𝕏

Task 55415779

Name HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_839_0
Workunit 26314560
Created 30 Jun 2024, 8:11:23 UTC
Sent 30 Jun 2024, 9:51:02 UTC
Report deadline 3 Jul 2024, 19:27:02 UTC
Received 2 Jul 2024, 14:39:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236791
Run time 1 hours 43 min 19 sec
CPU time 1 hours 27 min 19 sec
Validate state Valid
Credit 64.69
Device peak FLOPS 4.25 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 7.33 MB
Peak swap size 1.44 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_839.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_839_0_r51588877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_839_0_r51588877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 108.150836
     * GNaL_b in INaL: 0.004438
     * Gto_b in Ito: 0.069989
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030280
     * GKs_b in IKs: 0.002141
     * GK1_b in IK1: 0.160418
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 72.883045
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026885
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11949591, states[0] = -95.065323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31182610, states[0] = -94.787638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48690245, states[0] = -94.778158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66397247, states[0] = -94.959008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84198092, states[0] = -94.771450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101886153, states[0] = -94.942775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119737414, states[0] = -94.830572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137537173, states[0] = 16.052628, states[40]= 0.005908
Saving checkpoint... 
Iteration: 155511347, states[0] = 24.448174, states[40]= 0.040039
Saving checkpoint... 
Iteration: 173467486, states[0] = -94.955578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191734633, states[0] = -94.822922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209872141, states[0] = -94.931256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227621988, states[0] = -44.800893, states[40]= 0.000058
Saving checkpoint... 
Iteration: 245348063, states[0] = -94.920899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262357978, states[0] = -94.925313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280101141, states[0] = -24.186937, states[40]= 0.000723
Saving checkpoint... 
Iteration: 297738226, states[0] = -94.827514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315438235, states[0] = -94.949473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333191423, states[0] = -94.746002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351120715, states[0] = -43.488598, states[40]= 0.000071
Saving checkpoint... 
Iteration: 368919785, states[0] = -94.945343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384987356, states[0] = -94.957450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401267038, states[0] = -94.862495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416625059, states[0] = -47.961812, states[40]= 0.000035
Saving checkpoint... 
Iteration: 432325983, states[0] = -94.909108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449254555, states[0] = -94.848526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466769112, states[0] = -94.864612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484114975, states[0] = -37.731695, states[40]= 0.000167
Saving checkpoint... 
Iteration: 497896356, states[0] = -94.938964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517031187, states[0] = 18.331868, states[40]= 0.006607
Saving checkpoint... 
Iteration: 535388038, states[0] = -94.936354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553531559, states[0] = 18.197849, states[40]= 0.006550
Saving checkpoint... 
Iteration: 570038886, states[0] = 15.412286, states[40]= 0.005772
Saving checkpoint... 
Iteration: 587670189, states[0] = -94.572334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605492659, states[0] = -94.958004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623428102, states[0] = -94.947145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640978946, states[0] = -94.956195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658435094, states[0] = -94.948641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676389068, states[0] = -94.936616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694341405, states[0] = -94.917331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712037881, states[0] = 15.808598, states[40]= 0.005849
Saving checkpoint... 
Iteration: 729756781, states[0] = -94.851004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747451393, states[0] = -94.951766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765158987, states[0] = -91.264082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782881456, states[0] = -94.934033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800493584, states[0] = -94.958019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817310838, states[0] = -94.899400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832849994, states[0] = -94.921407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849158777, states[0] = -91.077047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862708395, states[0] = -94.778925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877639229, states[0] = -63.321661, states[40]= 0.000003
Saving checkpoint... 
Iteration: 896156232, states[0] = -88.184433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914679137, states[0] = -94.712261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932967267, states[0] = -94.954332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950995812, states[0] = -94.958212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968764612, states[0] = -94.859638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986752896, states[0] = -94.846268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004921223, states[0] = -94.945369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022937033, states[0] = -94.948862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040691741, states[0] = -94.746303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058726236, states[0] = -94.809285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076806387, states[0] = -94.896196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095120314, states[0] = -43.080005, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1113364149, states[0] = -94.927400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131382483, states[0] = -94.934212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149622176, states[0] = -44.981114, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1167472342, states[0] = -94.954985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185545589, states[0] = 12.688892, states[40]= 0.005406
Saving checkpoint... 
Iteration: 1203765481, states[0] = -94.860449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221745331, states[0] = -94.836642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240286585, states[0] = -94.880659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258721788, states[0] = -94.802036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277266716, states[0] = -94.861719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295694164, states[0] = -94.751160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313934599, states[0] = -94.948211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332013106, states[0] = 23.848964, states[40]= 0.028288
Saving checkpoint... 
Iteration: 1350097466, states[0] = -20.594050, states[40]= 0.000927
Saving checkpoint... 
Iteration: 1368040087, states[0] = 14.934015, states[40]= 0.005689
Saving checkpoint... 
Iteration: 1386088060, states[0] = -11.548827, states[40]= 0.002077
Saving checkpoint... 
Iteration: 1404404190, states[0] = -94.940778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422296921, states[0] = -94.889015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440466691, states[0] = -94.953990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458474911, states[0] = -94.955217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472116987, states[0] = -39.730523, states[40]= 0.000125
Saving checkpoint... 
Iteration: 1490325057, states[0] = -94.908038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507447113, states[0] = -95.148220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521400827, states[0] = -39.535452, states[40]= 0.000131
Saving checkpoint... 
Iteration: 1539140736, states[0] = -93.021695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557243852, states[0] = -95.181320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575373254, states[0] = -10.548709, states[40]= 0.002547
Saving checkpoint... 
Iteration: 1593571778, states[0] = -95.216287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611640451, states[0] = 12.152221, states[40]= 0.006391
Saving checkpoint... 
Iteration: 1629799097, states[0] = -95.126643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647929276, states[0] = 17.641767, states[40]= 0.007923
Saving checkpoint... 
Iteration: 1665808720, states[0] = -95.144121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683401541, states[0] = -42.411562, states[40]= 0.000087
Saving checkpoint... 
Iteration: 1701316908, states[0] = 22.764972, states[40]= 0.017000
Saving checkpoint... 
Iteration: 1719314472, states[0] = 23.705345, states[40]= 0.023798
Saving checkpoint... 
Iteration: 1737110692, states[0] = -53.132270, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1755145156, states[0] = -94.656063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773159361, states[0] = -95.035277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791225469, states[0] = -95.169659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1809452311, states[0] = -94.998313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827548342, states[0] = 11.049740, states[40]= 0.005317
Saving checkpoint... 
Iteration: 1845508291, states[0] = 26.059016, states[40]= 0.076526
Saving checkpoint... 
Iteration: 1863496253, states[0] = -94.967977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881462236, states[0] = -94.959034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899150097, states[0] = -78.754998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917060895, states[0] = 5.971945, states[40]= 0.004960
Saving checkpoint... 
Iteration: 1934902773, states[0] = -94.941337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953391364, states[0] = -94.937404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971797868, states[0] = -94.889866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990003202, states[0] = 38.636039, states[40]= 0.116220
Saving checkpoint... 
Iteration: 2008148219, states[0] = -75.314055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025874327, states[0] = -94.930928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043961188, states[0] = -94.952823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062090308, states[0] = -13.652056, states[40]= 0.001701
Saving checkpoint... 
Iteration: 2080080204, states[0] = -4.989146, states[40]= 0.003476
Saving checkpoint... 
Iteration: 2097955659, states[0] = -94.951822, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.833977
 - CaMKt in component CaMK (millimolar): 0.006458
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.483387
 - nass in component intracellular_ions (millimolar): 6.483444
 - ki in component intracellular_ions (millimolar): 145.501256
 - kss in component intracellular_ions (millimolar): 145.501238
 - cansr in component intracellular_ions (millimolar): 1.286041
 - cajsr in component intracellular_ions (millimolar): 1.249146
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003643
 - hf in component INa (dimensionless): 0.878818
 - hs in component INa (dimensionless): 0.878813
 - j in component INa (dimensionless): 0.878785
 - hsp in component INa (dimensionless): 0.723606
 - jp in component INa (dimensionless): 0.878766
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708930
 - hLp in component INaL (dimensionless): 0.452382
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.624849
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.700024
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936977
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999892
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001518
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339442
 - xs1 in component IKs (dimensionless): 0.234259
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997355
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:38:02 (17304): called boinc_finish(0)

</stderr_txt>
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