𝕏

Task 55417625

Name HuVeMOp_20240630101147606520_ORdGradInc_k_25-Pueyo_APDR-conf_341_1
Workunit 26315480
Created 30 Jun 2024, 8:12:52 UTC
Sent 30 Jun 2024, 10:08:52 UTC
Report deadline 3 Jul 2024, 19:44:52 UTC
Received 3 Jul 2024, 15:35:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227058
Run time 2 hours 35 min 46 sec
CPU time 2 hours 34 min 2 sec
Validate state Valid
Credit 61.78
Device peak FLOPS 4.67 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101147606520_ORdGradInc_k_25-Pueyo_APDR-conf_341.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101147606520_ORdGradInc_k_25-Pueyo_APDR-conf_341_1_r275177293_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101147606520_ORdGradInc_k_25-Pueyo_APDR-conf_341_1_r275177293_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.608294
     * GNaL_b in INaL: 0.006090
     * Gto_b in Ito: 0.094630
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030203
     * GKs_b in IKs: 0.001964
     * GK1_b in IK1: 0.162331
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.733432
     * GKb_b in IKb: 0.003844
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026069
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15860954, states[0] = -94.977477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30224301, states[0] = -94.812580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44578781, states[0] = -0.192459, states[40]= 0.004157
Saving checkpoint... 
Iteration: 58474448, states[0] = -94.958440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73632741, states[0] = -44.159146, states[40]= 0.000079
Saving checkpoint... 
Iteration: 88012224, states[0] = 21.644397, states[40]= 0.029680
Saving checkpoint... 
Iteration: 102351984, states[0] = -94.908985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117121406, states[0] = -33.355161, states[40]= 0.000362
Saving checkpoint... 
Iteration: 131894308, states[0] = -94.924514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146850501, states[0] = -94.904998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161330387, states[0] = -94.892873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177896942, states[0] = -94.924041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193278950, states[0] = -94.849280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208396769, states[0] = -94.923682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223446742, states[0] = -94.937144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238273018, states[0] = -94.842450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252942200, states[0] = -94.936064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267802473, states[0] = -94.871439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283017846, states[0] = 21.210365, states[40]= 0.010636
Saving checkpoint... 
Iteration: 298158404, states[0] = -71.311327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 312952290, states[0] = -94.938108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329062081, states[0] = 8.050301, states[40]= 0.004693
Saving checkpoint... 
Iteration: 343163158, states[0] = -78.534392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358025411, states[0] = 19.970550, states[40]= 0.006107
Saving checkpoint... 
Iteration: 373049230, states[0] = 12.821863, states[40]= 0.004721
Saving checkpoint... 
Iteration: 388113237, states[0] = -26.072665, states[40]= 0.000729
Saving checkpoint... 
Iteration: 401906218, states[0] = -94.926404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419811320, states[0] = -94.878447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434760855, states[0] = -94.827417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449311481, states[0] = -94.878547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464387510, states[0] = -94.920000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481023769, states[0] = 20.303192, states[40]= 0.006540
Saving checkpoint... 
Iteration: 495885875, states[0] = -94.919364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510139656, states[0] = -50.298296, states[40]= 0.000030
Saving checkpoint... 
Iteration: 524759486, states[0] = -94.825560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539643316, states[0] = -54.011513, states[40]= 0.000016
Saving checkpoint... 
Iteration: 553635054, states[0] = -45.749327, states[40]= 0.000062
Saving checkpoint... 
Iteration: 568077710, states[0] = 1.043251, states[40]= 0.004286
Saving checkpoint... 
Iteration: 583476968, states[0] = -94.942321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598352751, states[0] = -94.904638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612338247, states[0] = -94.896594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626461422, states[0] = -94.939607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642244407, states[0] = -94.804103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656655959, states[0] = -68.066701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 671988992, states[0] = -94.944065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686437555, states[0] = -94.934603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701651123, states[0] = -62.320010, states[40]= 0.000004
Saving checkpoint... 
Iteration: 716511971, states[0] = 21.708933, states[40]= 0.031534
Saving checkpoint... 
Iteration: 731695216, states[0] = -94.708034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746387085, states[0] = -94.919610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760706690, states[0] = -94.735400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774978848, states[0] = -94.942461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789488602, states[0] = -94.943912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803442250, states[0] = -94.935571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817528103, states[0] = 19.359812, states[40]= 0.005634
Saving checkpoint... 
Iteration: 831428529, states[0] = -94.932302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845338646, states[0] = -94.896638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860285351, states[0] = -94.855091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875252838, states[0] = -94.816250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891679624, states[0] = -94.311803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905686195, states[0] = -94.642898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920443587, states[0] = -94.935769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935082505, states[0] = -1.594754, states[40]= 0.003942
Saving checkpoint... 
Iteration: 950550019, states[0] = 12.544295, states[40]= 0.004719
Saving checkpoint... 
Iteration: 966736695, states[0] = -94.791611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981257098, states[0] = -94.822012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996986222, states[0] = -94.943397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013328456, states[0] = -94.890162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028239805, states[0] = -94.796599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042937057, states[0] = -94.934194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057445012, states[0] = -94.935966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071953074, states[0] = -94.937632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086926904, states[0] = -94.931679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101402233, states[0] = -94.924566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115726151, states[0] = -94.773269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131379641, states[0] = -94.916426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147396039, states[0] = -94.922472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162250500, states[0] = -94.812694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177528975, states[0] = 19.146117, states[40]= 0.005521
Saving checkpoint... 
Iteration: 1191989621, states[0] = -94.943726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206632842, states[0] = -43.619630, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1220739336, states[0] = -94.795690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234444985, states[0] = -94.935815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249090555, states[0] = -6.903311, states[40]= 0.002938
Saving checkpoint... 
Iteration: 1264707239, states[0] = -94.736138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278605221, states[0] = -19.119325, states[40]= 0.001055
Saving checkpoint... 
Iteration: 1293386157, states[0] = -94.918813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308635689, states[0] = -46.367355, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1322692305, states[0] = -94.696878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339167760, states[0] = -86.162112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353395720, states[0] = -94.922193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367687852, states[0] = -94.665488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383255858, states[0] = -94.820002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397758058, states[0] = -94.822950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412392515, states[0] = -94.921029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426736547, states[0] = -94.790986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440559312, states[0] = 9.131196, states[40]= 0.004707
Saving checkpoint... 
Iteration: 1454265883, states[0] = -94.832912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469411001, states[0] = -94.926976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483930390, states[0] = -94.932230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498015445, states[0] = 21.442585, states[40]= 0.015326
Saving checkpoint... 
Iteration: 1512887689, states[0] = -95.169918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527786269, states[0] = -95.037383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542282700, states[0] = -95.192262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556511694, states[0] = -44.127606, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1570313573, states[0] = -46.445695, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1584912432, states[0] = 22.173878, states[40]= 0.029846
Saving checkpoint... 
Iteration: 1599763441, states[0] = -94.987494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615084013, states[0] = -95.060480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630657423, states[0] = -94.878671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644346691, states[0] = 10.113322, states[40]= 0.005533
Saving checkpoint... 
Iteration: 1658359022, states[0] = -95.188593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672792513, states[0] = -95.219110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687574683, states[0] = -7.313595, states[40]= 0.003250
Saving checkpoint... 
Iteration: 1702343760, states[0] = -88.815124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717264501, states[0] = 0.385706, states[40]= 0.004794
Saving checkpoint... 
Iteration: 1733329237, states[0] = -95.150678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749462322, states[0] = -94.981310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763824675, states[0] = -59.758906, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1778745950, states[0] = 10.457628, states[40]= 0.005552
Saving checkpoint... 
Iteration: 1792418719, states[0] = -95.133790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807141645, states[0] = -56.238967, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1821535684, states[0] = 16.827533, states[40]= 0.004952
Saving checkpoint... 
Iteration: 1835581396, states[0] = -1.713287, states[40]= 0.003947
Saving checkpoint... 
Iteration: 1850645338, states[0] = -57.241542, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1865725252, states[0] = -94.781260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880004783, states[0] = 26.759305, states[40]= 0.170422
Saving checkpoint... 
Iteration: 1893907602, states[0] = -94.929896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907915190, states[0] = -94.930643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922776471, states[0] = -94.846658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937468825, states[0] = -94.940977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951424303, states[0] = -94.931011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966361280, states[0] = -94.908169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981834126, states[0] = -94.893214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995925351, states[0] = -94.930666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011500285, states[0] = -59.858687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025597486, states[0] = -12.434483, states[40]= 0.001837
Saving checkpoint... 
Iteration: 2039799406, states[0] = -94.867285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054387414, states[0] = -94.918614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069695834, states[0] = -94.708721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083873870, states[0] = -94.913211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099577614, states[0] = 1.093251, states[40]= 0.004291
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.820186
 - CaMKt in component CaMK (millimolar): 0.007578
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.627490
 - nass in component intracellular_ions (millimolar): 6.627551
 - ki in component intracellular_ions (millimolar): 145.341229
 - kss in component intracellular_ions (millimolar): 145.341210
 - cansr in component intracellular_ions (millimolar): 1.344216
 - cajsr in component intracellular_ions (millimolar): 1.304907
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003648
 - hf in component INa (dimensionless): 0.878577
 - hs in component INa (dimensionless): 0.878571
 - j in component INa (dimensionless): 0.878539
 - hsp in component INa (dimensionless): 0.723149
 - jp in component INa (dimensionless): 0.878517
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.705396
 - hLp in component INaL (dimensionless): 0.442757
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.611715
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.685046
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931712
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999870
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001723
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329508
 - xs1 in component IKs (dimensionless): 0.252215
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997359
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:35:37 (35422): called boinc_finish(0)

</stderr_txt>
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