𝕏

Task 55417922

Name HuVeMOp_20240630101147606520_ORdGradInc_k_25-Pueyo_APDR-conf_878_1
Workunit 26315628
Created 30 Jun 2024, 8:13:02 UTC
Sent 30 Jun 2024, 10:13:28 UTC
Report deadline 3 Jul 2024, 19:49:28 UTC
Received 2 Jul 2024, 19:50:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240905
Run time 7 hours 43 min 7 sec
CPU time 7 hours 40 min 54 sec
Validate state Valid
Credit 58.46
Device peak FLOPS 1.07 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.75 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101147606520_ORdGradInc_k_25-Pueyo_APDR-conf_878.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101147606520_ORdGradInc_k_25-Pueyo_APDR-conf_878_1_r1964101830_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101147606520_ORdGradInc_k_25-Pueyo_APDR-conf_878_1_r1964101830_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.805176
     * GNaL_b in INaL: 0.005263
     * Gto_b in Ito: 0.080882
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032578
     * GKs_b in IKs: 0.002054
     * GK1_b in IK1: 0.165059
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 72.033436
     * GKb_b in IKb: 0.003682
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045452
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12686989, states[0] = -94.873929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26578485, states[0] = -6.046078, states[40]= 0.003230
Saving checkpoint... 
Iteration: 40456685, states[0] = -95.011976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54340282, states[0] = -94.966923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68225540, states[0] = -94.858447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82120122, states[0] = -44.945718, states[40]= 0.000056
Saving checkpoint... 
Iteration: 95998380, states[0] = -94.988932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109889415, states[0] = -94.966833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123782315, states[0] = -94.910420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137667081, states[0] = -94.627493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151565771, states[0] = 3.521377, states[40]= 0.004663
Saving checkpoint... 
Iteration: 165459411, states[0] = -94.978413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179356811, states[0] = -94.951944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193223777, states[0] = -94.840966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206611055, states[0] = -34.874687, states[40]= 0.000241
Saving checkpoint... 
Iteration: 218554265, states[0] = 8.842575, states[40]= 0.004983
Saving checkpoint... 
Iteration: 232406742, states[0] = -94.967362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246298823, states[0] = -94.920315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260183201, states[0] = -94.767190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274058137, states[0] = 7.149633, states[40]= 0.004898
Saving checkpoint... 
Iteration: 287946481, states[0] = -94.975489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301834153, states[0] = -94.941250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315732506, states[0] = -94.853230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329604626, states[0] = -28.395363, states[40]= 0.000501
Saving checkpoint... 
Iteration: 343505473, states[0] = 28.300067, states[40]= 0.129676
Saving checkpoint... 
Iteration: 357396195, states[0] = -94.964432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371244663, states[0] = -94.869106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385130638, states[0] = -55.892157, states[40]= 0.000009
Saving checkpoint... 
Iteration: 399013045, states[0] = 22.644624, states[40]= 0.028409
Saving checkpoint... 
Iteration: 412895361, states[0] = -94.964171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419621637, states[0] = -45.894305, states[40]= 0.000048
Saving checkpoint... 
Iteration: 428894961, states[0] = -94.964051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438283203, states[0] = -94.908191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447494110, states[0] = -94.981938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456705328, states[0] = -94.810018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466156110, states[0] = -91.506025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479836017, states[0] = -94.942060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493713779, states[0] = -94.824564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507592615, states[0] = -16.394680, states[40]= 0.001292
Saving checkpoint... 
Iteration: 521455302, states[0] = -94.976792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535331334, states[0] = -94.939690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549208426, states[0] = -94.815427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563053753, states[0] = 9.065216, states[40]= 0.004993
Saving checkpoint... 
Iteration: 576917909, states[0] = -94.969705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590804214, states[0] = -94.923763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604668830, states[0] = -94.672862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618525596, states[0] = 19.608018, states[40]= 0.007474
Saving checkpoint... 
Iteration: 632391106, states[0] = -94.962852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646250634, states[0] = -94.876079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660127291, states[0] = -52.118342, states[40]= 0.000018
Saving checkpoint... 
Iteration: 674017825, states[0] = 21.591008, states[40]= 0.013262
Saving checkpoint... 
Iteration: 687911797, states[0] = -94.968238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701791642, states[0] = -94.914740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715695892, states[0] = -94.792449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729567389, states[0] = 2.726967, states[40]= 0.004592
Saving checkpoint... 
Iteration: 743442041, states[0] = -94.974450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757342304, states[0] = -94.944890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771234984, states[0] = -94.856381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785120862, states[0] = -45.057636, states[40]= 0.000055
Saving checkpoint... 
Iteration: 798996381, states[0] = -94.981995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812865666, states[0] = -94.954468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826754952, states[0] = -94.880867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840612464, states[0] = -36.288966, states[40]= 0.000199
Saving checkpoint... 
Iteration: 854489776, states[0] = -94.981241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868364817, states[0] = -94.954125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882238763, states[0] = -94.861352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896120575, states[0] = -44.749017, states[40]= 0.000057
Saving checkpoint... 
Iteration: 910000781, states[0] = 46.572007, states[40]= 0.009974
Saving checkpoint... 
Iteration: 923872819, states[0] = -94.956945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937744102, states[0] = -94.868109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951610727, states[0] = -34.527305, states[40]= 0.000252
Saving checkpoint... 
Iteration: 965474483, states[0] = -94.979316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979326750, states[0] = -94.937057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993203867, states[0] = -94.807109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007049690, states[0] = 10.773914, states[40]= 0.005085
Saving checkpoint... 
Iteration: 1020932373, states[0] = -94.972496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034814933, states[0] = -94.930325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048688495, states[0] = -94.777800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062568206, states[0] = 2.300090, states[40]= 0.004551
Saving checkpoint... 
Iteration: 1076442325, states[0] = -94.974323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090309132, states[0] = -94.926706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104186725, states[0] = -94.774172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118070759, states[0] = 0.912760, states[40]= 0.004399
Saving checkpoint... 
Iteration: 1131957903, states[0] = -94.976871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145840100, states[0] = -94.943660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159708916, states[0] = -94.815951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173605889, states[0] = -29.659984, states[40]= 0.000444
Saving checkpoint... 
Iteration: 1187492054, states[0] = -94.981319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201376220, states[0] = -94.957943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215249694, states[0] = -94.874682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229116295, states[0] = -40.226177, states[40]= 0.000114
Saving checkpoint... 
Iteration: 1242994342, states[0] = -94.981540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256858796, states[0] = -94.951626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270718474, states[0] = -94.831789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284598007, states[0] = -21.775399, states[40]= 0.000831
Saving checkpoint... 
Iteration: 1298478942, states[0] = -94.979712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312361526, states[0] = -94.952652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326237771, states[0] = -94.859812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340116189, states[0] = -40.115915, states[40]= 0.000115
Saving checkpoint... 
Iteration: 1353977693, states[0] = -94.979524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367860679, states[0] = -94.952298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381734350, states[0] = -94.855191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395612247, states[0] = -36.067942, states[40]= 0.000205
Saving checkpoint... 
Iteration: 1409507549, states[0] = 25.155081, states[40]= 0.091816
Saving checkpoint... 
Iteration: 1423388296, states[0] = -94.961610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437261221, states[0] = -94.887256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451147988, states[0] = -79.486995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464990084, states[0] = -94.980951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478876170, states[0] = -94.957779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492750454, states[0] = -94.875418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506604260, states[0] = 33.550877, states[40]= 0.098697
Saving checkpoint... 
Iteration: 1520467950, states[0] = -4.956037, states[40]= 0.003811
Saving checkpoint... 
Iteration: 1534322835, states[0] = -70.572276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1548181172, states[0] = -95.106908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562025783, states[0] = -95.186592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575845912, states[0] = -95.213371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589678342, states[0] = -95.243733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603537598, states[0] = 13.187434, states[40]= 0.006424
Saving checkpoint... 
Iteration: 1617358244, states[0] = 1.397070, states[40]= 0.005011
Saving checkpoint... 
Iteration: 1631189706, states[0] = -30.520542, states[40]= 0.000407
Saving checkpoint... 
Iteration: 1645012674, states[0] = -58.226905, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1658848951, states[0] = -95.012686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672686421, states[0] = -95.132801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686540399, states[0] = -95.213534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700382985, states[0] = -95.250768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714210438, states[0] = 24.168545, states[40]= 0.049353
Saving checkpoint... 
Iteration: 1728040241, states[0] = 11.811970, states[40]= 0.006196
Saving checkpoint... 
Iteration: 1741873028, states[0] = -11.540560, states[40]= 0.002311
Saving checkpoint... 
Iteration: 1755719640, states[0] = -67.821387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1769556947, states[0] = -95.063668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1781917126, states[0] = -95.184625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794164864, states[0] = -95.085478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807986224, states[0] = -95.030899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821818864, states[0] = -94.967426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835664347, states[0] = -94.596913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848756672, states[0] = -94.898387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862607760, states[0] = -32.200514, states[40]= 0.000335
Saving checkpoint... 
Iteration: 1876446172, states[0] = -94.981464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890278546, states[0] = -94.908070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904108734, states[0] = -32.709178, states[40]= 0.000316
Saving checkpoint... 
Iteration: 1917943241, states[0] = -94.975999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931777518, states[0] = -94.903851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945608422, states[0] = -32.258454, states[40]= 0.000333
Saving checkpoint... 
Iteration: 1959453704, states[0] = -94.976311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973294585, states[0] = -94.916608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987100292, states[0] = -24.074693, states[40]= 0.000707
Saving checkpoint... 
Iteration: 2000919477, states[0] = -94.969421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014750954, states[0] = -94.875787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028564507, states[0] = 4.176359, states[40]= 0.004714
Saving checkpoint... 
Iteration: 2042388302, states[0] = -94.961288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056198473, states[0] = -94.796601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070020144, states[0] = 21.055771, states[40]= 0.010431
Saving checkpoint... 
Iteration: 2083861972, states[0] = -94.952382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097684129, states[0] = -94.768148, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.857521
 - CaMKt in component CaMK (millimolar): 0.006521
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.563816
 - nass in component intracellular_ions (millimolar): 6.563873
 - ki in component intracellular_ions (millimolar): 145.420669
 - kss in component intracellular_ions (millimolar): 145.420651
 - cansr in component intracellular_ions (millimolar): 1.284906
 - cajsr in component intracellular_ions (millimolar): 1.247928
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.003635
 - hf in component INa (dimensionless): 0.879229
 - hs in component INa (dimensionless): 0.879225
 - j in component INa (dimensionless): 0.879200
 - hsp in component INa (dimensionless): 0.724381
 - jp in component INa (dimensionless): 0.879182
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710232
 - hLp in component INaL (dimensionless): 0.455172
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.627110
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.702975
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938685
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999898
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001499
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331826
 - xs1 in component IKs (dimensionless): 0.232640
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997349
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:47:50 (31686): called boinc_finish(0)

</stderr_txt>
]]>


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