𝕏

Task 55414757

Name HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_303_1
Workunit 26314049
Created 30 Jun 2024, 8:10:52 UTC
Sent 30 Jun 2024, 9:40:21 UTC
Report deadline 3 Jul 2024, 19:16:21 UTC
Received 2 Jul 2024, 14:43:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234921
Run time 2 hours 5 min 47 sec
CPU time 2 hours 5 min 42 sec
Validate state Valid
Credit 59.71
Device peak FLOPS 5.54 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.47 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_303.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_303_1_r1213086952_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630101044700191_ORdGradInc_k_25-Pueyo_APDR-conf_303_1_r1213086952_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 96.619494
     * GNaL_b in INaL: 0.006069
     * Gto_b in Ito: 0.098004
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034146
     * GKs_b in IKs: 0.002061
     * GK1_b in IK1: 0.178709
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 73.382617
     * GKb_b in IKb: 0.003790
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038001
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16884769, states[0] = -95.266004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33724850, states[0] = -95.112253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50552472, states[0] = 10.081161, states[40]= 0.004704
Saving checkpoint... 
Iteration: 67392353, states[0] = -95.206656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84216076, states[0] = -95.063908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100888068, states[0] = -95.196313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117589097, states[0] = -9.722112, states[40]= 0.002354
Saving checkpoint... 
Iteration: 134338200, states[0] = -95.173781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151151719, states[0] = -81.126128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167845723, states[0] = -95.176096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184483802, states[0] = -95.210757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201115814, states[0] = -35.185913, states[40]= 0.000249
Saving checkpoint... 
Iteration: 217798143, states[0] = -95.148159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234639377, states[0] = -61.491271, states[40]= 0.000004
Saving checkpoint... 
Iteration: 251458032, states[0] = -95.206722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268295595, states[0] = -95.146139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285102029, states[0] = -21.723798, states[40]= 0.000842
Saving checkpoint... 
Iteration: 301915488, states[0] = -95.198393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318721592, states[0] = -95.064013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335442780, states[0] = -95.204017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352117365, states[0] = -36.722651, states[40]= 0.000203
Saving checkpoint... 
Iteration: 369028070, states[0] = 18.653758, states[40]= 0.005780
Saving checkpoint... 
Iteration: 386526852, states[0] = 18.951538, states[40]= 0.005986
Saving checkpoint... 
Iteration: 403964637, states[0] = -95.207569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421373113, states[0] = -95.186114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438738989, states[0] = -95.089157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456137786, states[0] = -59.482923, states[40]= 0.000006
Saving checkpoint... 
Iteration: 473600761, states[0] = -20.497550, states[40]= 0.000913
Saving checkpoint... 
Iteration: 491058293, states[0] = 8.261626, states[40]= 0.004670
Saving checkpoint... 
Iteration: 508538986, states[0] = 15.410195, states[40]= 0.004911
Saving checkpoint... 
Iteration: 525999269, states[0] = -95.211883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543453993, states[0] = -95.205800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560874490, states[0] = -95.186487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578265216, states[0] = -95.119510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595628889, states[0] = -49.009062, states[40]= 0.000033
Saving checkpoint... 
Iteration: 612967283, states[0] = -95.207803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630155229, states[0] = -87.510241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647424919, states[0] = -95.200243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664860094, states[0] = -95.181110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682314957, states[0] = -95.158828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699731673, states[0] = -95.078887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717015856, states[0] = 20.791469, states[40]= 0.014814
Saving checkpoint... 
Iteration: 734282383, states[0] = -95.135292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751603081, states[0] = -22.738421, states[40]= 0.000790
Saving checkpoint... 
Iteration: 768393522, states[0] = -95.192323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785197201, states[0] = -95.020412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801991807, states[0] = -95.210848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818607904, states[0] = -27.405780, states[40]= 0.000575
Saving checkpoint... 
Iteration: 835217497, states[0] = -95.057017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852040885, states[0] = 14.767549, states[40]= 0.004850
Saving checkpoint... 
Iteration: 868761959, states[0] = -95.115947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885508947, states[0] = 21.648206, states[40]= 0.067525
Saving checkpoint... 
Iteration: 902286154, states[0] = -95.138300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919039030, states[0] = 15.395596, states[40]= 0.004910
Saving checkpoint... 
Iteration: 935897878, states[0] = -95.193427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953261342, states[0] = -95.115237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970622878, states[0] = -42.414393, states[40]= 0.000090
Saving checkpoint... 
Iteration: 987820475, states[0] = -95.161879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005092908, states[0] = -12.989209, states[40]= 0.001744
Saving checkpoint... 
Iteration: 1022474881, states[0] = -95.208566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039907266, states[0] = -95.195832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057305122, states[0] = -95.152248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074575379, states[0] = 0.181624, states[40]= 0.004172
Saving checkpoint... 
Iteration: 1092019654, states[0] = 20.343328, states[40]= 0.009026
Saving checkpoint... 
Iteration: 1109491083, states[0] = -95.210537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126964618, states[0] = -95.207032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144438017, states[0] = -95.202527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161913982, states[0] = -95.197390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179364727, states[0] = -95.182515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196567207, states[0] = 4.376334, states[40]= 0.004536
Saving checkpoint... 
Iteration: 1213750421, states[0] = -95.102880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231124120, states[0] = -43.742287, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1248522403, states[0] = 19.892247, states[40]= 0.007284
Saving checkpoint... 
Iteration: 1265982428, states[0] = -95.209373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283373830, states[0] = -95.185725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300682531, states[0] = -94.989070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318006559, states[0] = 23.150620, states[40]= 0.119656
Saving checkpoint... 
Iteration: 1335440913, states[0] = -95.202931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352928768, states[0] = -95.200535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370338409, states[0] = -95.171098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387685709, states[0] = -94.996289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405157162, states[0] = -90.343345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422635269, states[0] = -56.420285, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1440127519, states[0] = -47.469742, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1457635795, states[0] = -57.051709, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1475017099, states[0] = 20.666406, states[40]= 0.012229
Saving checkpoint... 
Iteration: 1492425683, states[0] = -95.199783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509866457, states[0] = -95.396231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527184550, states[0] = -95.302980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1544452652, states[0] = 5.994938, states[40]= 0.005272
Saving checkpoint... 
Iteration: 1561935024, states[0] = -91.527169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579367647, states[0] = -95.288218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596665267, states[0] = -2.515812, states[40]= 0.004281
Saving checkpoint... 
Iteration: 1613923485, states[0] = -95.395158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630844499, states[0] = 9.972023, states[40]= 0.005541
Saving checkpoint... 
Iteration: 1647935525, states[0] = 14.208543, states[40]= 0.005986
Saving checkpoint... 
Iteration: 1665039294, states[0] = 12.485198, states[40]= 0.005760
Saving checkpoint... 
Iteration: 1682333621, states[0] = -95.409301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699457575, states[0] = -95.434249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716578322, states[0] = -95.451115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733881451, states[0] = -95.325126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751363900, states[0] = -95.439818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768805796, states[0] = 25.404874, states[40]= 0.128508
Saving checkpoint... 
Iteration: 1786103211, states[0] = -95.366348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803388846, states[0] = -95.243449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820228504, states[0] = -95.108025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836953968, states[0] = -95.226252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1854120318, states[0] = -40.665148, states[40]= 0.000116
Saving checkpoint... 
Iteration: 1870728725, states[0] = -95.081577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887146869, states[0] = -72.771193, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1903561030, states[0] = 7.056376, states[40]= 0.004645
Saving checkpoint... 
Iteration: 1919966901, states[0] = -95.208463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936428364, states[0] = -95.201018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953036224, states[0] = 16.301237, states[40]= 0.005033
Saving checkpoint... 
Iteration: 1969700886, states[0] = -95.026993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986429873, states[0] = -95.200463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003353305, states[0] = -95.177432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020724693, states[0] = -95.067585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038045937, states[0] = 12.985925, states[40]= 0.004750
Saving checkpoint... 
Iteration: 2055487457, states[0] = -95.209369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072804796, states[0] = -95.151223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090086320, states[0] = -7.226627, states[40]= 0.002872
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.086613
 - CaMKt in component CaMK (millimolar): 0.007167
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.487326
 - nass in component intracellular_ions (millimolar): 6.487388
 - ki in component intracellular_ions (millimolar): 145.487172
 - kss in component intracellular_ions (millimolar): 145.487151
 - cansr in component intracellular_ions (millimolar): 1.320629
 - cajsr in component intracellular_ions (millimolar): 1.282367
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003552
 - hf in component INa (dimensionless): 0.883170
 - hs in component INa (dimensionless): 0.883166
 - j in component INa (dimensionless): 0.883140
 - hsp in component INa (dimensionless): 0.731832
 - jp in component INa (dimensionless): 0.883122
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.715471
 - hLp in component INaL (dimensionless): 0.459703
 - a in component Ito (dimensionless): 0.000616
 - iF in component Ito (dimensionless): 0.999874
 - iS in component Ito (dimensionless): 0.624422
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999874
 - iSp in component Ito (dimensionless): 0.700466
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937244
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999893
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001625
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.312441
 - xs1 in component IKs (dimensionless): 0.240296
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997288
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:43:25 (747885): called boinc_finish(0)

</stderr_txt>
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