𝕏

Task 55420921

Name HuVeMOp_20240630105131469782_ORdGradInc_k_25-Pueyo_APDR-conf_944_0
Workunit 26317042
Created 30 Jun 2024, 8:52:14 UTC
Sent 30 Jun 2024, 10:39:01 UTC
Report deadline 3 Jul 2024, 20:15:01 UTC
Received 30 Jun 2024, 17:15:26 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241385
Run time 1 hours 10 min 33 sec
CPU time 1 hours 8 min 37 sec
Validate state Valid
Credit 61.82
Device peak FLOPS 5.21 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.23 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630105131469782_ORdGradInc_k_25-Pueyo_APDR-conf_944.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630105131469782_ORdGradInc_k_25-Pueyo_APDR-conf_944_0_r1091738637_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630105131469782_ORdGradInc_k_25-Pueyo_APDR-conf_944_0_r1091738637_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 96.548549
     * GNaL_b in INaL: 0.007137
     * Gto_b in Ito: 0.072723
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032850
     * GKs_b in IKs: 0.002060
     * GK1_b in IK1: 0.168563
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 68.280423
     * GKb_b in IKb: 0.003775
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019856
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 19963715, states[0] = -95.072205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39919200, states[0] = -95.039426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59868423, states[0] = -95.012063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79427135, states[0] = -95.024341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99391272, states[0] = -95.011193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119404122, states[0] = -95.013287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139562994, states[0] = 7.056888, states[40]= 0.004963
Saving checkpoint... 
Iteration: 153998391, states[0] = -95.029844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166923440, states[0] = -95.016630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175830023, states[0] = -94.980652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179032098, states[0] = 19.255919, states[40]= 0.005988
Saving checkpoint... 
Iteration: 180914700, states[0] = -95.014245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183733036, states[0] = -94.885864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187124006, states[0] = -41.596393, states[40]= 0.000111
Saving checkpoint... 
Iteration: 195799711, states[0] = -94.960003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207790126, states[0] = -94.952071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214451414, states[0] = -95.022088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222720950, states[0] = -94.866028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233222049, states[0] = -94.867863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245945175, states[0] = -95.020793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258026704, states[0] = 20.949818, states[40]= 0.006820
Saving checkpoint... 
Iteration: 270763136, states[0] = -94.925222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283959002, states[0] = -95.023275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297088386, states[0] = -7.951971, states[40]= 0.002828
Saving checkpoint... 
Iteration: 310327133, states[0] = -94.978436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324103672, states[0] = -21.933777, states[40]= 0.000886
Saving checkpoint... 
Iteration: 338037903, states[0] = 17.235267, states[40]= 0.005529
Saving checkpoint... 
Iteration: 355298319, states[0] = -94.958561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375587091, states[0] = -6.907064, states[40]= 0.003060
Saving checkpoint... 
Iteration: 395490319, states[0] = -95.027863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415587985, states[0] = -7.623976, states[40]= 0.002901
Saving checkpoint... 
Iteration: 435784303, states[0] = -94.946596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456250755, states[0] = -94.910169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476637161, states[0] = -56.067956, states[40]= 0.000011
Saving checkpoint... 
Iteration: 496690049, states[0] = -94.805810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516558588, states[0] = 9.025446, states[40]= 0.005039
Saving checkpoint... 
Iteration: 536412355, states[0] = -95.013019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556470383, states[0] = -95.024940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576497650, states[0] = -95.028653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597315602, states[0] = -94.970968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617250324, states[0] = -94.909509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637475659, states[0] = -95.025685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657307305, states[0] = -94.965163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677929178, states[0] = -95.017070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697973028, states[0] = -95.025253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718537706, states[0] = 17.306937, states[40]= 0.005540
Saving checkpoint... 
Iteration: 738682542, states[0] = -94.785872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758873187, states[0] = -95.000297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779149923, states[0] = -72.810642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 799111482, states[0] = -29.318174, states[40]= 0.000531
Saving checkpoint... 
Iteration: 819202737, states[0] = -94.831872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839349544, states[0] = -94.990083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859385762, states[0] = -95.004780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879779929, states[0] = -94.942230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899780021, states[0] = -94.942304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920076658, states[0] = 0.174225, states[40]= 0.004380
Saving checkpoint... 
Iteration: 940312004, states[0] = -94.968301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960255786, states[0] = -94.916120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980155080, states[0] = -81.676275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000015372, states[0] = 23.688606, states[40]= 0.017175
Saving checkpoint... 
Iteration: 1020489802, states[0] = -95.027387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040928562, states[0] = -95.016692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061291676, states[0] = -94.952659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081262479, states[0] = -94.923916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101677944, states[0] = -94.760843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122072935, states[0] = 2.241712, states[40]= 0.004622
Saving checkpoint... 
Iteration: 1142586438, states[0] = -6.394410, states[40]= 0.003172
Saving checkpoint... 
Iteration: 1162982480, states[0] = -95.026316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182768635, states[0] = -94.930635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202784074, states[0] = -94.945883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223297865, states[0] = -94.957629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243698342, states[0] = -94.822778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263940629, states[0] = -95.019159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284027120, states[0] = 20.828287, states[40]= 0.006731
Saving checkpoint... 
Iteration: 1304068148, states[0] = 4.673397, states[40]= 0.004827
Saving checkpoint... 
Iteration: 1323814503, states[0] = -94.969755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343800836, states[0] = -94.959877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363866670, states[0] = -94.997323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384259674, states[0] = -94.920481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404564175, states[0] = 6.548331, states[40]= 0.004938
Saving checkpoint... 
Iteration: 1424737889, states[0] = -94.891936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444941532, states[0] = -95.019224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465168270, states[0] = -94.311746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485529597, states[0] = 20.071666, states[40]= 0.006302
Saving checkpoint... 
Iteration: 1505550827, states[0] = -94.778324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525665703, states[0] = -95.072996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1545675593, states[0] = -9.423713, states[40]= 0.002824
Saving checkpoint... 
Iteration: 1565550708, states[0] = -94.959276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585819278, states[0] = 22.378188, states[40]= 0.011828
Saving checkpoint... 
Iteration: 1605985830, states[0] = -20.985760, states[40]= 0.000997
Saving checkpoint... 
Iteration: 1626062024, states[0] = 1.166009, states[40]= 0.005087
Saving checkpoint... 
Iteration: 1646064841, states[0] = -95.267466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666116366, states[0] = -95.208559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686805513, states[0] = -95.190517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1706529817, states[0] = -76.208123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726668274, states[0] = -95.109601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746557067, states[0] = -95.260493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1766644394, states[0] = -95.246805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786836573, states[0] = 15.192236, states[40]= 0.006525
Saving checkpoint... 
Iteration: 1807102739, states[0] = -24.329549, states[40]= 0.000796
Saving checkpoint... 
Iteration: 1827385110, states[0] = -95.032854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848040292, states[0] = 16.109695, states[40]= 0.005412
Saving checkpoint... 
Iteration: 1868474497, states[0] = -95.033398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888824489, states[0] = -94.980564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909209967, states[0] = -94.847717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929778331, states[0] = -94.941409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950321497, states[0] = -94.974639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970193372, states[0] = -94.812394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990310051, states[0] = -94.966438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010354152, states[0] = -94.991556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030559564, states[0] = 8.602492, states[40]= 0.005025
Saving checkpoint... 
Iteration: 2050323301, states[0] = -94.974943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070388388, states[0] = -95.004834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090262045, states[0] = -94.922711, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.903760
 - CaMKt in component CaMK (millimolar): 0.007144
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.661923
 - nass in component intracellular_ions (millimolar): 6.661984
 - ki in component intracellular_ions (millimolar): 145.312099
 - kss in component intracellular_ions (millimolar): 145.312080
 - cansr in component intracellular_ions (millimolar): 1.327772
 - cajsr in component intracellular_ions (millimolar): 1.289631
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003618
 - hf in component INa (dimensionless): 0.880034
 - hs in component INa (dimensionless): 0.880029
 - j in component INa (dimensionless): 0.880000
 - hsp in component INa (dimensionless): 0.725892
 - jp in component INa (dimensionless): 0.879981
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710034
 - hLp in component INaL (dimensionless): 0.452303
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620696
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695021
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931552
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999876
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001676
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.338325
 - xs1 in component IKs (dimensionless): 0.245574
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:10:05 (18300): called boinc_finish(0)

</stderr_txt>
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