𝕏

Task 55405279

Name HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_249_1
Workunit 26309428
Created 30 Jun 2024, 6:03:48 UTC
Sent 30 Jun 2024, 8:16:34 UTC
Report deadline 3 Jul 2024, 17:52:34 UTC
Received 2 Jul 2024, 8:06:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234818
Run time 1 hours 11 min 11 sec
CPU time 57 min 18 sec
Validate state Valid
Credit 63.92
Device peak FLOPS 5.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.56 MB
Peak swap size 391.85 GB
Peak disk usage 0.25 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_249.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_249_1_r709499654_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_249_1_r709499654_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.551448
     * GNaL_b in INaL: 0.004576
     * Gto_b in Ito: 0.071411
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033859
     * GKs_b in IKs: 0.001902
     * GK1_b in IK1: 0.157040
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 75.228824
     * GKb_b in IKb: 0.003902
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036114
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 43685258, states[0] = -94.903288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82114549, states[0] = -43.401297, states[40]= 0.000069
Saving checkpoint... 
Iteration: 115613374, states[0] = -41.541155, states[40]= 0.000092
Saving checkpoint... 
Iteration: 143716770, states[0] = -94.919571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173264801, states[0] = -94.983855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204638130, states[0] = -70.505377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 238824702, states[0] = -95.030571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272889511, states[0] = -95.058523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313540432, states[0] = 14.270241, states[40]= 0.005504
Saving checkpoint... 
Iteration: 354865447, states[0] = -95.049961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388749658, states[0] = -94.965393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417729044, states[0] = -94.936965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449974593, states[0] = -95.076821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486207065, states[0] = -94.899516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525583528, states[0] = -10.150584, states[40]= 0.002366
Saving checkpoint... 
Iteration: 564886956, states[0] = -95.057501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607154646, states[0] = -93.069133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639085401, states[0] = -11.953755, states[40]= 0.002009
Saving checkpoint... 
Iteration: 670791724, states[0] = -95.007539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698073373, states[0] = -1.974040, states[40]= 0.004049
Saving checkpoint... 
Iteration: 731531745, states[0] = 17.695806, states[40]= 0.006259
Saving checkpoint... 
Iteration: 766311744, states[0] = -95.022109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804279636, states[0] = -94.997106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848253965, states[0] = -94.970355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888097326, states[0] = -24.256740, states[40]= 0.000689
Saving checkpoint... 
Iteration: 916333617, states[0] = -95.035025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950454157, states[0] = -95.073349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984426953, states[0] = -95.068005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018400211, states[0] = -95.061262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064976245, states[0] = -95.076719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106982443, states[0] = -95.077538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140076121, states[0] = -3.907559, states[40]= 0.003696
Saving checkpoint... 
Iteration: 1171940620, states[0] = -95.070747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211517123, states[0] = 22.270367, states[40]= 0.014047
Saving checkpoint... 
Iteration: 1247683036, states[0] = -94.849345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285708411, states[0] = -94.901595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321199970, states[0] = -94.885310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358538914, states[0] = 14.894738, states[40]= 0.005595
Saving checkpoint... 
Iteration: 1394563221, states[0] = 3.932013, states[40]= 0.004770
Saving checkpoint... 
Iteration: 1434287187, states[0] = -95.003382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471146009, states[0] = -83.101757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509236299, states[0] = -95.264278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1545503204, states[0] = -95.249975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580523426, states[0] = -78.691269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615931867, states[0] = -91.932478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648930794, states[0] = -90.975259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686293185, states[0] = -95.368073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720598881, states[0] = -44.675734, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1750335243, states[0] = -93.935472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1778010005, states[0] = -95.279725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813140492, states[0] = -79.231026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847714006, states[0] = -94.929837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879705093, states[0] = -94.902119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914410350, states[0] = -95.065976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938806091, states[0] = -95.018812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963182407, states[0] = -94.848061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995405516, states[0] = -95.062387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036157529, states[0] = -94.045339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2074599565, states[0] = -26.600550, states[40]= 0.000573
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.954972
 - CaMKt in component CaMK (millimolar): 0.006452
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.383601
 - nass in component intracellular_ions (millimolar): 6.383660
 - ki in component intracellular_ions (millimolar): 145.600531
 - kss in component intracellular_ions (millimolar): 145.600511
 - cansr in component intracellular_ions (millimolar): 1.285571
 - cajsr in component intracellular_ions (millimolar): 1.248953
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003599
 - hf in component INa (dimensionless): 0.880919
 - hs in component INa (dimensionless): 0.880915
 - j in component INa (dimensionless): 0.880887
 - hsp in component INa (dimensionless): 0.727565
 - jp in component INa (dimensionless): 0.880869
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713551
 - hLp in component INaL (dimensionless): 0.460475
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.631734
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.708520
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940087
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999905
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001511
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.321307
 - xs1 in component IKs (dimensionless): 0.227044
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997323
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:04:25 (5464): called boinc_finish(0)

</stderr_txt>
]]>