𝕏

Task 55418236

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_783_2
Workunit 26230263
Created 30 Jun 2024, 8:17:59 UTC
Sent 30 Jun 2024, 10:14:07 UTC
Report deadline 3 Jul 2024, 19:50:07 UTC
Received 1 Jul 2024, 21:25:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241235
Run time 2 hours 11 min 49 sec
CPU time 2 hours 9 min 54 sec
Validate state Valid
Credit 61.82
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.84 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.16.6</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_783.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_783_2_r1644603342_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_783_2_r1644603342_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.579844
     * GNaL_b in INaL: 0.006712
     * Gto_b in Ito: 0.074316
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031184
     * GKs_b in IKs: 0.001970
     * GK1_b in IK1: 0.173730
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 71.869043
     * GKb_b in IKb: 0.003743
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048863
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16687022, states[0] = -94.990233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33278075, states[0] = -95.075180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49814323, states[0] = -95.082574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66187969, states[0] = -94.925571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82813337, states[0] = -95.065728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99504815, states[0] = 30.852263, states[40]= 0.135701
Saving checkpoint... 
Iteration: 116188047, states[0] = -94.913405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132691477, states[0] = -94.918838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149066611, states[0] = 5.722352, states[40]= 0.004788
Saving checkpoint... 
Iteration: 165890470, states[0] = -95.088966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182654819, states[0] = -77.949505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199373674, states[0] = -95.083345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215793803, states[0] = -95.043662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232532747, states[0] = 18.958938, states[40]= 0.006063
Saving checkpoint... 
Iteration: 249042701, states[0] = 15.435529, states[40]= 0.005323
Saving checkpoint... 
Iteration: 265518341, states[0] = 22.912392, states[40]= 0.012293
Saving checkpoint... 
Iteration: 282197279, states[0] = -94.927239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298747967, states[0] = -95.001541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315563340, states[0] = 7.204052, states[40]= 0.004869
Saving checkpoint... 
Iteration: 332178319, states[0] = -94.868645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348663323, states[0] = -91.589408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365418279, states[0] = -95.094910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382317851, states[0] = -95.058700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399052096, states[0] = 11.829139, states[40]= 0.005066
Saving checkpoint... 
Iteration: 415896567, states[0] = -95.089684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432594981, states[0] = -12.310537, states[40]= 0.001875
Saving checkpoint... 
Iteration: 448994372, states[0] = -95.106629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465442183, states[0] = -95.099483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482146762, states[0] = -65.359986, states[40]= 0.000002
Saving checkpoint... 
Iteration: 498568145, states[0] = 5.055670, states[40]= 0.004743
Saving checkpoint... 
Iteration: 515137472, states[0] = -54.073680, states[40]= 0.000014
Saving checkpoint... 
Iteration: 531728832, states[0] = -94.977240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548269600, states[0] = -95.023623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564894876, states[0] = -95.089154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581391675, states[0] = -95.088272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597965054, states[0] = -95.102973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614626874, states[0] = -42.551406, states[40]= 0.000088
Saving checkpoint... 
Iteration: 631364358, states[0] = -95.079617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647992163, states[0] = -95.106287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664578236, states[0] = -0.073792, states[40]= 0.004232
Saving checkpoint... 
Iteration: 681117341, states[0] = -33.166318, states[40]= 0.000328
Saving checkpoint... 
Iteration: 697541360, states[0] = 15.934078, states[40]= 0.005384
Saving checkpoint... 
Iteration: 714010345, states[0] = 24.760207, states[40]= 0.048332
Saving checkpoint... 
Iteration: 730738650, states[0] = -94.990103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747251724, states[0] = -95.005509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763772457, states[0] = -95.026093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780353344, states[0] = -95.075373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796889808, states[0] = -95.087637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813471858, states[0] = -95.103780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829961021, states[0] = -95.102277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846658788, states[0] = -85.221577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863176686, states[0] = -94.847547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879762194, states[0] = -95.016385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896274844, states[0] = -95.028124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912786345, states[0] = -95.037551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929376957, states[0] = -95.083717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946397084, states[0] = -95.089540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963508586, states[0] = 25.587698, states[40]= 0.071128
Saving checkpoint... 
Iteration: 980464723, states[0] = -95.102725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997598170, states[0] = -15.210943, states[40]= 0.001427
Saving checkpoint... 
Iteration: 1014693966, states[0] = -94.920835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031695982, states[0] = -94.924490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048678756, states[0] = -94.872366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065546270, states[0] = 14.089066, states[40]= 0.005197
Saving checkpoint... 
Iteration: 1082423354, states[0] = -95.095600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099118119, states[0] = -33.908929, states[40]= 0.000298
Saving checkpoint... 
Iteration: 1116157702, states[0] = -83.232000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132966238, states[0] = -95.102855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149948762, states[0] = -95.100224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167131144, states[0] = -47.051229, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1184190555, states[0] = -94.914325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201145735, states[0] = -64.008763, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1218113798, states[0] = -29.809179, states[40]= 0.000478
Saving checkpoint... 
Iteration: 1235090426, states[0] = -8.404420, states[40]= 0.002650
Saving checkpoint... 
Iteration: 1252166930, states[0] = -93.782152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269071658, states[0] = 3.384465, states[40]= 0.004614
Saving checkpoint... 
Iteration: 1286112504, states[0] = -28.591088, states[40]= 0.000538
Saving checkpoint... 
Iteration: 1302823612, states[0] = -95.061366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319714538, states[0] = -94.955669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336548832, states[0] = 13.103857, states[40]= 0.005131
Saving checkpoint... 
Iteration: 1353321387, states[0] = -95.060142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370210063, states[0] = -94.948467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387117903, states[0] = -33.702304, states[40]= 0.000306
Saving checkpoint... 
Iteration: 1404106802, states[0] = -23.254455, states[40]= 0.000791
Saving checkpoint... 
Iteration: 1421122876, states[0] = -38.523867, states[40]= 0.000159
Saving checkpoint... 
Iteration: 1438133915, states[0] = -50.078568, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1455105780, states[0] = -22.300487, states[40]= 0.000837
Saving checkpoint... 
Iteration: 1472097330, states[0] = -14.438223, states[40]= 0.001533
Saving checkpoint... 
Iteration: 1489175048, states[0] = -94.813167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506213588, states[0] = -95.241811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523117609, states[0] = 23.133556, states[40]= 0.015029
Saving checkpoint... 
Iteration: 1540047225, states[0] = -94.613616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557113482, states[0] = -49.855960, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1574103634, states[0] = 36.354910, states[40]= 0.108674
Saving checkpoint... 
Iteration: 1591184713, states[0] = -95.352581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608160972, states[0] = -95.181198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625099260, states[0] = -95.363664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641817359, states[0] = -95.290593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658512969, states[0] = -50.000764, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1675278250, states[0] = -11.788511, states[40]= 0.002240
Saving checkpoint... 
Iteration: 1692173613, states[0] = -95.214774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709070253, states[0] = -95.345713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725945575, states[0] = 10.817938, states[40]= 0.005920
Saving checkpoint... 
Iteration: 1742696463, states[0] = -95.363121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759443223, states[0] = -95.321826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776408126, states[0] = -44.198719, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1793191699, states[0] = -26.128623, states[40]= 0.000655
Saving checkpoint... 
Iteration: 1809969834, states[0] = -95.145613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826839245, states[0] = -95.096129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843726847, states[0] = -94.990766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860664724, states[0] = -93.228188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877634346, states[0] = -51.104997, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1894497292, states[0] = -95.109841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911403564, states[0] = -95.092897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928176499, states[0] = -94.847013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945203832, states[0] = -94.938561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962268063, states[0] = -95.021918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979262295, states[0] = -95.016167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996128531, states[0] = -44.287157, states[40]= 0.000068
Saving checkpoint... 
Iteration: 2012942673, states[0] = -95.098817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029729235, states[0] = -94.977025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046591845, states[0] = -9.583633, states[40]= 0.002402
Saving checkpoint... 
Iteration: 2063560582, states[0] = 8.381842, states[40]= 0.004924
Saving checkpoint... 
Iteration: 2080430924, states[0] = -95.096547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097249590, states[0] = -95.002377, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.982175
 - CaMKt in component CaMK (millimolar): 0.006677
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.514473
 - nass in component intracellular_ions (millimolar): 6.514530
 - ki in component intracellular_ions (millimolar): 145.469090
 - kss in component intracellular_ions (millimolar): 145.469071
 - cansr in component intracellular_ions (millimolar): 1.289429
 - cajsr in component intracellular_ions (millimolar): 1.251534
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003589
 - hf in component INa (dimensionless): 0.881388
 - hs in component INa (dimensionless): 0.881384
 - j in component INa (dimensionless): 0.881359
 - hsp in component INa (dimensionless): 0.728453
 - jp in component INa (dimensionless): 0.881342
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711732
 - hLp in component INaL (dimensionless): 0.453494
 - a in component Ito (dimensionless): 0.000620
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.619233
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.693387
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930812
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999871
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001519
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.340943
 - xs1 in component IKs (dimensionless): 0.248558
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997316
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:25:10 (922909): called boinc_finish(0)

</stderr_txt>
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