𝕏

Task 55402936

Name HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_383_1
Workunit 26308259
Created 30 Jun 2024, 6:02:20 UTC
Sent 30 Jun 2024, 7:47:21 UTC
Report deadline 3 Jul 2024, 17:23:21 UTC
Received 30 Jun 2024, 12:53:59 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237332
Run time 3 hours 25 min 12 sec
CPU time 3 hours 15 min 51 sec
Validate state Valid
Credit 61.12
Device peak FLOPS 4.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.97 MB
Peak swap size 32.63 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_383.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_383_1_r957309394_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_383_1_r957309394_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.636921
     * GNaL_b in INaL: 0.005618
     * Gto_b in Ito: 0.092585
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032916
     * GKs_b in IKs: 0.001827
     * GK1_b in IK1: 0.177773
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 69.660024
     * GKb_b in IKb: 0.003892
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039960
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14930033, states[0] = -95.121905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29895954, states[0] = -95.088546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44449698, states[0] = -95.087435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59074966, states[0] = -0.247001, states[40]= 0.004159
Saving checkpoint... 
Iteration: 74390237, states[0] = -95.061065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89161580, states[0] = -92.772697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104054421, states[0] = 9.544690, states[40]= 0.004735
Saving checkpoint... 
Iteration: 118928484, states[0] = -95.064357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133394032, states[0] = -95.055094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148344189, states[0] = -95.036243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163234454, states[0] = -94.943498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177884537, states[0] = -95.051132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192737420, states[0] = -94.947210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207671040, states[0] = -94.726710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222582094, states[0] = -4.259358, states[40]= 0.003495
Saving checkpoint... 
Iteration: 237223202, states[0] = -94.926205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252144838, states[0] = -66.527193, states[40]= 0.000002
Saving checkpoint... 
Iteration: 266767144, states[0] = -94.981755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281565931, states[0] = 4.748595, states[40]= 0.004593
Saving checkpoint... 
Iteration: 296468677, states[0] = -95.068971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311144922, states[0] = -66.637535, states[40]= 0.000002
Saving checkpoint... 
Iteration: 325878058, states[0] = -95.048531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340498359, states[0] = -95.072633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354874132, states[0] = -95.047169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369665606, states[0] = -94.176636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384738163, states[0] = -94.947811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399683894, states[0] = -94.852245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415210315, states[0] = -94.904553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430219399, states[0] = -94.919921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444485299, states[0] = -95.071048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459230880, states[0] = -94.937551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474128476, states[0] = -47.449099, states[40]= 0.000043
Saving checkpoint... 
Iteration: 488876569, states[0] = -95.047899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504284049, states[0] = -94.997072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518937614, states[0] = -95.063626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534217528, states[0] = -94.916776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548845156, states[0] = -95.035438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563395479, states[0] = -95.053713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578354159, states[0] = -95.039363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593236123, states[0] = -94.944867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607937124, states[0] = -95.063464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622935762, states[0] = -95.063189, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_383.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_383_1_r957309394_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_383_1_r957309394_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.636921
     * GNaL_b in INaL: 0.005618
     * Gto_b in Ito: 0.092585
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032916
     * GKs_b in IKs: 0.001827
     * GK1_b in IK1: 0.177773
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 69.660024
     * GKb_b in IKb: 0.003892
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.039960
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 622935762
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.063189 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 637799021, states[0] = -95.008649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652570958, states[0] = 2.326694, states[40]= 0.004426
Saving checkpoint... 
Iteration: 667230039, states[0] = -94.936164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682167200, states[0] = -94.444785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697231229, states[0] = -94.937873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712223239, states[0] = -94.925827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727159974, states[0] = -91.066920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741929890, states[0] = -95.061922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756545699, states[0] = 12.925157, states[40]= 0.004801
Saving checkpoint... 
Iteration: 771798123, states[0] = -95.007895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786702042, states[0] = -94.889185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801944151, states[0] = -95.064623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816485932, states[0] = -95.070840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831345785, states[0] = -95.035508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846265470, states[0] = -94.979590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861547100, states[0] = 12.409401, states[40]= 0.004785
Saving checkpoint... 
Iteration: 876417571, states[0] = -95.059134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892045240, states[0] = 13.092970, states[40]= 0.004808
Saving checkpoint... 
Iteration: 907333939, states[0] = -95.029736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922416392, states[0] = -95.058825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937500592, states[0] = 29.073352, states[40]= 0.001745
Saving checkpoint... 
Iteration: 952565855, states[0] = 4.784141, states[40]= 0.004595
Saving checkpoint... 
Iteration: 967638977, states[0] = -59.165116, states[40]= 0.000006
Saving checkpoint... 
Iteration: 982401023, states[0] = -95.054924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997712628, states[0] = -94.908137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012340728, states[0] = -95.033010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026695011, states[0] = -94.875423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041194788, states[0] = -94.874971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056051938, states[0] = 10.583550, states[40]= 0.004749
Saving checkpoint... 
Iteration: 1070823636, states[0] = -95.024074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085957896, states[0] = -95.066729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101045957, states[0] = 12.830673, states[40]= 0.004798
Saving checkpoint... 
Iteration: 1116115481, states[0] = -34.351377, states[40]= 0.000285
Saving checkpoint... 
Iteration: 1131046184, states[0] = 12.747321, states[40]= 0.004795
Saving checkpoint... 
Iteration: 1145805749, states[0] = -95.012957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160639272, states[0] = -59.513532, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1175582430, states[0] = -4.490118, states[40]= 0.003451
Saving checkpoint... 
Iteration: 1190310501, states[0] = -95.016056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205020468, states[0] = 20.377510, states[40]= 0.008318
Saving checkpoint... 
Iteration: 1219546279, states[0] = 12.712413, states[40]= 0.004794
Saving checkpoint... 
Iteration: 1234488451, states[0] = -95.070822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250315627, states[0] = -95.019227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265037604, states[0] = 15.781625, states[40]= 0.005010
Saving checkpoint... 
Iteration: 1280126594, states[0] = -45.456038, states[40]= 0.000058
Saving checkpoint... 
Iteration: 1295204078, states[0] = -94.892594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309887724, states[0] = -95.050858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325010461, states[0] = 21.698106, states[40]= 0.045457
Saving checkpoint... 
Iteration: 1340294088, states[0] = -95.004455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355321295, states[0] = -95.022517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370938601, states[0] = -95.063160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385230818, states[0] = -94.936746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399644660, states[0] = -66.279979, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1414215095, states[0] = -94.912030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428761851, states[0] = -94.975385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443253789, states[0] = -94.966483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457294311, states[0] = -95.004534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471626755, states[0] = -45.625011, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1486256471, states[0] = -94.969490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500804351, states[0] = -95.163800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515551520, states[0] = -95.251571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529566157, states[0] = -95.123559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1544110394, states[0] = 22.471649, states[40]= 0.047014
Saving checkpoint... 
Iteration: 1558465287, states[0] = -95.291735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572757073, states[0] = -95.115813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586495367, states[0] = -33.387569, states[40]= 0.000317
Saving checkpoint... 
Iteration: 1600712215, states[0] = -95.238232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614879192, states[0] = -95.311180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1629150046, states[0] = -95.069124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643121928, states[0] = 19.483932, states[40]= 0.008659
Saving checkpoint... 
Iteration: 1656916811, states[0] = 20.870295, states[40]= 0.013994
Saving checkpoint... 
Iteration: 1671805752, states[0] = -95.230248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686462623, states[0] = -95.139598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700449663, states[0] = 7.273727, states[40]= 0.005412
Saving checkpoint... 
Iteration: 1715149754, states[0] = 7.224076, states[40]= 0.005408
Saving checkpoint... 
Iteration: 1729630613, states[0] = -81.599192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744075557, states[0] = -95.171467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758283505, states[0] = -95.315681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772250580, states[0] = -95.078383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786405850, states[0] = -95.230536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1800737601, states[0] = -95.012735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814973013, states[0] = -95.106791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829241752, states[0] = -94.977539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843360240, states[0] = -95.058009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857519022, states[0] = 20.506852, states[40]= 0.009468
Saving checkpoint... 
Iteration: 1871976644, states[0] = -95.076078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886165520, states[0] = -94.240883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900678694, states[0] = -94.837876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914864998, states[0] = -95.044623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929441027, states[0] = -95.064433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943495516, states[0] = -95.071885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957816558, states[0] = -95.019747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972528153, states[0] = 18.655746, states[40]= 0.005785
Saving checkpoint... 
Iteration: 1987415744, states[0] = -95.058017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001491435, states[0] = -95.070663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015951250, states[0] = -95.064955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029693068, states[0] = -94.870766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043808396, states[0] = -95.013999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058890743, states[0] = -95.051144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072838875, states[0] = -95.031244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086893741, states[0] = -95.051983, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.947265
 - CaMKt in component CaMK (millimolar): 0.007260
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.628639
 - nass in component intracellular_ions (millimolar): 6.628699
 - ki in component intracellular_ions (millimolar): 145.344024
 - kss in component intracellular_ions (millimolar): 145.344005
 - cansr in component intracellular_ions (millimolar): 1.328003
 - cajsr in component intracellular_ions (millimolar): 1.289708
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003602
 - hf in component INa (dimensionless): 0.880787
 - hs in component INa (dimensionless): 0.880782
 - j in component INa (dimensionless): 0.880756
 - hsp in component INa (dimensionless): 0.727315
 - jp in component INa (dimensionless): 0.880738
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711457
 - hLp in component INaL (dimensionless): 0.454419
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.622308
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.697867
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937119
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001655
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.313673
 - xs1 in component IKs (dimensionless): 0.239969
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997325
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:21:05 (27577): called boinc_finish(0)

</stderr_txt>
]]>


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