𝕏

Task 55411778

Name HuVeMOp_20240630093549983651_ORdGradInc_k_25-Pueyo_APDR-conf_734_0
Workunit 26312583
Created 30 Jun 2024, 7:36:28 UTC
Sent 30 Jun 2024, 9:16:17 UTC
Report deadline 3 Jul 2024, 18:52:17 UTC
Received 1 Jul 2024, 21:14:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227060
Run time 2 hours 54 min 56 sec
CPU time 2 hours 29 min 1 sec
Validate state Valid
Credit 62.23
Device peak FLOPS 4.67 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 1.73 MB
Peak swap size 4.02 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093549983651_ORdGradInc_k_25-Pueyo_APDR-conf_734.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093549983651_ORdGradInc_k_25-Pueyo_APDR-conf_734_0_r1157322671_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093549983651_ORdGradInc_k_25-Pueyo_APDR-conf_734_0_r1157322671_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 97.351617
     * GNaL_b in INaL: 0.007292
     * Gto_b in Ito: 0.082683
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029870
     * GKs_b in IKs: 0.002145
     * GK1_b in IK1: 0.155340
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 74.600985
     * GKb_b in IKb: 0.003709
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022785
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11712641, states[0] = -94.841697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23630192, states[0] = -42.983965, states[40]= 0.000093
Saving checkpoint... 
Iteration: 35250933, states[0] = -94.826943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47543568, states[0] = 15.511198, states[40]= 0.005048
Saving checkpoint... 
Iteration: 59949776, states[0] = -94.924819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71354958, states[0] = -94.885287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83721912, states[0] = -94.736425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96419093, states[0] = -94.901446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108738974, states[0] = -94.760599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121372519, states[0] = -94.880767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133128907, states[0] = -37.791009, states[40]= 0.000202
Saving checkpoint... 
Iteration: 146524945, states[0] = 21.477913, states[40]= 0.006890
Saving checkpoint... 
Iteration: 159256178, states[0] = -94.782493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171406419, states[0] = -94.890703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182829365, states[0] = -94.854105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195104766, states[0] = -16.643734, states[40]= 0.001269
Saving checkpoint... 
Iteration: 206859663, states[0] = -94.871348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218296957, states[0] = -94.828132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230492543, states[0] = -94.908878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242234468, states[0] = -94.747663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253747014, states[0] = -94.767951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265921923, states[0] = -94.894504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277746621, states[0] = -94.767299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290299717, states[0] = -94.830425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302812952, states[0] = -94.841548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314690644, states[0] = -94.624456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327467184, states[0] = -94.904618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338880071, states[0] = -94.880230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351442930, states[0] = -94.899675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362813832, states[0] = -94.842184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374444652, states[0] = -94.900046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386755849, states[0] = -94.780713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399313340, states[0] = -94.841773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412562290, states[0] = 9.066499, states[40]= 0.004850
Saving checkpoint... 
Iteration: 425015718, states[0] = 23.100234, states[40]= 0.015878
Saving checkpoint... 
Iteration: 436814006, states[0] = -94.842267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448153169, states[0] = -62.028195, states[40]= 0.000004
Saving checkpoint... 
Iteration: 460222962, states[0] = -94.726697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471905641, states[0] = -94.889453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483713600, states[0] = -94.708425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496026633, states[0] = 21.098581, states[40]= 0.006475
Saving checkpoint... 
Iteration: 507967542, states[0] = -94.904553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520393786, states[0] = -94.885378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532113917, states[0] = -24.532405, states[40]= 0.000812
Saving checkpoint... 
Iteration: 544429783, states[0] = -94.896364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556534250, states[0] = 19.003368, states[40]= 0.005477
Saving checkpoint... 
Iteration: 568583988, states[0] = -1.081667, states[40]= 0.004058
Saving checkpoint... 
Iteration: 579989470, states[0] = -94.908065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593000951, states[0] = 46.481723, states[40]= 0.026418
Saving checkpoint... 
Iteration: 604173130, states[0] = -89.653313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616173942, states[0] = -90.497444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628735376, states[0] = -94.748853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640974975, states[0] = -94.905754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655659100, states[0] = -69.076126, states[40]= 0.000001
Saving checkpoint... 
Iteration: 666722827, states[0] = -94.726300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679411061, states[0] = -94.891014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692393552, states[0] = -94.885177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703841920, states[0] = -94.861088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715696366, states[0] = -94.665980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728796610, states[0] = -94.827267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741189095, states[0] = -94.599643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754574353, states[0] = 3.890210, states[40]= 0.004605
Saving checkpoint... 
Iteration: 767012518, states[0] = 23.507854, states[40]= 0.029098
Saving checkpoint... 
Iteration: 779487245, states[0] = -94.907601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791031462, states[0] = 19.822332, states[40]= 0.005735
Saving checkpoint... 
Iteration: 803465478, states[0] = -94.903977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814381858, states[0] = -94.880629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826782104, states[0] = -94.812711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839092157, states[0] = -6.352948, states[40]= 0.003072
Saving checkpoint... 
Iteration: 851316992, states[0] = -94.844276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863688227, states[0] = -94.580825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875665651, states[0] = -78.480726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887885062, states[0] = -94.881852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901424836, states[0] = -94.894820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913164724, states[0] = -77.023737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925253157, states[0] = -94.776526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937908727, states[0] = -94.890116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950440787, states[0] = -94.898773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962291801, states[0] = -94.822538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974372560, states[0] = -94.876599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985543485, states[0] = 15.997568, states[40]= 0.005040
Saving checkpoint... 
Iteration: 997400876, states[0] = -94.887525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009550960, states[0] = 13.353164, states[40]= 0.004930
Saving checkpoint... 
Iteration: 1022057709, states[0] = 10.848157, states[40]= 0.004887
Saving checkpoint... 
Iteration: 1033689513, states[0] = -94.607031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045870357, states[0] = -94.875569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058430155, states[0] = -94.896110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070832402, states[0] = -94.854935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083228477, states[0] = -94.736447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096020841, states[0] = 22.326878, states[40]= 0.008728
Saving checkpoint... 
Iteration: 1108536635, states[0] = 18.264843, states[40]= 0.005315
Saving checkpoint... 
Iteration: 1119737532, states[0] = -94.752149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131258871, states[0] = -94.784370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144032969, states[0] = 19.386234, states[40]= 0.005585
Saving checkpoint... 
Iteration: 1156640868, states[0] = -49.092787, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1169253308, states[0] = -94.776576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181810816, states[0] = -94.839235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192867908, states[0] = -94.874354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204708817, states[0] = -94.698111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218312843, states[0] = -94.840823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230499138, states[0] = -94.908970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243158078, states[0] = -67.784316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1254633064, states[0] = -41.477417, states[40]= 0.000119
Saving checkpoint... 
Iteration: 1266365886, states[0] = -94.873364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277949782, states[0] = -94.900549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289607047, states[0] = -18.601118, states[40]= 0.001100
Saving checkpoint... 
Iteration: 1301468149, states[0] = -94.904123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313163172, states[0] = -74.673398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325604198, states[0] = -16.132790, states[40]= 0.001322
Saving checkpoint... 
Iteration: 1336957625, states[0] = -94.902118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347929139, states[0] = -94.895652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359757699, states[0] = -94.782613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371766257, states[0] = -94.793875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384020711, states[0] = 22.350157, states[40]= 0.008818
Saving checkpoint... 
Iteration: 1396004122, states[0] = 31.508061, states[40]= 0.160472
Saving checkpoint... 
Iteration: 1407686963, states[0] = -94.543955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419880472, states[0] = -94.879654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432280235, states[0] = -94.810271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444987728, states[0] = -94.907221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457924997, states[0] = -94.894485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470236311, states[0] = -94.749861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482086901, states[0] = -2.823944, states[40]= 0.003772
Saving checkpoint... 
Iteration: 1493940441, states[0] = -94.898324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506776157, states[0] = -94.963786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518162589, states[0] = -94.794421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530070780, states[0] = -1.678925, states[40]= 0.004479
Saving checkpoint... 
Iteration: 1541979767, states[0] = -95.166392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553795955, states[0] = -25.417486, states[40]= 0.000745
Saving checkpoint... 
Iteration: 1565789336, states[0] = -19.004076, states[40]= 0.001157
Saving checkpoint... 
Iteration: 1578022047, states[0] = 21.430268, states[40]= 0.009310
Saving checkpoint... 
Iteration: 1589413349, states[0] = 23.710153, states[40]= 0.026128
Saving checkpoint... 
Iteration: 1599951767, states[0] = 8.744659, states[40]= 0.005599
Saving checkpoint... 
Iteration: 1611501205, states[0] = -95.073019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624032197, states[0] = -65.925419, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1635470416, states[0] = -94.993106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647806652, states[0] = -95.085554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660214930, states[0] = 23.302035, states[40]= 0.019798
Saving checkpoint... 
Iteration: 1671790066, states[0] = -95.049939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684677274, states[0] = -95.017539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697874891, states[0] = -95.010513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710317539, states[0] = 22.654253, states[40]= 0.013732
Saving checkpoint... 
Iteration: 1722690792, states[0] = -20.864721, states[40]= 0.001009
Saving checkpoint... 
Iteration: 1735035493, states[0] = -70.589141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1746685538, states[0] = -15.586148, states[40]= 0.001559
Saving checkpoint... 
Iteration: 1759042167, states[0] = -81.422291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770774580, states[0] = -95.009574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783122663, states[0] = -95.115278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794654016, states[0] = 7.549611, states[40]= 0.005528
Saving checkpoint... 
Iteration: 1806052412, states[0] = 11.920217, states[40]= 0.004985
Saving checkpoint... 
Iteration: 1816920572, states[0] = -94.936166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827908043, states[0] = -94.921051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839689035, states[0] = -94.641946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851613547, states[0] = -24.994672, states[40]= 0.000790
Saving checkpoint... 
Iteration: 1862708163, states[0] = -94.707484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874602341, states[0] = -14.900170, states[40]= 0.001473
Saving checkpoint... 
Iteration: 1886338748, states[0] = -94.863802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897012632, states[0] = 23.466588, states[40]= 0.028371
Saving checkpoint... 
Iteration: 1909700700, states[0] = -94.681821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921741820, states[0] = -94.760464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933179134, states[0] = -93.607716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945854600, states[0] = -94.868154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957788107, states[0] = -94.818775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971104628, states[0] = -16.524942, states[40]= 0.001281
Saving checkpoint... 
Iteration: 1983029585, states[0] = 20.339043, states[40]= 0.005966
Saving checkpoint... 
Iteration: 1995043449, states[0] = 16.007378, states[40]= 0.005041
Saving checkpoint... 
Iteration: 2008229919, states[0] = -94.738483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020968655, states[0] = -94.903760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033702306, states[0] = -94.683080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045894185, states[0] = -94.884471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058248179, states[0] = -94.768390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070075572, states[0] = 3.313394, states[40]= 0.004560
Saving checkpoint... 
Iteration: 2082642226, states[0] = -50.469167, states[40]= 0.000029
Saving checkpoint... 
Iteration: 2094076992, states[0] = 2.625608, states[40]= 0.004501
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.784319
 - CaMKt in component CaMK (millimolar): 0.007293
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.489046
 - nass in component intracellular_ions (millimolar): 6.489107
 - ki in component intracellular_ions (millimolar): 145.485162
 - kss in component intracellular_ions (millimolar): 145.485143
 - cansr in component intracellular_ions (millimolar): 1.326109
 - cajsr in component intracellular_ions (millimolar): 1.286819
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003662
 - hf in component INa (dimensionless): 0.877946
 - hs in component INa (dimensionless): 0.877941
 - j in component INa (dimensionless): 0.877908
 - hsp in component INa (dimensionless): 0.721967
 - jp in component INa (dimensionless): 0.877885
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.703763
 - hLp in component INaL (dimensionless): 0.439787
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.608700
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.680849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.926481
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999853
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001665
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.348617
 - xs1 in component IKs (dimensionless): 0.259219
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997368
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:14:08 (615633): called boinc_finish(0)

</stderr_txt>
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