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Task 55405686

Name HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_485_0
Workunit 26309632
Created 30 Jun 2024, 6:04:03 UTC
Sent 30 Jun 2024, 8:18:50 UTC
Report deadline 3 Jul 2024, 17:54:50 UTC
Received 2 Jul 2024, 8:15:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234818
Run time 1 hours 11 min 14 sec
CPU time 57 min 41 sec
Validate state Valid
Credit 64.56
Device peak FLOPS 5.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.44 MB
Peak swap size 391.84 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_485.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_485_0_r1587181592_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_485_0_r1587181592_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.701131
     * GNaL_b in INaL: 0.007421
     * Gto_b in Ito: 0.090246
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029801
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.173376
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 69.292811
     * GKb_b in IKb: 0.003711
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021313
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 31676863, states[0] = -94.092149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69794733, states[0] = -94.987595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108751537, states[0] = -94.933030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152804357, states[0] = -94.986340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191442683, states[0] = -95.046515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220091675, states[0] = -4.722179, states[40]= 0.003372
Saving checkpoint... 
Iteration: 248725984, states[0] = -94.890330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280871711, states[0] = -95.024690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319080782, states[0] = 1.593950, states[40]= 0.004334
Saving checkpoint... 
Iteration: 356611903, states[0] = -20.919513, states[40]= 0.000978
Saving checkpoint... 
Iteration: 398494406, states[0] = -95.054873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439725571, states[0] = -94.889412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474391930, states[0] = -95.032151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503578707, states[0] = 2.622363, states[40]= 0.004430
Saving checkpoint... 
Iteration: 532539284, states[0] = 17.581594, states[40]= 0.004894
Saving checkpoint... 
Iteration: 564925775, states[0] = -95.042032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597277919, states[0] = -94.960968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637530206, states[0] = 20.144628, states[40]= 0.005462
Saving checkpoint... 
Iteration: 681698819, states[0] = -94.836801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712421657, states[0] = -95.040867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742714989, states[0] = -94.869971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777016097, states[0] = 22.543414, states[40]= 0.013929
Saving checkpoint... 
Iteration: 816523162, states[0] = 21.654080, states[40]= 0.006880
Saving checkpoint... 
Iteration: 855916953, states[0] = -95.039505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898539680, states[0] = 17.459179, states[40]= 0.004882
Saving checkpoint... 
Iteration: 934615277, states[0] = -23.778109, states[40]= 0.000866
Saving checkpoint... 
Iteration: 968213289, states[0] = -94.866563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005477777, states[0] = -95.052021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042219453, states[0] = -94.878033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083020860, states[0] = 22.019631, states[40]= 0.007988
Saving checkpoint... 
Iteration: 1116225407, states[0] = -94.888598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150036605, states[0] = 18.390668, states[40]= 0.004999
Saving checkpoint... 
Iteration: 1181408468, states[0] = -95.036854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217912061, states[0] = -95.037864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257132032, states[0] = -38.301446, states[40]= 0.000198
Saving checkpoint... 
Iteration: 1297145881, states[0] = -51.899864, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1336918913, states[0] = -95.039659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367984076, states[0] = -95.052685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407008226, states[0] = 23.564649, states[40]= 0.079297
Saving checkpoint... 
Iteration: 1446199260, states[0] = -94.837274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487791780, states[0] = -94.973743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518557059, states[0] = -95.237941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1547603586, states[0] = -95.180387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578385560, states[0] = -14.016523, states[40]= 0.001801
Saving checkpoint... 
Iteration: 1609842163, states[0] = 13.589687, states[40]= 0.005731
Saving checkpoint... 
Iteration: 1646075409, states[0] = -95.290180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681435341, states[0] = -95.246677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1718044172, states[0] = -95.258184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750714290, states[0] = -95.214559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772558764, states[0] = -94.964003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799175654, states[0] = -5.302166, states[40]= 0.003729
Saving checkpoint... 
Iteration: 1835598598, states[0] = -10.952128, states[40]= 0.002108
Saving checkpoint... 
Iteration: 1870637180, states[0] = -43.685749, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1904359164, states[0] = -95.020677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938966900, states[0] = -95.050481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967324241, states[0] = -94.998822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998717169, states[0] = -94.873177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032090572, states[0] = -3.993518, states[40]= 0.003514
Saving checkpoint... 
Iteration: 2067755848, states[0] = -94.933988, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.930079
 - CaMKt in component CaMK (millimolar): 0.007584
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.628688
 - nass in component intracellular_ions (millimolar): 6.628750
 - ki in component intracellular_ions (millimolar): 145.341441
 - kss in component intracellular_ions (millimolar): 145.341421
 - cansr in component intracellular_ions (millimolar): 1.339853
 - cajsr in component intracellular_ions (millimolar): 1.299989
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003608
 - hf in component INa (dimensionless): 0.880490
 - hs in component INa (dimensionless): 0.880485
 - j in component INa (dimensionless): 0.880454
 - hsp in component INa (dimensionless): 0.726750
 - jp in component INa (dimensionless): 0.880433
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.707430
 - hLp in component INaL (dimensionless): 0.443637
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.607824
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.680309
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.925235
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999848
 - jca in component ICaL (dimensionless): 0.999970
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001706
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.340922
 - xs1 in component IKs (dimensionless): 0.263320
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997330
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:15:05 (5566): called boinc_finish(0)

</stderr_txt>
]]>


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