𝕏

Task 55414134

Name HuVeMOp_20240630093703370580_ORdGradInc_k_25-Pueyo_APDR-conf_764_1
Workunit 26313759
Created 30 Jun 2024, 7:38:02 UTC
Sent 30 Jun 2024, 9:39:11 UTC
Report deadline 3 Jul 2024, 19:15:11 UTC
Received 30 Jun 2024, 13:26:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240368
Run time 2 hours 51 min 27 sec
CPU time 2 hours 46 min 28 sec
Validate state Valid
Credit 61.94
Device peak FLOPS 4.18 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.11 MB
Peak swap size 6.23 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093703370580_ORdGradInc_k_25-Pueyo_APDR-conf_764.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093703370580_ORdGradInc_k_25-Pueyo_APDR-conf_764_1_r39829185_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093703370580_ORdGradInc_k_25-Pueyo_APDR-conf_764_1_r39829185_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.815260
     * GNaL_b in INaL: 0.005621
     * Gto_b in Ito: 0.090911
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032022
     * GKs_b in IKs: 0.001898
     * GK1_b in IK1: 0.181843
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 72.140997
     * GKb_b in IKb: 0.003712
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030939
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13673127, states[0] = -95.057277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27685865, states[0] = -95.047233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41313305, states[0] = -95.186923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55000824, states[0] = 46.290310, states[40]= 0.015293
Saving checkpoint... 
Iteration: 68731746, states[0] = -95.091064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82542040, states[0] = 14.494883, states[40]= 0.005055
Saving checkpoint... 
Iteration: 96274209, states[0] = -95.132456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109932922, states[0] = -95.204421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123668085, states[0] = -94.793652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137255742, states[0] = -95.109697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150836817, states[0] = -95.170539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164496096, states[0] = -95.211021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178369464, states[0] = -95.183741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192116253, states[0] = -34.804741, states[40]= 0.000269
Saving checkpoint... 
Iteration: 205619057, states[0] = -37.572418, states[40]= 0.000186
Saving checkpoint... 
Iteration: 219416257, states[0] = -95.197099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233184040, states[0] = -94.992381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246818614, states[0] = -95.159581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260552980, states[0] = 10.579287, states[40]= 0.004863
Saving checkpoint... 
Iteration: 274476277, states[0] = -95.207776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288188030, states[0] = -95.001011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301874433, states[0] = -95.184928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315513429, states[0] = 21.848749, states[40]= 0.024724
Saving checkpoint... 
Iteration: 329370337, states[0] = -95.183459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343044279, states[0] = 13.847647, states[40]= 0.004992
Saving checkpoint... 
Iteration: 356881072, states[0] = -95.187105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370624234, states[0] = -42.844357, states[40]= 0.000087
Saving checkpoint... 
Iteration: 384370422, states[0] = -95.183447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398227378, states[0] = -95.071196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411772775, states[0] = -95.125166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425520810, states[0] = 20.740304, states[40]= 0.008792
Saving checkpoint... 
Iteration: 439276180, states[0] = -95.128270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453099125, states[0] = -18.308453, states[40]= 0.001094
Saving checkpoint... 
Iteration: 466586479, states[0] = -6.954983, states[40]= 0.002968
Saving checkpoint... 
Iteration: 480199832, states[0] = -95.024427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493574834, states[0] = 0.721625, states[40]= 0.004310
Saving checkpoint... 
Iteration: 507124966, states[0] = -43.613885, states[40]= 0.000077
Saving checkpoint... 
Iteration: 520746697, states[0] = -95.097181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534275112, states[0] = -95.127238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547515377, states[0] = 21.591699, states[40]= 0.017134
Saving checkpoint... 
Iteration: 560923294, states[0] = -95.198319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574466633, states[0] = -95.206180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588070887, states[0] = 2.792988, states[40]= 0.004518
Saving checkpoint... 
Iteration: 601623775, states[0] = -42.364315, states[40]= 0.000093
Saving checkpoint... 
Iteration: 615161610, states[0] = -93.248723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628691199, states[0] = -95.007319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642189643, states[0] = -95.004117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655559971, states[0] = 7.763005, states[40]= 0.004791
Saving checkpoint... 
Iteration: 669096129, states[0] = -15.463469, states[40]= 0.001400
Saving checkpoint... 
Iteration: 682645933, states[0] = -68.715977, states[40]= 0.000001
Saving checkpoint... 
Iteration: 696201127, states[0] = -95.026737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709669763, states[0] = -94.861589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723199484, states[0] = -95.023598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736832772, states[0] = -95.166976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750382786, states[0] = -95.187390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763835651, states[0] = -95.168416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777476822, states[0] = -95.207482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790952867, states[0] = -95.203864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804529446, states[0] = 18.710022, states[40]= 0.005973
Saving checkpoint... 
Iteration: 818067229, states[0] = 4.561596, states[40]= 0.004647
Saving checkpoint... 
Iteration: 831444132, states[0] = -95.202311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844852495, states[0] = -95.176128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858322779, states[0] = -95.161506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871843985, states[0] = -95.172342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885446636, states[0] = -95.202725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898969303, states[0] = -95.206352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912485924, states[0] = -95.208566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926077340, states[0] = -0.705520, states[40]= 0.004126
Saving checkpoint... 
Iteration: 939595143, states[0] = -14.536376, states[40]= 0.001526
Saving checkpoint... 
Iteration: 953211640, states[0] = -95.045564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966736299, states[0] = -95.083486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980272128, states[0] = -95.124176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993860024, states[0] = -95.179116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007466150, states[0] = -95.205817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021028489, states[0] = 18.972589, states[40]= 0.006119
Saving checkpoint... 
Iteration: 1034561114, states[0] = 7.280763, states[40]= 0.004775
Saving checkpoint... 
Iteration: 1048090277, states[0] = -10.114879, states[40]= 0.002302
Saving checkpoint... 
Iteration: 1061606414, states[0] = -25.269703, states[40]= 0.000692
Saving checkpoint... 
Iteration: 1075156389, states[0] = -87.444103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088723103, states[0] = -95.064242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102285688, states[0] = -95.135990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115822328, states[0] = -95.161077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129309306, states[0] = -95.153174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142876183, states[0] = -95.184948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156447883, states[0] = -95.202763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169977337, states[0] = -95.207287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183508523, states[0] = 23.062530, states[40]= 0.076316
Saving checkpoint... 
Iteration: 1197063902, states[0] = 6.072505, states[40]= 0.004727
Saving checkpoint... 
Iteration: 1210663249, states[0] = -93.965794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224191979, states[0] = -95.008499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237685305, states[0] = -94.994462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251277949, states[0] = -95.129302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264845264, states[0] = -95.172663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278399586, states[0] = -95.192008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291997422, states[0] = -95.209659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305523651, states[0] = 20.162088, states[40]= 0.007320
Saving checkpoint... 
Iteration: 1319061996, states[0] = 6.903664, states[40]= 0.004761
Saving checkpoint... 
Iteration: 1332600482, states[0] = -19.602897, states[40]= 0.000992
Saving checkpoint... 
Iteration: 1346189545, states[0] = -95.003436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359666801, states[0] = -94.668789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373276289, states[0] = -95.127737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386616175, states[0] = -34.701305, states[40]= 0.000273
Saving checkpoint... 
Iteration: 1400112387, states[0] = -31.011956, states[40]= 0.000423
Saving checkpoint... 
Iteration: 1413672207, states[0] = -94.924689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427078375, states[0] = -1.325209, states[40]= 0.004036
Saving checkpoint... 
Iteration: 1440446856, states[0] = -95.202390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453970299, states[0] = -95.206122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467478516, states[0] = -95.207244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481020901, states[0] = 20.723468, states[40]= 0.008728
Saving checkpoint... 
Iteration: 1494588695, states[0] = -8.760244, states[40]= 0.002583
Saving checkpoint... 
Iteration: 1508061904, states[0] = -95.383967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520913415, states[0] = -95.340315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1533779452, states[0] = -95.289041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546695357, states[0] = -95.327974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559205534, states[0] = -43.979293, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1572165134, states[0] = -95.271230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585112219, states[0] = -95.366420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598191099, states[0] = -28.123779, states[40]= 0.000549
Saving checkpoint... 
Iteration: 1611655365, states[0] = 4.588637, states[40]= 0.005296
Saving checkpoint... 
Iteration: 1625116229, states[0] = 21.573723, states[40]= 0.016499
Saving checkpoint... 
Iteration: 1638356325, states[0] = 3.997595, states[40]= 0.005245
Saving checkpoint... 
Iteration: 1651598518, states[0] = -36.532139, states[40]= 0.000214
Saving checkpoint... 
Iteration: 1664979068, states[0] = -95.441089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678615269, states[0] = -56.968292, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1692399564, states[0] = -37.740405, states[40]= 0.000182
Saving checkpoint... 
Iteration: 1706152590, states[0] = 6.129451, states[40]= 0.005422
Saving checkpoint... 
Iteration: 1719913803, states[0] = 22.159902, states[40]= 0.024558
Saving checkpoint... 
Iteration: 1733565707, states[0] = -95.279025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747297890, states[0] = -35.855162, states[40]= 0.000234
Saving checkpoint... 
Iteration: 1760938492, states[0] = -95.404672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774500339, states[0] = -53.700658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788093887, states[0] = -31.388350, states[40]= 0.000398
Saving checkpoint... 
Iteration: 1801590580, states[0] = -14.564023, states[40]= 0.001601
Saving checkpoint... 
Iteration: 1815180028, states[0] = -95.016392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1828990289, states[0] = -95.233822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842710917, states[0] = -95.061052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856442266, states[0] = -95.212484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870149256, states[0] = -75.221562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883806724, states[0] = -95.155950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897485496, states[0] = -95.211113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911203917, states[0] = -95.033346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924713390, states[0] = -95.049377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938217375, states[0] = -95.055510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951938113, states[0] = -95.201038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965703369, states[0] = -95.030467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979375376, states[0] = -95.184346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993035472, states[0] = 16.885626, states[40]= 0.005371
Saving checkpoint... 
Iteration: 2006680160, states[0] = -94.981115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020273432, states[0] = -95.124720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034006361, states[0] = 24.953934, states[40]= 0.123721
Saving checkpoint... 
Iteration: 2047703779, states[0] = -95.030753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061388085, states[0] = -95.188126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2074985607, states[0] = -95.207702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088655945, states[0] = -86.670932, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.085223
 - CaMKt in component CaMK (millimolar): 0.007107
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.505151
 - nass in component intracellular_ions (millimolar): 6.505213
 - ki in component intracellular_ions (millimolar): 145.470504
 - kss in component intracellular_ions (millimolar): 145.470483
 - cansr in component intracellular_ions (millimolar): 1.318836
 - cajsr in component intracellular_ions (millimolar): 1.280616
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003552
 - hf in component INa (dimensionless): 0.883146
 - hs in component INa (dimensionless): 0.883142
 - j in component INa (dimensionless): 0.883116
 - hsp in component INa (dimensionless): 0.731787
 - jp in component INa (dimensionless): 0.883098
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.715158
 - hLp in component INaL (dimensionless): 0.458826
 - a in component Ito (dimensionless): 0.000616
 - iF in component Ito (dimensionless): 0.999874
 - iS in component Ito (dimensionless): 0.623236
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999874
 - iSp in component Ito (dimensionless): 0.698809
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935560
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001626
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326266
 - xs1 in component IKs (dimensionless): 0.242113
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997288
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:08:01 (10072): called boinc_finish(0)

</stderr_txt>
]]>


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