𝕏

Task 55403361

Name HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_200_1
Workunit 26308471
Created 30 Jun 2024, 6:02:36 UTC
Sent 30 Jun 2024, 7:51:30 UTC
Report deadline 3 Jul 2024, 17:27:30 UTC
Received 30 Jun 2024, 23:07:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235804
Run time 1 hours 15 min 29 sec
CPU time 1 hours 13 min 15 sec
Validate state Valid
Credit 60.13
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.25 MB
Peak swap size 5.32 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_200.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_200_1_r1093655202_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_200_1_r1093655202_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 115.816362
     * GNaL_b in INaL: 0.004896
     * Gto_b in Ito: 0.099970
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032030
     * GKs_b in IKs: 0.001815
     * GK1_b in IK1: 0.149873
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 70.014971
     * GKb_b in IKb: 0.003773
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049899
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8831780, states[0] = -95.045961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27446850, states[0] = -95.029017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46656429, states[0] = -86.888678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65288131, states[0] = -94.916539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79199859, states[0] = -94.780535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98187690, states[0] = -94.746225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117064978, states[0] = 4.351885, states[40]= 0.004538
Saving checkpoint... 
Iteration: 136309942, states[0] = -94.918562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154989833, states[0] = -94.979714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174245090, states[0] = -94.849756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192890694, states[0] = -94.957455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211501888, states[0] = 45.711608, states[40]= 0.075771
Saving checkpoint... 
Iteration: 230316289, states[0] = -94.920943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249228668, states[0] = -94.823611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268059845, states[0] = 6.664020, states[40]= 0.004646
Saving checkpoint... 
Iteration: 287344753, states[0] = -94.937801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306487073, states[0] = -94.978011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325661861, states[0] = -90.835666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344412092, states[0] = -94.963389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363231821, states[0] = -94.828670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381848732, states[0] = -94.939735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400722900, states[0] = -94.813470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419397164, states[0] = -94.958979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438365860, states[0] = -94.947555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457437627, states[0] = -94.969474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476129054, states[0] = -49.831664, states[40]= 0.000026
Saving checkpoint... 
Iteration: 495055354, states[0] = 8.493462, states[40]= 0.004704
Saving checkpoint... 
Iteration: 513703971, states[0] = -94.776866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532453737, states[0] = -94.972614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551235850, states[0] = -94.834973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570229616, states[0] = -94.824900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589416953, states[0] = -94.964513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608157525, states[0] = -85.530353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627753428, states[0] = -94.860103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647138223, states[0] = -59.579083, states[40]= 0.000005
Saving checkpoint... 
Iteration: 666273903, states[0] = -94.884187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685794669, states[0] = -94.903930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704723797, states[0] = -94.814852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724336358, states[0] = -94.932956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743232655, states[0] = -94.829767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762078259, states[0] = -2.640970, states[40]= 0.003752
Saving checkpoint... 
Iteration: 781084037, states[0] = -6.727448, states[40]= 0.002966
Saving checkpoint... 
Iteration: 800179931, states[0] = -94.698120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819219160, states[0] = -94.806439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838681514, states[0] = -94.711118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857848502, states[0] = -94.939304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877338543, states[0] = -94.934070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896440524, states[0] = -94.969794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915289755, states[0] = -94.899477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934368363, states[0] = -94.948270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953055022, states[0] = 8.624971, states[40]= 0.004707
Saving checkpoint... 
Iteration: 972102892, states[0] = -23.991017, states[40]= 0.000718
Saving checkpoint... 
Iteration: 991213067, states[0] = -94.794829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010001247, states[0] = 50.378113, states[40]= 0.038726
Saving checkpoint... 
Iteration: 1029034858, states[0] = 15.876878, states[40]= 0.005303
Saving checkpoint... 
Iteration: 1047809752, states[0] = -94.915628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066397352, states[0] = -94.958610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084949043, states[0] = -94.971369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103681113, states[0] = -94.708030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122535208, states[0] = 15.765453, states[40]= 0.005277
Saving checkpoint... 
Iteration: 1141465165, states[0] = -94.974196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160421236, states[0] = -94.965225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179127514, states[0] = -48.224089, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1198438347, states[0] = -94.969137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217450838, states[0] = -94.971623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236595971, states[0] = -17.364210, states[40]= 0.001158
Saving checkpoint... 
Iteration: 1255021987, states[0] = 19.255069, states[40]= 0.007992
Saving checkpoint... 
Iteration: 1274076834, states[0] = -1.750189, states[40]= 0.003896
Saving checkpoint... 
Iteration: 1293041401, states[0] = 13.682889, states[40]= 0.004956
Saving checkpoint... 
Iteration: 1312244611, states[0] = -94.847584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331324318, states[0] = -94.925368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350337445, states[0] = -94.933150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369090465, states[0] = -12.195814, states[40]= 0.001874
Saving checkpoint... 
Iteration: 1387704304, states[0] = -94.776976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406400364, states[0] = -94.959313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425119567, states[0] = -40.127068, states[40]= 0.000118
Saving checkpoint... 
Iteration: 1443904711, states[0] = -94.960581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462913215, states[0] = -94.962949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481721188, states[0] = -94.809688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500612470, states[0] = 21.682620, states[40]= 0.032769
Saving checkpoint... 
Iteration: 1513624433, states[0] = -66.829757, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1532144152, states[0] = 9.913716, states[40]= 0.005601
Saving checkpoint... 
Iteration: 1551163569, states[0] = -95.068211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1569819464, states[0] = -95.200565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582700796, states[0] = -95.170992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601302518, states[0] = -95.177267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619846632, states[0] = -94.712110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638508468, states[0] = -95.190755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656854588, states[0] = -95.255693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676570210, states[0] = -95.106416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1695612720, states[0] = 21.171198, states[40]= 0.030588
Saving checkpoint... 
Iteration: 1714626009, states[0] = -73.310468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1733483865, states[0] = -22.700673, states[40]= 0.000817
Saving checkpoint... 
Iteration: 1752295684, states[0] = -95.291520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770883498, states[0] = -95.282612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789580674, states[0] = -19.132668, states[40]= 0.001102
Saving checkpoint... 
Iteration: 1809095083, states[0] = -19.913189, states[40]= 0.000965
Saving checkpoint... 
Iteration: 1827321587, states[0] = -94.961456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846126274, states[0] = -48.267606, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1864923162, states[0] = -94.977757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880363868, states[0] = -94.953683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899123280, states[0] = -44.131862, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1917643288, states[0] = -65.482837, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1936529614, states[0] = 17.425296, states[40]= 0.005844
Saving checkpoint... 
Iteration: 1955096924, states[0] = -18.319179, states[40]= 0.001068
Saving checkpoint... 
Iteration: 1973316280, states[0] = -94.920109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991931163, states[0] = -94.967281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010753776, states[0] = -94.859758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029139518, states[0] = -61.005905, states[40]= 0.000004
Saving checkpoint... 
Iteration: 2047958397, states[0] = -94.972449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066731480, states[0] = -94.826955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085419501, states[0] = -94.964140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098209364, states[0] = -94.786765, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.854261
 - CaMKt in component CaMK (millimolar): 0.006905
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.580298
 - nass in component intracellular_ions (millimolar): 6.580357
 - ki in component intracellular_ions (millimolar): 145.398998
 - kss in component intracellular_ions (millimolar): 145.398978
 - cansr in component intracellular_ions (millimolar): 1.302732
 - cajsr in component intracellular_ions (millimolar): 1.264906
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003636
 - hf in component INa (dimensionless): 0.879173
 - hs in component INa (dimensionless): 0.879168
 - j in component INa (dimensionless): 0.879138
 - hsp in component INa (dimensionless): 0.724271
 - jp in component INa (dimensionless): 0.879118
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708723
 - hLp in component INaL (dimensionless): 0.450690
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622492
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.697913
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940000
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999897
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001553
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.323621
 - xs1 in component IKs (dimensionless): 0.235774
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997350
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:34:55 (18952): called boinc_finish(0)

</stderr_txt>
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