𝕏

Task 55412385

Name HuVeMOp_20240630093549983651_ORdGradInc_k_25-Pueyo_APDR-conf_682_1
Workunit 26312886
Created 30 Jun 2024, 7:36:54 UTC
Sent 30 Jun 2024, 9:20:22 UTC
Report deadline 3 Jul 2024, 18:56:22 UTC
Received 30 Jun 2024, 21:44:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 190411
Run time 2 hours 46 min 11 sec
CPU time 2 hours 45 min 38 sec
Validate state Valid
Credit 62.34
Device peak FLOPS 2.89 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.64 MB
Peak swap size 6.21 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.16.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093549983651_ORdGradInc_k_25-Pueyo_APDR-conf_682.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093549983651_ORdGradInc_k_25-Pueyo_APDR-conf_682_1_r2064532774_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093549983651_ORdGradInc_k_25-Pueyo_APDR-conf_682_1_r2064532774_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 94.431715
     * GNaL_b in INaL: 0.006554
     * Gto_b in Ito: 0.075694
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.029830
     * GKs_b in IKs: 0.002119
     * GK1_b in IK1: 0.160027
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 73.433859
     * GKb_b in IKb: 0.003869
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025547
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11699175, states[0] = -94.805944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23353003, states[0] = -94.931728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34948840, states[0] = -94.939207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46868619, states[0] = -94.900349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59230282, states[0] = -94.765887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70926347, states[0] = -94.902081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82464454, states[0] = -94.905409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94052828, states[0] = 11.588183, states[40]= 0.005005
Saving checkpoint... 
Iteration: 105708502, states[0] = -94.709677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117335293, states[0] = -94.855044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128632708, states[0] = -44.691264, states[40]= 0.000067
Saving checkpoint... 
Iteration: 140061758, states[0] = 8.134595, states[40]= 0.004881
Saving checkpoint... 
Iteration: 151647049, states[0] = -59.331984, states[40]= 0.000006
Saving checkpoint... 
Iteration: 163262028, states[0] = -94.789411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174873216, states[0] = -94.870399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186448919, states[0] = -94.892134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198148529, states[0] = -60.873843, states[40]= 0.000004
Saving checkpoint... 
Iteration: 209719756, states[0] = -94.725424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221335765, states[0] = -94.851633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233281799, states[0] = -94.810229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245973246, states[0] = -94.896037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258453669, states[0] = -94.892596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270847507, states[0] = -94.857910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283686445, states[0] = -94.626877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296482656, states[0] = -94.897371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308990521, states[0] = -94.898457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321802279, states[0] = -94.828417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334072257, states[0] = 3.558071, states[40]= 0.004609
Saving checkpoint... 
Iteration: 346650727, states[0] = -63.322569, states[40]= 0.000003
Saving checkpoint... 
Iteration: 359348139, states[0] = -94.858148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372132459, states[0] = -44.275040, states[40]= 0.000071
Saving checkpoint... 
Iteration: 384863202, states[0] = -94.865347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397897799, states[0] = -94.878477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410683962, states[0] = -94.583776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423761790, states[0] = -94.787999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436620743, states[0] = -33.427861, states[40]= 0.000336
Saving checkpoint... 
Iteration: 449215066, states[0] = -94.716483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462092948, states[0] = -9.137776, states[40]= 0.002484
Saving checkpoint... 
Iteration: 474854850, states[0] = -94.861420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488019372, states[0] = 22.524125, states[40]= 0.010481
Saving checkpoint... 
Iteration: 501389577, states[0] = -94.875669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514479775, states[0] = -94.896800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527475397, states[0] = -94.896126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540240938, states[0] = -94.759791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553301841, states[0] = -94.827916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566396117, states[0] = -94.877831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579320924, states[0] = -94.841988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592009283, states[0] = 24.751670, states[40]= 0.060241
Saving checkpoint... 
Iteration: 605019855, states[0] = 22.423345, states[40]= 0.010025
Saving checkpoint... 
Iteration: 618533361, states[0] = 18.734506, states[40]= 0.005808
Saving checkpoint... 
Iteration: 631429964, states[0] = -94.887260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644600584, states[0] = -15.617801, states[40]= 0.001377
Saving checkpoint... 
Iteration: 657593871, states[0] = -9.882642, states[40]= 0.002330
Saving checkpoint... 
Iteration: 670180071, states[0] = -94.414046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682837256, states[0] = -94.852047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695452827, states[0] = -94.892119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708375095, states[0] = -94.870161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721369908, states[0] = -94.868038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734140706, states[0] = -52.546586, states[40]= 0.000019
Saving checkpoint... 
Iteration: 747118431, states[0] = -31.368272, states[40]= 0.000430
Saving checkpoint... 
Iteration: 747533884, states[0] = 18.563852, states[40]= 0.005757
Saving checkpoint... 
Iteration: 760230618, states[0] = -94.743504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773133321, states[0] = -45.115031, states[40]= 0.000062
Saving checkpoint... 
Iteration: 786239676, states[0] = -94.757750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799004357, states[0] = 31.417181, states[40]= 0.147105
Saving checkpoint... 
Iteration: 811808588, states[0] = -94.833050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824997245, states[0] = -94.899012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837907191, states[0] = -94.881101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850918815, states[0] = -94.884334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863888153, states[0] = -94.874955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877344435, states[0] = -94.855895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890440249, states[0] = -94.889438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902723482, states[0] = -94.731351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915448262, states[0] = -94.891092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928031161, states[0] = 19.434485, states[40]= 0.006056
Saving checkpoint... 
Iteration: 940977092, states[0] = -94.896141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953845708, states[0] = -94.856524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966613384, states[0] = -26.905238, states[40]= 0.000658
Saving checkpoint... 
Iteration: 979479997, states[0] = -94.896556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992432566, states[0] = -94.887656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005505276, states[0] = 28.932483, states[40]= 0.135661
Saving checkpoint... 
Iteration: 1018415336, states[0] = -94.883301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031427879, states[0] = -94.886521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044237960, states[0] = -94.754984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057100041, states[0] = -15.140466, states[40]= 0.001437
Saving checkpoint... 
Iteration: 1070064917, states[0] = 6.847881, states[40]= 0.004822
Saving checkpoint... 
Iteration: 1082989023, states[0] = -94.897780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095380185, states[0] = -94.871906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108380325, states[0] = -94.871952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120817309, states[0] = -94.839196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133212222, states[0] = -94.710745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146265039, states[0] = -94.791446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159355345, states[0] = -94.861249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172121735, states[0] = -34.315587, states[40]= 0.000300
Saving checkpoint... 
Iteration: 1185026092, states[0] = 20.915554, states[40]= 0.006975
Saving checkpoint... 
Iteration: 1197928247, states[0] = -94.886510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211071985, states[0] = 3.687019, states[40]= 0.004620
Saving checkpoint... 
Iteration: 1224012394, states[0] = 23.843526, states[40]= 0.030235
Saving checkpoint... 
Iteration: 1237078482, states[0] = 0.422881, states[40]= 0.004282
Saving checkpoint... 
Iteration: 1250395104, states[0] = -94.877090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263328197, states[0] = -94.846286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276481176, states[0] = -94.896553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289594635, states[0] = -10.509317, states[40]= 0.002204
Saving checkpoint... 
Iteration: 1302082636, states[0] = -1.934701, states[40]= 0.003935
Saving checkpoint... 
Iteration: 1315027576, states[0] = 20.503224, states[40]= 0.006636
Saving checkpoint... 
Iteration: 1327984922, states[0] = -94.897063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341253037, states[0] = -94.776338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354017377, states[0] = 22.918090, states[40]= 0.013062
Saving checkpoint... 
Iteration: 1367128532, states[0] = -40.528971, states[40]= 0.000125
Saving checkpoint... 
Iteration: 1380413898, states[0] = -94.882690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393225810, states[0] = -94.735073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406183240, states[0] = -94.564083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419062030, states[0] = 8.058636, states[40]= 0.004876
Saving checkpoint... 
Iteration: 1432325471, states[0] = -94.844460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445291552, states[0] = -94.818596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458005786, states[0] = 27.937678, states[40]= 0.125839
Saving checkpoint... 
Iteration: 1471286205, states[0] = -94.813642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484505842, states[0] = 27.841573, states[40]= 0.124687
Saving checkpoint... 
Iteration: 1497851708, states[0] = -94.859270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510632488, states[0] = -66.075949, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1523863153, states[0] = -94.906342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536694181, states[0] = -25.547886, states[40]= 0.000708
Saving checkpoint... 
Iteration: 1549997040, states[0] = -95.040504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562881327, states[0] = -95.010922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575822557, states[0] = -95.094292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589160919, states[0] = 2.814412, states[40]= 0.005151
Saving checkpoint... 
Iteration: 1602151041, states[0] = -94.046449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615480217, states[0] = -95.165130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628382706, states[0] = -95.167731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641746594, states[0] = -91.809119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1654903033, states[0] = -35.612459, states[40]= 0.000250
Saving checkpoint... 
Iteration: 1668093635, states[0] = -26.044741, states[40]= 0.000682
Saving checkpoint... 
Iteration: 1681322082, states[0] = -56.698296, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1694153398, states[0] = 6.961009, states[40]= 0.005532
Saving checkpoint... 
Iteration: 1707231567, states[0] = -95.113634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720217934, states[0] = 22.538436, states[40]= 0.013684
Saving checkpoint... 
Iteration: 1733083527, states[0] = -95.169361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746142347, states[0] = -86.605569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759023587, states[0] = -58.508101, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1772124091, states[0] = 20.473818, states[40]= 0.008750
Saving checkpoint... 
Iteration: 1785209014, states[0] = -95.077701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797985544, states[0] = -17.790503, states[40]= 0.001269
Saving checkpoint... 
Iteration: 1810282585, states[0] = -94.855234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822903960, states[0] = -94.913378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835479379, states[0] = -94.919481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847547442, states[0] = 13.506056, states[40]= 0.005097
Saving checkpoint... 
Iteration: 1859655166, states[0] = -69.807601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1871908161, states[0] = -94.888604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884009797, states[0] = 24.513117, states[40]= 0.053545
Saving checkpoint... 
Iteration: 1896632204, states[0] = -44.267535, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1909332785, states[0] = -94.851221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921717962, states[0] = -94.722660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934044456, states[0] = 14.841749, states[40]= 0.005165
Saving checkpoint... 
Iteration: 1946607595, states[0] = -21.852868, states[40]= 0.000891
Saving checkpoint... 
Iteration: 1959008328, states[0] = 25.239004, states[40]= 0.074928
Saving checkpoint... 
Iteration: 1971618659, states[0] = -31.592296, states[40]= 0.000419
Saving checkpoint... 
Iteration: 1984371453, states[0] = -94.868144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996868005, states[0] = -94.866609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009461507, states[0] = -94.893013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022085478, states[0] = -3.713463, states[40]= 0.003617
Saving checkpoint... 
Iteration: 2034681447, states[0] = -94.495636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047241928, states[0] = -94.760346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059772759, states[0] = -94.799604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072096348, states[0] = -11.945372, states[40]= 0.001933
Saving checkpoint... 
Iteration: 2084924174, states[0] = -94.884940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097611820, states[0] = -25.527793, states[40]= 0.000725
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.774428
 - CaMKt in component CaMK (millimolar): 0.006923
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.520925
 - nass in component intracellular_ions (millimolar): 6.520983
 - ki in component intracellular_ions (millimolar): 145.458719
 - kss in component intracellular_ions (millimolar): 145.458701
 - cansr in component intracellular_ions (millimolar): 1.304664
 - cajsr in component intracellular_ions (millimolar): 1.266183
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003665
 - hf in component INa (dimensionless): 0.877772
 - hs in component INa (dimensionless): 0.877767
 - j in component INa (dimensionless): 0.877736
 - hsp in component INa (dimensionless): 0.721642
 - jp in component INa (dimensionless): 0.877715
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.704557
 - hLp in component INaL (dimensionless): 0.442438
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.612610
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.685481
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.929624
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999864
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001579
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.344455
 - xs1 in component IKs (dimensionless): 0.252201
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997371
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:42:06 (21760): called boinc_finish(0)

</stderr_txt>
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