𝕏

Task 55408009

Name HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_76_0
Workunit 26310745
Created 30 Jun 2024, 6:57:02 UTC
Sent 30 Jun 2024, 8:41:04 UTC
Report deadline 3 Jul 2024, 18:17:04 UTC
Received 2 Jul 2024, 3:33:20 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220412
Run time 1 hours 53 min 26 sec
CPU time 1 hours 48 min 54 sec
Validate state Valid
Credit 58.16
Device peak FLOPS 3.50 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 9.76 MB
Peak swap size 5.17 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_76.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_76_0_r628217866_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_76_0_r628217866_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.549654
     * GNaL_b in INaL: 0.006926
     * Gto_b in Ito: 0.084512
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030829
     * GKs_b in IKs: 0.001874
     * GK1_b in IK1: 0.174811
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 65.843664
     * GKb_b in IKb: 0.003845
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022976
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14814445, states[0] = -95.007614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34632737, states[0] = -46.147146, states[40]= 0.000058
Saving checkpoint... 
Iteration: 54188533, states[0] = -94.805240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73585228, states[0] = -3.728427, states[40]= 0.003644
Saving checkpoint... 
Iteration: 92772470, states[0] = -94.933055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107367327, states[0] = -94.995347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126676704, states[0] = -94.566057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145942373, states[0] = -95.015817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160713431, states[0] = -94.846909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179893655, states[0] = -95.002867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199335273, states[0] = -94.977949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218540709, states[0] = 16.066310, states[40]= 0.005110
Saving checkpoint... 
Iteration: 237516802, states[0] = 22.278524, states[40]= 0.013237
Saving checkpoint... 
Iteration: 256172044, states[0] = -93.761131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275070144, states[0] = 4.619721, states[40]= 0.004684
Saving checkpoint... 
Iteration: 293593864, states[0] = -9.815676, states[40]= 0.002362
Saving checkpoint... 
Iteration: 312236524, states[0] = -94.884577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331097686, states[0] = -13.022116, states[40]= 0.001764
Saving checkpoint... 
Iteration: 350075216, states[0] = 2.194724, states[40]= 0.004493
Saving checkpoint... 
Iteration: 367733877, states[0] = -94.880545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384793993, states[0] = -94.949462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402715953, states[0] = -94.850812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421509647, states[0] = 23.485315, states[40]= 0.056532
Saving checkpoint... 
Iteration: 440490983, states[0] = -95.022813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459368903, states[0] = -94.993528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478862889, states[0] = -94.991029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498158581, states[0] = -76.076482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517141051, states[0] = -53.380472, states[40]= 0.000018
Saving checkpoint... 
Iteration: 536102649, states[0] = -17.360838, states[40]= 0.001206
Saving checkpoint... 
Iteration: 552669745, states[0] = -92.699409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571724868, states[0] = -94.866057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590535154, states[0] = 17.896958, states[40]= 0.005377
Saving checkpoint... 
Iteration: 609586311, states[0] = -4.197858, states[40]= 0.003547
Saving checkpoint... 
Iteration: 628451140, states[0] = -95.016458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647516027, states[0] = 22.388899, states[40]= 0.014873
Saving checkpoint... 
Iteration: 666387397, states[0] = -95.000195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685229787, states[0] = -94.873952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704259496, states[0] = -94.914836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723113383, states[0] = -26.814435, states[40]= 0.000692
Saving checkpoint... 
Iteration: 737518456, states[0] = 22.026453, states[40]= 0.010716
Saving checkpoint... 
Iteration: 756034041, states[0] = 18.244441, states[40]= 0.005456
Saving checkpoint... 
Iteration: 774576343, states[0] = 1.622695, states[40]= 0.004435
Saving checkpoint... 
Iteration: 792973465, states[0] = -95.020106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811339484, states[0] = -94.979638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829941812, states[0] = -95.014491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848325664, states[0] = -94.971745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866747423, states[0] = -94.899538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885097136, states[0] = -12.549913, states[40]= 0.001843
Saving checkpoint... 
Iteration: 903545768, states[0] = 14.297114, states[40]= 0.004987
Saving checkpoint... 
Iteration: 921862052, states[0] = -94.990350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940276774, states[0] = -94.933393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958451228, states[0] = -95.016235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976698431, states[0] = -94.816931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993464081, states[0] = -95.018472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013138778, states[0] = -50.936432, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1031507809, states[0] = 24.356879, states[40]= 0.088344
Saving checkpoint... 
Iteration: 1049988392, states[0] = -95.022034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063409609, states[0] = -95.006679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080608225, states[0] = -22.275656, states[40]= 0.000895


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_76.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_76_0_r628217866_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_76_0_r628217866_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.549654
     * GNaL_b in INaL: 0.006926
     * Gto_b in Ito: 0.084512
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030829
     * GKs_b in IKs: 0.001874
     * GK1_b in IK1: 0.174811
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 65.843664
     * GKb_b in IKb: 0.003845
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022976
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1080608225
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -22.275656 (After loading)
 - states[40]: 0.000895 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1103380128, states[0] = -94.997339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124936580, states[0] = -95.013186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146003356, states[0] = 34.551768, states[40]= 0.161818
Saving checkpoint... 
Iteration: 1165089572, states[0] = -6.485640, states[40]= 0.003073
Saving checkpoint... 
Iteration: 1185114420, states[0] = -27.729658, states[40]= 0.000645
Saving checkpoint... 
Iteration: 1205422832, states[0] = -95.009992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225897603, states[0] = -95.003076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245955653, states[0] = -95.016837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265846280, states[0] = -94.982808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281491158, states[0] = -95.022227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302185301, states[0] = -94.778124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321388067, states[0] = -94.999946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340348201, states[0] = -94.983702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358948593, states[0] = -95.015447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377142861, states[0] = -55.360952, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1395140364, states[0] = -52.636158, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1412996851, states[0] = -95.022844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431140255, states[0] = -52.518558, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1448779592, states[0] = -94.935778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466371738, states[0] = -94.993922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483790041, states[0] = -94.945305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497294261, states[0] = -94.948876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514301207, states[0] = -95.127787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531367149, states[0] = -95.063889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548602015, states[0] = 44.476921, states[40]= 0.083125
Saving checkpoint... 
Iteration: 1565379508, states[0] = -95.254740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582695821, states[0] = -95.150107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599496693, states[0] = -95.153829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616557839, states[0] = -95.034472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633735421, states[0] = -95.217477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649995820, states[0] = -95.274217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666624090, states[0] = -60.394097, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1683096883, states[0] = -29.643265, states[40]= 0.000522
Saving checkpoint... 
Iteration: 1699675618, states[0] = -95.110390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715981103, states[0] = -95.264090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732708803, states[0] = -95.178723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749004929, states[0] = 29.681461, states[40]= 0.139482
Saving checkpoint... 
Iteration: 1765622214, states[0] = -58.010816, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1782051228, states[0] = 7.992198, states[40]= 0.005588
Saving checkpoint... 
Iteration: 1798601585, states[0] = -34.481503, states[40]= 0.000306
Saving checkpoint... 
Iteration: 1815028157, states[0] = 19.454381, states[40]= 0.005967
Saving checkpoint... 
Iteration: 1831652694, states[0] = -70.012497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1847910422, states[0] = -95.021335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864593254, states[0] = -9.818342, states[40]= 0.002369
Saving checkpoint... 
Iteration: 1879181817, states[0] = -94.755931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895920382, states[0] = -95.012530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912347452, states[0] = -94.985159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929109748, states[0] = -23.703955, states[40]= 0.000834
Saving checkpoint... 
Iteration: 1945503422, states[0] = 34.191998, states[40]= 0.163260
Saving checkpoint... 
Iteration: 1962143666, states[0] = -56.302489, states[40]= 0.000011


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_76.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_76_0_r628217866_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_76_0_r628217866_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.549654
     * GNaL_b in INaL: 0.006926
     * Gto_b in Ito: 0.084512
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030829
     * GKs_b in IKs: 0.001874
     * GK1_b in IK1: 0.174811
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 65.843664
     * GKb_b in IKb: 0.003845
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022976
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1962143666
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -56.302489 (After loading)
 - states[40]: 0.000011 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1981306488, states[0] = -94.958330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998648638, states[0] = -62.005815, states[40]= 0.000004
Saving checkpoint... 
Iteration: 2015854792, states[0] = -94.986384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033213938, states[0] = -94.845991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050208489, states[0] = -94.835844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067248315, states[0] = -94.899808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084515491, states[0] = 22.462576, states[40]= 0.016230
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.898543
 - CaMKt in component CaMK (millimolar): 0.007395
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.748163
 - nass in component intracellular_ions (millimolar): 6.748224
 - ki in component intracellular_ions (millimolar): 145.223203
 - kss in component intracellular_ions (millimolar): 145.223184
 - cansr in component intracellular_ions (millimolar): 1.336850
 - cajsr in component intracellular_ions (millimolar): 1.297922
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003620
 - hf in component INa (dimensionless): 0.879943
 - hs in component INa (dimensionless): 0.879939
 - j in component INa (dimensionless): 0.879909
 - hsp in component INa (dimensionless): 0.725722
 - jp in component INa (dimensionless): 0.879889
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708329
 - hLp in component INaL (dimensionless): 0.447562
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.614370
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.688020
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930441
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999867
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001703
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337160
 - xs1 in component IKs (dimensionless): 0.251976
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:28:02 (13724): called boinc_finish(0)

</stderr_txt>
]]>


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