𝕏

Task 55415194

Name HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_622_0
Workunit 26314268
Created 30 Jun 2024, 8:11:03 UTC
Sent 30 Jun 2024, 9:51:29 UTC
Report deadline 3 Jul 2024, 19:27:29 UTC
Received 3 Jul 2024, 0:40:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240970
Run time 3 hours 4 min 25 sec
CPU time 2 hours 20 min 54 sec
Validate state Valid
Credit 62.88
Device peak FLOPS 3.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.75 MB
Peak swap size 5.34 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_622.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_622_0_r486110526_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_622_0_r486110526_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 94.479481
     * GNaL_b in INaL: 0.005338
     * Gto_b in Ito: 0.089434
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032720
     * GKs_b in IKs: 0.001981
     * GK1_b in IK1: 0.165841
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.163553
     * GKb_b in IKb: 0.003768
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029970
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14896332, states[0] = -95.002530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27420323, states[0] = -94.978060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39969292, states[0] = -94.969834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52593560, states[0] = -15.489132, states[40]= 0.001401
Saving checkpoint... 
Iteration: 65200649, states[0] = -94.750492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77662988, states[0] = -92.989492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90246710, states[0] = -94.821123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102674714, states[0] = -94.633817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114946269, states[0] = -94.935063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127222126, states[0] = -94.778139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140154014, states[0] = -81.016529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152816938, states[0] = -94.883359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165383724, states[0] = -94.915833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177891134, states[0] = -94.918105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190365732, states[0] = -94.908550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203030862, states[0] = 18.083362, states[40]= 0.005614
Saving checkpoint... 
Iteration: 215482085, states[0] = -94.937727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227972108, states[0] = -94.936216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240264432, states[0] = -94.836007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252703457, states[0] = -94.740487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265243100, states[0] = -94.808775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277825272, states[0] = -94.887576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290387182, states[0] = -94.916226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302769080, states[0] = -94.841067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315219907, states[0] = -94.771748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327741412, states[0] = -94.806284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340144675, states[0] = -66.685726, states[40]= 0.000002
Saving checkpoint... 
Iteration: 352579697, states[0] = -2.971760, states[40]= 0.003760
Saving checkpoint... 
Iteration: 365151038, states[0] = -75.811652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377663780, states[0] = -93.006968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390061040, states[0] = 6.819286, states[40]= 0.004730
Saving checkpoint... 
Iteration: 402692938, states[0] = -94.718149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415234592, states[0] = -94.796034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427563018, states[0] = 5.946693, states[40]= 0.004696
Saving checkpoint... 
Iteration: 440154425, states[0] = -81.540847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452437835, states[0] = -94.929766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464841919, states[0] = -94.896875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477505315, states[0] = 26.231243, states[40]= 0.149009
Saving checkpoint... 
Iteration: 489971735, states[0] = -94.935858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502361741, states[0] = -94.906288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514708962, states[0] = -94.751196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527019340, states[0] = 20.876394, states[40]= 0.009521
Saving checkpoint... 
Iteration: 539774525, states[0] = -94.846631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552410308, states[0] = -94.923069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565030046, states[0] = 18.328418, states[40]= 0.005705
Saving checkpoint... 
Iteration: 577422608, states[0] = -94.926222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589804092, states[0] = -94.872806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602481475, states[0] = -94.937199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614826232, states[0] = -94.887893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627377161, states[0] = -94.912394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639670493, states[0] = -94.458585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652085959, states[0] = -7.590981, states[40]= 0.002831
Saving checkpoint... 
Iteration: 664656389, states[0] = -84.909561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677296748, states[0] = -94.866945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689838543, states[0] = -94.894913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702327027, states[0] = -94.888311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714895323, states[0] = -94.918557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727485122, states[0] = -94.937607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740126557, states[0] = -46.386636, states[40]= 0.000049
Saving checkpoint... 
Iteration: 752456047, states[0] = -94.933075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764955702, states[0] = -94.933004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777428447, states[0] = -94.927458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789963829, states[0] = -94.934380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802203422, states[0] = -94.739956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814704539, states[0] = -94.742206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827149652, states[0] = -73.633703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 839876656, states[0] = -94.912049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852571759, states[0] = 1.715602, states[40]= 0.004406
Saving checkpoint... 
Iteration: 864940796, states[0] = -94.930079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877309622, states[0] = -94.876684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889720602, states[0] = -94.772546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902066664, states[0] = 4.266189, states[40]= 0.004609
Saving checkpoint... 
Iteration: 914421545, states[0] = -94.925715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926819698, states[0] = -94.883545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939543289, states[0] = 13.868070, states[40]= 0.004936
Saving checkpoint... 
Iteration: 952176021, states[0] = -94.644274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964657519, states[0] = -86.726639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977088185, states[0] = -9.456597, states[40]= 0.002437
Saving checkpoint... 
Iteration: 989483787, states[0] = -94.937234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001981604, states[0] = -94.936924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014563541, states[0] = 5.711857, states[40]= 0.004686
Saving checkpoint... 
Iteration: 1026957689, states[0] = -94.933163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039083804, states[0] = -5.894342, states[40]= 0.003191
Saving checkpoint... 
Iteration: 1051542692, states[0] = 14.087429, states[40]= 0.004950
Saving checkpoint... 
Iteration: 1063943562, states[0] = -94.930493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076503774, states[0] = 31.138743, states[40]= 0.168486
Saving checkpoint... 
Iteration: 1088993114, states[0] = -94.938378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101535459, states[0] = 16.627421, states[40]= 0.005243
Saving checkpoint... 
Iteration: 1113891377, states[0] = -94.917001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126446874, states[0] = -94.931098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139055726, states[0] = 9.056395, states[40]= 0.004790
Saving checkpoint... 
Iteration: 1151363145, states[0] = -94.906414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163785450, states[0] = -94.856786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176077573, states[0] = -1.607610, states[40]= 0.003986
Saving checkpoint... 
Iteration: 1188457265, states[0] = -94.932970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201061288, states[0] = 6.711453, states[40]= 0.004726
Saving checkpoint... 
Iteration: 1213694262, states[0] = -94.720441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226255372, states[0] = -94.824384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238768842, states[0] = -94.840106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251345902, states[0] = -94.898341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263819060, states[0] = -94.882880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276137710, states[0] = -58.415349, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1288699436, states[0] = -94.731388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301135686, states[0] = -56.168093, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1313480444, states[0] = -94.936533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324957035, states[0] = -94.932829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336832855, states[0] = -94.891274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349438957, states[0] = -94.929343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362193030, states[0] = -94.717640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374474545, states[0] = -94.935633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387021332, states[0] = 20.504106, states[40]= 0.008042
Saving checkpoint... 
Iteration: 1399407815, states[0] = -94.921759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411783853, states[0] = -94.855124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424235518, states[0] = -94.796711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436690616, states[0] = -94.712189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449104218, states[0] = -24.483927, states[40]= 0.000722
Saving checkpoint... 
Iteration: 1461955460, states[0] = -94.932450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474723712, states[0] = -94.777525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487374522, states[0] = -94.910765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499831449, states[0] = -94.890344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512298975, states[0] = -95.169551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1524831631, states[0] = -95.118512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537325047, states[0] = -68.843410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1550115446, states[0] = 21.696620, states[40]= 0.017681
Saving checkpoint... 
Iteration: 1562346006, states[0] = -95.159110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574596758, states[0] = -95.086451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586930344, states[0] = -95.144708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599356386, states[0] = 3.558809, states[40]= 0.005175
Saving checkpoint... 
Iteration: 1611785722, states[0] = -95.067648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624313729, states[0] = -55.384722, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1636647363, states[0] = -94.784951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649287971, states[0] = -95.073940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661598968, states[0] = -95.096867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674208642, states[0] = -95.114875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686588257, states[0] = -95.207509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699078444, states[0] = -95.052399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711117588, states[0] = -95.129930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723391427, states[0] = -95.081796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1736015126, states[0] = -95.125983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748706549, states[0] = 25.397773, states[40]= 0.109897
Saving checkpoint... 
Iteration: 1761161630, states[0] = -95.007076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773644926, states[0] = 9.863229, states[40]= 0.005651
Saving checkpoint... 
Iteration: 1786127815, states[0] = -95.145249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798489426, states[0] = -95.208395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811095405, states[0] = -18.834323, states[40]= 0.001068
Saving checkpoint... 
Iteration: 1823596959, states[0] = -19.420120, states[40]= 0.001009
Saving checkpoint... 
Iteration: 1835666927, states[0] = -94.303734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848060037, states[0] = 6.934076, states[40]= 0.004742
Saving checkpoint... 
Iteration: 1860554413, states[0] = 9.393496, states[40]= 0.004801
Saving checkpoint... 
Iteration: 1873157875, states[0] = -88.043696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885509130, states[0] = 22.523468, states[40]= 0.063551
Saving checkpoint... 
Iteration: 1897862959, states[0] = -94.909295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910416870, states[0] = -94.926181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922843819, states[0] = -94.898398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935182207, states[0] = -94.689864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947125147, states[0] = -44.973319, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1957828636, states[0] = -94.888869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968940391, states[0] = -94.929532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981335183, states[0] = -94.892334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993891800, states[0] = -94.916620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006163312, states[0] = -92.769622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018801392, states[0] = -94.869697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031317247, states[0] = -94.881114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043822953, states[0] = -94.884784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056175664, states[0] = -94.638235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068794862, states[0] = -94.864315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081122731, states[0] = -42.449594, states[40]= 0.000090
Saving checkpoint... 
Iteration: 2093364140, states[0] = -94.906087, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.814283
 - CaMKt in component CaMK (millimolar): 0.007159
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.563531
 - nass in component intracellular_ions (millimolar): 6.563591
 - ki in component intracellular_ions (millimolar): 145.410715
 - kss in component intracellular_ions (millimolar): 145.410696
 - cansr in component intracellular_ions (millimolar): 1.322664
 - cajsr in component intracellular_ions (millimolar): 1.284517
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003651
 - hf in component INa (dimensionless): 0.878473
 - hs in component INa (dimensionless): 0.878468
 - j in component INa (dimensionless): 0.878439
 - hsp in component INa (dimensionless): 0.722957
 - jp in component INa (dimensionless): 0.878419
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707855
 - hLp in component INaL (dimensionless): 0.450164
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.621866
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.696991
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936985
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999892
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001637
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.320616
 - xs1 in component IKs (dimensionless): 0.238980
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997360
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:40:00 (15076): called boinc_finish(0)

</stderr_txt>
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