𝕏

Task 55415616

Name HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_34_0
Workunit 26314479
Created 30 Jun 2024, 8:11:18 UTC
Sent 30 Jun 2024, 9:50:46 UTC
Report deadline 3 Jul 2024, 19:26:46 UTC
Received 30 Jun 2024, 16:25:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232478
Run time 3 hours 1 min 31 sec
CPU time 50 min 40 sec
Validate state Valid
Credit 63.51
Device peak FLOPS 5.61 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.20 MB
Peak swap size 5.32 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_34.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_34_0_r135916301_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_34_0_r135916301_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 97.856508
     * GNaL_b in INaL: 0.006159
     * Gto_b in Ito: 0.080926
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030109
     * GKs_b in IKs: 0.001838
     * GK1_b in IK1: 0.152499
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 66.785293
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022347
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 25102647, states[0] = -19.951435, states[40]= 0.001005
Saving checkpoint... 
Iteration: 43309694, states[0] = -94.825445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70544145, states[0] = 14.735939, states[40]= 0.005079
Saving checkpoint... 
Iteration: 91410609, states[0] = -94.859728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118298058, states[0] = -94.794331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141615112, states[0] = -29.218438, states[40]= 0.000566
Saving checkpoint... 
Iteration: 166000466, states[0] = -33.791975, states[40]= 0.000005
Saving checkpoint... 
Iteration: 198528302, states[0] = 20.055490, states[40]= 0.006158
Saving checkpoint... 
Iteration: 218615830, states[0] = -29.797085, states[40]= 0.000535
Saving checkpoint... 
Iteration: 224813893, states[0] = -94.805154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226643293, states[0] = -56.103167, states[40]= 0.000011
Saving checkpoint... 
Iteration: 241999895, states[0] = -94.872678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245952256, states[0] = -94.864672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251184588, states[0] = -94.532981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253966656, states[0] = -94.867462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258222265, states[0] = -94.687837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264391267, states[0] = -94.847457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272798157, states[0] = -94.791723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291616979, states[0] = -30.816633, states[40]= 0.000482
Saving checkpoint... 
Iteration: 295197281, states[0] = -94.634016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304723299, states[0] = -94.689744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307258211, states[0] = -94.746677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308791720, states[0] = -94.785599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317619565, states[0] = -33.134768, states[40]= 0.000370
Saving checkpoint... 
Iteration: 334008046, states[0] = 24.723112, states[40]= 0.082637
Saving checkpoint... 
Iteration: 348960575, states[0] = -94.866204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364480035, states[0] = -94.869619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368519821, states[0] = 22.066775, states[40]= 0.009391
Saving checkpoint... 
Iteration: 374155592, states[0] = -69.953071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 382723118, states[0] = -94.689331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389219291, states[0] = -94.681921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394571789, states[0] = 3.640109, states[40]= 0.004647
Saving checkpoint... 
Iteration: 410306117, states[0] = -94.798585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415739649, states[0] = -94.718658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425733884, states[0] = -94.708906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443484106, states[0] = -94.870200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458390793, states[0] = -94.847102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484000920, states[0] = 45.831301, states[40]= 0.025942
Saving checkpoint... 
Iteration: 504427971, states[0] = -94.858726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510344572, states[0] = -94.825495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514664523, states[0] = -83.134422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515427467, states[0] = -94.858586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528161220, states[0] = -77.916066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532332681, states[0] = -94.818196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539567874, states[0] = 5.455562, states[40]= 0.004767
Saving checkpoint... 
Iteration: 546038742, states[0] = 16.780791, states[40]= 0.005250
Saving checkpoint... 
Iteration: 550330116, states[0] = -94.816498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552467492, states[0] = -94.867344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564877609, states[0] = -94.841807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579200556, states[0] = -94.642080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582736734, states[0] = -94.713674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590988951, states[0] = -94.870823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604707360, states[0] = -94.657282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612390579, states[0] = -94.846910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628947597, states[0] = -94.863334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644503099, states[0] = 36.402634, states[40]= 0.156378
Saving checkpoint... 
Iteration: 666094660, states[0] = -11.053361, states[40]= 0.002129
Saving checkpoint... 
Iteration: 683806092, states[0] = -94.798364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691517484, states[0] = 22.487711, states[40]= 0.012105
Saving checkpoint... 
Iteration: 722943418, states[0] = -94.862336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756337890, states[0] = -94.821327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789031801, states[0] = 19.037782, states[40]= 0.005721
Saving checkpoint... 
Iteration: 812163217, states[0] = -81.058150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833032743, states[0] = 18.747837, states[40]= 0.005632
Saving checkpoint... 
Iteration: 847271300, states[0] = -94.763068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850552475, states[0] = 11.778612, states[40]= 0.004965
Saving checkpoint... 
Iteration: 883659582, states[0] = -75.443864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917345151, states[0] = -94.825532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936078648, states[0] = 0.115643, states[40]= 0.004285
Saving checkpoint... 
Iteration: 941016595, states[0] = 22.634289, states[40]= 0.013671
Saving checkpoint... 
Iteration: 945248725, states[0] = -94.732565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947617673, states[0] = -31.436208, states[40]= 0.000451
Saving checkpoint... 
Iteration: 951170374, states[0] = -90.766813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977136302, states[0] = -48.963064, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1006367775, states[0] = -94.837146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033901587, states[0] = -94.850497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042350415, states[0] = -94.828390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046483082, states[0] = -94.869603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048750230, states[0] = -94.734739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053216237, states[0] = -94.675366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056125979, states[0] = -38.982018, states[40]= 0.000169
Saving checkpoint... 
Iteration: 1060765926, states[0] = -94.756284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088415527, states[0] = -94.854843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115387371, states[0] = -94.845331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142836389, states[0] = -94.820114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167965851, states[0] = -94.866598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187766344, states[0] = -94.756720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215140978, states[0] = -53.706606, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1227512662, states[0] = 23.254658, states[40]= 0.027898
Saving checkpoint... 
Iteration: 1231369003, states[0] = -94.837547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237290726, states[0] = -94.783937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250854564, states[0] = -94.830459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253676678, states[0] = -93.862635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276409584, states[0] = -94.852906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303620319, states[0] = -33.812727, states[40]= 0.000341
Saving checkpoint... 
Iteration: 1323507921, states[0] = 24.805177, states[40]= 0.085145
Saving checkpoint... 
Iteration: 1351122732, states[0] = -35.998331, states[40]= 0.000256
Saving checkpoint... 
Iteration: 1381603400, states[0] = -18.734612, states[40]= 0.001095
Saving checkpoint... 
Iteration: 1409172520, states[0] = -92.336924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434557262, states[0] = 9.916667, states[40]= 0.004927
Saving checkpoint... 
Iteration: 1461509061, states[0] = 24.190888, states[40]= 0.064620
Saving checkpoint... 
Iteration: 1491127258, states[0] = -40.174686, states[40]= 0.000142
Saving checkpoint... 
Iteration: 1516245822, states[0] = 11.476047, states[40]= 0.005809
Saving checkpoint... 
Iteration: 1543911875, states[0] = -44.809525, states[40]= 0.000073
Saving checkpoint... 
Iteration: 1564227133, states[0] = 19.258605, states[40]= 0.007456
Saving checkpoint... 
Iteration: 1579291179, states[0] = -23.911996, states[40]= 0.000822
Saving checkpoint... 
Iteration: 1585540601, states[0] = 13.409298, states[40]= 0.006056
Saving checkpoint... 
Iteration: 1588405821, states[0] = -95.046476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593427196, states[0] = -63.537255, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1596661502, states[0] = 2.345978, states[40]= 0.005162
Saving checkpoint... 
Iteration: 1599950739, states[0] = 8.370600, states[40]= 0.005661
Saving checkpoint... 
Iteration: 1605260453, states[0] = -95.132055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610815366, states[0] = -49.711446, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1614176135, states[0] = -94.978582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617935147, states[0] = 15.858798, states[40]= 0.006405
Saving checkpoint... 
Iteration: 1627928523, states[0] = -65.420346, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1654413668, states[0] = -95.066150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658721479, states[0] = 21.150566, states[40]= 0.009482
Saving checkpoint... 
Iteration: 1663647292, states[0] = -92.287713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683957715, states[0] = 4.518189, states[40]= 0.005382
Saving checkpoint... 
Iteration: 1707562655, states[0] = -95.137201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727568417, states[0] = -94.954692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747671090, states[0] = -94.965037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771605308, states[0] = -38.815064, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1804301768, states[0] = -94.849566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834023809, states[0] = 20.957775, states[40]= 0.007123
Saving checkpoint... 
Iteration: 1858581428, states[0] = -1.892108, states[40]= 0.004001
Saving checkpoint... 
Iteration: 1884752736, states[0] = -94.744365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891803345, states[0] = -94.800420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899534782, states[0] = 18.052204, states[40]= 0.005470
Saving checkpoint... 
Iteration: 1902590094, states[0] = -7.517372, states[40]= 0.002870
Saving checkpoint... 
Iteration: 1906332529, states[0] = -94.820534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916626553, states[0] = -39.663626, states[40]= 0.000153
Saving checkpoint... 
Iteration: 1919305027, states[0] = -94.798909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921929294, states[0] = -94.860197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926521167, states[0] = 21.781822, states[40]= 0.008415
Saving checkpoint... 
Iteration: 1929617152, states[0] = -31.063654, states[40]= 0.000470
Saving checkpoint... 
Iteration: 1934798655, states[0] = -94.792414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938014088, states[0] = 23.015372, states[40]= 0.020862
Saving checkpoint... 
Iteration: 1941952608, states[0] = -94.864626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946616131, states[0] = -30.114507, states[40]= 0.000519
Saving checkpoint... 
Iteration: 1949643276, states[0] = -56.144561, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1954419143, states[0] = -94.856063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958697472, states[0] = -94.634023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972289939, states[0] = -94.783078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000374791, states[0] = -94.839722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005735897, states[0] = -94.711343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013793364, states[0] = -94.786023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018903564, states[0] = -94.850503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023028128, states[0] = 20.105490, states[40]= 0.006186
Saving checkpoint... 
Iteration: 2026566379, states[0] = 6.118492, states[40]= 0.004801
Saving checkpoint... 
Iteration: 2032559086, states[0] = 9.185412, states[40]= 0.004910
Saving checkpoint... 
Iteration: 2037509679, states[0] = 23.953367, states[40]= 0.055604
Saving checkpoint... 
Iteration: 2042477392, states[0] = -94.867967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046753792, states[0] = -94.739194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051141393, states[0] = -54.135339, states[40]= 0.000016
Saving checkpoint... 
Iteration: 2059570603, states[0] = 4.202164, states[40]= 0.004689
Saving checkpoint... 
Iteration: 2061115676, states[0] = -29.653050, states[40]= 0.000543
Saving checkpoint... 
Iteration: 2064967903, states[0] = -94.866285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2074663136, states[0] = -80.928948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081570121, states[0] = 4.427927, states[40]= 0.004704
Saving checkpoint... 
Iteration: 2085449514, states[0] = -94.862639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089151708, states[0] = -65.222390, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2095237943, states[0] = -94.714543, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.747087
 - CaMKt in component CaMK (millimolar): 0.007394
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.694494
 - nass in component intracellular_ions (millimolar): 6.694554
 - ki in component intracellular_ions (millimolar): 145.276956
 - kss in component intracellular_ions (millimolar): 145.276938
 - cansr in component intracellular_ions (millimolar): 1.336586
 - cajsr in component intracellular_ions (millimolar): 1.297776
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003675
 - hf in component INa (dimensionless): 0.877289
 - hs in component INa (dimensionless): 0.877284
 - j in component INa (dimensionless): 0.877250
 - hsp in component INa (dimensionless): 0.720737
 - jp in component INa (dimensionless): 0.877227
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.703824
 - hLp in component INaL (dimensionless): 0.441605
 - a in component Ito (dimensionless): 0.000630
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.613055
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.686037
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930559
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999868
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001697
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.342056
 - xs1 in component IKs (dimensionless): 0.250761
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997378
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:45:22 (15428): called boinc_finish(0)

</stderr_txt>
]]>


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