𝕏

Task 55403254

Name HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_496_0
Workunit 26308418
Created 30 Jun 2024, 6:02:31 UTC
Sent 30 Jun 2024, 7:50:01 UTC
Report deadline 3 Jul 2024, 17:26:01 UTC
Received 1 Jul 2024, 2:07:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235062
Run time 52 min 3 sec
CPU time 50 min 17 sec
Validate state Valid
Credit 61.46
Device peak FLOPS 5.41 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.57 MB
Peak swap size 6.19 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_496.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_496_0_r2046319053_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_496_0_r2046319053_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 116.308203
     * GNaL_b in INaL: 0.006843
     * Gto_b in Ito: 0.085731
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032955
     * GKs_b in IKs: 0.002132
     * GK1_b in IK1: 0.148638
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 74.755530
     * GKb_b in IKb: 0.003844
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019184
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14028165, states[0] = 18.408840, states[40]= 0.006504
Saving checkpoint... 
Iteration: 27466707, states[0] = -95.096473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40521221, states[0] = 20.876688, states[40]= 0.008912
Saving checkpoint... 
Iteration: 55490315, states[0] = -95.055497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69541734, states[0] = 14.870455, states[40]= 0.005241
Saving checkpoint... 
Iteration: 83229010, states[0] = -94.869418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97036294, states[0] = 16.932994, states[40]= 0.005531
Saving checkpoint... 
Iteration: 110929508, states[0] = -95.018945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124907124, states[0] = -95.010637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139104514, states[0] = -23.526704, states[40]= 0.000778
Saving checkpoint... 
Iteration: 152187486, states[0] = -94.765794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165751431, states[0] = -94.893711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179867269, states[0] = -94.992375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193433338, states[0] = -95.014786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207263626, states[0] = -94.909520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221325704, states[0] = -94.968366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234504337, states[0] = 31.232356, states[40]= 0.151594
Saving checkpoint... 
Iteration: 248154439, states[0] = -79.411328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262570219, states[0] = 3.249846, states[40]= 0.004622
Saving checkpoint... 
Iteration: 276719428, states[0] = -94.838126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290430532, states[0] = -95.013584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304405075, states[0] = -95.006255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318240167, states[0] = -94.875276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332582686, states[0] = -4.060084, states[40]= 0.003601
Saving checkpoint... 
Iteration: 345951350, states[0] = -95.018345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359810173, states[0] = -94.956568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373103628, states[0] = -22.564791, states[40]= 0.000825
Saving checkpoint... 
Iteration: 386158632, states[0] = -86.024737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397335404, states[0] = -94.974408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409227674, states[0] = -94.853671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421121211, states[0] = -39.606887, states[40]= 0.000139
Saving checkpoint... 
Iteration: 432891636, states[0] = -95.001540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444888766, states[0] = -95.000468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456304844, states[0] = -94.952129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468435099, states[0] = -95.014587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481123076, states[0] = -41.508316, states[40]= 0.000106
Saving checkpoint... 
Iteration: 494464434, states[0] = -95.020829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507834757, states[0] = -94.973934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521130150, states[0] = -49.034337, states[40]= 0.000033
Saving checkpoint... 
Iteration: 534489926, states[0] = -95.025002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548544795, states[0] = 13.986621, states[40]= 0.005136
Saving checkpoint... 
Iteration: 561733411, states[0] = -94.863789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574942922, states[0] = -95.016361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588744818, states[0] = -94.882465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602674425, states[0] = -94.578979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616949543, states[0] = -95.017791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630642265, states[0] = -62.719878, states[40]= 0.000003
Saving checkpoint... 
Iteration: 643837401, states[0] = -94.975490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657322241, states[0] = -94.965478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671433565, states[0] = -95.014085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685182140, states[0] = -94.737597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699483379, states[0] = -95.023918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712304914, states[0] = -94.952030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725503617, states[0] = 34.513766, states[40]= 0.144769
Saving checkpoint... 
Iteration: 739205232, states[0] = -94.808144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752057560, states[0] = 8.970497, states[40]= 0.004925
Saving checkpoint... 
Iteration: 765237680, states[0] = -94.870906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778689571, states[0] = -94.770281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791545005, states[0] = 13.908027, states[40]= 0.005130
Saving checkpoint... 
Iteration: 804133564, states[0] = -52.803069, states[40]= 0.000018
Saving checkpoint... 
Iteration: 815782655, states[0] = -94.930956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828292371, states[0] = -94.940699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840361080, states[0] = -94.988338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853561914, states[0] = 7.117405, states[40]= 0.004856
Saving checkpoint... 
Iteration: 866142709, states[0] = -63.247536, states[40]= 0.000003
Saving checkpoint... 
Iteration: 878944032, states[0] = -95.016424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891596167, states[0] = -15.452879, states[40]= 0.001413
Saving checkpoint... 
Iteration: 905106900, states[0] = -25.686582, states[40]= 0.000678
Saving checkpoint... 
Iteration: 919448105, states[0] = -95.017296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933641645, states[0] = -61.987966, states[40]= 0.000004
Saving checkpoint... 
Iteration: 948075553, states[0] = 0.421739, states[40]= 0.004328
Saving checkpoint... 
Iteration: 962531009, states[0] = 18.730515, states[40]= 0.006046
Saving checkpoint... 
Iteration: 976451090, states[0] = -95.017897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989910319, states[0] = -95.007467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003260644, states[0] = -94.904844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016745733, states[0] = -94.883609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030179688, states[0] = -94.713951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043878586, states[0] = -94.996084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057571016, states[0] = 2.849583, states[40]= 0.004587
Saving checkpoint... 
Iteration: 1071212453, states[0] = -94.823436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085062220, states[0] = 6.983482, states[40]= 0.004851
Saving checkpoint... 
Iteration: 1099042939, states[0] = 14.675788, states[40]= 0.005193
Saving checkpoint... 
Iteration: 1112571116, states[0] = 2.798727, states[40]= 0.004583
Saving checkpoint... 
Iteration: 1126427159, states[0] = -95.012171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140684057, states[0] = -94.749144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154684878, states[0] = -94.753164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167984247, states[0] = -95.023762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181801483, states[0] = -94.948798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195270687, states[0] = -94.917311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209163208, states[0] = -91.345885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222563834, states[0] = 6.267620, states[40]= 0.004817
Saving checkpoint... 
Iteration: 1236343470, states[0] = -94.978734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250141891, states[0] = -62.277224, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1264169155, states[0] = -94.022436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277791147, states[0] = -94.939245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291406649, states[0] = -95.006133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305234020, states[0] = -94.864379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319158702, states[0] = -86.125522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332863553, states[0] = -94.989226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346945429, states[0] = -95.016447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360592052, states[0] = -11.636098, states[40]= 0.002024
Saving checkpoint... 
Iteration: 1374476348, states[0] = -95.022375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388462409, states[0] = -95.019899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402249658, states[0] = -94.889272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415405239, states[0] = -95.005606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429183410, states[0] = -94.745401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443547695, states[0] = 12.890196, states[40]= 0.005067
Saving checkpoint... 
Iteration: 1457993997, states[0] = -95.025013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471980814, states[0] = -95.023039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486244503, states[0] = -94.881420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500076014, states[0] = -2.314749, states[40]= 0.003968
Saving checkpoint... 
Iteration: 1514127790, states[0] = 18.818774, states[40]= 0.007737
Saving checkpoint... 
Iteration: 1527383963, states[0] = -18.665804, states[40]= 0.001174
Saving checkpoint... 
Iteration: 1539423037, states[0] = -64.901808, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1551747682, states[0] = -94.583721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564303172, states[0] = -41.073646, states[40]= 0.000114
Saving checkpoint... 
Iteration: 1577860492, states[0] = -95.093462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591115616, states[0] = -95.237909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605141099, states[0] = -92.599278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618807299, states[0] = 26.207448, states[40]= 0.094689
Saving checkpoint... 
Iteration: 1632230067, states[0] = -95.265245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645843623, states[0] = 11.039075, states[40]= 0.005938
Saving checkpoint... 
Iteration: 1659622062, states[0] = 20.387614, states[40]= 0.009807
Saving checkpoint... 
Iteration: 1672954089, states[0] = -95.035182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1685917179, states[0] = -95.245055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699275395, states[0] = -11.001687, states[40]= 0.002433
Saving checkpoint... 
Iteration: 1712786200, states[0] = -22.766720, states[40]= 0.000846
Saving checkpoint... 
Iteration: 1726662100, states[0] = -95.109321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1740450925, states[0] = -94.941197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1754971106, states[0] = -95.316650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768579107, states[0] = -14.965303, states[40]= 0.001670
Saving checkpoint... 
Iteration: 1782769311, states[0] = -95.134917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1795910037, states[0] = -49.872891, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1809329735, states[0] = -95.031704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822749309, states[0] = -94.932102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837616131, states[0] = -36.054478, states[40]= 0.000229
Saving checkpoint... 
Iteration: 1850605694, states[0] = -25.472139, states[40]= 0.000687
Saving checkpoint... 
Iteration: 1864126538, states[0] = -45.880879, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1878618586, states[0] = -37.418015, states[40]= 0.000190
Saving checkpoint... 
Iteration: 1892354970, states[0] = -94.989933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905936998, states[0] = -95.017662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919233237, states[0] = -94.865024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932099048, states[0] = -18.268936, states[40]= 0.001107
Saving checkpoint... 
Iteration: 1945349337, states[0] = -94.982627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959122742, states[0] = -41.204964, states[40]= 0.000110
Saving checkpoint... 
Iteration: 1971855533, states[0] = -94.985297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984205837, states[0] = -94.808991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997580895, states[0] = -2.846263, states[40]= 0.003829
Saving checkpoint... 
Iteration: 2011583444, states[0] = -4.602314, states[40]= 0.003494
Saving checkpoint... 
Iteration: 2025880376, states[0] = -94.996256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040068075, states[0] = 4.300396, states[40]= 0.004702
Saving checkpoint... 
Iteration: 2053509676, states[0] = 23.580834, states[40]= 0.058770
Saving checkpoint... 
Iteration: 2067107237, states[0] = -26.009185, states[40]= 0.000663
Saving checkpoint... 
Iteration: 2080999115, states[0] = -95.025294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094092097, states[0] = -11.676934, states[40]= 0.002017
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.901268
 - CaMKt in component CaMK (millimolar): 0.006974
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.462013
 - nass in component intracellular_ions (millimolar): 6.462075
 - ki in component intracellular_ions (millimolar): 145.515617
 - kss in component intracellular_ions (millimolar): 145.515596
 - cansr in component intracellular_ions (millimolar): 1.312846
 - cajsr in component intracellular_ions (millimolar): 1.274792
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003619
 - hf in component INa (dimensionless): 0.879991
 - hs in component INa (dimensionless): 0.879985
 - j in component INa (dimensionless): 0.879952
 - hsp in component INa (dimensionless): 0.725807
 - jp in component INa (dimensionless): 0.879930
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709662
 - hLp in component INaL (dimensionless): 0.451260
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620871
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695395
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934179
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001610
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339244
 - xs1 in component IKs (dimensionless): 0.243115
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:06:55 (5768): called boinc_finish(0)

</stderr_txt>
]]>


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