𝕏

Task 55422358

Name HuVeMOp_20240630111542321423_ORdGradInc_k_25-Drouin_EPI_10000-conf_240_1
Workunit 26317725
Created 30 Jun 2024, 9:16:24 UTC
Sent 30 Jun 2024, 10:52:20 UTC
Report deadline 3 Jul 2024, 10:52:20 UTC
Received 2 Jul 2024, 1:12:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 2 min 23 sec
CPU time 1 hours 29 min 20 sec
Validate state Valid
Credit 44.06
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630111542321423_ORdGradInc_k_25-Drouin_EPI_10000-conf_240.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630111542321423_ORdGradInc_k_25-Drouin_EPI_10000-conf_240_1_r501175892_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630111542321423_ORdGradInc_k_25-Drouin_EPI_10000-conf_240_1_r501175892_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.052734
     * GNaL_b in INaL: 0.004527
     * Gto_b in Ito: 0.096920
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029701
     * GKs_b in IKs: 0.001880
     * GK1_b in IK1: 0.178302
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 69.699204
     * GKb_b in IKb: 0.003741
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.047701
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 300.000000
     * CL_0 in membrane: 10000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9731391, states[0] = -94.369414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19072032, states[0] = -94.308328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28113132, states[0] = -94.276681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37882655, states[0] = -94.258315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48275197, states[0] = -94.248113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56553881, states[0] = -94.257935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64037009, states[0] = -94.243695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73744060, states[0] = -94.244664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82846261, states[0] = -94.248040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92162484, states[0] = -94.253501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100795894, states[0] = -94.282802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108997049, states[0] = -94.249404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117220532, states[0] = -94.256338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125324745, states[0] = -94.124351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133870223, states[0] = -94.251943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141161063, states[0] = -94.275353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148560468, states[0] = -94.253252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157589054, states[0] = -94.256680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166024710, states[0] = -94.280602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173818220, states[0] = -94.253765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181758383, states[0] = -94.264627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190221256, states[0] = -93.747000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198154428, states[0] = -94.255395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206005030, states[0] = -94.281898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214183066, states[0] = -94.253916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221550779, states[0] = -94.268252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231058287, states[0] = -94.280276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239354491, states[0] = -94.253854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247297901, states[0] = -94.259528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255269045, states[0] = -93.977869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263880836, states[0] = -94.254217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272131137, states[0] = -94.260819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280630112, states[0] = -94.288589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288419929, states[0] = -94.254838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295887951, states[0] = -94.285728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303310852, states[0] = -94.255010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310715742, states[0] = -94.289726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318930597, states[0] = -94.253962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326551066, states[0] = -94.268003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334542191, states[0] = -94.253452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342771324, states[0] = -94.256528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351051947, states[0] = -94.280099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359362374, states[0] = -94.253428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367626700, states[0] = -94.257075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375745655, states[0] = -94.289102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383266931, states[0] = -94.254741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390745320, states[0] = -94.289034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398410905, states[0] = -94.254354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406603391, states[0] = -94.266720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413956374, states[0] = -94.253482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421038627, states[0] = -94.280185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431315297, states[0] = -94.272368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439365206, states[0] = -94.253034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447767209, states[0] = -94.256033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456072173, states[0] = -94.278948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463747681, states[0] = -94.253478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472418003, states[0] = -94.257736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482343008, states[0] = -94.258185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490277464, states[0] = -94.006220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497827608, states[0] = -94.255537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505969182, states[0] = -94.282039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514038757, states[0] = -94.252906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521926812, states[0] = -94.261696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530188549, states[0] = -85.904257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 539128116, states[0] = -94.252703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547537538, states[0] = -94.256654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555861995, states[0] = -94.285301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564202005, states[0] = -94.252521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572435975, states[0] = -94.257126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580998928, states[0] = -94.280682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589128738, states[0] = -94.252454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597295056, states[0] = -94.257954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605262208, states[0] = -93.950092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614392152, states[0] = -94.252148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624141319, states[0] = -94.252269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632482485, states[0] = -94.256545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640857728, states[0] = -94.285012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649071847, states[0] = -94.252203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658167515, states[0] = -94.253627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666226834, states[0] = -94.273428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674072780, states[0] = -94.252078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681441307, states[0] = -94.268345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688632357, states[0] = -94.252523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696998111, states[0] = -94.260055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705208517, states[0] = -93.658258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713707515, states[0] = -94.252289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721133963, states[0] = -94.275755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729310585, states[0] = -94.251625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738273072, states[0] = -94.252963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746518172, states[0] = -94.266529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754407045, states[0] = -94.251443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763043726, states[0] = -94.253460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770615650, states[0] = -94.285514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779214719, states[0] = -94.251442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787267095, states[0] = -94.257218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795725558, states[0] = -94.287271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803158395, states[0] = -94.252930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810941498, states[0] = -94.281446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818038987, states[0] = -94.253202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826561525, states[0] = -94.265350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834447417, states[0] = -94.251023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842685099, states[0] = -94.254435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851161059, states[0] = -94.274324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859740421, states[0] = -94.250773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867586160, states[0] = -94.254800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875207237, states[0] = -93.644143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882945124, states[0] = -94.253186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890314965, states[0] = -94.104681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899197097, states[0] = -94.250858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906789461, states[0] = -94.261464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915939091, states[0] = -94.281006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924527808, states[0] = -94.250536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933209352, states[0] = -94.252150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941113526, states[0] = -94.275273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949314292, states[0] = -94.250528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958174793, states[0] = -94.252115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966449875, states[0] = -94.266756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974213562, states[0] = -94.250472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982188866, states[0] = -94.256867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990092188, states[0] = 10.516560, states[40]= 0.000035
Saving checkpoint... 
Iteration: 999212152, states[0] = -94.250348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007524436, states[0] = -94.254438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016012615, states[0] = -94.278074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023862724, states[0] = -94.250548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031933563, states[0] = -94.259083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040196157, states[0] = -92.810646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047441114, states[0] = -94.254730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056103027, states[0] = -94.275017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064506071, states[0] = -94.249847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072631811, states[0] = -94.253546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080546040, states[0] = -94.277151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088282199, states[0] = -94.251199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097509205, states[0] = -94.254076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105575007, states[0] = -94.280691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113800130, states[0] = -94.250175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121683700, states[0] = -94.261891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129120053, states[0] = -94.249772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137549987, states[0] = -94.253648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145640502, states[0] = -94.284749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154338598, states[0] = -94.249491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162652764, states[0] = -94.252995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170360413, states[0] = -94.178374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178443558, states[0] = -94.250408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186225069, states[0] = -94.270890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195148920, states[0] = -34.968368, states[40]= 0.000517
Saving checkpoint... 
Iteration: 1203048509, states[0] = -94.251254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211724799, states[0] = -94.260838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221398596, states[0] = -94.266554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230511328, states[0] = -94.269834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239262657, states[0] = -94.249116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247630290, states[0] = -94.252682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256711899, states[0] = -94.260801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265028026, states[0] = 25.011611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272990283, states[0] = -94.251091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280363427, states[0] = -94.181553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287529277, states[0] = -94.253017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296416743, states[0] = -94.265796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305125300, states[0] = -11.468720, states[40]= 0.000338
Saving checkpoint... 
Iteration: 1312822070, states[0] = -94.251502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321394942, states[0] = -94.266137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329549393, states[0] = -94.248508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337228171, states[0] = -94.254781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345365078, states[0] = -94.183218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353874845, states[0] = -94.248891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362500702, states[0] = -94.252806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370881685, states[0] = -94.280632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379653361, states[0] = -94.248215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388315008, states[0] = -94.249631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395987052, states[0] = -94.277027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405383641, states[0] = -94.202910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413994874, states[0] = -94.248466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423197620, states[0] = -94.249740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431528221, states[0] = -94.262937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440616471, states[0] = -94.282234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449115055, states[0] = -94.248183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457546086, states[0] = -94.252077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466523474, states[0] = -94.262850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475384011, states[0] = -94.202919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485109815, states[0] = 0.808825, states[40]= 0.000194
Saving checkpoint... 
Iteration: 1492836715, states[0] = -94.250548, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.123502
 - CaMKt in component CaMK (millimolar): 0.000973
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 7.065165
 - nass in component intracellular_ions (millimolar): 7.065293
 - ki in component intracellular_ions (millimolar): 144.679611
 - kss in component intracellular_ions (millimolar): 144.679600
 - cansr in component intracellular_ions (millimolar): 2.340133
 - cajsr in component intracellular_ions (millimolar): 2.340364
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003914
 - hf in component INa (dimensionless): 0.865824
 - hs in component INa (dimensionless): 0.865824
 - j in component INa (dimensionless): 0.865824
 - hsp in component INa (dimensionless): 0.699685
 - jp in component INa (dimensionless): 0.865824
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708152
 - hLp in component INaL (dimensionless): 0.514607
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.999851
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999851
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999992
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005071
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000005
 - xs1 in component IKs (dimensionless): 0.002106
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997534
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:47:01 (36413): called boinc_finish(0)

</stderr_txt>
]]>


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