𝕏

Task 55410081

Name HuVeMOp_20240630085718245534_ORdGradInc_k_25-Pueyo_APDR-conf_463_0
Workunit 26311780
Created 30 Jun 2024, 6:58:29 UTC
Sent 30 Jun 2024, 9:01:43 UTC
Report deadline 3 Jul 2024, 18:37:43 UTC
Received 2 Jul 2024, 12:49:51 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234951
Run time 2 hours 31 min 22 sec
CPU time 2 hours 31 min 1 sec
Validate state Valid
Credit 59.73
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085718245534_ORdGradInc_k_25-Pueyo_APDR-conf_463.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085718245534_ORdGradInc_k_25-Pueyo_APDR-conf_463_0_r1328015003_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085718245534_ORdGradInc_k_25-Pueyo_APDR-conf_463_0_r1328015003_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.834153
     * GNaL_b in INaL: 0.004657
     * Gto_b in Ito: 0.084066
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033798
     * GKs_b in IKs: 0.001969
     * GK1_b in IK1: 0.155866
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 69.365071
     * GKb_b in IKb: 0.003869
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.047517
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14704061, states[0] = -94.749353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29019026, states[0] = 20.012138, states[40]= 0.010724
Saving checkpoint... 
Iteration: 44214632, states[0] = -94.718361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59098423, states[0] = -26.071919, states[40]= 0.000596
Saving checkpoint... 
Iteration: 74365658, states[0] = -94.837938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88516580, states[0] = 20.823714, states[40]= 0.014532
Saving checkpoint... 
Iteration: 103266767, states[0] = -94.767039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117896772, states[0] = -94.840636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133161114, states[0] = -94.029745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147630735, states[0] = -59.108756, states[40]= 0.000005
Saving checkpoint... 
Iteration: 162288654, states[0] = -94.783616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176306256, states[0] = -94.796703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190521088, states[0] = 19.855097, states[40]= 0.009019
Saving checkpoint... 
Iteration: 204768146, states[0] = -94.764109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219072120, states[0] = -1.564606, states[40]= 0.004040
Saving checkpoint... 
Iteration: 233793274, states[0] = -94.786628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247930693, states[0] = -94.846058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262101046, states[0] = -27.854240, states[40]= 0.000514
Saving checkpoint... 
Iteration: 276708730, states[0] = -94.680321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292632738, states[0] = -61.297545, states[40]= 0.000003
Saving checkpoint... 
Iteration: 307117825, states[0] = -45.006252, states[40]= 0.000053
Saving checkpoint... 
Iteration: 321871067, states[0] = -94.829277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336660778, states[0] = -93.949277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351992291, states[0] = -94.855596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366558115, states[0] = 5.904388, states[40]= 0.004783
Saving checkpoint... 
Iteration: 380921453, states[0] = -94.843910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394966924, states[0] = -94.852270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410281824, states[0] = -94.776820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424078583, states[0] = -6.167022, states[40]= 0.003172
Saving checkpoint... 
Iteration: 438937459, states[0] = -94.847242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453293418, states[0] = -94.786514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467863022, states[0] = -94.826111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482202129, states[0] = -94.667668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496889015, states[0] = -94.835215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512024454, states[0] = 18.963572, states[40]= 0.007400
Saving checkpoint... 
Iteration: 527754247, states[0] = -94.748386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542369423, states[0] = -94.828527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556804122, states[0] = -94.794461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570758954, states[0] = -94.753791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584904960, states[0] = -94.839732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599380394, states[0] = -94.832375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614348981, states[0] = -94.820057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629140493, states[0] = -70.890417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 643260240, states[0] = -94.755185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657651067, states[0] = -87.161885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672294627, states[0] = -94.787329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686591357, states[0] = -18.086558, states[40]= 0.001106
Saving checkpoint... 
Iteration: 700791578, states[0] = -94.784896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714970343, states[0] = -94.852568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729821585, states[0] = -94.805706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744761052, states[0] = -94.756021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759096116, states[0] = -22.886005, states[40]= 0.000757
Saving checkpoint... 
Iteration: 773100131, states[0] = -26.930434, states[40]= 0.000557
Saving checkpoint... 
Iteration: 787948125, states[0] = -94.849005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802295411, states[0] = -94.787859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816509683, states[0] = 22.530111, states[40]= 0.056266
Saving checkpoint... 
Iteration: 830903560, states[0] = -94.839208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844944400, states[0] = -94.848303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859071003, states[0] = -0.862753, states[40]= 0.004146
Saving checkpoint... 
Iteration: 873358575, states[0] = -94.824062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887693220, states[0] = -94.649569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902780554, states[0] = -94.775383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918223507, states[0] = -94.705447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932415820, states[0] = -94.842260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947777451, states[0] = -94.772515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962965290, states[0] = -94.851682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977364070, states[0] = -94.826214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991530324, states[0] = 17.139188, states[40]= 0.006120
Saving checkpoint... 
Iteration: 1005894067, states[0] = -94.836429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020479385, states[0] = -94.853611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034493934, states[0] = -94.855364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048603205, states[0] = -30.025982, states[40]= 0.000416
Saving checkpoint... 
Iteration: 1062888249, states[0] = -94.834633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077522685, states[0] = 19.448559, states[40]= 0.008111
Saving checkpoint... 
Iteration: 1092127463, states[0] = -55.406573, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1106703351, states[0] = -94.669647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121003184, states[0] = 35.291434, states[40]= 0.135944
Saving checkpoint... 
Iteration: 1135279245, states[0] = -94.774053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149842095, states[0] = -94.816494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165037737, states[0] = 14.459518, states[40]= 0.005412
Saving checkpoint... 
Iteration: 1179179989, states[0] = -94.619478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193742622, states[0] = -94.733377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208833054, states[0] = -94.811863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223595040, states[0] = -21.800749, states[40]= 0.000820
Saving checkpoint... 
Iteration: 1237918900, states[0] = -94.842801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252716157, states[0] = -94.692963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267190326, states[0] = -94.643299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281496870, states[0] = -94.855540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295608996, states[0] = -35.873176, states[40]= 0.000205
Saving checkpoint... 
Iteration: 1310206143, states[0] = -94.674838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325758007, states[0] = -94.752258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340005062, states[0] = 27.617924, states[40]= 0.142328
Saving checkpoint... 
Iteration: 1355312184, states[0] = -94.799461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369845797, states[0] = -94.818127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384057654, states[0] = 6.117797, states[40]= 0.004794
Saving checkpoint... 
Iteration: 1398503319, states[0] = 34.498864, states[40]= 0.139428
Saving checkpoint... 
Iteration: 1412500910, states[0] = 46.250135, states[40]= 0.019913
Saving checkpoint... 
Iteration: 1427590759, states[0] = -17.484414, states[40]= 0.001167
Saving checkpoint... 
Iteration: 1442551828, states[0] = 8.712846, states[40]= 0.004918
Saving checkpoint... 
Iteration: 1456695671, states[0] = -94.654238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470708085, states[0] = -94.678368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485096616, states[0] = -23.389526, states[40]= 0.000730
Saving checkpoint... 
Iteration: 1499621534, states[0] = -48.966697, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1513656754, states[0] = -94.900037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528228867, states[0] = 16.565916, states[40]= 0.007362
Saving checkpoint... 
Iteration: 1542793111, states[0] = -95.015452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557506803, states[0] = -95.047945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1571491081, states[0] = -35.004461, states[40]= 0.000233
Saving checkpoint... 
Iteration: 1585749389, states[0] = -95.112490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600166106, states[0] = -95.130322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614954320, states[0] = 2.494474, states[40]= 0.005111
Saving checkpoint... 
Iteration: 1631218449, states[0] = -69.393150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1645858086, states[0] = -0.139522, states[40]= 0.004751
Saving checkpoint... 
Iteration: 1660008561, states[0] = -56.382084, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1674590224, states[0] = -95.151582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689107106, states[0] = -54.592921, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1703577923, states[0] = -95.003711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1718816401, states[0] = -66.562775, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1733193030, states[0] = -37.657559, states[40]= 0.000163
Saving checkpoint... 
Iteration: 1748185906, states[0] = -29.398573, states[40]= 0.000445
Saving checkpoint... 
Iteration: 1763131268, states[0] = 15.138355, states[40]= 0.006921
Saving checkpoint... 
Iteration: 1777020404, states[0] = -72.415269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1791409946, states[0] = -58.137653, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1806078869, states[0] = -9.030795, states[40]= 0.002626
Saving checkpoint... 
Iteration: 1820592179, states[0] = -21.034969, states[40]= 0.000874
Saving checkpoint... 
Iteration: 1834513924, states[0] = 21.234016, states[40]= 0.022460
Saving checkpoint... 
Iteration: 1848444280, states[0] = -94.865564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862885692, states[0] = -94.844954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876967342, states[0] = -94.859033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890789470, states[0] = -94.787527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904794870, states[0] = -94.790091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921236570, states[0] = -94.726662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936505783, states[0] = 26.040300, states[40]= 0.129237
Saving checkpoint... 
Iteration: 1950528873, states[0] = 17.609858, states[40]= 0.006343
Saving checkpoint... 
Iteration: 1965164246, states[0] = -94.360868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979138562, states[0] = -68.353091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1993208531, states[0] = -94.679073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008261917, states[0] = -94.756306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023993381, states[0] = -94.854748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037911771, states[0] = -94.840614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052731697, states[0] = -94.717444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066733373, states[0] = -94.719895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080870020, states[0] = -94.827780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094838167, states[0] = -94.813934, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.731215
 - CaMKt in component CaMK (millimolar): 0.006621
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.659009
 - nass in component intracellular_ions (millimolar): 6.659067
 - ki in component intracellular_ions (millimolar): 145.322570
 - kss in component intracellular_ions (millimolar): 145.322551
 - cansr in component intracellular_ions (millimolar): 1.294640
 - cajsr in component intracellular_ions (millimolar): 1.257845
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003681
 - hf in component INa (dimensionless): 0.877008
 - hs in component INa (dimensionless): 0.877004
 - j in component INa (dimensionless): 0.876977
 - hsp in component INa (dimensionless): 0.720218
 - jp in component INa (dimensionless): 0.876958
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.707274
 - hLp in component INaL (dimensionless): 0.452584
 - a in component Ito (dimensionless): 0.000631
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.629170
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.705814
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.942741
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999909
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001536
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.316639
 - xs1 in component IKs (dimensionless): 0.224995
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997382
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:49:36 (366820): called boinc_finish(0)

</stderr_txt>
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