𝕏

Task 55407676

Name HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_544_1
Workunit 26310583
Created 30 Jun 2024, 6:56:51 UTC
Sent 30 Jun 2024, 8:41:04 UTC
Report deadline 3 Jul 2024, 18:17:04 UTC
Received 2 Jul 2024, 8:55:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220412
Run time 2 hours 6 min 7 sec
CPU time 2 hours 2 min 9 sec
Validate state Valid
Credit 61.16
Device peak FLOPS 3.50 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 9.72 MB
Peak swap size 5.13 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_544.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_544_1_r1028799488_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_544_1_r1028799488_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.671507
     * GNaL_b in INaL: 0.005353
     * Gto_b in Ito: 0.074467
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030332
     * GKs_b in IKs: 0.001970
     * GK1_b in IK1: 0.181933
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 71.814854
     * GKb_b in IKb: 0.003719
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040786
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12448057, states[0] = -95.168893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28826221, states[0] = -95.096005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45247190, states[0] = -95.015815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61762552, states[0] = -95.020956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77929597, states[0] = -95.093769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94325315, states[0] = -95.055801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110478968, states[0] = -95.095299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126538322, states[0] = 16.230590, states[40]= 0.005567
Saving checkpoint... 
Iteration: 142787616, states[0] = -95.027494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159149116, states[0] = -72.227160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 175388485, states[0] = -95.074699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191699976, states[0] = -94.920633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207979486, states[0] = -95.091753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224386280, states[0] = -95.073612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240692863, states[0] = -94.907566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256986853, states[0] = -95.092428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273302909, states[0] = -95.036644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289753912, states[0] = -94.995678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301173294, states[0] = -94.825652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318268492, states[0] = -95.010035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334366096, states[0] = -95.066993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350642849, states[0] = -63.230950, states[40]= 0.000003
Saving checkpoint... 
Iteration: 366920994, states[0] = -95.081981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383346790, states[0] = -95.059550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399552918, states[0] = 10.586538, states[40]= 0.005072
Saving checkpoint... 
Iteration: 415928455, states[0] = -95.083462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432136288, states[0] = -55.454295, states[40]= 0.000011
Saving checkpoint... 
Iteration: 448388890, states[0] = -95.074097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464649245, states[0] = -72.297184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 481062077, states[0] = 6.709123, states[40]= 0.004897
Saving checkpoint... 
Iteration: 497073688, states[0] = 1.073745, states[40]= 0.004434
Saving checkpoint... 
Iteration: 513375468, states[0] = -95.070022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529602520, states[0] = -21.758217, states[40]= 0.000869
Saving checkpoint... 
Iteration: 545937410, states[0] = -95.085069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562070220, states[0] = 2.882268, states[40]= 0.004626
Saving checkpoint... 
Iteration: 578348855, states[0] = -95.060297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594699605, states[0] = -94.919393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610961686, states[0] = -95.088948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627286808, states[0] = -95.025129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643679066, states[0] = -94.875635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660099146, states[0] = -18.584371, states[40]= 0.001082
Saving checkpoint... 
Iteration: 676515903, states[0] = 22.909885, states[40]= 0.016571
Saving checkpoint... 
Iteration: 692839725, states[0] = -95.056300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709257158, states[0] = -94.998808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725633980, states[0] = -52.883648, states[40]= 0.000017
Saving checkpoint... 
Iteration: 742043607, states[0] = 14.275943, states[40]= 0.005305
Saving checkpoint... 
Iteration: 758289846, states[0] = -95.027325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774781378, states[0] = -95.020808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791099977, states[0] = -19.365994, states[40]= 0.001020
Saving checkpoint... 
Iteration: 807667402, states[0] = -94.502648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823938258, states[0] = -95.085063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840369686, states[0] = -95.067933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856437720, states[0] = -95.084948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872869529, states[0] = -95.067861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889124540, states[0] = -42.885471, states[40]= 0.000084
Saving checkpoint... 
Iteration: 905477020, states[0] = -95.090835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921772356, states[0] = -95.013146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938225614, states[0] = -94.960476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954624297, states[0] = -42.638915, states[40]= 0.000087
Saving checkpoint... 
Iteration: 971165266, states[0] = -94.111032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987372511, states[0] = -95.068791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003819734, states[0] = -95.046197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020026103, states[0] = 20.363933, states[40]= 0.007212
Saving checkpoint... 
Iteration: 1036495119, states[0] = -95.092836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052807722, states[0] = -95.039200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069443919, states[0] = -95.085908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085731829, states[0] = -94.968901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102110940, states[0] = -29.685293, states[40]= 0.000484
Saving checkpoint... 
Iteration: 1118277862, states[0] = -95.017741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134651953, states[0] = -76.947453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150920809, states[0] = -95.081493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167328772, states[0] = -95.050831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183533057, states[0] = 18.146136, states[40]= 0.006013
Saving checkpoint... 
Iteration: 1194982531, states[0] = -95.091340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212114458, states[0] = -33.023394, states[40]= 0.000333
Saving checkpoint... 
Iteration: 1228146768, states[0] = -68.515300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1244382050, states[0] = -95.071648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260587297, states[0] = -7.946042, states[40]= 0.002788
Saving checkpoint... 
Iteration: 1277011438, states[0] = 23.973993, states[40]= 0.037955
Saving checkpoint... 
Iteration: 1293210730, states[0] = -94.937759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309699433, states[0] = -94.918680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325815628, states[0] = -95.043723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342209021, states[0] = -94.934952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358287042, states[0] = -95.024889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374446000, states[0] = -95.086084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390540541, states[0] = 15.445086, states[40]= 0.005440
Saving checkpoint... 
Iteration: 1406866581, states[0] = -95.066544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419501260, states[0] = 48.695088, states[40]= 0.043704
Saving checkpoint... 
Iteration: 1435899662, states[0] = -95.076426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452442603, states[0] = -95.085465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469051505, states[0] = 11.159759, states[40]= 0.005098
Saving checkpoint... 
Iteration: 1485490906, states[0] = -95.092128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502073725, states[0] = -95.272330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518485378, states[0] = -95.182268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535046409, states[0] = -95.277958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551365284, states[0] = -1.341939, states[40]= 0.004595
Saving checkpoint... 
Iteration: 1568096225, states[0] = -95.327435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584512669, states[0] = -95.253206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600993739, states[0] = -95.225176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617410749, states[0] = -49.443325, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1633938227, states[0] = -91.732793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650162906, states[0] = -95.163823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666694497, states[0] = -95.228479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683054051, states[0] = 5.495658, states[40]= 0.005489
Saving checkpoint... 
Iteration: 1699506296, states[0] = 28.549046, states[40]= 0.104637
Saving checkpoint... 
Iteration: 1715994893, states[0] = -95.333082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732466996, states[0] = -95.314442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748942249, states[0] = -95.292485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765473270, states[0] = -95.319130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1781771452, states[0] = -6.827426, states[40]= 0.003412
Saving checkpoint... 
Iteration: 1798295725, states[0] = -32.521741, states[40]= 0.000350
Saving checkpoint... 
Iteration: 1814582512, states[0] = -6.154602, states[40]= 0.003236
Saving checkpoint... 
Iteration: 1831032314, states[0] = 18.069766, states[40]= 0.006081
Saving checkpoint... 
Iteration: 1847364966, states[0] = -95.079044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863822588, states[0] = -95.055446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880250730, states[0] = -94.996416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896647517, states[0] = -70.052712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1912921375, states[0] = -95.083059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929521157, states[0] = 21.690753, states[40]= 0.009352
Saving checkpoint... 
Iteration: 1945963507, states[0] = -95.089131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962482760, states[0] = -95.091333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978909780, states[0] = -95.078815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995549436, states[0] = 11.986184, states[40]= 0.005140
Saving checkpoint... 
Iteration: 2012100821, states[0] = -20.166937, states[40]= 0.000964
Saving checkpoint... 
Iteration: 2028681770, states[0] = -94.883599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044926345, states[0] = -95.082109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061577442, states[0] = -1.061173, states[40]= 0.004143
Saving checkpoint... 
Iteration: 2078051345, states[0] = 11.224117, states[40]= 0.005101
Saving checkpoint... 
Iteration: 2089427975, states[0] = -95.082377, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.968568
 - CaMKt in component CaMK (millimolar): 0.006792
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.523072
 - nass in component intracellular_ions (millimolar): 6.523130
 - ki in component intracellular_ions (millimolar): 145.457291
 - kss in component intracellular_ions (millimolar): 145.457273
 - cansr in component intracellular_ions (millimolar): 1.302231
 - cajsr in component intracellular_ions (millimolar): 1.264494
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003594
 - hf in component INa (dimensionless): 0.881154
 - hs in component INa (dimensionless): 0.881150
 - j in component INa (dimensionless): 0.881125
 - hsp in component INa (dimensionless): 0.728010
 - jp in component INa (dimensionless): 0.881108
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711969
 - hLp in component INaL (dimensionless): 0.454900
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.621915
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.696838
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934018
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999882
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001575
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334909
 - xs1 in component IKs (dimensionless): 0.242089
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997320
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:55:11 (27040): called boinc_finish(0)

</stderr_txt>
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