𝕏

Task 55400803

Name HuVeMOp_20240630080046859196_ORdGradInc_k_25-Drouin_ENDO_3000-conf_405_0
Workunit 26307194
Created 30 Jun 2024, 6:00:57 UTC
Sent 30 Jun 2024, 7:32:21 UTC
Report deadline 3 Jul 2024, 7:32:21 UTC
Received 2 Jul 2024, 5:09:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213681
Run time 2 hours 10 min 13 sec
CPU time 1 hours 58 min 13 sec
Validate state Valid
Credit 47.94
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.07 MB
Peak swap size 6.21 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Drouin_ENDO_3000-conf_405.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Drouin_ENDO_3000-conf_405_0_r847553998_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Drouin_ENDO_3000-conf_405_0_r847553998_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.739239
     * GNaL_b in INaL: 0.005300
     * Gto_b in Ito: 0.077752
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033315
     * GKs_b in IKs: 0.002036
     * GK1_b in IK1: 0.180776
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.672943
     * GKb_b in IKb: 0.003903
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045373
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12564854, states[0] = -94.372466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24737095, states[0] = -94.322599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37267264, states[0] = -94.284276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49042992, states[0] = -94.282283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61810400, states[0] = -94.059856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74198327, states[0] = -94.281700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85379504, states[0] = -94.262535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98465354, states[0] = -94.275285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110145060, states[0] = -94.275942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122822547, states[0] = -94.261922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135488374, states[0] = -94.243604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148017148, states[0] = -94.271643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160972813, states[0] = -94.236396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172813096, states[0] = -94.058234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185508336, states[0] = -94.271494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198054404, states[0] = 22.143264, states[40]= 0.000400
Saving checkpoint... 
Iteration: 210897755, states[0] = -94.275037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223268051, states[0] = -94.262268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235776089, states[0] = -93.957688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248063752, states[0] = -94.263900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259934214, states[0] = -94.213960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272043876, states[0] = -94.259634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283969384, states[0] = -94.234025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296578434, states[0] = -94.268447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308948248, states[0] = -94.256685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321380131, states[0] = -94.165866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333608170, states[0] = -94.270259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346314995, states[0] = -94.260352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358634851, states[0] = -25.998954, states[40]= 0.001692
Saving checkpoint... 
Iteration: 371471579, states[0] = -94.272013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383569702, states[0] = -94.268473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396485306, states[0] = -94.240768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408944817, states[0] = -94.272806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420821094, states[0] = -94.276192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432791328, states[0] = -94.276601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445365864, states[0] = -94.258523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458096841, states[0] = -94.268455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471069609, states[0] = 16.249658, states[40]= 0.000932
Saving checkpoint... 
Iteration: 483790353, states[0] = -94.276447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496627124, states[0] = -19.401892, states[40]= 0.001392
Saving checkpoint... 
Iteration: 509081211, states[0] = -94.266040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521768205, states[0] = -94.261237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534032749, states[0] = 29.241373, states[40]= 0.000133
Saving checkpoint... 
Iteration: 545911627, states[0] = -94.256905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558911113, states[0] = -94.273417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571617206, states[0] = -10.522744, states[40]= 0.002150
Saving checkpoint... 
Iteration: 583831316, states[0] = -94.093627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596128673, states[0] = -94.271509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608156971, states[0] = -94.273591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620846740, states[0] = -94.258513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633478713, states[0] = -94.237186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646130925, states[0] = -94.265444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658142626, states[0] = -94.264995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670826978, states[0] = -94.085145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682773831, states[0] = -93.948759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695174923, states[0] = -94.274269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707221816, states[0] = -94.275640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720183150, states[0] = -69.737271, states[40]= 0.000008
Saving checkpoint... 
Iteration: 732635171, states[0] = -94.271629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745204692, states[0] = -94.262588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758561853, states[0] = -94.267543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769664895, states[0] = -51.778296, states[40]= 0.000135
Saving checkpoint... 
Iteration: 781718282, states[0] = -93.706063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794281599, states[0] = -94.275529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807125730, states[0] = -18.168089, states[40]= 0.001394
Saving checkpoint... 
Iteration: 819693286, states[0] = -94.274589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832315532, states[0] = -94.258763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844505644, states[0] = 31.536737, states[40]= 0.264418
Saving checkpoint... 
Iteration: 856196835, states[0] = -94.262493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869142868, states[0] = -94.271793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881873930, states[0] = -94.256879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894326795, states[0] = -94.084062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907116959, states[0] = -94.265093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919202591, states[0] = -94.262096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931524169, states[0] = 31.129706, states[40]= 0.000491
Saving checkpoint... 
Iteration: 943105931, states[0] = -94.265368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955500966, states[0] = 45.706883, states[40]= 0.291202
Saving checkpoint... 
Iteration: 967612939, states[0] = -6.895082, states[40]= 0.002708
Saving checkpoint... 
Iteration: 980410428, states[0] = -94.272078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993241661, states[0] = -93.823027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005452843, states[0] = -94.223041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018357597, states[0] = -94.256910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030229701, states[0] = -94.260837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040991050, states[0] = -94.253201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053185392, states[0] = -72.542369, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1064612644, states[0] = -94.264737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077237462, states[0] = -93.803874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089783723, states[0] = -94.274557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101268658, states[0] = -93.929754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114010960, states[0] = -94.268223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126269903, states[0] = -94.259230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138722651, states[0] = -93.731826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150543464, states[0] = 26.001147, states[40]= 0.000210
Saving checkpoint... 
Iteration: 1163675067, states[0] = -94.262239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176150346, states[0] = -39.012367, states[40]= 0.000732
Saving checkpoint... 
Iteration: 1188540781, states[0] = -94.255929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200762859, states[0] = -94.274314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213591065, states[0] = 6.746800, states[40]= 0.002386
Saving checkpoint... 
Iteration: 1226471154, states[0] = -94.269266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238081451, states[0] = -94.263724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250324858, states[0] = -94.273444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261610787, states[0] = -5.189117, states[40]= 0.002923
Saving checkpoint... 
Iteration: 1272816024, states[0] = -94.273534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284391780, states[0] = -94.175264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297510961, states[0] = 31.260043, states[40]= 0.041808
Saving checkpoint... 
Iteration: 1309743003, states[0] = -93.827894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322173528, states[0] = -94.272181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334996085, states[0] = -94.252123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347433890, states[0] = -94.210199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360031398, states[0] = -94.266696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372134958, states[0] = -94.262956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383247907, states[0] = -93.848763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395178930, states[0] = -65.016019, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1407150571, states[0] = -39.203516, states[40]= 0.000716
Saving checkpoint... 
Iteration: 1419913051, states[0] = -94.270577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432354001, states[0] = -94.255677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444208417, states[0] = -94.260204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456718271, states[0] = -93.703714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468857109, states[0] = -94.132744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480951596, states[0] = -94.220795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493388187, states[0] = -94.271093, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.127449
 - CaMKt in component CaMK (millimolar): 0.003050
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 6.632905
 - nass in component intracellular_ions (millimolar): 6.633025
 - ki in component intracellular_ions (millimolar): 145.221217
 - kss in component intracellular_ions (millimolar): 145.221205
 - cansr in component intracellular_ions (millimolar): 1.822291
 - cajsr in component intracellular_ions (millimolar): 1.821985
 - cai in component intracellular_ions (millimolar): 0.000103
 - m in component INa (dimensionless): 0.003913
 - hf in component INa (dimensionless): 0.865900
 - hs in component INa (dimensionless): 0.865901
 - j in component INa (dimensionless): 0.865907
 - hsp in component INa (dimensionless): 0.699828
 - jp in component INa (dimensionless): 0.865910
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708336
 - hLp in component INaL (dimensionless): 0.511696
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.969940
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.985045
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990573
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004931
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.028276
 - xs1 in component IKs (dimensionless): 0.070302
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997533
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:56:17 (15248): called boinc_finish(0)

</stderr_txt>
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