𝕏

Task 55409947

Name HuVeMOp_20240630085718245534_ORdGradInc_k_25-Pueyo_APDR-conf_345_0
Workunit 26311713
Created 30 Jun 2024, 6:58:24 UTC
Sent 30 Jun 2024, 8:56:35 UTC
Report deadline 3 Jul 2024, 18:32:35 UTC
Received 30 Jun 2024, 12:15:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 229534
Run time 2 hours 14 min 32 sec
CPU time 2 hours 13 min 12 sec
Validate state Valid
Credit 62.33
Device peak FLOPS 4.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.86 MB
Peak swap size 6.39 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085718245534_ORdGradInc_k_25-Pueyo_APDR-conf_345.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085718245534_ORdGradInc_k_25-Pueyo_APDR-conf_345_0_r806774658_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085718245534_ORdGradInc_k_25-Pueyo_APDR-conf_345_0_r806774658_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.596289
     * GNaL_b in INaL: 0.004938
     * Gto_b in Ito: 0.093809
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032826
     * GKs_b in IKs: 0.001866
     * GK1_b in IK1: 0.172674
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 66.532615
     * GKb_b in IKb: 0.003714
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027561
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17096733, states[0] = -21.311254, states[40]= 0.000860
Saving checkpoint... 
Iteration: 34349177, states[0] = -95.023215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51589186, states[0] = -12.664616, states[40]= 0.001835
Saving checkpoint... 
Iteration: 68535884, states[0] = 15.627695, states[40]= 0.005241
Saving checkpoint... 
Iteration: 85402379, states[0] = -95.024443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102133144, states[0] = -56.198476, states[40]= 0.000010
Saving checkpoint... 
Iteration: 119368985, states[0] = -95.010381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136657371, states[0] = -90.933417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153925461, states[0] = -95.026011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171146537, states[0] = -73.175961, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188401724, states[0] = -95.019560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205491275, states[0] = -95.036610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222736552, states[0] = -94.904552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239931423, states[0] = -95.026655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257024300, states[0] = 19.108007, states[40]= 0.006874
Saving checkpoint... 
Iteration: 274317761, states[0] = -94.983180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291567372, states[0] = 3.065234, states[40]= 0.004533
Saving checkpoint... 
Iteration: 308825636, states[0] = -94.987891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325624177, states[0] = -46.190757, states[40]= 0.000050
Saving checkpoint... 
Iteration: 342652322, states[0] = -83.209695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359940821, states[0] = -95.028443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377195791, states[0] = -94.833340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394463453, states[0] = -95.032427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411702458, states[0] = -94.846711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428943732, states[0] = -95.028956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446134788, states[0] = -57.809282, states[40]= 0.000007
Saving checkpoint... 
Iteration: 463326142, states[0] = -94.988064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480602288, states[0] = -24.451398, states[40]= 0.000714
Saving checkpoint... 
Iteration: 497877674, states[0] = -95.011492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515161690, states[0] = -93.669611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532033348, states[0] = 16.574818, states[40]= 0.005422
Saving checkpoint... 
Iteration: 549291937, states[0] = -94.964523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565781290, states[0] = -94.955406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582747911, states[0] = -94.919498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599981535, states[0] = -95.034925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617189267, states[0] = -94.819395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634432306, states[0] = -95.026503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651618278, states[0] = -40.094902, states[40]= 0.000125
Saving checkpoint... 
Iteration: 668903128, states[0] = -95.019361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686162394, states[0] = -93.889156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703389278, states[0] = -95.015223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720648974, states[0] = -77.168169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737912561, states[0] = -95.021825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754783798, states[0] = -94.957502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771971954, states[0] = -95.033453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788888164, states[0] = -95.014806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805382470, states[0] = -95.012923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822637253, states[0] = -60.669012, states[40]= 0.000005
Saving checkpoint... 
Iteration: 839811876, states[0] = -94.978953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856988113, states[0] = -95.035596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874228150, states[0] = -94.891477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891399399, states[0] = -95.018144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908630913, states[0] = -53.467574, states[40]= 0.000016
Saving checkpoint... 
Iteration: 925852493, states[0] = -95.001152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943102762, states[0] = -24.908597, states[40]= 0.000693
Saving checkpoint... 
Iteration: 960327618, states[0] = -94.988547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977581563, states[0] = -5.511613, states[40]= 0.003281
Saving checkpoint... 
Iteration: 994684305, states[0] = -94.807937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011839175, states[0] = -94.994730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029082122, states[0] = -5.935129, states[40]= 0.003193
Saving checkpoint... 
Iteration: 1045886798, states[0] = -95.014179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063123729, states[0] = -45.717069, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1080414505, states[0] = -95.022068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097633221, states[0] = -56.035144, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1114883178, states[0] = -95.012936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132154366, states[0] = -86.765617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149415147, states[0] = -95.022178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165896936, states[0] = -95.017226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183141187, states[0] = -65.516737, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1200356692, states[0] = -95.002795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217630053, states[0] = -52.521228, states[40]= 0.000018


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085718245534_ORdGradInc_k_25-Pueyo_APDR-conf_345.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085718245534_ORdGradInc_k_25-Pueyo_APDR-conf_345_0_r806774658_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085718245534_ORdGradInc_k_25-Pueyo_APDR-conf_345_0_r806774658_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.596289
     * GNaL_b in INaL: 0.004938
     * Gto_b in Ito: 0.093809
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032826
     * GKs_b in IKs: 0.001866
     * GK1_b in IK1: 0.172674
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 66.532615
     * GKb_b in IKb: 0.003714
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027561
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1217630053
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -52.521228 (After loading)
 - states[40]: 0.000018 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1234789800, states[0] = -94.962273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252026998, states[0] = 18.434213, states[40]= 0.006215
Saving checkpoint... 
Iteration: 1269018831, states[0] = 20.218508, states[40]= 0.010226
Saving checkpoint... 
Iteration: 1286301348, states[0] = -94.971260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303561757, states[0] = 5.706376, states[40]= 0.004691
Saving checkpoint... 
Iteration: 1320791914, states[0] = -94.963942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337983191, states[0] = -95.034610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355230923, states[0] = -94.895369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372473774, states[0] = -95.033282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389726398, states[0] = -94.888357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406955996, states[0] = -95.030461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423857948, states[0] = -95.003169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441098833, states[0] = -21.115532, states[40]= 0.000886
Saving checkpoint... 
Iteration: 1457488702, states[0] = -95.035234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472304045, states[0] = -94.973086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489414181, states[0] = -95.021689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506428042, states[0] = -74.284310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1523405324, states[0] = 27.366593, states[40]= 0.131714
Saving checkpoint... 
Iteration: 1540552989, states[0] = 5.081536, states[40]= 0.005306
Saving checkpoint... 
Iteration: 1557693406, states[0] = -33.312678, states[40]= 0.000312
Saving checkpoint... 
Iteration: 1574783435, states[0] = -22.435553, states[40]= 0.000853
Saving checkpoint... 
Iteration: 1591994343, states[0] = -95.175028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609137987, states[0] = -95.243449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626295365, states[0] = -95.294967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643074142, states[0] = -95.280279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660222907, states[0] = 18.797091, states[40]= 0.008571
Saving checkpoint... 
Iteration: 1677014141, states[0] = 21.249580, states[40]= 0.022518
Saving checkpoint... 
Iteration: 1692752807, states[0] = -95.070596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709869420, states[0] = -95.123545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726495361, states[0] = -95.296059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743631421, states[0] = 15.535864, states[40]= 0.006570
Saving checkpoint... 
Iteration: 1760763190, states[0] = -2.159291, states[40]= 0.004401
Saving checkpoint... 
Iteration: 1777686342, states[0] = -95.162534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794437301, states[0] = -93.440427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811522066, states[0] = 19.147377, states[40]= 0.007429
Saving checkpoint... 
Iteration: 1828439268, states[0] = -95.055269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845626484, states[0] = -49.985050, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1862733585, states[0] = -94.909597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879893938, states[0] = -95.022046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897053350, states[0] = 9.186352, states[40]= 0.004802
Saving checkpoint... 
Iteration: 1913933328, states[0] = -95.028052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931003567, states[0] = 32.169497, states[40]= 0.164439
Saving checkpoint... 
Iteration: 1948180943, states[0] = -94.799475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964198545, states[0] = -94.838279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981226608, states[0] = -94.888527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998403012, states[0] = -95.018496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015542969, states[0] = 13.245688, states[40]= 0.004956
Saving checkpoint... 
Iteration: 2032708374, states[0] = -94.856852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049773042, states[0] = -94.946540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066900111, states[0] = -95.017454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083888036, states[0] = -95.013773, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.911933
 - CaMKt in component CaMK (millimolar): 0.007145
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.721584
 - nass in component intracellular_ions (millimolar): 6.721645
 - ki in component intracellular_ions (millimolar): 145.252096
 - kss in component intracellular_ions (millimolar): 145.252076
 - cansr in component intracellular_ions (millimolar): 1.325510
 - cajsr in component intracellular_ions (millimolar): 1.287675
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003615
 - hf in component INa (dimensionless): 0.880176
 - hs in component INa (dimensionless): 0.880171
 - j in component INa (dimensionless): 0.880143
 - hsp in component INa (dimensionless): 0.726160
 - jp in component INa (dimensionless): 0.880124
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711101
 - hLp in component INaL (dimensionless): 0.455118
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.625190
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.701286
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939802
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999899
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001649
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.317529
 - xs1 in component IKs (dimensionless): 0.234129
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997334
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:46:37 (4496): called boinc_finish(0)

</stderr_txt>
]]>