𝕏

Task 55419894

Name HuVeMOp_20240630105043357026_ORdGradInc_k_25-Pueyo_APDR-conf_999_1
Workunit 26316529
Created 30 Jun 2024, 8:51:32 UTC
Sent 30 Jun 2024, 10:29:34 UTC
Report deadline 3 Jul 2024, 20:05:34 UTC
Received 30 Jun 2024, 17:43:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227663
Run time 2 hours 32 min
CPU time 1 hours 51 min 59 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 2.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.85 MB
Peak swap size 32.57 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630105043357026_ORdGradInc_k_25-Pueyo_APDR-conf_999.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630105043357026_ORdGradInc_k_25-Pueyo_APDR-conf_999_1_r981014993_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630105043357026_ORdGradInc_k_25-Pueyo_APDR-conf_999_1_r981014993_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.111600
     * GNaL_b in INaL: 0.004676
     * Gto_b in Ito: 0.082307
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031812
     * GKs_b in IKs: 0.001910
     * GK1_b in IK1: 0.166267
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 68.919121
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048047
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 22828082, states[0] = -95.049631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38521919, states[0] = 20.194404, states[40]= 0.008421
Saving checkpoint... 
Iteration: 61884066, states[0] = -95.034145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84078519, states[0] = -3.573572, states[40]= 0.003671
Saving checkpoint... 
Iteration: 99246841, states[0] = -94.933014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128313243, states[0] = -94.988668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144993084, states[0] = -95.040882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159372824, states[0] = -95.015291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176662511, states[0] = -93.862901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190441698, states[0] = -95.032373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204435770, states[0] = -95.031125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210081471, states[0] = -5.376631, states[40]= 0.003308
Saving checkpoint... 
Iteration: 221107761, states[0] = -30.006133, states[40]= 0.000437
Saving checkpoint... 
Iteration: 235803357, states[0] = -94.979947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251425426, states[0] = -95.028812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266573539, states[0] = -0.137644, states[40]= 0.004218
Saving checkpoint... 
Iteration: 283764692, states[0] = -94.947397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300686671, states[0] = -94.828177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318812809, states[0] = -94.985981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332938678, states[0] = -95.031354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346566767, states[0] = 3.474694, states[40]= 0.004599
Saving checkpoint... 
Iteration: 363627251, states[0] = -49.921686, states[40]= 0.000026
Saving checkpoint... 
Iteration: 382144593, states[0] = -70.524092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401029148, states[0] = 18.512891, states[40]= 0.006288
Saving checkpoint... 
Iteration: 419471655, states[0] = -95.036628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437274583, states[0] = -94.956837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455115456, states[0] = -37.632417, states[40]= 0.000169
Saving checkpoint... 
Iteration: 473688952, states[0] = -94.832876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491081488, states[0] = -5.380093, states[40]= 0.003307
Saving checkpoint... 
Iteration: 508543060, states[0] = 13.586130, states[40]= 0.005151
Saving checkpoint... 
Iteration: 527122618, states[0] = -44.982626, states[40]= 0.000057
Saving checkpoint... 
Iteration: 544720092, states[0] = -94.889731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566214120, states[0] = -94.879912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589479666, states[0] = -95.037590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614692639, states[0] = -94.840282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640739200, states[0] = -94.917511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663774811, states[0] = -94.956909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681723615, states[0] = -94.895181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700077814, states[0] = -2.784551, states[40]= 0.003807
Saving checkpoint... 
Iteration: 718128513, states[0] = -51.288304, states[40]= 0.000021
Saving checkpoint... 
Iteration: 737064116, states[0] = 4.753507, states[40]= 0.004691
Saving checkpoint... 
Iteration: 759747307, states[0] = -94.927724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785128249, states[0] = -51.001542, states[40]= 0.000022
Saving checkpoint... 
Iteration: 809454829, states[0] = -95.033879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835075530, states[0] = -1.325686, states[40]= 0.004047
Saving checkpoint... 
Iteration: 858657496, states[0] = -90.833822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883908360, states[0] = -95.024435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907630132, states[0] = -53.054979, states[40]= 0.000015
Saving checkpoint... 
Iteration: 932138821, states[0] = -62.959475, states[40]= 0.000003
Saving checkpoint... 
Iteration: 947625267, states[0] = -47.789864, states[40]= 0.000036
Saving checkpoint... 
Iteration: 965255931, states[0] = -94.937639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983242524, states[0] = -94.921625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001451950, states[0] = -95.033292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019804399, states[0] = -94.980082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042062841, states[0] = 5.348400, states[40]= 0.004727
Saving checkpoint... 
Iteration: 1067451294, states[0] = -95.033143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092294710, states[0] = -94.973139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117167756, states[0] = -94.610912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140525396, states[0] = 19.616687, states[40]= 0.007098
Saving checkpoint... 
Iteration: 1165686952, states[0] = -94.828241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186409462, states[0] = -95.024527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204856795, states[0] = -95.007699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223408853, states[0] = -95.024354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246607494, states[0] = -29.732442, states[40]= 0.000450
Saving checkpoint... 
Iteration: 1271775127, states[0] = -94.956832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295774439, states[0] = -94.956187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318880656, states[0] = -95.016289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338472456, states[0] = -95.036186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357065715, states[0] = 3.989750, states[40]= 0.004638
Saving checkpoint... 
Iteration: 1377162602, states[0] = -93.874311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402976055, states[0] = -95.036632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425409762, states[0] = -95.024457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443259377, states[0] = -94.941118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463379431, states[0] = -95.015804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483082545, states[0] = -6.188938, states[40]= 0.003138
Saving checkpoint... 
Iteration: 1504529872, states[0] = 17.491294, states[40]= 0.007256
Saving checkpoint... 
Iteration: 1523035906, states[0] = -95.226164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541486000, states[0] = -24.178070, states[40]= 0.000734
Saving checkpoint... 
Iteration: 1559025850, states[0] = -95.236030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577997380, states[0] = -95.305748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595199510, states[0] = -40.389148, states[40]= 0.000118
Saving checkpoint... 
Iteration: 1614422387, states[0] = -69.561906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1638816813, states[0] = -95.233851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664692474, states[0] = -95.308317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686170354, states[0] = -95.146937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703833067, states[0] = -88.417782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720635135, states[0] = -91.095285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737743973, states[0] = -94.824009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756473288, states[0] = -95.295176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775873721, states[0] = -95.154930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796176309, states[0] = -14.279353, states[40]= 0.001769
Saving checkpoint... 
Iteration: 1822192114, states[0] = -94.872267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844006993, states[0] = 24.839069, states[40]= 0.103001
Saving checkpoint... 
Iteration: 1864681670, states[0] = -94.825987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882778047, states[0] = -94.965086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901382316, states[0] = -95.019895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919529105, states[0] = 18.501698, states[40]= 0.006293
Saving checkpoint... 
Iteration: 1936838011, states[0] = -95.000099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955661183, states[0] = -93.407149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1974317903, states[0] = -94.988441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998838879, states[0] = -94.999441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023763136, states[0] = -94.944776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047663664, states[0] = -94.130215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064568265, states[0] = 2.723159, states[40]= 0.004535
Saving checkpoint... 
Iteration: 2080261216, states[0] = -94.942656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098552856, states[0] = 9.684766, states[40]= 0.004922
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.914881
 - CaMKt in component CaMK (millimolar): 0.006729
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.596382
 - nass in component intracellular_ions (millimolar): 6.596440
 - ki in component intracellular_ions (millimolar): 145.385122
 - kss in component intracellular_ions (millimolar): 145.385103
 - cansr in component intracellular_ions (millimolar): 1.295253
 - cajsr in component intracellular_ions (millimolar): 1.257856
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003614
 - hf in component INa (dimensionless): 0.880227
 - hs in component INa (dimensionless): 0.880222
 - j in component INa (dimensionless): 0.880196
 - hsp in component INa (dimensionless): 0.726259
 - jp in component INa (dimensionless): 0.880179
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711219
 - hLp in component INaL (dimensionless): 0.455266
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.625378
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.701133
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938126
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999896
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001532
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.323353
 - xs1 in component IKs (dimensionless): 0.235045
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997334
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:02:34 (40129): called boinc_finish(0)

</stderr_txt>
]]>


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