𝕏

Task 55411647

Name HuVeMOp_20240630093549983651_ORdGradInc_k_25-Pueyo_APDR-conf_431_1
Workunit 26312517
Created 30 Jun 2024, 7:36:23 UTC
Sent 30 Jun 2024, 9:13:32 UTC
Report deadline 3 Jul 2024, 18:49:32 UTC
Received 2 Jul 2024, 13:06:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234951
Run time 2 hours 31 min 42 sec
CPU time 2 hours 31 min 20 sec
Validate state Valid
Credit 60.59
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093549983651_ORdGradInc_k_25-Pueyo_APDR-conf_431.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093549983651_ORdGradInc_k_25-Pueyo_APDR-conf_431_1_r1150510332_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630093549983651_ORdGradInc_k_25-Pueyo_APDR-conf_431_1_r1150510332_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 108.889707
     * GNaL_b in INaL: 0.005803
     * Gto_b in Ito: 0.081799
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033055
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.176353
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 72.518232
     * GKb_b in IKb: 0.003811
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052736
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15740154, states[0] = -95.046681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30428806, states[0] = -95.113144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45336037, states[0] = -95.068789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59802419, states[0] = -95.041001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75559009, states[0] = 6.819468, states[40]= 0.004865
Saving checkpoint... 
Iteration: 90236018, states[0] = -94.970739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104806364, states[0] = -95.030473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119096608, states[0] = -19.592918, states[40]= 0.000982
Saving checkpoint... 
Iteration: 133746878, states[0] = -94.978424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148249315, states[0] = -94.980434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162868539, states[0] = -95.054894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178103286, states[0] = -26.037868, states[40]= 0.000622
Saving checkpoint... 
Iteration: 192685409, states[0] = -94.883737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207111120, states[0] = -33.814615, states[40]= 0.000283
Saving checkpoint... 
Iteration: 221852040, states[0] = -95.048338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236917571, states[0] = -95.067077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251506458, states[0] = 26.141055, states[40]= 0.114260
Saving checkpoint... 
Iteration: 265704100, states[0] = -94.917079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281290728, states[0] = -95.015739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296604850, states[0] = -27.554058, states[40]= 0.000551
Saving checkpoint... 
Iteration: 310964060, states[0] = -95.074762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325558229, states[0] = 7.411259, states[40]= 0.004884
Saving checkpoint... 
Iteration: 340160246, states[0] = -94.125793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354790428, states[0] = -95.015464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369150850, states[0] = -85.097586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384118021, states[0] = -40.866248, states[40]= 0.000107
Saving checkpoint... 
Iteration: 398583084, states[0] = -6.834126, states[40]= 0.003024
Saving checkpoint... 
Iteration: 412983389, states[0] = -95.077057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428173796, states[0] = -94.854242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443842228, states[0] = -95.044110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458403906, states[0] = -95.063847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473432814, states[0] = -95.069801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488028030, states[0] = 18.971748, states[40]= 0.006682
Saving checkpoint... 
Iteration: 503420637, states[0] = -95.067468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518116756, states[0] = -39.544277, states[40]= 0.000129
Saving checkpoint... 
Iteration: 532906395, states[0] = -95.064384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547348410, states[0] = -95.046596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561674478, states[0] = -94.856935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575820444, states[0] = -95.033733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590315373, states[0] = -95.030992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604873206, states[0] = -95.055377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620030051, states[0] = 18.340253, states[40]= 0.006323
Saving checkpoint... 
Iteration: 634195335, states[0] = -94.901584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648669270, states[0] = -94.819365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663439242, states[0] = -95.070813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677748638, states[0] = -94.978181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692924299, states[0] = -95.068085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706967467, states[0] = -95.074977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721280409, states[0] = -95.007758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736001669, states[0] = 48.157167, states[40]= 0.062092
Saving checkpoint... 
Iteration: 750725316, states[0] = -94.949326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764885765, states[0] = -95.059014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779214377, states[0] = -94.933311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793512835, states[0] = 22.607611, states[40]= 0.028952
Saving checkpoint... 
Iteration: 807704703, states[0] = -94.917745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822105130, states[0] = -27.830295, states[40]= 0.000538
Saving checkpoint... 
Iteration: 836492972, states[0] = -95.077835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851068141, states[0] = 2.721635, states[40]= 0.004577
Saving checkpoint... 
Iteration: 865144097, states[0] = -72.842442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 879741848, states[0] = -94.970374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893709133, states[0] = -94.924979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907799917, states[0] = -95.021574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922015480, states[0] = 22.063089, states[40]= 0.017881
Saving checkpoint... 
Iteration: 937357527, states[0] = -95.049862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952385644, states[0] = -95.058874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967596844, states[0] = -19.638194, states[40]= 0.000978
Saving checkpoint... 
Iteration: 982006156, states[0] = 26.603597, states[40]= 0.120383
Saving checkpoint... 
Iteration: 996754272, states[0] = -94.983984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011489995, states[0] = -95.077429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026440981, states[0] = -95.070899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040709554, states[0] = -94.925573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054886655, states[0] = -95.059097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069328323, states[0] = -95.037436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084350654, states[0] = -95.047178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098715609, states[0] = -94.935014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113462693, states[0] = -95.074114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128353021, states[0] = -95.048068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142981977, states[0] = -95.076485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157383569, states[0] = -95.058171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171502703, states[0] = 40.072847, states[40]= 0.110768
Saving checkpoint... 
Iteration: 1186316647, states[0] = -95.031353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200631122, states[0] = -55.483465, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1214997058, states[0] = -95.078027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229315526, states[0] = -95.030713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244453894, states[0] = -95.072797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258975315, states[0] = -95.075643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273165486, states[0] = -94.724054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287852327, states[0] = -95.047712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302349765, states[0] = -95.046706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316662454, states[0] = -94.500368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331167283, states[0] = -94.782900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345207122, states[0] = -94.921449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359444063, states[0] = -95.071215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373658371, states[0] = -93.520420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388893348, states[0] = -95.060705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405259619, states[0] = -94.989117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420647045, states[0] = -77.962085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435032317, states[0] = 17.594951, states[40]= 0.006014
Saving checkpoint... 
Iteration: 1449174810, states[0] = -94.857659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463716301, states[0] = -94.935856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478208366, states[0] = -94.923404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492174017, states[0] = -94.854565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506558504, states[0] = -95.263330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520802957, states[0] = -42.893604, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1534837276, states[0] = 13.742021, states[40]= 0.006387
Saving checkpoint... 
Iteration: 1549110898, states[0] = -95.244249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563477440, states[0] = -95.192404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579443405, states[0] = -95.291173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594121081, states[0] = -95.268296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608801896, states[0] = -95.242611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622991117, states[0] = -95.331281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637010840, states[0] = -95.256993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651015730, states[0] = -61.836003, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1665173776, states[0] = -95.193076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680328886, states[0] = 17.278762, states[40]= 0.007520
Saving checkpoint... 
Iteration: 1694520607, states[0] = -69.161414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1708831550, states[0] = 16.105899, states[40]= 0.007051
Saving checkpoint... 
Iteration: 1723066928, states[0] = -95.178438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738409841, states[0] = -95.256225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752605237, states[0] = 29.699327, states[40]= 0.119411
Saving checkpoint... 
Iteration: 1767260808, states[0] = -95.311493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1781320167, states[0] = -95.270091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797392776, states[0] = -33.287494, states[40]= 0.000303
Saving checkpoint... 
Iteration: 1812127814, states[0] = -55.449763, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1826303282, states[0] = -95.051199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839986268, states[0] = -95.095218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853643099, states[0] = -72.836545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1867576781, states[0] = -2.570490, states[40]= 0.003883
Saving checkpoint... 
Iteration: 1883623598, states[0] = -47.300150, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1897789104, states[0] = -95.016896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912509658, states[0] = 23.543739, states[40]= 0.057745
Saving checkpoint... 
Iteration: 1926592005, states[0] = -14.972685, states[40]= 0.001475
Saving checkpoint... 
Iteration: 1940741890, states[0] = -94.970693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955285473, states[0] = -95.011483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969326968, states[0] = -95.036599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983181248, states[0] = -94.874298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997401833, states[0] = -95.062599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011688424, states[0] = -94.888172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025947068, states[0] = -95.071338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041467899, states[0] = -95.074272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055718714, states[0] = -94.939107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072372096, states[0] = -95.054162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086263934, states[0] = -94.992810, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.953643
 - CaMKt in component CaMK (millimolar): 0.006670
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.546863
 - nass in component intracellular_ions (millimolar): 6.546921
 - ki in component intracellular_ions (millimolar): 145.435297
 - kss in component intracellular_ions (millimolar): 145.435277
 - cansr in component intracellular_ions (millimolar): 1.293892
 - cajsr in component intracellular_ions (millimolar): 1.256636
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003600
 - hf in component INa (dimensionless): 0.880897
 - hs in component INa (dimensionless): 0.880893
 - j in component INa (dimensionless): 0.880869
 - hsp in component INa (dimensionless): 0.727525
 - jp in component INa (dimensionless): 0.880853
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712815
 - hLp in component INaL (dimensionless): 0.458230
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.627113
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.703165
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937951
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999895
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001534
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327790
 - xs1 in component IKs (dimensionless): 0.234604
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997323
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:06:19 (366847): called boinc_finish(0)

</stderr_txt>
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