𝕏

Task 55412489

Name HuVeMOp_20240630093549983651_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_191_0
Workunit 26312938
Created 30 Jun 2024, 7:37:00 UTC
Sent 30 Jun 2024, 9:21:36 UTC
Report deadline 3 Jul 2024, 12:14:24 UTC
Received 1 Jul 2024, 16:38:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 225785
Run time 1 hours 52 min 52 sec
CPU time 1 hours 42 min 43 sec
Validate state Valid
Credit 47.12
Device peak FLOPS 3.23 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 5.30 MB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093549983651_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_191.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093549983651_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_191_0_r824675719_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093549983651_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_191_0_r824675719_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.926477
     * GNaL_b in INaL: 0.005944
     * Gto_b in Ito: 0.099143
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033781
     * GKs_b in IKs: 0.000091
     * GK1_b in IK1: 0.173229
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 66.682424
     * GKb_b in IKb: 0.003757
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025322
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10242633, states[0] = -94.707434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18403508, states[0] = -94.869712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28183632, states[0] = -94.340922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37608421, states[0] = -17.617881, states[40]= 0.001432
Saving checkpoint... 
Iteration: 47711794, states[0] = -94.526234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55831620, states[0] = -94.801182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65974146, states[0] = -94.885590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74250638, states[0] = -94.657645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84256845, states[0] = -94.674514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92621209, states[0] = -30.215075, states[40]= 0.001031
Saving checkpoint... 
Iteration: 102555885, states[0] = 15.700235, states[40]= 0.002404
Saving checkpoint... 
Iteration: 110892086, states[0] = -94.854689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118940851, states[0] = -94.877854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128569308, states[0] = 10.052778, states[40]= 0.003514
Saving checkpoint... 
Iteration: 138329735, states[0] = -94.802687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146666276, states[0] = -84.491005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156509724, states[0] = 26.321110, states[40]= 0.056921
Saving checkpoint... 
Iteration: 166741389, states[0] = -94.633437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176784351, states[0] = -94.735956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183809443, states[0] = -94.776883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194040902, states[0] = 21.139487, states[40]= 0.001395
Saving checkpoint... 
Iteration: 204110262, states[0] = -19.788304, states[40]= 0.001305
Saving checkpoint... 
Iteration: 211903176, states[0] = -94.861377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221762803, states[0] = -94.690463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231786684, states[0] = -94.740087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239991850, states[0] = -94.892367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249572615, states[0] = 8.490845, states[40]= 0.003763
Saving checkpoint... 
Iteration: 257475099, states[0] = -94.888390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267203250, states[0] = -94.493978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275643476, states[0] = -53.181576, states[40]= 0.000064
Saving checkpoint... 
Iteration: 283916104, states[0] = -94.867540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293375457, states[0] = -94.843879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301942620, states[0] = -94.878337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311635888, states[0] = -44.972386, states[40]= 0.000209
Saving checkpoint... 
Iteration: 320133092, states[0] = -42.059305, states[40]= 0.000307
Saving checkpoint... 
Iteration: 330240248, states[0] = -94.629365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338633548, states[0] = -42.529582, states[40]= 0.000289
Saving checkpoint... 
Iteration: 348702587, states[0] = -94.490709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357943379, states[0] = -94.878333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367919516, states[0] = -94.868701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376636516, states[0] = -45.635856, states[40]= 0.000191
Saving checkpoint... 
Iteration: 386471048, states[0] = -94.886712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394798221, states[0] = -94.759008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404583903, states[0] = 2.440958, states[40]= 0.004295
Saving checkpoint... 
Iteration: 413000818, states[0] = 44.168670, states[40]= 0.092124
Saving checkpoint... 
Iteration: 422802840, states[0] = -94.766090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431435860, states[0] = -94.875200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441322016, states[0] = -94.792412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450974567, states[0] = -94.887311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459430831, states[0] = -94.873086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467646336, states[0] = -56.371558, states[40]= 0.000039
Saving checkpoint... 
Iteration: 477076130, states[0] = 6.746946, states[40]= 0.003997
Saving checkpoint... 
Iteration: 485510322, states[0] = 26.367769, states[40]= 0.046486
Saving checkpoint... 
Iteration: 495120763, states[0] = -29.881719, states[40]= 0.001048
Saving checkpoint... 
Iteration: 504811674, states[0] = -94.778528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513189786, states[0] = -94.424123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521589244, states[0] = -1.016827, states[40]= 0.004178
Saving checkpoint... 
Iteration: 531339894, states[0] = -94.812175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541464032, states[0] = -94.884013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549503492, states[0] = 33.630314, states[40]= 0.448193
Saving checkpoint... 
Iteration: 559226827, states[0] = -94.584505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567489842, states[0] = -94.890338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577238707, states[0] = -94.623420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585577214, states[0] = 6.186836, states[40]= 0.004060
Saving checkpoint... 
Iteration: 595165108, states[0] = -82.511487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 603194907, states[0] = -94.454189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613158431, states[0] = -71.492401, states[40]= 0.000003
Saving checkpoint... 
Iteration: 621602945, states[0] = -12.636612, states[40]= 0.002075
Saving checkpoint... 
Iteration: 630548237, states[0] = 18.559695, states[40]= 0.001832
Saving checkpoint... 
Iteration: 639966534, states[0] = -94.884232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649418449, states[0] = -94.866824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659021178, states[0] = 26.333905, states[40]= 0.001811
Saving checkpoint... 
Iteration: 668498729, states[0] = -94.891677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677817700, states[0] = -94.785757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687377287, states[0] = -94.843220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697230954, states[0] = -94.597915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706525363, states[0] = 25.599120, states[40]= 0.001065
Saving checkpoint... 
Iteration: 716231846, states[0] = -94.600789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725669402, states[0] = -89.188193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734870404, states[0] = -94.838013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744538959, states[0] = 21.787971, states[40]= 0.001299
Saving checkpoint... 
Iteration: 754024242, states[0] = 25.824915, states[40]= 0.001160
Saving checkpoint... 
Iteration: 763413604, states[0] = -94.863987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772830971, states[0] = -94.801367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782641606, states[0] = -51.121264, states[40]= 0.000087
Saving checkpoint... 
Iteration: 792413012, states[0] = -94.863558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802094526, states[0] = -5.011769, states[40]= 0.003627
Saving checkpoint... 
Iteration: 811782554, states[0] = -94.729545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821036103, states[0] = 22.707458, states[40]= 0.001173
Saving checkpoint... 
Iteration: 830676257, states[0] = -93.640447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840463385, states[0] = -94.882350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849846220, states[0] = -94.816884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859679441, states[0] = -94.118959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869202997, states[0] = -94.489866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878722102, states[0] = -94.566021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888131751, states[0] = -40.683871, states[40]= 0.000366
Saving checkpoint... 
Iteration: 897577755, states[0] = 5.903577, states[40]= 0.004089
Saving checkpoint... 
Iteration: 907253793, states[0] = -94.664657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914983166, states[0] = -94.887119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924859273, states[0] = -94.828246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934425464, states[0] = -94.868512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943654799, states[0] = -66.473317, states[40]= 0.000008
Saving checkpoint... 
Iteration: 952761084, states[0] = -94.682745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962152785, states[0] = -63.921328, states[40]= 0.000011
Saving checkpoint... 
Iteration: 970501901, states[0] = 44.101363, states[40]= 0.485241
Saving checkpoint... 
Iteration: 978365209, states[0] = -94.832814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986525763, states[0] = 25.514514, states[40]= 0.001042
Saving checkpoint... 
Iteration: 995055041, states[0] = 16.009041, states[40]= 0.002332
Saving checkpoint... 
Iteration: 1004738998, states[0] = -94.622176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014759458, states[0] = -94.678478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023042229, states[0] = 20.687460, states[40]= 0.001466
Saving checkpoint... 
Iteration: 1032420414, states[0] = -94.865820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040397609, states[0] = -94.854261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050137660, states[0] = -46.849103, states[40]= 0.000161
Saving checkpoint... 
Iteration: 1058665549, states[0] = -83.270681, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1066671930, states[0] = -91.681627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076374482, states[0] = -94.839310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084679134, states[0] = -94.088686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094621744, states[0] = -30.822944, states[40]= 0.000990
Saving checkpoint... 
Iteration: 1104239272, states[0] = -94.622519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112397999, states[0] = -94.854125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122098305, states[0] = -8.270616, states[40]= 0.002961
Saving checkpoint... 
Iteration: 1131630797, states[0] = -39.715589, states[40]= 0.000412
Saving checkpoint... 
Iteration: 1141591937, states[0] = -2.971191, states[40]= 0.003959
Saving checkpoint... 
Iteration: 1151138504, states[0] = -47.752991, states[40]= 0.000142
Saving checkpoint... 
Iteration: 1160687385, states[0] = -94.398936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170378637, states[0] = -94.841763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180048270, states[0] = 18.548590, states[40]= 0.001834
Saving checkpoint... 
Iteration: 1189862599, states[0] = -94.829677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199727587, states[0] = -94.583936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208240534, states[0] = -94.625839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216466770, states[0] = -94.881449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226039641, states[0] = 21.563000, states[40]= 0.001332
Saving checkpoint... 
Iteration: 1234187650, states[0] = -94.401439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243672287, states[0] = -91.936396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253178009, states[0] = -93.955655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262819609, states[0] = -94.785308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270969870, states[0] = -94.882027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280513702, states[0] = 26.670272, states[40]= 0.014992
Saving checkpoint... 
Iteration: 1290254933, states[0] = -94.665707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298413056, states[0] = -94.861076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306619058, states[0] = -28.241684, states[40]= 0.001134
Saving checkpoint... 
Iteration: 1316438568, states[0] = -94.871847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324631872, states[0] = -40.804688, states[40]= 0.000360
Saving checkpoint... 
Iteration: 1334330813, states[0] = -94.798403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342557596, states[0] = 15.009448, states[40]= 0.002538
Saving checkpoint... 
Iteration: 1350786492, states[0] = -94.734195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360629344, states[0] = -38.255524, states[40]= 0.000490
Saving checkpoint... 
Iteration: 1369030344, states[0] = 24.397386, states[40]= 0.000996
Saving checkpoint... 
Iteration: 1377497980, states[0] = -94.888027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387667654, states[0] = -86.741802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396357280, states[0] = -94.824219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406352946, states[0] = -94.820371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414961317, states[0] = -94.878909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424985965, states[0] = -94.885242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433220741, states[0] = -94.558230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441477339, states[0] = -94.883115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451601175, states[0] = -10.934132, states[40]= 0.002399
Saving checkpoint... 
Iteration: 1460180610, states[0] = -94.204018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470114317, states[0] = -23.701372, states[40]= 0.001238
Saving checkpoint... 
Iteration: 1478561523, states[0] = 13.420002, states[40]= 0.002866
Saving checkpoint... 
Iteration: 1488398473, states[0] = -94.852532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497331928, states[0] = -94.798847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505742379, states[0] = -95.288580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515814108, states[0] = -32.588612, states[40]= 0.001149
Saving checkpoint... 
Iteration: 1525686747, states[0] = -94.890365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534135026, states[0] = -94.867918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543998212, states[0] = -94.472317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550959204, states[0] = -94.743771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560787948, states[0] = -94.693915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1569129577, states[0] = -28.728544, states[40]= 0.001231
Saving checkpoint... 
Iteration: 1579088758, states[0] = 3.826364, states[40]= 0.004105
Saving checkpoint... 
Iteration: 1587396546, states[0] = -94.580011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1597257217, states[0] = -94.580675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605581899, states[0] = 8.658451, states[40]= 0.003869
Saving checkpoint... 
Iteration: 1613821773, states[0] = -94.567727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623847607, states[0] = -94.494950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632177041, states[0] = -94.479572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642082678, states[0] = -94.474079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650336195, states[0] = -94.336459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659907258, states[0] = -94.464039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667690748, states[0] = -79.824701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1676989654, states[0] = -94.461657, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.333802
 - CaMKt in component CaMK (millimolar): 0.001187
 - cass in component intracellular_ions (millimolar): 0.000089
 - nai in component intracellular_ions (millimolar): 6.533765
 - nass in component intracellular_ions (millimolar): 6.533855
 - ki in component intracellular_ions (millimolar): 145.346002
 - kss in component intracellular_ions (millimolar): 145.345990
 - cansr in component intracellular_ions (millimolar): 1.606227
 - cajsr in component intracellular_ions (millimolar): 1.606306
 - cai in component intracellular_ions (millimolar): 0.000092
 - m in component INa (dimensionless): 0.003832
 - hf in component INa (dimensionless): 0.869788
 - hs in component INa (dimensionless): 0.869788
 - j in component INa (dimensionless): 0.869789
 - hsp in component INa (dimensionless): 0.706896
 - jp in component INa (dimensionless): 0.869790
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.713936
 - hLp in component INaL (dimensionless): 0.521566
 - a in component Ito (dimensionless): 0.000648
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.997762
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.999259
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998876
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003293
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001745
 - xs1 in component IKs (dimensionless): 0.022831
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997482
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:31:58 (18328): called boinc_finish(0)

</stderr_txt>
]]>


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