𝕏

Task 55407997

Name HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_575_0
Workunit 26310739
Created 30 Jun 2024, 6:57:02 UTC
Sent 30 Jun 2024, 8:41:04 UTC
Report deadline 3 Jul 2024, 18:17:04 UTC
Received 1 Jul 2024, 23:55:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220412
Run time 1 hours 47 min 35 sec
CPU time 1 hours 40 min 44 sec
Validate state Valid
Credit 65.46
Device peak FLOPS 3.50 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 9.76 MB
Peak swap size 5.17 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_575.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_575_0_r1231472954_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_575_0_r1231472954_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 119.950622
     * GNaL_b in INaL: 0.005333
     * Gto_b in Ito: 0.091540
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030361
     * GKs_b in IKs: 0.001981
     * GK1_b in IK1: 0.147206
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 73.385133
     * GKb_b in IKb: 0.003680
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018633
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9346236, states[0] = -94.936735, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_575.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_575_0_r1231472954_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_575_0_r1231472954_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 119.950622
     * GNaL_b in INaL: 0.005333
     * Gto_b in Ito: 0.091540
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030361
     * GKs_b in IKs: 0.001981
     * GK1_b in IK1: 0.147206
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 73.385133
     * GKb_b in IKb: 0.003680
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018633
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 9346236
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.936735 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 34269849, states[0] = -94.787565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57222305, states[0] = -94.683064, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_575.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_575_0_r1231472954_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_575_0_r1231472954_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 119.950622
     * GNaL_b in INaL: 0.005333
     * Gto_b in Ito: 0.091540
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030361
     * GKs_b in IKs: 0.001981
     * GK1_b in IK1: 0.147206
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 73.385133
     * GKb_b in IKb: 0.003680
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018633
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 57222305
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.683064 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 82235482, states[0] = -94.693097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104745600, states[0] = -94.703792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127502224, states[0] = 43.954601, states[40]= 0.098752
Saving checkpoint... 
Iteration: 149330704, states[0] = -94.789855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171092111, states[0] = -11.742053, states[40]= 0.001998
Saving checkpoint... 
Iteration: 192375596, states[0] = -94.813266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213613737, states[0] = -31.439556, states[40]= 0.000418
Saving checkpoint... 
Iteration: 234814923, states[0] = -94.776740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255846339, states[0] = -94.798022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276570959, states[0] = 2.522119, states[40]= 0.004535
Saving checkpoint... 
Iteration: 295300211, states[0] = -94.764071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316872295, states[0] = -94.811269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336920662, states[0] = -94.828835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356618831, states[0] = -36.128363, states[40]= 0.000232
Saving checkpoint... 
Iteration: 376392085, states[0] = -94.819393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395726986, states[0] = -94.664849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415163465, states[0] = -86.473884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433921237, states[0] = -94.828927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453072699, states[0] = 1.640413, states[40]= 0.004449
Saving checkpoint... 
Iteration: 471583688, states[0] = -4.982210, states[40]= 0.003404
Saving checkpoint... 
Iteration: 490317900, states[0] = -94.778755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508814565, states[0] = -94.776141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527317768, states[0] = -94.778628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546093747, states[0] = -13.152476, states[40]= 0.001751
Saving checkpoint... 
Iteration: 564702318, states[0] = -94.612953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583520696, states[0] = 20.502061, states[40]= 0.009074
Saving checkpoint... 
Iteration: 601888311, states[0] = -94.817794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620632664, states[0] = -49.480842, states[40]= 0.000031
Saving checkpoint... 
Iteration: 638902389, states[0] = -94.822900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657404327, states[0] = -94.823542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676212537, states[0] = -94.635541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694838941, states[0] = -94.793198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713669055, states[0] = -92.052935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732141656, states[0] = -58.598758, states[40]= 0.000007
Saving checkpoint... 
Iteration: 750836593, states[0] = -94.791677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769397708, states[0] = -94.821180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787909386, states[0] = -94.825106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806768572, states[0] = -94.729581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825299170, states[0] = -94.762730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842925118, states[0] = -94.829736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861373162, states[0] = -94.811277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880036227, states[0] = 16.336062, states[40]= 0.005409
Saving checkpoint... 
Iteration: 898678065, states[0] = -94.330734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917234969, states[0] = -94.679087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936591421, states[0] = -11.105028, states[40]= 0.002118
Saving checkpoint... 
Iteration: 951144754, states[0] = -61.846784, states[40]= 0.000004
Saving checkpoint... 
Iteration: 966516450, states[0] = 21.231065, states[40]= 0.014790
Saving checkpoint... 
Iteration: 987611905, states[0] = -29.746926, states[40]= 0.000499
Saving checkpoint... 
Iteration: 1007158867, states[0] = -79.632866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026353218, states[0] = -94.801294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045351102, states[0] = -94.800119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064235891, states[0] = -94.680603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083074811, states[0] = 0.520411, states[40]= 0.004323
Saving checkpoint... 
Iteration: 1101483148, states[0] = -94.841861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120238333, states[0] = -94.684781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139257889, states[0] = -94.715124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158317415, states[0] = -94.777925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177144751, states[0] = -61.843339, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1191493377, states[0] = -94.843346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210831646, states[0] = -94.788126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229722454, states[0] = -94.655510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248662926, states[0] = -85.722396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267510803, states[0] = 22.198243, states[40]= 0.045491
Saving checkpoint... 
Iteration: 1286581898, states[0] = -3.748830, states[40]= 0.003648
Saving checkpoint... 
Iteration: 1305383848, states[0] = -94.815539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324043979, states[0] = 13.652543, states[40]= 0.005069
Saving checkpoint... 
Iteration: 1343006506, states[0] = 24.927892, states[40]= 0.122668
Saving checkpoint... 
Iteration: 1362028874, states[0] = 18.570522, states[40]= 0.006172
Saving checkpoint... 
Iteration: 1376756063, states[0] = -94.712371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395814241, states[0] = -94.775276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414950770, states[0] = -94.835620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433407119, states[0] = -94.823934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452251901, states[0] = -94.706234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470915304, states[0] = -94.826477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485088720, states[0] = -8.828561, states[40]= 0.002583
Saving checkpoint... 
Iteration: 1504201662, states[0] = 49.798181, states[40]= 0.040887
Saving checkpoint... 
Iteration: 1517549299, states[0] = -93.423480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537772383, states[0] = -95.112292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556821928, states[0] = -60.966298, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1576155745, states[0] = -95.112668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594932391, states[0] = -75.571253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613219624, states[0] = -58.931564, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1631864857, states[0] = -94.929227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650409977, states[0] = -47.925823, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1669043803, states[0] = -91.881679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687589157, states[0] = -25.462042, states[40]= 0.000699
Saving checkpoint... 
Iteration: 1706298010, states[0] = -95.024383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724821691, states[0] = -61.505930, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1743309415, states[0] = 23.670295, states[40]= 0.062852
Saving checkpoint... 
Iteration: 1762127462, states[0] = -95.080645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780583396, states[0] = -19.319068, states[40]= 0.001118
Saving checkpoint... 
Iteration: 1799607337, states[0] = -95.044175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818586123, states[0] = -8.620113, states[40]= 0.002667
Saving checkpoint... 
Iteration: 1837421920, states[0] = -94.855424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855918217, states[0] = -94.842711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874295461, states[0] = -94.767578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892990910, states[0] = -94.847592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911534296, states[0] = 16.927280, states[40]= 0.005550
Saving checkpoint... 
Iteration: 1930285799, states[0] = -94.750385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948873114, states[0] = -94.811424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968067389, states[0] = 4.227626, states[40]= 0.004669
Saving checkpoint... 
Iteration: 1986928019, states[0] = -94.829997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005460170, states[0] = -94.837285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024218759, states[0] = -94.647614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2042997889, states[0] = -94.843402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061728004, states[0] = -94.665600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080426633, states[0] = -94.829269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099215397, states[0] = -94.640546, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.719479
 - CaMKt in component CaMK (millimolar): 0.007182
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.527302
 - nass in component intracellular_ions (millimolar): 6.527363
 - ki in component intracellular_ions (millimolar): 145.446704
 - kss in component intracellular_ions (millimolar): 145.446685
 - cansr in component intracellular_ions (millimolar): 1.326992
 - cajsr in component intracellular_ions (millimolar): 1.288731
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003686
 - hf in component INa (dimensionless): 0.876800
 - hs in component INa (dimensionless): 0.876795
 - j in component INa (dimensionless): 0.876760
 - hsp in component INa (dimensionless): 0.719822
 - jp in component INa (dimensionless): 0.876737
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.703918
 - hLp in component INaL (dimensionless): 0.443126
 - a in component Ito (dimensionless): 0.000631
 - iF in component Ito (dimensionless): 0.999865
 - iS in component Ito (dimensionless): 0.617070
 - ap in component Ito (dimensionless): 0.000322
 - iFp in component Ito (dimensionless): 0.999865
 - iSp in component Ito (dimensionless): 0.691047
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935943
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001665
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.340363
 - xs1 in component IKs (dimensionless): 0.241977
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997385
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:38:15 (30628): called boinc_finish(0)

</stderr_txt>
]]>