𝕏

Task 55404143

Name HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_720_0
Workunit 26308861
Created 30 Jun 2024, 6:03:02 UTC
Sent 30 Jun 2024, 8:04:50 UTC
Report deadline 3 Jul 2024, 17:40:50 UTC
Received 3 Jul 2024, 3:51:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241013
Run time 2 hours 15 min 5 sec
CPU time 2 hours 14 min 27 sec
Validate state Valid
Credit 63.88
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_720.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_720_0_r234269009_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_720_0_r234269009_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 113.690987
     * GNaL_b in INaL: 0.007376
     * Gto_b in Ito: 0.085009
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032478
     * GKs_b in IKs: 0.002111
     * GK1_b in IK1: 0.147543
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 73.709006
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.024611
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12348251, states[0] = -95.015167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24423315, states[0] = -94.999478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36355556, states[0] = -94.948381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48147050, states[0] = -67.197687, states[40]= 0.000002
Saving checkpoint... 
Iteration: 60401279, states[0] = -94.940558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72386014, states[0] = -94.927793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84460350, states[0] = -94.943541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96291056, states[0] = -94.858898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108246741, states[0] = -94.801402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120395742, states[0] = -94.918958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132385582, states[0] = -94.914027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144323553, states[0] = -94.880128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156462027, states[0] = -94.933906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168504405, states[0] = 31.006106, states[40]= 0.156408
Saving checkpoint... 
Iteration: 180601440, states[0] = -18.515292, states[40]= 0.001096
Saving checkpoint... 
Iteration: 192457148, states[0] = -94.932099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204424037, states[0] = -94.924244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216582590, states[0] = -2.830086, states[40]= 0.003836
Saving checkpoint... 
Iteration: 228198288, states[0] = -94.702092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240413321, states[0] = -94.920962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252264939, states[0] = -94.821545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264299722, states[0] = -94.859142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276239854, states[0] = -94.784800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288058347, states[0] = 9.299847, states[40]= 0.004932
Saving checkpoint... 
Iteration: 299983351, states[0] = -94.936214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311515252, states[0] = 22.672819, states[40]= 0.018007
Saving checkpoint... 
Iteration: 323517031, states[0] = 22.396676, states[40]= 0.013682
Saving checkpoint... 
Iteration: 335662819, states[0] = -87.136634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347529758, states[0] = 19.543638, states[40]= 0.006138
Saving checkpoint... 
Iteration: 359370798, states[0] = -94.905065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371222709, states[0] = -94.753954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383211145, states[0] = -94.730498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395290123, states[0] = -94.849916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406871108, states[0] = -94.905171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418998952, states[0] = -94.938351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431198784, states[0] = -94.702993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443187326, states[0] = -94.666110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455296116, states[0] = -94.855655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467322251, states[0] = -94.877151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479393149, states[0] = -94.914032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491470100, states[0] = -94.933892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503448904, states[0] = -94.929766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515602609, states[0] = -19.573710, states[40]= 0.001017
Saving checkpoint... 
Iteration: 527369967, states[0] = -94.904577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539400349, states[0] = -94.916522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551547867, states[0] = 13.398415, states[40]= 0.005055
Saving checkpoint... 
Iteration: 563413512, states[0] = -94.920707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575494165, states[0] = -94.937600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587675415, states[0] = -94.323744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599530867, states[0] = 19.221538, states[40]= 0.005988
Saving checkpoint... 
Iteration: 611558455, states[0] = 9.256042, states[40]= 0.004931
Saving checkpoint... 
Iteration: 623625651, states[0] = -41.346197, states[40]= 0.000114
Saving checkpoint... 
Iteration: 635426178, states[0] = -94.924239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647542351, states[0] = 15.425529, states[40]= 0.005188
Saving checkpoint... 
Iteration: 659306069, states[0] = -94.864380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671201273, states[0] = -94.708629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683325515, states[0] = -94.879323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695271275, states[0] = -94.829066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707243598, states[0] = -94.790559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719322210, states[0] = -94.876956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731274194, states[0] = -94.832506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743324093, states[0] = -94.878285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755405417, states[0] = -94.918060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767234000, states[0] = -94.774488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779263889, states[0] = -94.819771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791366199, states[0] = -94.902666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803191150, states[0] = -94.682056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815352516, states[0] = -94.895782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827350868, states[0] = -94.894884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838977108, states[0] = -94.934853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851119845, states[0] = -35.669681, states[40]= 0.000254
Saving checkpoint... 
Iteration: 863046018, states[0] = 14.088192, states[40]= 0.005090
Saving checkpoint... 
Iteration: 874778924, states[0] = -94.837810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886895097, states[0] = -94.914467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898731533, states[0] = -94.770038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910978075, states[0] = -94.934964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923043645, states[0] = 14.958855, states[40]= 0.005148
Saving checkpoint... 
Iteration: 934877240, states[0] = -94.907494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946997230, states[0] = -94.937777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958974702, states[0] = -94.934376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970933127, states[0] = -94.925809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983084833, states[0] = -4.342161, states[40]= 0.003548
Saving checkpoint... 
Iteration: 994990479, states[0] = -94.936806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007001724, states[0] = 48.281257, states[40]= 0.072101
Saving checkpoint... 
Iteration: 1019079129, states[0] = -0.674642, states[40]= 0.004185
Saving checkpoint... 
Iteration: 1030941546, states[0] = -94.927786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043001930, states[0] = 46.632296, states[40]= 0.083886
Saving checkpoint... 
Iteration: 1054931435, states[0] = -94.925330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066687856, states[0] = -94.668476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078778447, states[0] = -94.837144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090935577, states[0] = -94.926334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102801315, states[0] = -94.859969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114862414, states[0] = -94.900644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126994833, states[0] = -94.937333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138822301, states[0] = -94.876747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150907679, states[0] = -94.918526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162834899, states[0] = -94.885260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174949321, states[0] = -94.929417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187046908, states[0] = 13.757382, states[40]= 0.005072
Saving checkpoint... 
Iteration: 1198915956, states[0] = -94.921017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210951768, states[0] = -94.929910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223078893, states[0] = -0.535684, states[40]= 0.004205
Saving checkpoint... 
Iteration: 1234932538, states[0] = -94.925490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246715165, states[0] = -94.738317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258762012, states[0] = -94.816994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270645631, states[0] = -63.042220, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1282758524, states[0] = -94.812278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294666844, states[0] = -91.438737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306695660, states[0] = -94.694736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318805527, states[0] = -94.863488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330647617, states[0] = -65.400991, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1342673334, states[0] = -94.062478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354517446, states[0] = 22.329717, states[40]= 0.012938
Saving checkpoint... 
Iteration: 1366068768, states[0] = 4.747145, states[40]= 0.004736
Saving checkpoint... 
Iteration: 1378160934, states[0] = -84.399021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390144847, states[0] = -62.130664, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1401813990, states[0] = -94.870338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413898350, states[0] = -94.915265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425762191, states[0] = -94.817122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437831361, states[0] = -94.882791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449961932, states[0] = -94.931777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461875774, states[0] = -94.906526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473919019, states[0] = -94.921722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485851139, states[0] = -94.894601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497823248, states[0] = -94.877191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509646064, states[0] = 11.214308, states[40]= 0.005797
Saving checkpoint... 
Iteration: 1521372179, states[0] = -5.034411, states[40]= 0.003815
Saving checkpoint... 
Iteration: 1533397004, states[0] = -31.009746, states[40]= 0.000433
Saving checkpoint... 
Iteration: 1545232871, states[0] = -95.164175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557279396, states[0] = -95.225851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568995472, states[0] = -95.243722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580902331, states[0] = -95.124040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592898214, states[0] = -95.117322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604747840, states[0] = 9.483158, states[40]= 0.005766
Saving checkpoint... 
Iteration: 1616494699, states[0] = -29.822258, states[40]= 0.000489
Saving checkpoint... 
Iteration: 1628500469, states[0] = -36.051302, states[40]= 0.000239
Saving checkpoint... 
Iteration: 1640048853, states[0] = -95.206233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652192983, states[0] = -28.048544, states[40]= 0.000576
Saving checkpoint... 
Iteration: 1664206088, states[0] = -42.339230, states[40]= 0.000100
Saving checkpoint... 
Iteration: 1675979314, states[0] = -95.075558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688075756, states[0] = -95.236255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700114419, states[0] = 22.991882, states[40]= 0.022613
Saving checkpoint... 
Iteration: 1712003171, states[0] = -95.132098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724042881, states[0] = -95.199222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735842785, states[0] = 11.992005, states[40]= 0.005995
Saving checkpoint... 
Iteration: 1747879675, states[0] = -13.834704, states[40]= 0.001865
Saving checkpoint... 
Iteration: 1759977029, states[0] = -95.069570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771854152, states[0] = 6.047541, states[40]= 0.005507
Saving checkpoint... 
Iteration: 1783908835, states[0] = -45.543688, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1795591285, states[0] = -26.260211, states[40]= 0.000668
Saving checkpoint... 
Iteration: 1807434150, states[0] = -94.990210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819466376, states[0] = -94.979874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831393888, states[0] = -94.946973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843251014, states[0] = -94.824974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855333095, states[0] = -94.899958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866900706, states[0] = -94.927203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878574650, states[0] = 1.638580, states[40]= 0.004482
Saving checkpoint... 
Iteration: 1890589556, states[0] = -8.114484, states[40]= 0.002750
Saving checkpoint... 
Iteration: 1902302437, states[0] = -94.864335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914314938, states[0] = -94.873433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926318378, states[0] = -94.875209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937946636, states[0] = -94.929623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949731126, states[0] = -94.769518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961658884, states[0] = -81.254235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973640913, states[0] = -57.700407, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1985367055, states[0] = -94.902552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997200492, states[0] = -94.706129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009277944, states[0] = -94.836072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021255612, states[0] = -94.807793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033114436, states[0] = -30.566807, states[40]= 0.000468
Saving checkpoint... 
Iteration: 2045241930, states[0] = -94.786997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057242801, states[0] = -94.788378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068515083, states[0] = 22.698713, states[40]= 0.018538
Saving checkpoint... 
Iteration: 2080240196, states[0] = -94.784106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092068519, states[0] = 4.864017, states[40]= 0.004743
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.813223
 - CaMKt in component CaMK (millimolar): 0.007159
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.519959
 - nass in component intracellular_ions (millimolar): 6.520021
 - ki in component intracellular_ions (millimolar): 145.454996
 - kss in component intracellular_ions (millimolar): 145.454975
 - cansr in component intracellular_ions (millimolar): 1.323829
 - cajsr in component intracellular_ions (millimolar): 1.285367
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003651
 - hf in component INa (dimensionless): 0.878454
 - hs in component INa (dimensionless): 0.878449
 - j in component INa (dimensionless): 0.878416
 - hsp in component INa (dimensionless): 0.722919
 - jp in component INa (dimensionless): 0.878394
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.706596
 - hLp in component INaL (dimensionless): 0.446461
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.617188
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.690857
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931802
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999875
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001656
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.343896
 - xs1 in component IKs (dimensionless): 0.247845
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997360
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:51:22 (166056): called boinc_finish(0)

</stderr_txt>
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