𝕏

Task 55415875

Name HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_544_0
Workunit 26314608
Created 30 Jun 2024, 8:11:28 UTC
Sent 30 Jun 2024, 9:51:57 UTC
Report deadline 3 Jul 2024, 19:27:57 UTC
Received 1 Jul 2024, 0:28:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230332
Run time 2 hours 16 min 28 sec
CPU time 2 hours 12 min 47 sec
Validate state Valid
Credit 60.03
Device peak FLOPS 3.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 5.83 MB
Peak swap size 1.41 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_544.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_544_0_r1801116883_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_544_0_r1801116883_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.671507
     * GNaL_b in INaL: 0.005353
     * Gto_b in Ito: 0.074467
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030332
     * GKs_b in IKs: 0.001970
     * GK1_b in IK1: 0.181933
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 71.814854
     * GKb_b in IKb: 0.003719
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040786
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17845737, states[0] = -95.126705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35601549, states[0] = -23.352097, states[40]= 0.000784
Saving checkpoint... 
Iteration: 53036334, states[0] = 16.649709, states[40]= 0.005705
Saving checkpoint... 
Iteration: 70622254, states[0] = -41.614077, states[40]= 0.000101
Saving checkpoint... 
Iteration: 87588097, states[0] = -9.037472, states[40]= 0.002559
Saving checkpoint... 
Iteration: 104956006, states[0] = -95.092834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122537307, states[0] = 16.597937, states[40]= 0.005635
Saving checkpoint... 
Iteration: 139924066, states[0] = -95.084330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157338708, states[0] = -95.057102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174752130, states[0] = -94.994397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192218284, states[0] = -94.950550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208323171, states[0] = -95.048714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224831693, states[0] = -95.052943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242134986, states[0] = -54.005227, states[40]= 0.000014
Saving checkpoint... 
Iteration: 259665731, states[0] = -94.222827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276969334, states[0] = -95.090229, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_544.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_544_0_r1801116883_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_544_0_r1801116883_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.671507
     * GNaL_b in INaL: 0.005353
     * Gto_b in Ito: 0.074467
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030332
     * GKs_b in IKs: 0.001970
     * GK1_b in IK1: 0.181933
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 71.814854
     * GKb_b in IKb: 0.003719
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040786
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 276969334
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.090229 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 293934231, states[0] = -95.084649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311285904, states[0] = -95.024632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328645289, states[0] = -66.438398, states[40]= 0.000002
Saving checkpoint... 
Iteration: 346056938, states[0] = 8.923942, states[40]= 0.005001
Saving checkpoint... 
Iteration: 363459355, states[0] = -95.088752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380862931, states[0] = -95.065839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398229071, states[0] = -94.965584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415631165, states[0] = -49.818980, states[40]= 0.000028
Saving checkpoint... 
Iteration: 433040200, states[0] = 15.573060, states[40]= 0.005457
Saving checkpoint... 
Iteration: 450402500, states[0] = -95.077704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467742641, states[0] = -94.982867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485120997, states[0] = -39.343155, states[40]= 0.000142
Saving checkpoint... 
Iteration: 502525660, states[0] = 20.492630, states[40]= 0.007336
Saving checkpoint... 
Iteration: 519862955, states[0] = -95.065767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537183292, states[0] = -94.888250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554582758, states[0] = -4.509557, states[40]= 0.003522
Saving checkpoint... 
Iteration: 571984674, states[0] = -95.091947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589370820, states[0] = -95.068457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606797583, states[0] = -95.032890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624140126, states[0] = -59.890305, states[40]= 0.000005
Saving checkpoint... 
Iteration: 641552002, states[0] = 10.958660, states[40]= 0.005088
Saving checkpoint... 
Iteration: 658948185, states[0] = -95.086852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676335590, states[0] = -95.054411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693647954, states[0] = -70.274845, states[40]= 0.000001
Saving checkpoint... 
Iteration: 711046673, states[0] = 13.082429, states[40]= 0.005207
Saving checkpoint... 
Iteration: 728417307, states[0] = -95.080987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745421586, states[0] = -95.081887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762704122, states[0] = -94.927107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780109508, states[0] = -28.332834, states[40]= 0.000550
Saving checkpoint... 
Iteration: 796756308, states[0] = -94.997881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812826739, states[0] = -95.050006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829657597, states[0] = -87.496728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847016995, states[0] = 22.672651, states[40]= 0.014206
Saving checkpoint... 
Iteration: 864028796, states[0] = 19.546711, states[40]= 0.006617
Saving checkpoint... 
Iteration: 880955606, states[0] = -95.087894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898306149, states[0] = -95.038313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915782362, states[0] = -95.021513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933172921, states[0] = -94.818183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950477350, states[0] = -95.090851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968098498, states[0] = -17.975017, states[40]= 0.001136
Saving checkpoint... 
Iteration: 985366539, states[0] = -95.066770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002782685, states[0] = -95.021719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020095432, states[0] = -15.106985, states[40]= 0.001462
Saving checkpoint... 
Iteration: 1036270370, states[0] = -95.011316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052422633, states[0] = -95.081929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069828024, states[0] = -95.050511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087089939, states[0] = -10.156854, states[40]= 0.002318
Saving checkpoint... 
Iteration: 1104444164, states[0] = -95.085930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121327363, states[0] = -95.050147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138548197, states[0] = 12.481752, states[40]= 0.005168
Saving checkpoint... 
Iteration: 1155891192, states[0] = -95.074336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172971610, states[0] = -95.089991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190163387, states[0] = -93.454501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207365116, states[0] = -95.066145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224616815, states[0] = -35.278058, states[40]= 0.000250
Saving checkpoint... 
Iteration: 1241852952, states[0] = -95.061574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259253698, states[0] = -94.994875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276572117, states[0] = 1.910067, states[40]= 0.004529
Saving checkpoint... 
Iteration: 1293960666, states[0] = -95.088411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311317288, states[0] = -95.044669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328723700, states[0] = -94.957527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346115330, states[0] = -33.855288, states[40]= 0.000301
Saving checkpoint... 
Iteration: 1363505518, states[0] = 28.841957, states[40]= 0.130218
Saving checkpoint... 
Iteration: 1380859404, states[0] = -95.063974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398262566, states[0] = -95.003819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414137180, states[0] = -56.463620, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1430732475, states[0] = -94.969558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448034973, states[0] = 17.479936, states[40]= 0.005822
Saving checkpoint... 
Iteration: 1465437701, states[0] = -95.084597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482736158, states[0] = -94.974300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500084518, states[0] = -9.459764, states[40]= 0.002503
Saving checkpoint... 
Iteration: 1517413637, states[0] = 24.010003, states[40]= 0.026203
Saving checkpoint... 
Iteration: 1534716808, states[0] = -95.243757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552003162, states[0] = -39.909026, states[40]= 0.000133
Saving checkpoint... 
Iteration: 1569316671, states[0] = 22.769114, states[40]= 0.016441
Saving checkpoint... 
Iteration: 1586630797, states[0] = -95.276593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603929325, states[0] = -75.666232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621221942, states[0] = 20.895347, states[40]= 0.010121
Saving checkpoint... 
Iteration: 1638527069, states[0] = -95.275152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655823456, states[0] = -66.074432, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1673027375, states[0] = -95.275952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690305040, states[0] = -42.831986, states[40]= 0.000087
Saving checkpoint... 
Iteration: 1707549785, states[0] = -95.299789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724759043, states[0] = 2.499094, states[40]= 0.005177
Saving checkpoint... 
Iteration: 1742078111, states[0] = -95.322544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759386260, states[0] = -95.213883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776757095, states[0] = -95.146685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793933445, states[0] = -95.283097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811125334, states[0] = -47.134875, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1828431480, states[0] = -95.106345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845673068, states[0] = -94.852755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863025532, states[0] = 20.418411, states[40]= 0.007355
Saving checkpoint... 
Iteration: 1880283160, states[0] = -95.026651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897600886, states[0] = -20.437954, states[40]= 0.000947
Saving checkpoint... 
Iteration: 1914869187, states[0] = -95.068929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932154816, states[0] = -82.584540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949365671, states[0] = -95.066533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966580635, states[0] = -3.080553, states[40]= 0.003800
Saving checkpoint... 
Iteration: 1983861964, states[0] = -95.064767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001081914, states[0] = -3.929002, states[40]= 0.003638
Saving checkpoint... 
Iteration: 2018354876, states[0] = -95.061927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035646396, states[0] = -67.987062, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2052921678, states[0] = -95.081145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070213408, states[0] = -94.941560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087551858, states[0] = 11.016995, states[40]= 0.005091
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.968568
 - CaMKt in component CaMK (millimolar): 0.006792
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.523072
 - nass in component intracellular_ions (millimolar): 6.523130
 - ki in component intracellular_ions (millimolar): 145.457291
 - kss in component intracellular_ions (millimolar): 145.457273
 - cansr in component intracellular_ions (millimolar): 1.302231
 - cajsr in component intracellular_ions (millimolar): 1.264494
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003594
 - hf in component INa (dimensionless): 0.881154
 - hs in component INa (dimensionless): 0.881150
 - j in component INa (dimensionless): 0.881125
 - hsp in component INa (dimensionless): 0.728010
 - jp in component INa (dimensionless): 0.881108
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711969
 - hLp in component INaL (dimensionless): 0.454900
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.621915
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.696838
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934018
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999882
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001575
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334909
 - xs1 in component IKs (dimensionless): 0.242089
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997320
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:28:32 (17244): called boinc_finish(0)

</stderr_txt>
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