𝕏

Task 55402598

Name HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_954_1
Workunit 26308090
Created 30 Jun 2024, 6:02:05 UTC
Sent 30 Jun 2024, 7:52:11 UTC
Report deadline 3 Jul 2024, 17:28:11 UTC
Received 30 Jun 2024, 16:21:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 2 hours 19 min 11 sec
CPU time 2 hours 9 min 36 sec
Validate state Valid
Credit 61.50
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.11 MB
Peak swap size 4.13 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_954.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_954_1_r2102336222_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_954_1_r2102336222_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 112.854157
     * GNaL_b in INaL: 0.005854
     * Gto_b in Ito: 0.086292
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029909
     * GKs_b in IKs: 0.002025
     * GK1_b in IK1: 0.147138
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 74.258628
     * GKb_b in IKb: 0.003752
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038462
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13860824, states[0] = -94.883951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26031803, states[0] = 17.539426, states[40]= 0.005907
Saving checkpoint... 
Iteration: 38861409, states[0] = -94.814537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50263099, states[0] = -94.721261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63551458, states[0] = 11.099232, states[40]= 0.004954
Saving checkpoint... 
Iteration: 75700937, states[0] = -94.595557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88186837, states[0] = -94.529363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100923885, states[0] = -94.793979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113456050, states[0] = -94.798849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126489235, states[0] = -94.802632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138972795, states[0] = -94.799099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151894590, states[0] = -94.779443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164270119, states[0] = -94.695530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176104536, states[0] = -21.171391, states[40]= 0.000904
Saving checkpoint... 
Iteration: 188809838, states[0] = -94.733318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201658093, states[0] = -74.995802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213183113, states[0] = -94.433210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226075783, states[0] = 0.861835, states[40]= 0.004313
Saving checkpoint... 
Iteration: 238185033, states[0] = -94.482315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251622556, states[0] = -37.461618, states[40]= 0.000187
Saving checkpoint... 
Iteration: 263929237, states[0] = -94.787979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276673314, states[0] = -92.950390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289881600, states[0] = -94.773073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302784624, states[0] = -94.710211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315969193, states[0] = -94.796095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328795584, states[0] = -94.720694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341265561, states[0] = -94.688847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354313675, states[0] = -94.735655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366362756, states[0] = -94.764983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378588442, states[0] = -7.166905, states[40]= 0.002897
Saving checkpoint... 
Iteration: 391784905, states[0] = -94.710426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404688052, states[0] = -94.525064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417302031, states[0] = -94.726289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430071768, states[0] = 2.892352, states[40]= 0.004522
Saving checkpoint... 
Iteration: 442587587, states[0] = -6.522640, states[40]= 0.003035
Saving checkpoint... 
Iteration: 455850841, states[0] = -94.759047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468893573, states[0] = -94.777333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481155998, states[0] = -72.133497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 493848272, states[0] = -94.757664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506116634, states[0] = -32.047407, states[40]= 0.000381
Saving checkpoint... 
Iteration: 518848732, states[0] = -94.757895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531522696, states[0] = 20.709107, states[40]= 0.008173
Saving checkpoint... 
Iteration: 543666515, states[0] = -87.288151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556348493, states[0] = -94.757745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568882942, states[0] = -94.773398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581340192, states[0] = -94.753105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594084305, states[0] = -4.197897, states[40]= 0.003511
Saving checkpoint... 
Iteration: 606426482, states[0] = -94.787031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619132635, states[0] = -47.077770, states[40]= 0.000044
Saving checkpoint... 
Iteration: 632222187, states[0] = -94.622073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644313300, states[0] = -94.735193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657387882, states[0] = -94.775194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670181570, states[0] = -94.370042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682750792, states[0] = -94.669017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695810174, states[0] = -94.732756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708090714, states[0] = -8.953004, states[40]= 0.002518
Saving checkpoint... 
Iteration: 721291881, states[0] = -94.717030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734081050, states[0] = -2.114713, states[40]= 0.003889
Saving checkpoint... 
Iteration: 746352773, states[0] = -94.759872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759038470, states[0] = 16.124676, states[40]= 0.005353
Saving checkpoint... 
Iteration: 771949746, states[0] = -94.792213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784877429, states[0] = -94.771098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796236090, states[0] = -94.646349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809044172, states[0] = 14.114643, states[40]= 0.005105
Saving checkpoint... 
Iteration: 820821513, states[0] = -94.741061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833942884, states[0] = -94.790738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845843655, states[0] = -94.754921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857611156, states[0] = -27.099475, states[40]= 0.000623
Saving checkpoint... 
Iteration: 870395512, states[0] = -94.777756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883229665, states[0] = -94.635396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895409789, states[0] = -94.782278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908569445, states[0] = 3.991903, states[40]= 0.004611
Saving checkpoint... 
Iteration: 921021636, states[0] = 20.939047, states[40]= 0.008761
Saving checkpoint... 
Iteration: 934387007, states[0] = -94.774706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947926393, states[0] = -94.786803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959607318, states[0] = -23.643688, states[40]= 0.000784
Saving checkpoint... 
Iteration: 972130573, states[0] = -45.056153, states[40]= 0.000060
Saving checkpoint... 
Iteration: 985001103, states[0] = 50.299177, states[40]= 0.030485
Saving checkpoint... 
Iteration: 997550522, states[0] = 11.771830, states[40]= 0.004963
Saving checkpoint... 
Iteration: 1009746489, states[0] = -94.662535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022849765, states[0] = -94.758140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035870749, states[0] = -94.768159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049015445, states[0] = 22.060233, states[40]= 0.017746
Saving checkpoint... 
Iteration: 1062201351, states[0] = -94.579768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074474450, states[0] = -94.796490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087254768, states[0] = -94.674344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099770907, states[0] = -94.694790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112789140, states[0] = -94.714178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125189317, states[0] = -94.535565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138663037, states[0] = -82.286179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150768561, states[0] = -94.691991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163655506, states[0] = -71.494978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1176797159, states[0] = -94.721590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189982721, states[0] = -94.797690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202796096, states[0] = -94.720622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215424996, states[0] = -94.786286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228128792, states[0] = -43.331343, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1240732368, states[0] = -94.639842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253663335, states[0] = -82.738254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267094863, states[0] = -12.451911, states[40]= 0.001841
Saving checkpoint... 
Iteration: 1279951868, states[0] = -94.792334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293138754, states[0] = -53.186617, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1305322482, states[0] = -94.741442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317684350, states[0] = -94.466396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330121506, states[0] = -36.489329, states[40]= 0.000215
Saving checkpoint... 
Iteration: 1343271756, states[0] = -94.695629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356336408, states[0] = -94.750401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368989460, states[0] = -94.798544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381210271, states[0] = -94.598482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394242498, states[0] = -94.656232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406929774, states[0] = -94.787370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419472457, states[0] = -94.795961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433062753, states[0] = 6.936889, states[40]= 0.004784
Saving checkpoint... 
Iteration: 1445594770, states[0] = -12.370740, states[40]= 0.001855
Saving checkpoint... 
Iteration: 1458431578, states[0] = -94.787778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472132379, states[0] = -46.824934, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1485229973, states[0] = -94.635568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498746144, states[0] = -94.661723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511188824, states[0] = -20.734333, states[40]= 0.000969
Saving checkpoint... 
Iteration: 1524583089, states[0] = -95.068053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535784030, states[0] = -17.129450, states[40]= 0.001333
Saving checkpoint... 
Iteration: 1548562384, states[0] = -95.068554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560120298, states[0] = -56.674258, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1573847075, states[0] = 9.577171, states[40]= 0.005708
Saving checkpoint... 
Iteration: 1586760083, states[0] = 2.413379, states[40]= 0.005071
Saving checkpoint... 
Iteration: 1599366355, states[0] = -1.744344, states[40]= 0.004461
Saving checkpoint... 
Iteration: 1612530305, states[0] = 17.267863, states[40]= 0.007132
Saving checkpoint... 
Iteration: 1624979745, states[0] = -94.944262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637728140, states[0] = 18.124658, states[40]= 0.007546
Saving checkpoint... 
Iteration: 1650875327, states[0] = -95.098137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662954860, states[0] = 5.358010, states[40]= 0.005365
Saving checkpoint... 
Iteration: 1675787853, states[0] = -95.109119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688962901, states[0] = -95.086425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702042525, states[0] = -88.310311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714323558, states[0] = -61.170382, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1726520010, states[0] = 20.973216, states[40]= 0.011405
Saving checkpoint... 
Iteration: 1739504827, states[0] = -40.022592, states[40]= 0.000131
Saving checkpoint... 
Iteration: 1752238080, states[0] = -95.056786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764957908, states[0] = 3.616347, states[40]= 0.005204
Saving checkpoint... 
Iteration: 1777303215, states[0] = -38.307850, states[40]= 0.000166
Saving checkpoint... 
Iteration: 1790563560, states[0] = -94.881698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1802508737, states[0] = 23.423204, states[40]= 0.073647
Saving checkpoint... 
Iteration: 1815373869, states[0] = -94.818444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827473832, states[0] = -94.831300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840153235, states[0] = -70.589019, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1852705845, states[0] = -94.605895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865564898, states[0] = 5.823506, states[40]= 0.004737
Saving checkpoint... 
Iteration: 1878044837, states[0] = 13.776578, states[40]= 0.005087
Saving checkpoint... 
Iteration: 1890777858, states[0] = -94.707397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903618819, states[0] = -34.209137, states[40]= 0.000292
Saving checkpoint... 
Iteration: 1915898195, states[0] = -94.780434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928579059, states[0] = -0.980050, states[40]= 0.004069
Saving checkpoint... 
Iteration: 1940569474, states[0] = 3.955797, states[40]= 0.004609
Saving checkpoint... 
Iteration: 1952108197, states[0] = -24.473529, states[40]= 0.000747
Saving checkpoint... 
Iteration: 1965255981, states[0] = -94.675986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978664852, states[0] = -85.028592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991389283, states[0] = -94.775105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004784279, states[0] = -94.708939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017116230, states[0] = -31.686246, states[40]= 0.000398
Saving checkpoint... 
Iteration: 2029880972, states[0] = -94.771788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2042824185, states[0] = -94.742171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055872699, states[0] = -94.768366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068716211, states[0] = -94.609823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081213926, states[0] = -94.605333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093272330, states[0] = -94.695801, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.675323
 - CaMKt in component CaMK (millimolar): 0.006899
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.510864
 - nass in component intracellular_ions (millimolar): 6.510923
 - ki in component intracellular_ions (millimolar): 145.469199
 - kss in component intracellular_ions (millimolar): 145.469180
 - cansr in component intracellular_ions (millimolar): 1.302736
 - cajsr in component intracellular_ions (millimolar): 1.264479
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003702
 - hf in component INa (dimensionless): 0.876014
 - hs in component INa (dimensionless): 0.876009
 - j in component INa (dimensionless): 0.875977
 - hsp in component INa (dimensionless): 0.718359
 - jp in component INa (dimensionless): 0.875955
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.702229
 - hLp in component INaL (dimensionless): 0.440318
 - a in component Ito (dimensionless): 0.000633
 - iF in component Ito (dimensionless): 0.999864
 - iS in component Ito (dimensionless): 0.614271
 - ap in component Ito (dimensionless): 0.000322
 - iFp in component Ito (dimensionless): 0.999864
 - iSp in component Ito (dimensionless): 0.687472
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933371
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999876
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001567
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.344475
 - xs1 in component IKs (dimensionless): 0.246667
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997396
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:13:01 (96646): called boinc_finish(0)

</stderr_txt>
]]>


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