797465, states[0] = -93.883039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154386274, states[0] = -94.306704, states[40]= 0.000001
Saving checkpoint... 
Iteration: 164649791, states[0] = -94.314687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 172602508, states[0] = 12.634410, states[40]= 0.000033
Saving checkpoint... 
Iteration: 179833801, states[0] = -94.309255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 187497230, states[0] = -94.305012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 196147196, states[0] = -94.315513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 204347904, states[0] = -94.067527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212116125, states[0] = -94.313121, states[40]= 0.000001
Saving checkpoint... 
Iteration: 220420357, states[0] = -94.307082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 228403350, states[0] = -94.180502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 236854185, states[0] = -94.308787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 245455431, states[0] = -94.321870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 253809505, states[0] = -93.939458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262837283, states[0] = -94.037011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271174994, states[0] = -94.313980, states[40]= 0.000001
Saving checkpoint... 
Iteration: 278694359, states[0] = -94.313202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 286749950, states[0] = -87.741447, states[40]= 0.000003
Saving checkpoint... 
Iteration: 295169191, states[0] = -94.313767, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303230455, states[0] = -59.581360, states[40]= 0.000159
Saving checkpoint... 
Iteration: 311758743, states[0] = -94.310515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 321215883, states[0] = -47.232683, states[40]= 0.000909
Saving checkpoint... 
Iteration: 329326071, states[0] = -94.323388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 337791104, states[0] = -93.855735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345987623, states[0] = -94.319127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 354578696, states[0] = -94.302897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 363356972, states[0] = -94.088766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371319029, states[0] = -94.322646, states[40]= 0.000001
Saving checkpoint... 
Iteration: 379433721, states[0] = -94.304150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 388143948, states[0] = -94.312893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 397048628, states[0] = -94.316057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 406059839, states[0] = -94.315489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 415369401, states[0] = -94.305207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423771492, states[0] = -94.321532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 432434101, states[0] = -94.216717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 440354274, states[0] = -94.320883, states[40]= 0.000001
Saving checkpoint... 
Iteration: 448731621, states[0] = -60.696053, states[40]= 0.000135
Saving checkpoint... 
Iteration: 458199830, states[0] = -94.318389, states[40]= 0.000001
Saving checkpoint... 
Iteration: 467343265, states[0] = -94.320527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 475716944, states[0] = -48.078766, states[40]= 0.000814
Saving checkpoint... 
Iteration: 486526184, states[0] = -94.282189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495990158, states[0] = -94.316137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 505446063, states[0] = -94.301376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514780777, states[0] = -93.798909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522951813, states[0] = -94.316844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 531054399, states[0] = 29.862168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539615978, states[0] = -94.310920, states[40]= 0.000001
Saving checkpoint... 
Iteration: 549391144, states[0] = -94.155152, states[40]= 0.000001
Saving checkpoint... 
Iteration: 557679620, states[0] = -94.308370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 567054254, states[0] = 29.901255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574861982, states[0] = -94.096505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583631008, states[0] = 0.512905, states[40]= 0.000322
Saving checkpoint... 
Iteration: 593515289, states[0] = -94.313388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 602400362, states[0] = -94.316753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610883851, states[0] = -94.141017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619545427, states[0] = 31.951181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628774867, states[0] = -93.763469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638121040, states[0] = -94.306338, states[40]= 0.000001
Saving checkpoint... 
Iteration: 647105951, states[0] = -94.303422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 656243467, states[0] = -94.316449, states[40]= 0.000001
Saving checkpoint... 
Iteration: 664849188, states[0] = -94.062986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673004633, states[0] = -94.312210, states[40]= 0.000001
Saving checkpoint... 
Iteration: 680988880, states[0] = -94.296885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 689055296, states[0] = -94.289477, states[40]= 0.000001
Saving checkpoint... 
Iteration: 697503574, states[0] = 19.970221, states[40]= 1.050999
Saving checkpoint... 
Iteration: 705636986, states[0] = -94.307472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713896215, states[0] = -94.298654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 722061881, states[0] = -94.290949, states[40]= 0.000001
Saving checkpoint... 
Iteration: 730042658, states[0] = -94.309793, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738470998, states[0] = -94.244750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 746280595, states[0] = -94.315357, states[40]= 0.000001
Saving checkpoint... 
Iteration: 754206170, states[0] = -94.303661, states[40]= 0.000001
Saving checkpoint... 
Iteration: 762505175, states[0] = -94.266453, states[40]= 0.000001
Saving checkpoint... 
Iteration: 770807770, states[0] = -94.300100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 778694800, states[0] = -32.656236, states[40]= 0.004181
Saving checkpoint... 
Iteration: 786708694, states[0] = -94.312514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 794677834, states[0] = -94.303825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 803118528, states[0] = -94.302708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 810839990, states[0] = -94.313894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 818900647, states[0] = -94.296484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 827014540, states[0] = -94.270076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 835901729, states[0] = -94.166636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 845017384, states[0] = -94.271121, states[40]= 0.000001
Saving checkpoint... 
Iteration: 853211858, states[0] = -94.301541, states[40]= 0.000001
Saving checkpoint... 
Iteration: 862523473, states[0] = 33.255144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871410259, states[0] = -94.295199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 879535171, states[0] = -94.278348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 887619158, states[0] = -94.304038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897494162, states[0] = -94.257462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 907179076, states[0] = -94.301588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 916360579, states[0] = -94.295707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924712336, states[0] = -94.310018, states[40]= 0.000001
Saving checkpoint... 
Iteration: 933339781, states[0] = -94.031390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941868416, states[0] = -94.294984, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950063161, states[0] = -94.286893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 958821812, states[0] = -93.972633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967655884, states[0] = -13.478618, states[40]= 0.000724
Saving checkpoint... 
Iteration: 975659422, states[0] = -94.304963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 984201177, states[0] = -36.536354, states[40]= 0.003046
Saving checkpoint... 
Iteration: 992662461, states[0] = -94.300489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1001645592, states[0] = -94.300897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1009305821, states[0] = -94.295510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1017074189, states[0] = 23.506973, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1026074255, states[0] = 23.483263, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1034052574, states[0] = -94.281824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1042381568, states[0] = -94.292657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1049420933, states[0] = -94.307512, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1057437104, states[0] = -94.290858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065353553, states[0] = -94.066386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073325801, states[0] = -94.308938, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1082027701, states[0] = -94.271245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090016645, states[0] = -94.303682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1098035526, states[0] = 33.331580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106769804, states[0] = -94.294725, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1115302282, states[0] = -94.308243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124207785, states[0] = -94.305893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1132515342, states[0] = 31.634964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140215370, states[0] = -46.792759, states[40]= 0.000961
Saving checkpoint... 
Iteration: 1148694415, states[0] = -94.296365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156537177, states[0] = 33.182085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163988481, states[0] = -94.287481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1172962636, states[0] = -94.287955, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181119128, states[0] = -94.295452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1189578182, states[0] = 22.051021, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1197494405, states[0] = -94.251760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1207177277, states[0] = -94.295816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215004022, states[0] = 20.723687, states[40]= -0.000004
Saving checkpoint... 
Iteration: 1223083624, states[0] = -94.287256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1232025888, states[0] = -94.267528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1240606220, states[0] = 11.066903, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1249017228, states[0] = -94.300574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1258325419, states[0] = -94.290079, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1265876951, states[0] = -94.288440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1274259514, states[0] = -94.304809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1283826406, states[0] = -94.289551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1292764287, states[0] = -94.291287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1301906004, states[0] = -94.286934, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310417855, states[0] = -94.302525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1318474351, states[0] = -94.284827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1327166791, states[0] = -94.293834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1335081577, states[0] = 20.784239, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1343884058, states[0] = -94.286719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1351997520, states[0] = -94.250601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1360189593, states[0] = -94.292416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1369437004, states[0] = -94.284789, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1378387410, states[0] = -94.285954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1388115895, states[0] = -94.290857, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1395642742, states[0] = -94.294814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1403804691, states[0] = -94.287865, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1412368323, states[0] = -94.301724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1420145307, states[0] = -94.292764, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1427656369, states[0] = -94.292235, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1436105009, states[0] = -94.287876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1443202360, states[0] = -37.290550, states[40]= 0.002833
Saving checkpoint... 
Iteration: 1451792371, states[0] = -94.287308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459949327, states[0] = -94.212170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1468097976, states[0] = -94.293482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1475740011, states[0] = -94.288497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1484408803, states[0] = -94.299379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1492066410, states[0] = -94.294125, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.156617
 - CaMKt in component CaMK (millimolar): 0.004441
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 8.218073
 - nass in component intracellular_ions (millimolar): 8.218241
 - ki in component intracellular_ions (millimolar): 143.483610
 - kss in component intracellular_ions (millimolar): 143.483591
 - cansr in component intracellular_ions (millimolar): 1.950593
 - cajsr in component intracellular_ions (millimolar): 1.953067
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003901
 - hf in component INa (dimensionless): 0.866455
 - hs in component INa (dimensionless): 0.866456
 - j in component INa (dimensionless): 0.866462
 - hsp in component INa (dimensionless): 0.700833
 - jp in component INa (dimensionless): 0.866465
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709137
 - hLp in component INaL (dimensionless): 0.511300
 - a in component Ito (dimensionless): 0.000656
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.965333
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.982085
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.986398
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005045
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.032738
 - xs1 in component IKs (dimensionless): 0.090203
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997526
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
03:01:38 (37082): called boinc_finish(0)

</stderr_txt>
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