𝕏

Task 55402492

Name HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_543_1
Workunit 26308037
Created 30 Jun 2024, 6:02:00 UTC
Sent 30 Jun 2024, 7:47:58 UTC
Report deadline 3 Jul 2024, 17:23:58 UTC
Received 30 Jun 2024, 10:37:50 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233967
Run time 2 hours 27 min 7 sec
CPU time 2 hours 24 min 47 sec
Validate state Valid
Credit 61.28
Device peak FLOPS 4.88 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_543.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_543_1_r2095072660_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_543_1_r2095072660_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 119.372873
     * GNaL_b in INaL: 0.004776
     * Gto_b in Ito: 0.080134
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031054
     * GKs_b in IKs: 0.002130
     * GK1_b in IK1: 0.152239
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 70.217963
     * GKb_b in IKb: 0.003758
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049584
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15024346, states[0] = 18.945088, states[40]= 0.007981
Saving checkpoint... 
Iteration: 29964796, states[0] = -95.024496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45088309, states[0] = -14.257489, states[40]= 0.001608
Saving checkpoint... 
Iteration: 60150898, states[0] = -83.648016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75144562, states[0] = -72.892945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90157358, states[0] = -90.935842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105141983, states[0] = -68.645016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 120140501, states[0] = -66.603823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 135296135, states[0] = -94.906759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150464753, states[0] = -94.970052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165495517, states[0] = -94.973568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180585906, states[0] = -10.366790, states[40]= 0.002299
Saving checkpoint... 
Iteration: 195611673, states[0] = -35.480914, states[40]= 0.000227
Saving checkpoint... 
Iteration: 210579209, states[0] = -4.840967, states[40]= 0.003482
Saving checkpoint... 
Iteration: 225332041, states[0] = -94.927840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239905901, states[0] = -94.956455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254567364, states[0] = 2.446146, states[40]= 0.004610
Saving checkpoint... 
Iteration: 269132298, states[0] = -56.938050, states[40]= 0.000008
Saving checkpoint... 
Iteration: 283657819, states[0] = -90.762113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298205848, states[0] = -94.789410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312917532, states[0] = -94.959257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327971035, states[0] = -94.969315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342891274, states[0] = -94.952088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357769119, states[0] = -94.879987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372680996, states[0] = -94.733494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387555070, states[0] = 8.241485, states[40]= 0.005010
Saving checkpoint... 
Iteration: 402319641, states[0] = -94.920397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417128847, states[0] = -53.206913, states[40]= 0.000015
Saving checkpoint... 
Iteration: 432109410, states[0] = -33.216420, states[40]= 0.000304
Saving checkpoint... 
Iteration: 447121787, states[0] = -45.724674, states[40]= 0.000050
Saving checkpoint... 
Iteration: 462177235, states[0] = -94.714580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477248551, states[0] = -94.856450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492187440, states[0] = -94.751577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507321517, states[0] = -94.921480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522476018, states[0] = -94.969903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537503985, states[0] = 33.593185, states[40]= 0.136538
Saving checkpoint... 
Iteration: 552497979, states[0] = -94.972610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567403396, states[0] = -94.955479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582180284, states[0] = -94.730613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596930204, states[0] = -94.961953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611797684, states[0] = -94.905209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626776928, states[0] = -94.887522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641566320, states[0] = 2.986495, states[40]= 0.004662
Saving checkpoint... 
Iteration: 656036509, states[0] = 15.756709, states[40]= 0.005771
Saving checkpoint... 
Iteration: 670526833, states[0] = 19.072350, states[40]= 0.007210
Saving checkpoint... 
Iteration: 685052853, states[0] = 9.196697, states[40]= 0.005060
Saving checkpoint... 
Iteration: 699565578, states[0] = 3.362335, states[40]= 0.004695
Saving checkpoint... 
Iteration: 714099986, states[0] = -23.943613, states[40]= 0.000728
Saving checkpoint... 
Iteration: 728579254, states[0] = -4.863793, states[40]= 0.003477
Saving checkpoint... 
Iteration: 743092633, states[0] = -16.716092, states[40]= 0.001266
Saving checkpoint... 
Iteration: 757886304, states[0] = -94.950293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772647074, states[0] = -75.138424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787497030, states[0] = -94.972376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802259964, states[0] = -94.869907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816855813, states[0] = -94.938862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831369378, states[0] = -94.944337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846045469, states[0] = 12.260593, states[40]= 0.005266
Saving checkpoint... 
Iteration: 860772503, states[0] = -94.883116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875484640, states[0] = -94.970850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890321635, states[0] = -94.921343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904953381, states[0] = -94.966215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919510535, states[0] = 23.438751, states[40]= 0.048722
Saving checkpoint... 
Iteration: 934061908, states[0] = 5.149438, states[40]= 0.004832
Saving checkpoint... 
Iteration: 948636793, states[0] = -61.925046, states[40]= 0.000003
Saving checkpoint... 
Iteration: 963155031, states[0] = -87.540139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977645003, states[0] = -72.146508, states[40]= 0.000001
Saving checkpoint... 
Iteration: 992394582, states[0] = -94.952730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007227148, states[0] = -94.825902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022007427, states[0] = 25.474399, states[40]= 0.095492
Saving checkpoint... 
Iteration: 1036740652, states[0] = -94.845729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051648057, states[0] = -76.630855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066443238, states[0] = -94.964308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081088436, states[0] = -12.670354, states[40]= 0.001858
Saving checkpoint... 
Iteration: 1095473184, states[0] = -94.969196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110110103, states[0] = -33.900618, states[40]= 0.000279
Saving checkpoint... 
Iteration: 1124519041, states[0] = 21.211353, states[40]= 0.011712
Saving checkpoint... 
Iteration: 1138910669, states[0] = -94.957095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153393718, states[0] = -94.952384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167964587, states[0] = -94.967889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182630114, states[0] = -54.568348, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1197076325, states[0] = -2.805447, states[40]= 0.003878
Saving checkpoint... 
Iteration: 1211339934, states[0] = -94.931248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225662953, states[0] = -93.671839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239921072, states[0] = -94.959575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254204494, states[0] = -94.786286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268642779, states[0] = -69.154115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1282979613, states[0] = -94.969976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297270490, states[0] = -94.880866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311637900, states[0] = -63.195967, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1325970953, states[0] = -94.968752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340989840, states[0] = -94.971240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356117171, states[0] = -40.967637, states[40]= 0.000104
Saving checkpoint... 
Iteration: 1370848895, states[0] = -94.935477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385941791, states[0] = -94.963860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401171826, states[0] = -94.639290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415682847, states[0] = -94.739095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430779733, states[0] = -94.889698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445807791, states[0] = -94.912106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460976175, states[0] = -94.969415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476182946, states[0] = -94.739360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491321329, states[0] = -94.920831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506075399, states[0] = -11.452178, states[40]= 0.002286
Saving checkpoint... 
Iteration: 1520776545, states[0] = -13.782045, states[40]= 0.001860
Saving checkpoint... 
Iteration: 1535656776, states[0] = -95.219188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550748277, states[0] = 7.551661, states[40]= 0.005726
Saving checkpoint... 
Iteration: 1565506902, states[0] = -49.884884, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1580676280, states[0] = -95.256146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595680603, states[0] = -95.261868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610669363, states[0] = -95.254382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626004415, states[0] = 33.159763, states[40]= 0.114945
Saving checkpoint... 
Iteration: 1641213855, states[0] = -95.191155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656595534, states[0] = -95.275542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672045101, states[0] = -94.758292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687445489, states[0] = -95.233465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702925397, states[0] = -74.932904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1718298929, states[0] = -95.166613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733570451, states[0] = -95.105625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748339969, states[0] = -95.227348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763534858, states[0] = -90.107720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1778122017, states[0] = 19.930479, states[40]= 0.010426
Saving checkpoint... 
Iteration: 1793069414, states[0] = -95.256711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808007571, states[0] = 25.037072, states[40]= 0.095769
Saving checkpoint... 
Iteration: 1822591007, states[0] = -17.236536, states[40]= 0.001221
Saving checkpoint... 
Iteration: 1837583438, states[0] = -9.309010, states[40]= 0.002536
Saving checkpoint... 
Iteration: 1852631048, states[0] = -56.732859, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1867588983, states[0] = -13.723287, states[40]= 0.001685
Saving checkpoint... 
Iteration: 1882581271, states[0] = -6.680314, states[40]= 0.003095
Saving checkpoint... 
Iteration: 1897477531, states[0] = -94.973799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912321282, states[0] = -94.923462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926954805, states[0] = -94.967765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941861539, states[0] = -94.941851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956384332, states[0] = -94.949772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970849574, states[0] = -94.935957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985454031, states[0] = -94.966048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999845518, states[0] = -94.933742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014329485, states[0] = -94.925389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028887433, states[0] = -94.950022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043466921, states[0] = -94.967792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057759780, states[0] = -94.869016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071917574, states[0] = -94.958285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086182924, states[0] = -94.738936, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.847839
 - CaMKt in component CaMK (millimolar): 0.006611
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.549040
 - nass in component intracellular_ions (millimolar): 6.549098
 - ki in component intracellular_ions (millimolar): 145.433342
 - kss in component intracellular_ions (millimolar): 145.433323
 - cansr in component intracellular_ions (millimolar): 1.294295
 - cajsr in component intracellular_ions (millimolar): 1.257282
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003638
 - hf in component INa (dimensionless): 0.879060
 - hs in component INa (dimensionless): 0.879056
 - j in component INa (dimensionless): 0.879029
 - hsp in component INa (dimensionless): 0.724062
 - jp in component INa (dimensionless): 0.879010
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709484
 - hLp in component INaL (dimensionless): 0.453309
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.626083
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.701783
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939147
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999898
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001544
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335482
 - xs1 in component IKs (dimensionless): 0.231613
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997351
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:37:37 (597540): called boinc_finish(0)

</stderr_txt>
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