𝕏

Task 55400112

Name HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_493_1
Workunit 26307004
Created 30 Jun 2024, 4:50:40 UTC
Sent 30 Jun 2024, 7:24:30 UTC
Report deadline 3 Jul 2024, 17:00:30 UTC
Received 1 Jul 2024, 0:34:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235062
Run time 53 min 3 sec
CPU time 50 min 17 sec
Validate state Valid
Credit 59.70
Device peak FLOPS 5.41 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.24 MB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_493.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_493_1_r1734110835_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_493_1_r1734110835_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 109.208262
     * GNaL_b in INaL: 0.005414
     * Gto_b in Ito: 0.089052
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033054
     * GKs_b in IKs: 0.001917
     * GK1_b in IK1: 0.149638
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 74.235819
     * GKb_b in IKb: 0.003791
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020562
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 37722454, states[0] = -94.746038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81491371, states[0] = -94.888069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127986973, states[0] = -94.878262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171962423, states[0] = -94.872037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213697228, states[0] = -94.642993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260187838, states[0] = -94.619182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304563444, states[0] = 5.045288, states[40]= 0.004733
Saving checkpoint... 
Iteration: 344026261, states[0] = 19.077638, states[40]= 0.006628
Saving checkpoint... 
Iteration: 384203859, states[0] = -94.657729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428859999, states[0] = -94.839177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473646674, states[0] = -71.682172, states[40]= 0.000001
Saving checkpoint... 
Iteration: 520054578, states[0] = 8.941610, states[40]= 0.004889
Saving checkpoint... 
Iteration: 565847808, states[0] = -94.832784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611773257, states[0] = -94.772447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648200255, states[0] = -94.649441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690287965, states[0] = -94.788099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710577798, states[0] = -2.855394, states[40]= 0.003835
Saving checkpoint... 
Iteration: 724242835, states[0] = -94.731330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736436607, states[0] = -94.865472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747374390, states[0] = -94.845503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759955634, states[0] = -94.869563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773013571, states[0] = 21.660575, states[40]= 0.024079
Saving checkpoint... 
Iteration: 787011031, states[0] = 22.149433, states[40]= 0.041998
Saving checkpoint... 
Iteration: 800149303, states[0] = -75.377461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813573506, states[0] = -0.174852, states[40]= 0.004253
Saving checkpoint... 
Iteration: 826769582, states[0] = -94.767991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840114112, states[0] = -36.116373, states[40]= 0.000221
Saving checkpoint... 
Iteration: 853979408, states[0] = -94.873687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867503393, states[0] = 34.373434, states[40]= 0.153049
Saving checkpoint... 
Iteration: 880425221, states[0] = -94.862537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894011128, states[0] = 22.126313, states[40]= 0.041061
Saving checkpoint... 
Iteration: 907570451, states[0] = 1.539471, states[40]= 0.004457
Saving checkpoint... 
Iteration: 920799024, states[0] = -94.798298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935416076, states[0] = -94.859991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949102909, states[0] = -25.216668, states[40]= 0.000683
Saving checkpoint... 
Iteration: 963534570, states[0] = 16.542782, states[40]= 0.005512
Saving checkpoint... 
Iteration: 977675093, states[0] = -94.522361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992016139, states[0] = 21.247842, states[40]= 0.015184
Saving checkpoint... 
Iteration: 1005684844, states[0] = -94.609095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019760565, states[0] = -94.756577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033531624, states[0] = 17.504656, states[40]= 0.005781
Saving checkpoint... 
Iteration: 1047079790, states[0] = -4.232038, states[40]= 0.003577
Saving checkpoint... 
Iteration: 1061094459, states[0] = -17.021963, states[40]= 0.001229
Saving checkpoint... 
Iteration: 1074671433, states[0] = -94.389675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088416493, states[0] = -94.860005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101906319, states[0] = -94.856951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115636777, states[0] = -59.817153, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1128994646, states[0] = -94.875718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142957588, states[0] = -94.869680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156881925, states[0] = -94.848306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170369776, states[0] = -94.843209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182796796, states[0] = -94.796121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197421316, states[0] = -94.861274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211331082, states[0] = -94.822394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225233595, states[0] = -94.715801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239247386, states[0] = -94.737948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253328474, states[0] = -94.820663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267571020, states[0] = 1.230562, states[40]= 0.004424
Saving checkpoint... 
Iteration: 1281563562, states[0] = 4.990574, states[40]= 0.004730
Saving checkpoint... 
Iteration: 1295310360, states[0] = -94.807526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309403240, states[0] = -94.855828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323418188, states[0] = -94.860322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336668402, states[0] = -94.123930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350667805, states[0] = -94.040967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364580878, states[0] = -5.024009, states[40]= 0.003418
Saving checkpoint... 
Iteration: 1378094407, states[0] = -16.971441, states[40]= 0.001234
Saving checkpoint... 
Iteration: 1391883567, states[0] = -94.848787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406047284, states[0] = 11.876280, states[40]= 0.004992
Saving checkpoint... 
Iteration: 1420177668, states[0] = -94.563402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434777589, states[0] = -94.776749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449183532, states[0] = -94.603761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463309087, states[0] = -94.806397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476705156, states[0] = -94.659831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490817351, states[0] = -94.812730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504717594, states[0] = -95.032734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518808223, states[0] = -95.033470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531857544, states[0] = 2.638447, states[40]= 0.005133
Saving checkpoint... 
Iteration: 1544963442, states[0] = -95.139017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557926226, states[0] = 18.153105, states[40]= 0.007773
Saving checkpoint... 
Iteration: 1571842981, states[0] = -93.989569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585161406, states[0] = -95.151862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598643728, states[0] = -95.132876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612016315, states[0] = -60.734672, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1626350215, states[0] = 6.483239, states[40]= 0.005515
Saving checkpoint... 
Iteration: 1640338990, states[0] = -95.129092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653384713, states[0] = -24.023335, states[40]= 0.000758
Saving checkpoint... 
Iteration: 1664592428, states[0] = -95.046007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676106430, states[0] = 26.194961, states[40]= 0.112724
Saving checkpoint... 
Iteration: 1688140775, states[0] = 11.490795, states[40]= 0.005977
Saving checkpoint... 
Iteration: 1699463228, states[0] = -95.158954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711529166, states[0] = 16.852404, states[40]= 0.007131
Saving checkpoint... 
Iteration: 1723483515, states[0] = -95.178157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1734302519, states[0] = 41.491445, states[40]= 0.095559
Saving checkpoint... 
Iteration: 1746095342, states[0] = -35.948727, states[40]= 0.000225
Saving checkpoint... 
Iteration: 1757962259, states[0] = -95.157978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768983844, states[0] = -95.025786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780799760, states[0] = -95.190771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792984097, states[0] = -95.026401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805066619, states[0] = 1.983063, states[40]= 0.004615
Saving checkpoint... 
Iteration: 1818548207, states[0] = 10.855639, states[40]= 0.004987
Saving checkpoint... 
Iteration: 1832241588, states[0] = -94.760658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845826219, states[0] = -94.839847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859270375, states[0] = -94.782335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872458640, states[0] = -94.878672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885996610, states[0] = -94.881594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900244991, states[0] = -94.737899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914711127, states[0] = -94.674972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928129499, states[0] = -52.045596, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1941502350, states[0] = 41.899751, states[40]= 0.111626
Saving checkpoint... 
Iteration: 1954778807, states[0] = -94.778441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968517043, states[0] = 21.093806, states[40]= 0.013284
Saving checkpoint... 
Iteration: 1980713721, states[0] = -94.678030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993633597, states[0] = -56.359692, states[40]= 0.000009
Saving checkpoint... 
Iteration: 2007106513, states[0] = -28.715637, states[40]= 0.000518
Saving checkpoint... 
Iteration: 2019804123, states[0] = -94.801987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032570421, states[0] = 1.554400, states[40]= 0.004458
Saving checkpoint... 
Iteration: 2046716431, states[0] = -94.683193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060417771, states[0] = -94.859669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2074167400, states[0] = -93.976139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088202291, states[0] = -94.652994, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.751579
 - CaMKt in component CaMK (millimolar): 0.007073
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.522554
 - nass in component intracellular_ions (millimolar): 6.522615
 - ki in component intracellular_ions (millimolar): 145.452215
 - kss in component intracellular_ions (millimolar): 145.452195
 - cansr in component intracellular_ions (millimolar): 1.322681
 - cajsr in component intracellular_ions (millimolar): 1.284916
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003674
 - hf in component INa (dimensionless): 0.877369
 - hs in component INa (dimensionless): 0.877364
 - j in component INa (dimensionless): 0.877331
 - hsp in component INa (dimensionless): 0.720886
 - jp in component INa (dimensionless): 0.877309
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.706376
 - hLp in component INaL (dimensionless): 0.448822
 - a in component Ito (dimensionless): 0.000630
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.623410
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.698676
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938711
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999897
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001646
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328637
 - xs1 in component IKs (dimensionless): 0.234697
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997376
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:34:22 (15112): called boinc_finish(0)

</stderr_txt>
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