𝕏

Task 55415570

Name HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_933_0
Workunit 26314456
Created 30 Jun 2024, 8:11:18 UTC
Sent 30 Jun 2024, 9:46:57 UTC
Report deadline 3 Jul 2024, 19:22:57 UTC
Received 30 Jun 2024, 15:18:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214880
Run time 1 hours 32 min 50 sec
CPU time 1 hours 27 min 17 sec
Validate state Valid
Credit 60.34
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.22 MB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.16.20</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_933.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_933_0_r203937712_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_933_0_r203937712_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.907004
     * GNaL_b in INaL: 0.004949
     * Gto_b in Ito: 0.070760
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031359
     * GKs_b in IKs: 0.002003
     * GK1_b in IK1: 0.161273
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 73.781925
     * GKb_b in IKb: 0.003680
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035659
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14039527, states[0] = 13.977786, states[40]= 0.005676
Saving checkpoint... 
Iteration: 27957746, states[0] = -95.038243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41739102, states[0] = -94.894178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55607405, states[0] = -31.818399, states[40]= 0.000363
Saving checkpoint... 
Iteration: 69736846, states[0] = -94.866098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83516721, states[0] = 22.851574, states[40]= 0.015437
Saving checkpoint... 
Iteration: 97524129, states[0] = 20.821160, states[40]= 0.008245
Saving checkpoint... 
Iteration: 110993911, states[0] = -94.982854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124937091, states[0] = -94.972345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138823426, states[0] = -94.930750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152940693, states[0] = -94.971117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167060741, states[0] = 6.374733, states[40]= 0.004965
Saving checkpoint... 
Iteration: 178501918, states[0] = 46.961541, states[40]= 0.073422
Saving checkpoint... 
Iteration: 192745797, states[0] = -94.860352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207045942, states[0] = 12.826932, states[40]= 0.005358
Saving checkpoint... 
Iteration: 221039018, states[0] = 15.629100, states[40]= 0.005706
Saving checkpoint... 
Iteration: 235433387, states[0] = -94.968263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249883690, states[0] = -94.955186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263575837, states[0] = -1.657224, states[40]= 0.004104
Saving checkpoint... 
Iteration: 277744520, states[0] = -94.858236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291307428, states[0] = -94.918309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305210367, states[0] = -94.805788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319111402, states[0] = -34.127113, states[40]= 0.000275
Saving checkpoint... 
Iteration: 333255132, states[0] = -94.871189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346871682, states[0] = -94.950888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361157325, states[0] = -90.622810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374756557, states[0] = -94.872805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388322300, states[0] = -94.927690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401940023, states[0] = -94.969373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415949876, states[0] = -94.971187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429765622, states[0] = -94.882682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443790836, states[0] = -94.905867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457418202, states[0] = -94.964658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471487163, states[0] = -94.976708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484914090, states[0] = -94.963649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499143452, states[0] = -69.508804, states[40]= 0.000001
Saving checkpoint... 
Iteration: 512769720, states[0] = -94.886825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526865624, states[0] = -94.948501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541135773, states[0] = -59.995975, states[40]= 0.000005
Saving checkpoint... 
Iteration: 555414735, states[0] = -94.963771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569317129, states[0] = -94.924464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583670448, states[0] = -94.640457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596790028, states[0] = -94.905133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611131918, states[0] = -55.654284, states[40]= 0.000010
Saving checkpoint... 
Iteration: 625016189, states[0] = 23.086456, states[40]= 0.016675
Saving checkpoint... 
Iteration: 638810419, states[0] = -94.920119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652766997, states[0] = -94.883990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666514366, states[0] = 23.563621, states[40]= 0.022201
Saving checkpoint... 
Iteration: 680499079, states[0] = -94.977996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694518375, states[0] = 22.520019, states[40]= 0.012688
Saving checkpoint... 
Iteration: 708671395, states[0] = -94.664234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722335707, states[0] = -94.934934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736657755, states[0] = -91.038846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750553502, states[0] = 9.635554, states[40]= 0.005144
Saving checkpoint... 
Iteration: 764420523, states[0] = -94.965044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778510471, states[0] = 24.835427, states[40]= 0.047712
Saving checkpoint... 
Iteration: 791832961, states[0] = -94.933457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805726651, states[0] = -94.832618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819588930, states[0] = -12.011300, states[40]= 0.001988
Saving checkpoint... 
Iteration: 833395691, states[0] = -94.958518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847896968, states[0] = -94.958883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861749248, states[0] = -94.863866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875709665, states[0] = -94.804217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884459851, states[0] = -94.972625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898734787, states[0] = -94.844647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912831431, states[0] = -94.932574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926837631, states[0] = -94.935816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940911005, states[0] = -94.962641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954925658, states[0] = -94.966110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968884132, states[0] = -94.954873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982904970, states[0] = -94.961044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996163904, states[0] = -94.071377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006666179, states[0] = -94.396336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020772679, states[0] = -94.889477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034795668, states[0] = -94.909367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048841402, states[0] = -94.937635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062507228, states[0] = 27.108348, states[40]= 0.094647
Saving checkpoint... 
Iteration: 1076456266, states[0] = -94.971940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090805411, states[0] = -94.916476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104434032, states[0] = -94.967816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118888084, states[0] = -94.956062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133174468, states[0] = -94.709794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141108926, states[0] = -31.664608, states[40]= 0.000371
Saving checkpoint... 
Iteration: 1152099182, states[0] = -22.024525, states[40]= 0.000837
Saving checkpoint... 
Iteration: 1166369422, states[0] = -94.949620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180490457, states[0] = -94.976743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191985382, states[0] = -94.976112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206501463, states[0] = 49.561509, states[40]= 0.050493
Saving checkpoint... 
Iteration: 1220485139, states[0] = -94.976067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234478940, states[0] = -94.975252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248653083, states[0] = -84.821595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262709031, states[0] = -94.802874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276812021, states[0] = -94.920843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291115999, states[0] = -38.739211, states[40]= 0.000146
Saving checkpoint... 
Iteration: 1305340851, states[0] = -94.937232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319298305, states[0] = -94.911221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333761963, states[0] = -94.878324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347705619, states[0] = -94.796590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361707151, states[0] = -94.799405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375736205, states[0] = -94.846407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389613650, states[0] = -36.372109, states[40]= 0.000204
Saving checkpoint... 
Iteration: 1403235771, states[0] = -94.845781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417061779, states[0] = 5.910279, states[40]= 0.004934
Saving checkpoint... 
Iteration: 1431056844, states[0] = 8.167691, states[40]= 0.005066
Saving checkpoint... 
Iteration: 1445233847, states[0] = -94.843016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459579638, states[0] = -4.233375, states[40]= 0.003628
Saving checkpoint... 
Iteration: 1473759770, states[0] = -94.875849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487911002, states[0] = -94.962358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501840231, states[0] = 13.357994, states[40]= 0.006315
Saving checkpoint... 
Iteration: 1515720107, states[0] = -62.352577, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1530001029, states[0] = 49.117368, states[40]= 0.019075
Saving checkpoint... 
Iteration: 1544175186, states[0] = -11.844106, states[40]= 0.002261
Saving checkpoint... 
Iteration: 1557903595, states[0] = 37.413139, states[40]= 0.102204
Saving checkpoint... 
Iteration: 1571797260, states[0] = -37.193595, states[40]= 0.000186
Saving checkpoint... 
Iteration: 1585862577, states[0] = -0.853645, states[40]= 0.004731
Saving checkpoint... 
Iteration: 1600135885, states[0] = -95.201510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613530546, states[0] = -82.452317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627934103, states[0] = -88.508575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641806231, states[0] = -95.161245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655998151, states[0] = -95.258525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670051318, states[0] = -95.221158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683997882, states[0] = -38.297254, states[40]= 0.000159
Saving checkpoint... 
Iteration: 1698178347, states[0] = -95.107601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712173843, states[0] = -11.197089, states[40]= 0.002409
Saving checkpoint... 
Iteration: 1726513158, states[0] = 24.263928, states[40]= 0.029102
Saving checkpoint... 
Iteration: 1740501562, states[0] = -95.153873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1754626456, states[0] = -95.192238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768454333, states[0] = -95.224395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1782714111, states[0] = -57.763730, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1796671611, states[0] = -95.239933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810567751, states[0] = 1.659910, states[40]= 0.004657
Saving checkpoint... 
Iteration: 1823863616, states[0] = -94.979860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837732690, states[0] = -94.863494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851669905, states[0] = -94.667008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865692386, states[0] = -94.780384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879703207, states[0] = -94.798249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893709409, states[0] = -94.807471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907539793, states[0] = 15.286563, states[40]= 0.005656
Saving checkpoint... 
Iteration: 1921322640, states[0] = -94.928908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935408483, states[0] = -94.962655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949545811, states[0] = 12.873452, states[40]= 0.005363
Saving checkpoint... 
Iteration: 1963665212, states[0] = -94.289107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973861078, states[0] = -94.946297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979345020, states[0] = -94.939190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990875913, states[0] = -94.951751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998588130, states[0] = -11.276140, states[40]= 0.002129
Saving checkpoint... 
Iteration: 2004882788, states[0] = -94.954011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017088296, states[0] = -11.425604, states[40]= 0.002099
Saving checkpoint... 
Iteration: 2028803551, states[0] = -94.914718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035436427, states[0] = -94.967842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048818544, states[0] = -94.924572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059490312, states[0] = -94.976262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073918945, states[0] = -94.963977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087845864, states[0] = -94.939211, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.853208
 - CaMKt in component CaMK (millimolar): 0.006540
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.471514
 - nass in component intracellular_ions (millimolar): 6.471572
 - ki in component intracellular_ions (millimolar): 145.512159
 - kss in component intracellular_ions (millimolar): 145.512140
 - cansr in component intracellular_ions (millimolar): 1.289525
 - cajsr in component intracellular_ions (millimolar): 1.252465
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003636
 - hf in component INa (dimensionless): 0.879154
 - hs in component INa (dimensionless): 0.879150
 - j in component INa (dimensionless): 0.879122
 - hsp in component INa (dimensionless): 0.724238
 - jp in component INa (dimensionless): 0.879104
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709641
 - hLp in component INaL (dimensionless): 0.453573
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.625357
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.700559
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936334
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001528
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337945
 - xs1 in component IKs (dimensionless): 0.235409
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997350
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:18:04 (8696): called boinc_finish(0)

</stderr_txt>
]]>


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