𝕏

Task 55417750

Name HuVeMOp_20240630101147606520_ORdGradInc_k_25-Pueyo_APDR-conf_861_1
Workunit 26315542
Created 30 Jun 2024, 8:12:57 UTC
Sent 30 Jun 2024, 10:08:52 UTC
Report deadline 3 Jul 2024, 19:44:52 UTC
Received 3 Jul 2024, 18:06:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227058
Run time 2 hours 32 min 7 sec
CPU time 2 hours 30 min 28 sec
Validate state Valid
Credit 58.23
Device peak FLOPS 4.67 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101147606520_ORdGradInc_k_25-Pueyo_APDR-conf_861.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101147606520_ORdGradInc_k_25-Pueyo_APDR-conf_861_1_r1452500021_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101147606520_ORdGradInc_k_25-Pueyo_APDR-conf_861_1_r1452500021_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.056598
     * GNaL_b in INaL: 0.005823
     * Gto_b in Ito: 0.085541
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031055
     * GKs_b in IKs: 0.001803
     * GK1_b in IK1: 0.148691
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 70.274706
     * GKb_b in IKb: 0.003847
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050726
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15661121, states[0] = -89.458861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30479838, states[0] = -94.841144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45465889, states[0] = -94.820586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60180225, states[0] = -94.475463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74619166, states[0] = -36.169768, states[40]= 0.000216
Saving checkpoint... 
Iteration: 90026520, states[0] = 19.618673, states[40]= 0.006661
Saving checkpoint... 
Iteration: 104762621, states[0] = -94.691371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119330771, states[0] = -94.748497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135308521, states[0] = -94.732283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151178992, states[0] = -94.369699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166600871, states[0] = -18.699821, states[40]= 0.001047
Saving checkpoint... 
Iteration: 180706314, states[0] = -94.597037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195819378, states[0] = -94.738261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210318565, states[0] = -94.737584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224624693, states[0] = -40.782328, states[40]= 0.000112
Saving checkpoint... 
Iteration: 240404541, states[0] = -94.776749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255673737, states[0] = -93.771687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270915418, states[0] = -94.779700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285937350, states[0] = -94.784893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300333458, states[0] = -94.746711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316583584, states[0] = -4.165168, states[40]= 0.003487
Saving checkpoint... 
Iteration: 331586527, states[0] = -6.259190, states[40]= 0.003065
Saving checkpoint... 
Iteration: 345783062, states[0] = -94.708276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361180805, states[0] = -94.438524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377105411, states[0] = -22.842644, states[40]= 0.000799
Saving checkpoint... 
Iteration: 392242588, states[0] = -94.659338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408668737, states[0] = -91.733241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423332334, states[0] = -94.745960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438267254, states[0] = -94.691483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453071422, states[0] = 2.773664, states[40]= 0.004465
Saving checkpoint... 
Iteration: 467926870, states[0] = -94.782403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482674678, states[0] = -93.944833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498179317, states[0] = -94.380146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513586993, states[0] = -6.608595, states[40]= 0.002991
Saving checkpoint... 
Iteration: 529175376, states[0] = -94.048907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543306913, states[0] = -94.728769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557902254, states[0] = -94.775788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573884256, states[0] = -94.769901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588961189, states[0] = -94.789236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604390252, states[0] = -94.771955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620123648, states[0] = -39.770813, states[40]= 0.000130
Saving checkpoint... 
Iteration: 635297835, states[0] = -94.721452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650150950, states[0] = -68.310020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 664757465, states[0] = -94.679530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679904321, states[0] = -94.776326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695043382, states[0] = 14.232423, states[40]= 0.005050
Saving checkpoint... 
Iteration: 709842344, states[0] = -94.751417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724222228, states[0] = -94.626103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738460395, states[0] = -94.789009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752744978, states[0] = -94.662594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768583096, states[0] = -3.836178, states[40]= 0.003549
Saving checkpoint... 
Iteration: 783815017, states[0] = -94.734561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798162696, states[0] = -85.048462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814882974, states[0] = -94.769295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829856369, states[0] = -94.758356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844409214, states[0] = -94.777627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859565548, states[0] = 5.492296, states[40]= 0.004658
Saving checkpoint... 
Iteration: 874218997, states[0] = -94.620210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888881307, states[0] = -94.768644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904267005, states[0] = -94.690910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919969603, states[0] = -94.790405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935461782, states[0] = -94.789125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950007306, states[0] = 24.361447, states[40]= 0.096306
Saving checkpoint... 
Iteration: 964890508, states[0] = -94.771820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979808560, states[0] = -94.729748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994998842, states[0] = -94.794335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010967807, states[0] = -94.790066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025578230, states[0] = -0.821523, states[40]= 0.004052
Saving checkpoint... 
Iteration: 1040585073, states[0] = -5.199541, states[40]= 0.003283
Saving checkpoint... 
Iteration: 1056668942, states[0] = -91.868261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072282958, states[0] = -94.707725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086928370, states[0] = -94.782376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102281712, states[0] = -94.706483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116624485, states[0] = -40.573754, states[40]= 0.000115
Saving checkpoint... 
Iteration: 1130751009, states[0] = -94.670780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144872966, states[0] = -94.765309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160111413, states[0] = -28.358379, states[40]= 0.000541
Saving checkpoint... 
Iteration: 1174478456, states[0] = -94.791577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190153395, states[0] = -71.393226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1205392712, states[0] = -94.772403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220664061, states[0] = -86.971112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235840199, states[0] = -94.749935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249994793, states[0] = -94.793695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265373643, states[0] = -94.765503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280032182, states[0] = 18.052892, states[40]= 0.005758
Saving checkpoint... 
Iteration: 1295150921, states[0] = -68.273925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1309327484, states[0] = -94.742479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323357544, states[0] = -94.758599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338204961, states[0] = -94.593080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352975716, states[0] = -94.791069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367995578, states[0] = -94.793718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383075772, states[0] = 0.546550, states[40]= 0.004233
Saving checkpoint... 
Iteration: 1399816650, states[0] = -94.735323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414616125, states[0] = -32.707702, states[40]= 0.000340
Saving checkpoint... 
Iteration: 1429302422, states[0] = -94.724718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444029167, states[0] = 18.957366, states[40]= 0.006158
Saving checkpoint... 
Iteration: 1459452122, states[0] = -94.787095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475052517, states[0] = 10.817663, states[40]= 0.004865
Saving checkpoint... 
Iteration: 1491359449, states[0] = -94.759366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506140047, states[0] = -81.973855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521448901, states[0] = -93.288771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536384321, states[0] = -18.304164, states[40]= 0.001191
Saving checkpoint... 
Iteration: 1553168185, states[0] = -3.227017, states[40]= 0.004138
Saving checkpoint... 
Iteration: 1567586954, states[0] = -21.825268, states[40]= 0.000894
Saving checkpoint... 
Iteration: 1582207652, states[0] = 25.147489, states[40]= 0.085229
Saving checkpoint... 
Iteration: 1598427570, states[0] = 18.218758, states[40]= 0.007476
Saving checkpoint... 
Iteration: 1613068449, states[0] = -95.082937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628197491, states[0] = -33.376374, states[40]= 0.000311
Saving checkpoint... 
Iteration: 1643679262, states[0] = -95.093857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660365380, states[0] = -94.900499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675963721, states[0] = -94.892024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690721983, states[0] = -95.027869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1706036959, states[0] = -95.049607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722007624, states[0] = 25.142111, states[40]= 0.085821
Saving checkpoint... 
Iteration: 1737739696, states[0] = -86.976987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752163154, states[0] = -94.888757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1766081493, states[0] = -95.096378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1781211031, states[0] = -48.303088, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1797394516, states[0] = -30.277585, states[40]= 0.000441
Saving checkpoint... 
Iteration: 1812968797, states[0] = -94.842226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827783439, states[0] = -94.742933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842795815, states[0] = -94.741735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858512913, states[0] = 22.263529, states[40]= 0.027276
Saving checkpoint... 
Iteration: 1873561373, states[0] = 7.129889, states[40]= 0.004744
Saving checkpoint... 
Iteration: 1889050312, states[0] = 11.581002, states[40]= 0.004897
Saving checkpoint... 
Iteration: 1903355787, states[0] = -94.761085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918072086, states[0] = 2.396770, states[40]= 0.004433
Saving checkpoint... 
Iteration: 1933553551, states[0] = 10.396449, states[40]= 0.004852
Saving checkpoint... 
Iteration: 1948074154, states[0] = 1.379093, states[40]= 0.004329
Saving checkpoint... 
Iteration: 1963956965, states[0] = -94.788220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979582055, states[0] = -3.163230, states[40]= 0.003673
Saving checkpoint... 
Iteration: 1993673885, states[0] = -93.803057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008975618, states[0] = -94.790759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024407884, states[0] = -94.776578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038745011, states[0] = -94.661862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053895243, states[0] = -94.772691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069253761, states[0] = -94.673850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084518854, states[0] = 21.403709, states[40]= 0.010828
Saving checkpoint... 
Iteration: 2098759687, states[0] = -94.681391, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.669626
 - CaMKt in component CaMK (millimolar): 0.006829
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.625155
 - nass in component intracellular_ions (millimolar): 6.625212
 - ki in component intracellular_ions (millimolar): 145.356439
 - kss in component intracellular_ions (millimolar): 145.356421
 - cansr in component intracellular_ions (millimolar): 1.294871
 - cajsr in component intracellular_ions (millimolar): 1.256813
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003704
 - hf in component INa (dimensionless): 0.875913
 - hs in component INa (dimensionless): 0.875908
 - j in component INa (dimensionless): 0.875878
 - hsp in component INa (dimensionless): 0.718172
 - jp in component INa (dimensionless): 0.875857
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.702655
 - hLp in component INaL (dimensionless): 0.441787
 - a in component Ito (dimensionless): 0.000633
 - iF in component Ito (dimensionless): 0.999864
 - iS in component Ito (dimensionless): 0.616123
 - ap in component Ito (dimensionless): 0.000323
 - iFp in component Ito (dimensionless): 0.999864
 - iSp in component Ito (dimensionless): 0.689715
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934354
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001524
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335255
 - xs1 in component IKs (dimensionless): 0.244725
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997398
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:05:55 (36052): called boinc_finish(0)

</stderr_txt>
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