𝕏

Task 55408078

Name HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_285_1
Workunit 26310779
Created 30 Jun 2024, 6:57:07 UTC
Sent 30 Jun 2024, 8:41:15 UTC
Report deadline 3 Jul 2024, 18:17:15 UTC
Received 3 Jul 2024, 16:26:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227484
Run time 2 hours 47 min 50 sec
CPU time 2 hours 30 min 19 sec
Validate state Valid
Credit 58.02
Device peak FLOPS 4.67 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.41 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_285.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_285_1_r26065312_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_285_1_r26065312_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.720797
     * GNaL_b in INaL: 0.007422
     * Gto_b in Ito: 0.082857
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029755
     * GKs_b in IKs: 0.001788
     * GK1_b in IK1: 0.149537
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 66.714805
     * GKb_b in IKb: 0.003698
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021323
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13137411, states[0] = -47.921420, states[40]= 0.000042
Saving checkpoint... 
Iteration: 26413076, states[0] = -94.955629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39467773, states[0] = -94.953787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52454400, states[0] = -94.941580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65825225, states[0] = -94.880963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78404971, states[0] = -94.917562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90711379, states[0] = -94.720448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103043927, states[0] = 16.100658, states[40]= 0.005012
Saving checkpoint... 
Iteration: 116091175, states[0] = -4.765734, states[40]= 0.003389
Saving checkpoint... 
Iteration: 129004053, states[0] = 31.841653, states[40]= 0.161294
Saving checkpoint... 
Iteration: 141949861, states[0] = -94.922332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155392743, states[0] = -94.904892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167644845, states[0] = -51.400464, states[40]= 0.000026
Saving checkpoint... 
Iteration: 180194390, states[0] = -94.650224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193032868, states[0] = 19.653720, states[40]= 0.005574
Saving checkpoint... 
Iteration: 206577874, states[0] = 2.832330, states[40]= 0.004498
Saving checkpoint... 
Iteration: 219070632, states[0] = 6.122296, states[40]= 0.004721
Saving checkpoint... 
Iteration: 231664812, states[0] = -74.230346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244699413, states[0] = -94.681875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257672102, states[0] = -85.403426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270289262, states[0] = -94.835849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282421544, states[0] = -94.913504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295290465, states[0] = -94.837067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308092387, states[0] = -5.481136, states[40]= 0.003240
Saving checkpoint... 
Iteration: 320361701, states[0] = -94.889957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332772249, states[0] = -94.816296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346692514, states[0] = -94.625205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361099691, states[0] = -11.006406, states[40]= 0.002093
Saving checkpoint... 
Iteration: 375299206, states[0] = -94.845669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389861488, states[0] = -94.889792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403917699, states[0] = -94.912250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418612604, states[0] = -21.975239, states[40]= 0.000929
Saving checkpoint... 
Iteration: 432832119, states[0] = -94.872264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447391825, states[0] = -94.903336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461574435, states[0] = 4.447018, states[40]= 0.004623
Saving checkpoint... 
Iteration: 475558460, states[0] = 10.985598, states[40]= 0.004869
Saving checkpoint... 
Iteration: 489657192, states[0] = -64.531515, states[40]= 0.000003
Saving checkpoint... 
Iteration: 504036254, states[0] = 18.648065, states[40]= 0.005318
Saving checkpoint... 
Iteration: 518384388, states[0] = -94.900309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532518963, states[0] = 22.805499, states[40]= 0.010321
Saving checkpoint... 
Iteration: 547380304, states[0] = -94.898563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561912706, states[0] = -94.910590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575839839, states[0] = -94.877259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590186034, states[0] = -94.352897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604774937, states[0] = -94.819409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617434626, states[0] = -94.916855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631887130, states[0] = -94.901355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643799252, states[0] = -94.845528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656541331, states[0] = 17.027089, states[40]= 0.005083
Saving checkpoint... 
Iteration: 668917715, states[0] = -94.912073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681440760, states[0] = -94.918356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695307419, states[0] = -94.852933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708261610, states[0] = -94.802038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720618894, states[0] = -27.359249, states[40]= 0.000692
Saving checkpoint... 
Iteration: 733157246, states[0] = -64.593327, states[40]= 0.000003
Saving checkpoint... 
Iteration: 745607087, states[0] = -17.243632, states[40]= 0.001212
Saving checkpoint... 
Iteration: 758658771, states[0] = -66.376545, states[40]= 0.000002
Saving checkpoint... 
Iteration: 773301079, states[0] = -94.847157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786594746, states[0] = -7.163122, states[40]= 0.002884
Saving checkpoint... 
Iteration: 799575475, states[0] = 3.970475, states[40]= 0.004589
Saving checkpoint... 
Iteration: 812332366, states[0] = -94.872174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824682436, states[0] = -93.813040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837939814, states[0] = -94.918017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850204051, states[0] = -94.696280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862725302, states[0] = -94.741781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875241463, states[0] = -94.771033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887870122, states[0] = -94.893724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900850257, states[0] = -94.883330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913481508, states[0] = -94.926488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926095048, states[0] = -7.386003, states[40]= 0.002837
Saving checkpoint... 
Iteration: 938159715, states[0] = -67.512493, states[40]= 0.000002
Saving checkpoint... 
Iteration: 950790028, states[0] = -94.836147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963119661, states[0] = -28.018623, states[40]= 0.000657
Saving checkpoint... 
Iteration: 975520917, states[0] = 22.486111, states[40]= 0.008654
Saving checkpoint... 
Iteration: 988094833, states[0] = -7.227087, states[40]= 0.002871
Saving checkpoint... 
Iteration: 1000750388, states[0] = -94.785377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013988626, states[0] = -94.927568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026608321, states[0] = -18.303245, states[40]= 0.001125
Saving checkpoint... 
Iteration: 1039294262, states[0] = -94.840402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051782618, states[0] = -94.828066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064664716, states[0] = -74.080629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077410737, states[0] = -94.909607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090139534, states[0] = -46.020341, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1102400860, states[0] = -94.906239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114555364, states[0] = 12.131886, states[40]= 0.004886
Saving checkpoint... 
Iteration: 1127547610, states[0] = 14.897863, states[40]= 0.004946
Saving checkpoint... 
Iteration: 1140398294, states[0] = -94.905291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152711700, states[0] = -94.713901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165140133, states[0] = -46.611056, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1177965939, states[0] = -94.923509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191183555, states[0] = -94.038511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203702136, states[0] = -94.690623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216002370, states[0] = 41.447922, states[40]= 0.118954
Saving checkpoint... 
Iteration: 1228590161, states[0] = -3.989285, states[40]= 0.003539
Saving checkpoint... 
Iteration: 1240814789, states[0] = -94.858773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253770237, states[0] = -94.813127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266668428, states[0] = -79.661483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279054015, states[0] = 12.623056, states[40]= 0.004893
Saving checkpoint... 
Iteration: 1290938797, states[0] = -94.917457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303525699, states[0] = 21.520316, states[40]= 0.006669
Saving checkpoint... 
Iteration: 1316817585, states[0] = -94.860962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329649952, states[0] = -56.637908, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1343242563, states[0] = -94.772557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356653288, states[0] = -60.189145, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1369738338, states[0] = -94.765351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383488141, states[0] = -94.927241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397425432, states[0] = -94.913836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410745970, states[0] = -94.778106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423925477, states[0] = -94.913831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436806804, states[0] = -94.851887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450409005, states[0] = -94.908788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464288820, states[0] = -94.834531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477236698, states[0] = -94.762412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492154386, states[0] = -61.384746, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1506555020, states[0] = -95.130596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521085614, states[0] = -12.750781, states[40]= 0.002016
Saving checkpoint... 
Iteration: 1534070098, states[0] = -94.967059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546630735, states[0] = -61.114269, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1559814671, states[0] = -43.154168, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1572162508, states[0] = -94.833823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584651680, states[0] = 9.219762, states[40]= 0.005618
Saving checkpoint... 
Iteration: 1597431563, states[0] = -95.151623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609539414, states[0] = 14.911934, states[40]= 0.006075
Saving checkpoint... 
Iteration: 1622589200, states[0] = -95.067964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635229387, states[0] = -95.150852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647243348, states[0] = -95.172401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659190327, states[0] = -95.071971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671674257, states[0] = -4.330473, states[40]= 0.003970
Saving checkpoint... 
Iteration: 1684032721, states[0] = -64.907227, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1696269101, states[0] = -0.636259, states[40]= 0.004692
Saving checkpoint... 
Iteration: 1708489735, states[0] = -95.224042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720149701, states[0] = -95.181676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732737125, states[0] = -95.164050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1745912478, states[0] = -95.121497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758286170, states[0] = -95.221014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770743401, states[0] = -80.854127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783692608, states[0] = -95.077990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796131543, states[0] = 18.193198, states[40]= 0.006725
Saving checkpoint... 
Iteration: 1809913756, states[0] = -94.964851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822543164, states[0] = 15.883517, states[40]= 0.005040
Saving checkpoint... 
Iteration: 1835270215, states[0] = -94.841378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848176950, states[0] = -92.205268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860394645, states[0] = -94.917236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873077715, states[0] = 2.689845, states[40]= 0.004495
Saving checkpoint... 
Iteration: 1885345556, states[0] = -94.886584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898365435, states[0] = -94.895327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910888688, states[0] = -94.904271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923555424, states[0] = 12.074839, states[40]= 0.004886
Saving checkpoint... 
Iteration: 1936368879, states[0] = -94.893904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948823094, states[0] = -94.865793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960947309, states[0] = -94.919741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973505523, states[0] = 27.730519, states[40]= 0.139945
Saving checkpoint... 
Iteration: 1985584311, states[0] = -0.493090, states[40]= 0.004123
Saving checkpoint... 
Iteration: 1997803982, states[0] = -94.849189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010938733, states[0] = -94.917068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023329488, states[0] = -94.869417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035691983, states[0] = -94.615034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047400088, states[0] = -94.905319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059834811, states[0] = -94.872953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072447169, states[0] = -94.918898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085423799, states[0] = -94.912859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098730321, states[0] = -94.750398, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.804335
 - CaMKt in component CaMK (millimolar): 0.007350
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.671258
 - nass in component intracellular_ions (millimolar): 6.671319
 - ki in component intracellular_ions (millimolar): 145.302796
 - kss in component intracellular_ions (millimolar): 145.302776
 - cansr in component intracellular_ions (millimolar): 1.326724
 - cajsr in component intracellular_ions (millimolar): 1.287230
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003654
 - hf in component INa (dimensionless): 0.878298
 - hs in component INa (dimensionless): 0.878293
 - j in component INa (dimensionless): 0.878257
 - hsp in component INa (dimensionless): 0.722624
 - jp in component INa (dimensionless): 0.878234
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.703676
 - hLp in component INaL (dimensionless): 0.438678
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.606753
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.678480
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.924814
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999846
 - jca in component ICaL (dimensionless): 0.999971
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001658
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.351845
 - xs1 in component IKs (dimensionless): 0.262773
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997363
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:26:37 (34341): called boinc_finish(0)

</stderr_txt>
]]>


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