Task 55408269

Name	HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_693_0
Workunit	26310875
Created	30 Jun 2024, 6:57:17 UTC
Sent	30 Jun 2024, 8:42:37 UTC
Report deadline	3 Jul 2024, 18:18:37 UTC
Received	2 Jul 2024, 17:11:33 UTC
Server state	Over
Outcome	Success
Client state	Done
Exit status	0 (0x00000000)
Computer ID	190678
Run time	2 hours 22 min 11 sec
CPU time	2 hours 21 min 3 sec
Validate state	Valid
Credit	61.75
Device peak FLOPS	3.57 GFLOPS
Application version	Human ventricular cell models optimization v0.02 windows_x86_64
Peak working set size	5.20 MB
Peak swap size	1.41 MB
Peak disk usage	0.27 MB
Stderr output

<core_client_version>7.6.33</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_693.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_693_0_r1542826552_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_693_0_r1542826552_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.742775
     * GNaL_b in INaL: 0.004832
     * Gto_b in Ito: 0.098183
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.002058
     * GK1_b in IK1: 0.150988
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 73.382013
     * GKb_b in IKb: 0.003905
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.047040
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14866932, states[0] = -94.969189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29799147, states[0] = -94.889134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44750117, states[0] = -94.816087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59712372, states[0] = -94.742253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74661396, states[0] = -93.879792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89564831, states[0] = 2.658788, states[40]= 0.004466
Saving checkpoint... 
Iteration: 104466931, states[0] = -94.900035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119427742, states[0] = -94.890606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134378407, states[0] = -94.875103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149302051, states[0] = -94.833317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164216816, states[0] = -94.728311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179143747, states[0] = -73.422202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194063206, states[0] = 3.637127, states[40]= 0.004535
Saving checkpoint... 
Iteration: 209014290, states[0] = 20.113605, states[40]= 0.020756
Saving checkpoint... 
Iteration: 223846979, states[0] = -94.859661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238797292, states[0] = -94.828160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253745712, states[0] = -94.773368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268687127, states[0] = -94.665694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283564079, states[0] = 3.215422, states[40]= 0.004505
Saving checkpoint... 
Iteration: 298379347, states[0] = -94.873067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313335756, states[0] = -94.853650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328142524, states[0] = -71.676894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 343090095, states[0] = -16.020057, states[40]= 0.001321
Saving checkpoint... 
Iteration: 357930100, states[0] = -94.887389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372862430, states[0] = -94.866430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387815509, states[0] = -94.841333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402780702, states[0] = -94.813414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417728640, states[0] = -94.747622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432661596, states[0] = -93.719251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447580265, states[0] = -6.970776, states[40]= 0.002959
Saving checkpoint... 
Iteration: 462506503, states[0] = 23.101714, states[40]= 0.121533
Saving checkpoint... 
Iteration: 477450215, states[0] = -94.891332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492353849, states[0] = -94.862577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507316806, states[0] = -94.842111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522266530, states[0] = -94.798782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537228046, states[0] = -94.746567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552186739, states[0] = -94.664519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567122170, states[0] = -48.410731, states[40]= 0.000032
Saving checkpoint... 
Iteration: 581968223, states[0] = -94.894260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596931949, states[0] = -94.887626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611846814, states[0] = -94.859162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626798948, states[0] = -94.829116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641764668, states[0] = -94.796624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656721745, states[0] = -94.735823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671673400, states[0] = -94.604219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686305157, states[0] = -94.833831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701240472, states[0] = -94.765616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716102308, states[0] = -28.161854, states[40]= 0.000504
Saving checkpoint... 
Iteration: 730899555, states[0] = -94.879323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745797925, states[0] = -94.828221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760549687, states[0] = 9.570305, states[40]= 0.004790
Saving checkpoint... 
Iteration: 775068912, states[0] = 0.682493, states[40]= 0.004271
Saving checkpoint... 
Iteration: 789998400, states[0] = -94.898099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804871602, states[0] = -94.869827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819813387, states[0] = -94.839600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834774776, states[0] = -94.807291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849738683, states[0] = -94.762902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864672864, states[0] = -94.597743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879595424, states[0] = -21.317765, states[40]= 0.000846
Saving checkpoint... 
Iteration: 894514799, states[0] = 20.044728, states[40]= 0.018861
Saving checkpoint... 
Iteration: 909394295, states[0] = -94.877611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924339297, states[0] = -94.855122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939271498, states[0] = -94.803840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954218606, states[0] = -94.730059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968816933, states[0] = -94.841877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983388026, states[0] = -94.875558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998265395, states[0] = -94.797193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013203737, states[0] = -94.701460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028115568, states[0] = -41.480580, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1043058673, states[0] = 5.760514, states[40]= 0.004652
Saving checkpoint... 
Iteration: 1057984764, states[0] = -94.896262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072937344, states[0] = -94.888436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087908025, states[0] = -94.881476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102853285, states[0] = -94.861899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117761765, states[0] = -94.792978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132717288, states[0] = -94.727553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147680128, states[0] = -94.645419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162559426, states[0] = 5.420280, states[40]= 0.004636
Saving checkpoint... 
Iteration: 1177327514, states[0] = -94.848352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192283519, states[0] = -94.815516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207186453, states[0] = -94.663366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221925863, states[0] = -94.885841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236843822, states[0] = -94.857244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251698623, states[0] = -94.690647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266308748, states[0] = -94.836049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280842480, states[0] = -94.856531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295672540, states[0] = -94.593198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310610240, states[0] = -36.068771, states[40]= 0.000203
Saving checkpoint... 
Iteration: 1325520274, states[0] = 19.149698, states[40]= 0.009056
Saving checkpoint... 
Iteration: 1340448726, states[0] = -94.890467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355385356, states[0] = -94.874413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370357200, states[0] = -94.863483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385295778, states[0] = -94.826047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400232680, states[0] = -94.753399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415180008, states[0] = -94.644805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430146041, states[0] = -76.739815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445101883, states[0] = -27.739054, states[40]= 0.000523
Saving checkpoint... 
Iteration: 1459975931, states[0] = -94.894790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474909532, states[0] = -94.881617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489848187, states[0] = -94.859227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504652200, states[0] = -94.882119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1519530871, states[0] = 15.336272, states[40]= 0.006698
Saving checkpoint... 
Iteration: 1534434958, states[0] = -95.127068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549313365, states[0] = -61.163191, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1564196605, states[0] = -95.203226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579087747, states[0] = -95.069351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593975020, states[0] = -16.495575, states[40]= 0.001416
Saving checkpoint... 
Iteration: 1608866358, states[0] = -95.188179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623630558, states[0] = 14.996020, states[40]= 0.006699
Saving checkpoint... 
Iteration: 1638481500, states[0] = -95.061104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653314858, states[0] = 20.319302, states[40]= 0.020349
Saving checkpoint... 
Iteration: 1668183592, states[0] = -95.066480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683032553, states[0] = 14.100170, states[40]= 0.006442
Saving checkpoint... 
Iteration: 1697891599, states[0] = -95.084167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712650944, states[0] = -95.175162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727510829, states[0] = -58.983946, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1742372011, states[0] = -95.195474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757161897, states[0] = -3.166988, states[40]= 0.004158
Saving checkpoint... 
Iteration: 1771961438, states[0] = -95.009575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786725600, states[0] = -95.143547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801564865, states[0] = 0.923101, states[40]= 0.004421
Saving checkpoint... 
Iteration: 1816455044, states[0] = -94.942543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831347835, states[0] = -94.892111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846238509, states[0] = -94.783553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861138074, states[0] = -66.924829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1876036217, states[0] = 14.561377, states[40]= 0.005227
Saving checkpoint... 
Iteration: 1890924608, states[0] = -94.890447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905849887, states[0] = -94.863146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920655987, states[0] = -90.905134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935496500, states[0] = -94.898435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950333959, states[0] = -94.852360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965223757, states[0] = -94.738917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980127877, states[0] = -54.561675, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1994899351, states[0] = -94.878567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009796958, states[0] = -94.826663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024690981, states[0] = -94.673438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039605576, states[0] = -31.413387, states[40]= 0.000362
Saving checkpoint... 
Iteration: 2054506027, states[0] = 23.792756, states[40]= 0.133233
Saving checkpoint... 
Iteration: 2069348586, states[0] = -94.858986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084234579, states[0] = -94.755829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099129609, states[0] = -56.419859, states[40]= 0.000008
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.773206
 - CaMKt in component CaMK (millimolar): 0.006871
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.548181
 - nass in component intracellular_ions (millimolar): 6.548240
 - ki in component intracellular_ions (millimolar): 145.429787
 - kss in component intracellular_ions (millimolar): 145.429767
 - cansr in component intracellular_ions (millimolar): 1.307608
 - cajsr in component intracellular_ions (millimolar): 1.270358
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003666
 - hf in component INa (dimensionless): 0.877751
 - hs in component INa (dimensionless): 0.877746
 - j in component INa (dimensionless): 0.877718
 - hsp in component INa (dimensionless): 0.721605
 - jp in component INa (dimensionless): 0.877698
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.707968
 - hLp in component INaL (dimensionless): 0.452512
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.628090
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.704776
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.943926
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999910
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001577
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.314293
 - xs1 in component IKs (dimensionless): 0.225781
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997371
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:32:50 (9256): called boinc_finish(0)

</stderr_txt>
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