𝕏

Task 55413989

Name HuVeMOp_20240630093703370580_ORdGradInc_k_25-Pueyo_APDR-conf_443_0
Workunit 26313687
Created 30 Jun 2024, 7:37:57 UTC
Sent 30 Jun 2024, 9:34:48 UTC
Report deadline 3 Jul 2024, 19:10:48 UTC
Received 2 Jul 2024, 13:52:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236478
Run time 2 hours 11 min 53 sec
CPU time 2 hours 10 min 46 sec
Validate state Valid
Credit 58.13
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093703370580_ORdGradInc_k_25-Pueyo_APDR-conf_443.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093703370580_ORdGradInc_k_25-Pueyo_APDR-conf_443_0_r1708008146_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093703370580_ORdGradInc_k_25-Pueyo_APDR-conf_443_0_r1708008146_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 117.378382
     * GNaL_b in INaL: 0.006285
     * Gto_b in Ito: 0.089328
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031242
     * GKs_b in IKs: 0.001813
     * GK1_b in IK1: 0.163689
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 74.329542
     * GKb_b in IKb: 0.003811
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.043022
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12579350, states[0] = -4.336390, states[40]= 0.003497
Saving checkpoint... 
Iteration: 24182428, states[0] = -94.826351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35348082, states[0] = -95.000518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47107931, states[0] = -26.686834, states[40]= 0.000627
Saving checkpoint... 
Iteration: 59197590, states[0] = -94.811815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71070485, states[0] = 3.062900, states[40]= 0.004536
Saving checkpoint... 
Iteration: 83570984, states[0] = 2.936364, states[40]= 0.004521
Saving checkpoint... 
Iteration: 95739608, states[0] = -94.868849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107425545, states[0] = -94.984981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119581450, states[0] = -2.651064, states[40]= 0.003794
Saving checkpoint... 
Iteration: 131777151, states[0] = -94.908048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144345328, states[0] = -94.954554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156398116, states[0] = -94.974122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168687179, states[0] = -94.766370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181074824, states[0] = 1.245114, states[40]= 0.004346
Saving checkpoint... 
Iteration: 193202245, states[0] = -94.799360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205120009, states[0] = -36.193978, states[40]= 0.000222
Saving checkpoint... 
Iteration: 217276949, states[0] = -94.905627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229511748, states[0] = 22.442895, states[40]= 0.036646
Saving checkpoint... 
Iteration: 242199297, states[0] = -94.793276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253886738, states[0] = -94.969507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265797917, states[0] = -94.923616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277931697, states[0] = -94.981395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290032712, states[0] = 17.927229, states[40]= 0.005767
Saving checkpoint... 
Iteration: 301938353, states[0] = -94.982741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313930115, states[0] = -94.981015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325924567, states[0] = -94.979773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338435376, states[0] = -94.982106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349941402, states[0] = -94.983304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361131413, states[0] = -47.558124, states[40]= 0.000041
Saving checkpoint... 
Iteration: 373438879, states[0] = -94.982791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385267649, states[0] = -94.895960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398031346, states[0] = 18.338713, states[40]= 0.005925
Saving checkpoint... 
Iteration: 410290039, states[0] = -94.917119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422115487, states[0] = -31.916181, states[40]= 0.000382
Saving checkpoint... 
Iteration: 433945263, states[0] = -94.983988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445853309, states[0] = -94.956505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458141267, states[0] = -58.238283, states[40]= 0.000007
Saving checkpoint... 
Iteration: 469838700, states[0] = -94.949447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481645209, states[0] = -62.788033, states[40]= 0.000003
Saving checkpoint... 
Iteration: 493874542, states[0] = -94.965092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505687731, states[0] = -94.767031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517690567, states[0] = -94.774530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529894760, states[0] = -94.971799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541795728, states[0] = -94.921689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553722163, states[0] = -94.834687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565726011, states[0] = -94.840968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577577313, states[0] = -0.085474, states[40]= 0.004184
Saving checkpoint... 
Iteration: 589794125, states[0] = -94.920377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601847311, states[0] = -94.953639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613980883, states[0] = -94.989550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626229916, states[0] = -94.847090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638547608, states[0] = 12.816754, states[40]= 0.004982
Saving checkpoint... 
Iteration: 650826455, states[0] = -94.942607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663224624, states[0] = -94.838668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675860406, states[0] = -94.959443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687783381, states[0] = -94.911153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699423058, states[0] = -94.979194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711547757, states[0] = 12.761855, states[40]= 0.004979
Saving checkpoint... 
Iteration: 723327941, states[0] = -94.943424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735401935, states[0] = -94.973769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747614426, states[0] = -30.925512, states[40]= 0.000427
Saving checkpoint... 
Iteration: 759862110, states[0] = -94.960101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772111280, states[0] = -28.001693, states[40]= 0.000568
Saving checkpoint... 
Iteration: 784450810, states[0] = -94.984790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796721083, states[0] = -94.832735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808748523, states[0] = -94.873323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821046627, states[0] = 13.176999, states[40]= 0.005003
Saving checkpoint... 
Iteration: 832783490, states[0] = -94.911163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844866256, states[0] = -94.961725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856827357, states[0] = -94.943006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868983780, states[0] = -94.989778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880669916, states[0] = -93.920039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892701404, states[0] = -94.796932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904993503, states[0] = -94.990963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916670127, states[0] = -93.970941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928468915, states[0] = -94.987664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940746380, states[0] = -94.870452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953223816, states[0] = -94.837172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965000910, states[0] = 49.542497, states[40]= 0.018160
Saving checkpoint... 
Iteration: 977432725, states[0] = -94.981163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989438562, states[0] = -94.982354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001459930, states[0] = -94.986214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013809626, states[0] = -94.931698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025859673, states[0] = -94.958924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037869900, states[0] = -94.963026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050173801, states[0] = -94.496235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062118430, states[0] = -34.680266, states[40]= 0.000271
Saving checkpoint... 
Iteration: 1074434397, states[0] = -94.981454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086514694, states[0] = 21.964525, states[40]= 0.020229
Saving checkpoint... 
Iteration: 1097951313, states[0] = -94.984689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109813532, states[0] = -94.934283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121757453, states[0] = -94.884129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133687827, states[0] = -94.766931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145485017, states[0] = -94.989771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157746733, states[0] = -94.870784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170280056, states[0] = -94.907814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182480482, states[0] = -94.989153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194688850, states[0] = -94.769769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207008791, states[0] = 23.372337, states[40]= 0.072120
Saving checkpoint... 
Iteration: 1218998532, states[0] = -94.991354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231200172, states[0] = -94.794315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243862987, states[0] = -94.960168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256540289, states[0] = 15.441841, states[40]= 0.005215
Saving checkpoint... 
Iteration: 1268356637, states[0] = -94.957477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280335910, states[0] = -94.947493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292518454, states[0] = 21.384058, states[40]= 0.011642
Saving checkpoint... 
Iteration: 1305013320, states[0] = 22.170897, states[40]= 0.026287
Saving checkpoint... 
Iteration: 1316966128, states[0] = -94.987006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329282108, states[0] = -94.909610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341454357, states[0] = -94.985074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354262269, states[0] = -94.889513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366808344, states[0] = -94.930593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378699381, states[0] = -94.792666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390857038, states[0] = -94.957577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403097944, states[0] = -15.681965, states[40]= 0.001360
Saving checkpoint... 
Iteration: 1414914522, states[0] = -94.976707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426660097, states[0] = -84.941259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438403288, states[0] = -94.973723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450389885, states[0] = -94.969736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462169978, states[0] = -93.934779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474999622, states[0] = -94.991322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487266005, states[0] = -94.893534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499291446, states[0] = -94.917633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511860621, states[0] = -95.010489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523562785, states[0] = -95.038576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536185418, states[0] = -95.109440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548163954, states[0] = -95.063215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560271314, states[0] = -95.242440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572253554, states[0] = -95.229437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584332603, states[0] = 16.216033, states[40]= 0.006742
Saving checkpoint... 
Iteration: 1597240039, states[0] = 12.847701, states[40]= 0.006056
Saving checkpoint... 
Iteration: 1609943980, states[0] = -93.543856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622554198, states[0] = -94.999342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635063009, states[0] = 0.276598, states[40]= 0.004790
Saving checkpoint... 
Iteration: 1647745330, states[0] = -94.080095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660483428, states[0] = -95.262047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673320059, states[0] = -95.194874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686050208, states[0] = 7.734679, states[40]= 0.005546
Saving checkpoint... 
Iteration: 1698654031, states[0] = 5.669219, states[40]= 0.005380
Saving checkpoint... 
Iteration: 1711230855, states[0] = 16.891303, states[40]= 0.006985
Saving checkpoint... 
Iteration: 1723591333, states[0] = -26.722644, states[40]= 0.000620
Saving checkpoint... 
Iteration: 1735778267, states[0] = -95.258421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748107570, states[0] = 25.346691, states[40]= 0.089803
Saving checkpoint... 
Iteration: 1760254544, states[0] = -95.008667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772921583, states[0] = -95.197265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786330587, states[0] = -74.745551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798770440, states[0] = -95.252047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811536261, states[0] = 16.164002, states[40]= 0.005421
Saving checkpoint... 
Iteration: 1824051598, states[0] = 10.737896, states[40]= 0.004931
Saving checkpoint... 
Iteration: 1836080732, states[0] = -2.915122, states[40]= 0.003769
Saving checkpoint... 
Iteration: 1848396055, states[0] = -94.987864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861115501, states[0] = -32.603856, states[40]= 0.000352
Saving checkpoint... 
Iteration: 1873952258, states[0] = -94.991898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886750224, states[0] = -94.880020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899862008, states[0] = -94.962764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912176562, states[0] = -94.651459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924562996, states[0] = 6.750598, states[40]= 0.004755
Saving checkpoint... 
Iteration: 1936133607, states[0] = -49.960842, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1947966968, states[0] = -94.987502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960062919, states[0] = 6.805556, states[40]= 0.004757
Saving checkpoint... 
Iteration: 1972215739, states[0] = -94.823184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984059620, states[0] = 8.180351, states[40]= 0.004811
Saving checkpoint... 
Iteration: 1995787298, states[0] = -94.913957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008067321, states[0] = 4.891847, states[40]= 0.004656
Saving checkpoint... 
Iteration: 2020024477, states[0] = 20.170288, states[40]= 0.007367
Saving checkpoint... 
Iteration: 2032003521, states[0] = 34.375534, states[40]= 0.139854
Saving checkpoint... 
Iteration: 2043788010, states[0] = -94.914396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055909452, states[0] = -94.974998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067956768, states[0] = -94.985016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079959513, states[0] = -94.985458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092073181, states[0] = 2.104296, states[40]= 0.004435
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.866819
 - CaMKt in component CaMK (millimolar): 0.006912
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.512632
 - nass in component intracellular_ions (millimolar): 6.512692
 - ki in component intracellular_ions (millimolar): 145.467363
 - kss in component intracellular_ions (millimolar): 145.467343
 - cansr in component intracellular_ions (millimolar): 1.302536
 - cajsr in component intracellular_ions (millimolar): 1.264321
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003631
 - hf in component INa (dimensionless): 0.879392
 - hs in component INa (dimensionless): 0.879387
 - j in component INa (dimensionless): 0.879359
 - hsp in component INa (dimensionless): 0.724684
 - jp in component INa (dimensionless): 0.879340
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708375
 - hLp in component INaL (dimensionless): 0.449106
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.618262
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.692507
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934027
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999880
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001561
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.338910
 - xs1 in component IKs (dimensionless): 0.245501
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997346
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:51:56 (7157): called boinc_finish(0)

</stderr_txt>
]]>


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