𝕏

Task 55412957

Name HuVeMOp_20240630093703370580_ORdGradInc_k_25-Pueyo_APDR-conf_11_0
Workunit 26313172
Created 30 Jun 2024, 7:37:20 UTC
Sent 30 Jun 2024, 9:27:36 UTC
Report deadline 3 Jul 2024, 19:03:36 UTC
Received 30 Jun 2024, 11:56:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 28 min 32 sec
CPU time 2 hours 26 min 24 sec
Validate state Valid
Credit 61.33
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093703370580_ORdGradInc_k_25-Pueyo_APDR-conf_11.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093703370580_ORdGradInc_k_25-Pueyo_APDR-conf_11_0_r544934091_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093703370580_ORdGradInc_k_25-Pueyo_APDR-conf_11_0_r544934091_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.795903
     * GNaL_b in INaL: 0.005234
     * Gto_b in Ito: 0.082410
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033663
     * GKs_b in IKs: 0.002044
     * GK1_b in IK1: 0.166693
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.180862
     * GKb_b in IKb: 0.003836
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045710
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14808186, states[0] = -95.030666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29629101, states[0] = -59.134539, states[40]= 0.000005
Saving checkpoint... 
Iteration: 44376664, states[0] = -95.018854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59302511, states[0] = -94.974688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74227720, states[0] = -94.894295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89085625, states[0] = -11.350680, states[40]= 0.002087
Saving checkpoint... 
Iteration: 103611005, states[0] = -36.640227, states[40]= 0.000187
Saving checkpoint... 
Iteration: 118385662, states[0] = -94.999310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133664309, states[0] = -94.636601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148918605, states[0] = -95.006102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164197253, states[0] = -94.834179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179441368, states[0] = -95.009905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194691228, states[0] = -94.822202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209899548, states[0] = -95.000575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224682604, states[0] = -94.804545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239091781, states[0] = -16.997737, states[40]= 0.001219
Saving checkpoint... 
Iteration: 254049520, states[0] = 10.275749, states[40]= 0.005014
Saving checkpoint... 
Iteration: 268868382, states[0] = -94.990921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283385409, states[0] = -94.996416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297951253, states[0] = -95.011063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312274189, states[0] = -94.936704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326836969, states[0] = -94.978005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341326447, states[0] = -94.972737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355755849, states[0] = -94.918738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369941969, states[0] = -95.009447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384863827, states[0] = -94.989189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399372325, states[0] = -94.992171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414128407, states[0] = -55.273658, states[40]= 0.000010
Saving checkpoint... 
Iteration: 428278163, states[0] = -94.940089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442586849, states[0] = -12.160694, states[40]= 0.001932
Saving checkpoint... 
Iteration: 457120577, states[0] = -46.486049, states[40]= 0.000043
Saving checkpoint... 
Iteration: 471630513, states[0] = -57.711588, states[40]= 0.000007
Saving checkpoint... 
Iteration: 485808262, states[0] = -94.962179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499631029, states[0] = -58.316009, states[40]= 0.000006
Saving checkpoint... 
Iteration: 513466278, states[0] = -95.013181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527371696, states[0] = -94.991884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541190821, states[0] = -94.820907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554861328, states[0] = -94.988165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568417697, states[0] = -95.004545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581966294, states[0] = -95.013144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595704557, states[0] = -94.846515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609490761, states[0] = -95.016178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623338518, states[0] = -94.978558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637343731, states[0] = -94.980926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651661574, states[0] = -94.429876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666328634, states[0] = -94.973685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680692854, states[0] = -94.824779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695504897, states[0] = 28.707321, states[40]= 0.140848
Saving checkpoint... 
Iteration: 710016744, states[0] = 21.280629, states[40]= 0.014598
Saving checkpoint... 
Iteration: 724441959, states[0] = -95.009241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738833664, states[0] = -94.976169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753293782, states[0] = -94.952219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767755191, states[0] = -94.917790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782191262, states[0] = -94.821630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796602425, states[0] = -27.680293, states[40]= 0.000527
Saving checkpoint... 
Iteration: 810986223, states[0] = -95.015550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825489286, states[0] = -95.015890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840250665, states[0] = -94.912741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854926826, states[0] = -95.006310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869886145, states[0] = -94.996278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884497715, states[0] = -95.016764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899257327, states[0] = -94.919997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914091718, states[0] = -16.929865, states[40]= 0.001226
Saving checkpoint... 
Iteration: 929422100, states[0] = -95.005290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944603400, states[0] = -28.661426, states[40]= 0.000482
Saving checkpoint... 
Iteration: 959645407, states[0] = -78.364971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974709259, states[0] = -94.854467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989750045, states[0] = -94.911951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005162050, states[0] = -94.477259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020457773, states[0] = -95.011654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035873164, states[0] = -94.992088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051316018, states[0] = -94.966552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066525974, states[0] = 18.982467, states[40]= 0.007104
Saving checkpoint... 
Iteration: 1081402954, states[0] = -95.000766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096355799, states[0] = -94.985724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111224894, states[0] = -94.879192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126072984, states[0] = -1.208721, states[40]= 0.004097
Saving checkpoint... 
Iteration: 1141021250, states[0] = 20.262829, states[40]= 0.009146
Saving checkpoint... 
Iteration: 1155917414, states[0] = -95.004147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170697299, states[0] = -94.832951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185590129, states[0] = -15.350154, states[40]= 0.001423
Saving checkpoint... 
Iteration: 1200461275, states[0] = -95.012073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215412289, states[0] = -95.002952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230472230, states[0] = -95.013580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245561154, states[0] = 5.136399, states[40]= 0.004752
Saving checkpoint... 
Iteration: 1260203365, states[0] = -94.844010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275044468, states[0] = 12.345674, states[40]= 0.005155
Saving checkpoint... 
Iteration: 1289784013, states[0] = -94.944438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304479996, states[0] = -95.014526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319184312, states[0] = -94.807385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333921327, states[0] = -95.004894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348611622, states[0] = -36.998359, states[40]= 0.000178
Saving checkpoint... 
Iteration: 1363298200, states[0] = -94.955014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377948640, states[0] = -95.010005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392591697, states[0] = -16.908642, states[40]= 0.001229
Saving checkpoint... 
Iteration: 1407235920, states[0] = -94.894385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421961468, states[0] = -95.011974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436795480, states[0] = -94.953052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451512245, states[0] = 22.229326, states[40]= 0.032230
Saving checkpoint... 
Iteration: 1466151564, states[0] = -88.736693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481005058, states[0] = 28.270648, states[40]= 0.138919
Saving checkpoint... 
Iteration: 1495850840, states[0] = -94.983487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510693245, states[0] = -95.134508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525557950, states[0] = 1.467847, states[40]= 0.004968
Saving checkpoint... 
Iteration: 1540557665, states[0] = 1.354269, states[40]= 0.004968
Saving checkpoint... 
Iteration: 1555363083, states[0] = -95.103779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570350210, states[0] = -95.064595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585190502, states[0] = -95.283155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599579573, states[0] = -95.277686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614379942, states[0] = -20.994426, states[40]= 0.000944
Saving checkpoint... 
Iteration: 1629200141, states[0] = -95.191103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643939397, states[0] = -95.244757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658691891, states[0] = -95.288228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673505238, states[0] = -51.020599, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1688221937, states[0] = -74.624278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702969226, states[0] = -95.130832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717455685, states[0] = -95.261454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731768199, states[0] = -95.128489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746097226, states[0] = -41.178500, states[40]= 0.000101
Saving checkpoint... 
Iteration: 1760453824, states[0] = 3.399979, states[40]= 0.005233
Saving checkpoint... 
Iteration: 1774682315, states[0] = -95.159222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789118776, states[0] = -95.220288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803665914, states[0] = -94.790483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818310831, states[0] = -95.001645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833257796, states[0] = -94.945658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848072605, states[0] = -1.507507, states[40]= 0.004065
Saving checkpoint... 
Iteration: 1862994455, states[0] = -95.026395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877880282, states[0] = -95.000680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892621284, states[0] = -47.580088, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1907385444, states[0] = -94.998279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922145538, states[0] = -78.826394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936910512, states[0] = -95.003270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951952590, states[0] = -95.011036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966683710, states[0] = -94.806217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981344769, states[0] = -94.980891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995761572, states[0] = -94.923925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010074830, states[0] = -2.398007, states[40]= 0.003905
Saving checkpoint... 
Iteration: 2024504931, states[0] = 28.611950, states[40]= 0.140474
Saving checkpoint... 
Iteration: 2039017530, states[0] = 21.115165, states[40]= 0.013158
Saving checkpoint... 
Iteration: 2053523375, states[0] = 19.714223, states[40]= 0.007996
Saving checkpoint... 
Iteration: 2068201279, states[0] = -94.839757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082771855, states[0] = -94.933547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097389241, states[0] = -94.996442, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.892140
 - CaMKt in component CaMK (millimolar): 0.006574
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.629491
 - nass in component intracellular_ions (millimolar): 6.629549
 - ki in component intracellular_ions (millimolar): 145.353364
 - kss in component intracellular_ions (millimolar): 145.353345
 - cansr in component intracellular_ions (millimolar): 1.290317
 - cajsr in component intracellular_ions (millimolar): 1.253468
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003622
 - hf in component INa (dimensionless): 0.879832
 - hs in component INa (dimensionless): 0.879828
 - j in component INa (dimensionless): 0.879803
 - hsp in component INa (dimensionless): 0.725516
 - jp in component INa (dimensionless): 0.879786
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.711562
 - hLp in component INaL (dimensionless): 0.457519
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.629240
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.705866
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940793
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999904
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001519
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.320355
 - xs1 in component IKs (dimensionless): 0.228794
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997340
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:56:12 (594388): called boinc_finish(0)

</stderr_txt>
]]>