𝕏

Task 55407648

Name HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_41_1
Workunit 26310569
Created 30 Jun 2024, 6:56:51 UTC
Sent 30 Jun 2024, 8:41:04 UTC
Report deadline 3 Jul 2024, 18:17:04 UTC
Received 2 Jul 2024, 2:22:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220412
Run time 1 hours 49 min 8 sec
CPU time 1 hours 44 min 35 sec
Validate state Valid
Credit 50.84
Device peak FLOPS 3.50 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 9.74 MB
Peak swap size 5.16 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_41.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_41_1_r594545638_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_41_1_r594545638_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 90.710414
     * GNaL_b in INaL: 0.007523
     * Gto_b in Ito: 0.096072
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033385
     * GKs_b in IKs: 0.001950
     * GK1_b in IK1: 0.155535
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 66.814150
     * GKb_b in IKb: 0.003713
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023799
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14301594, states[0] = -94.860410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33070681, states[0] = 4.261368, states[40]= 0.004547
Saving checkpoint... 
Iteration: 47480865, states[0] = -94.898372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67040764, states[0] = 16.009864, states[40]= 0.004711
Saving checkpoint... 
Iteration: 86401399, states[0] = -94.869427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105602155, states[0] = -16.903231, states[40]= 0.001231
Saving checkpoint... 
Iteration: 124727667, states[0] = -94.712181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143058742, states[0] = 9.713687, states[40]= 0.004678
Saving checkpoint... 
Iteration: 161516049, states[0] = 21.574571, states[40]= 0.013371
Saving checkpoint... 
Iteration: 180503708, states[0] = 30.214488, states[40]= 0.188192
Saving checkpoint... 
Iteration: 199163328, states[0] = -83.092757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218113475, states[0] = -26.962791, states[40]= 0.000673
Saving checkpoint... 
Iteration: 236802460, states[0] = -94.809223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255673119, states[0] = -93.277660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274344472, states[0] = -94.839365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292909263, states[0] = -94.867301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311544919, states[0] = 14.731858, states[40]= 0.004664
Saving checkpoint... 
Iteration: 330542099, states[0] = 15.675754, states[40]= 0.004691
Saving checkpoint... 
Iteration: 349824261, states[0] = -94.826314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368774842, states[0] = -94.780980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387625854, states[0] = -38.315379, states[40]= 0.000187
Saving checkpoint... 
Iteration: 406229880, states[0] = -94.714545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424674162, states[0] = -93.613285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443607888, states[0] = -21.944790, states[40]= 0.000891
Saving checkpoint... 
Iteration: 462319571, states[0] = -94.822816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481233120, states[0] = -94.720300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500449732, states[0] = -94.877598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519608933, states[0] = -22.882404, states[40]= 0.000851
Saving checkpoint... 
Iteration: 538279029, states[0] = -94.785613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556833113, states[0] = -94.832131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576064942, states[0] = 7.231956, states[40]= 0.004655
Saving checkpoint... 
Iteration: 594870498, states[0] = -94.852413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614022297, states[0] = 20.863559, states[40]= 0.006815
Saving checkpoint... 
Iteration: 632732969, states[0] = -94.719899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647194405, states[0] = -94.638167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666332224, states[0] = -94.831457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685282374, states[0] = -94.789160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704314627, states[0] = -94.818846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723149792, states[0] = -63.727376, states[40]= 0.000003
Saving checkpoint... 
Iteration: 742171574, states[0] = -92.581287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760984211, states[0] = -94.883620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780418273, states[0] = -94.869560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799657051, states[0] = -73.167638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 818690306, states[0] = -94.622844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837581756, states[0] = -1.009029, states[40]= 0.004031
Saving checkpoint... 
Iteration: 856415603, states[0] = -94.868720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875674892, states[0] = -93.798652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894977786, states[0] = -94.882490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914284066, states[0] = -94.790772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927330514, states[0] = -94.830101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947755355, states[0] = -94.755311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966815002, states[0] = -94.818909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981402819, states[0] = -94.864619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000765775, states[0] = -94.769340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020104911, states[0] = -19.268082, states[40]= 0.001035
Saving checkpoint... 
Iteration: 1039459358, states[0] = -94.879086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058116862, states[0] = -30.013188, states[40]= 0.000520
Saving checkpoint... 
Iteration: 1077138981, states[0] = -51.663421, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1095862145, states[0] = -94.848053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114899457, states[0] = -94.863371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133669263, states[0] = -90.952791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152612351, states[0] = -25.948070, states[40]= 0.000720
Saving checkpoint... 
Iteration: 1171091768, states[0] = -7.859882, states[40]= 0.002741
Saving checkpoint... 
Iteration: 1190081333, states[0] = -0.761212, states[40]= 0.004065
Saving checkpoint... 
Iteration: 1209372870, states[0] = -94.852935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228274332, states[0] = -94.779631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247190985, states[0] = -94.625538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265906279, states[0] = -94.865500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284852491, states[0] = -94.842943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303615260, states[0] = -28.565372, states[40]= 0.000594
Saving checkpoint... 
Iteration: 1322307117, states[0] = -94.812229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341294210, states[0] = -94.800630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360040943, states[0] = 16.053642, states[40]= 0.004710
Saving checkpoint... 
Iteration: 1379065918, states[0] = 6.819805, states[40]= 0.004645
Saving checkpoint... 
Iteration: 1397993068, states[0] = -94.884363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417418365, states[0] = -94.869032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436407982, states[0] = -94.865894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455314015, states[0] = -94.817712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474255433, states[0] = -94.754961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492955485, states[0] = -94.877926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511879010, states[0] = -94.950660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530491852, states[0] = -95.001318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549359494, states[0] = -94.876349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568043251, states[0] = -95.117108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582217478, states[0] = 21.285649, states[40]= 0.012136
Saving checkpoint... 
Iteration: 1597480294, states[0] = -95.164054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617959770, states[0] = 3.381514, states[40]= 0.005129
Saving checkpoint... 
Iteration: 1637418365, states[0] = 21.062584, states[40]= 0.010912
Saving checkpoint... 
Iteration: 1656867452, states[0] = -95.154729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675829909, states[0] = 17.588280, states[40]= 0.006270
Saving checkpoint... 
Iteration: 1694678314, states[0] = -95.165628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1713223757, states[0] = -95.096977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731789118, states[0] = -95.026063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750776955, states[0] = -95.164432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1769344668, states[0] = -95.128334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788250104, states[0] = -95.135333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1806916393, states[0] = -94.926581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821577402, states[0] = 0.351248, states[40]= 0.004253
Saving checkpoint... 
Iteration: 1840497225, states[0] = -94.908618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859531133, states[0] = 18.816259, states[40]= 0.005120
Saving checkpoint... 
Iteration: 1878656811, states[0] = -73.502192, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1897370425, states[0] = -94.855588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916096320, states[0] = -11.730034, states[40]= 0.001965
Saving checkpoint... 
Iteration: 1934813635, states[0] = -94.818367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953283568, states[0] = -94.790091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971933347, states[0] = -94.872941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990587877, states[0] = -4.964275, states[40]= 0.003345
Saving checkpoint... 
Iteration: 2001325072, states[0] = -94.825555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022206900, states[0] = -94.667070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041641325, states[0] = -54.199743, states[40]= 0.000016
Saving checkpoint... 
Iteration: 2060978606, states[0] = -94.881551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080005485, states[0] = 24.930820, states[40]= 0.153128
Saving checkpoint... 
Iteration: 2099053374, states[0] = 11.747094, states[40]= 0.004665
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.760486
 - CaMKt in component CaMK (millimolar): 0.007657
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.759775
 - nass in component intracellular_ions (millimolar): 6.759837
 - ki in component intracellular_ions (millimolar): 145.207106
 - kss in component intracellular_ions (millimolar): 145.207086
 - cansr in component intracellular_ions (millimolar): 1.350350
 - cajsr in component intracellular_ions (millimolar): 1.311102
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003671
 - hf in component INa (dimensionless): 0.877526
 - hs in component INa (dimensionless): 0.877521
 - j in component INa (dimensionless): 0.877487
 - hsp in component INa (dimensionless): 0.721180
 - jp in component INa (dimensionless): 0.877465
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.704450
 - hLp in component INaL (dimensionless): 0.442796
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.613402
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.686779
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931104
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999872
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001742
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326707
 - xs1 in component IKs (dimensionless): 0.252510
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997374
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:05:28 (31028): called boinc_finish(0)

</stderr_txt>
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