𝕏

Task 55399935

Name HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_190_0
Workunit 26306916
Created 30 Jun 2024, 4:50:33 UTC
Sent 30 Jun 2024, 7:23:11 UTC
Report deadline 3 Jul 2024, 16:59:11 UTC
Received 30 Jun 2024, 20:55:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235804
Run time 1 hours 12 min 44 sec
CPU time 1 hours 11 min 2 sec
Validate state Valid
Credit 59.27
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.22 MB
Peak swap size 5.27 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_190.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_190_0_r184856236_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_190_0_r184856236_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 109.274616
     * GNaL_b in INaL: 0.005844
     * Gto_b in Ito: 0.094451
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032371
     * GKs_b in IKs: 0.001798
     * GK1_b in IK1: 0.173123
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 65.731608
     * GKb_b in IKb: 0.003887
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019211
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9984879, states[0] = -95.119556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28960350, states[0] = -95.088686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47618612, states[0] = -37.879091, states[40]= 0.000182
Saving checkpoint... 
Iteration: 60842446, states[0] = -95.036964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74547844, states[0] = 11.888855, states[40]= 0.004865
Saving checkpoint... 
Iteration: 94703884, states[0] = -94.878955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114435421, states[0] = -95.061678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128656719, states[0] = -84.951234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141920717, states[0] = -95.057257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161275312, states[0] = -94.979866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180376238, states[0] = -95.043107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199710566, states[0] = -94.888623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213254797, states[0] = -94.956757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232220531, states[0] = -94.906490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251801090, states[0] = -95.001927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271421912, states[0] = -95.056647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291080703, states[0] = -3.350149, states[40]= 0.003700
Saving checkpoint... 
Iteration: 310869624, states[0] = -95.040205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330681909, states[0] = -94.824644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350247249, states[0] = -94.946926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369753988, states[0] = -94.955538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389369337, states[0] = -95.040027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408754897, states[0] = -94.956627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428571054, states[0] = 2.198925, states[40]= 0.004463
Saving checkpoint... 
Iteration: 448419959, states[0] = -95.056016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468456204, states[0] = -95.063657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487755855, states[0] = -94.957736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507460106, states[0] = -95.064310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526996273, states[0] = -95.069568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546622086, states[0] = -40.377170, states[40]= 0.000127
Saving checkpoint... 
Iteration: 566218931, states[0] = -94.903398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585937834, states[0] = -95.060008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605550356, states[0] = 11.059052, states[40]= 0.004838
Saving checkpoint... 
Iteration: 624932353, states[0] = -95.058794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644488569, states[0] = -95.068502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663859387, states[0] = -95.035679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683281311, states[0] = -94.984787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702925105, states[0] = -95.057075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722071597, states[0] = 1.922777, states[40]= 0.004437
Saving checkpoint... 
Iteration: 741550313, states[0] = 11.075301, states[40]= 0.004838
Saving checkpoint... 
Iteration: 764678127, states[0] = -94.805194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783795472, states[0] = -94.997063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803041278, states[0] = 14.358002, states[40]= 0.004995
Saving checkpoint... 
Iteration: 816205938, states[0] = -94.879110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835237370, states[0] = -94.932795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854085347, states[0] = -6.658667, states[40]= 0.003035
Saving checkpoint... 
Iteration: 873001246, states[0] = 49.300727, states[40]= 0.047129
Saving checkpoint... 
Iteration: 891770534, states[0] = -94.973973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910622958, states[0] = -41.244697, states[40]= 0.000112
Saving checkpoint... 
Iteration: 929275364, states[0] = -94.978867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948480413, states[0] = -95.067160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967405052, states[0] = -95.051662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986353652, states[0] = -95.032869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005284775, states[0] = -94.987733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024035119, states[0] = 16.420880, states[40]= 0.005275
Saving checkpoint... 
Iteration: 1042941607, states[0] = -95.060450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062155081, states[0] = -81.787257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075529462, states[0] = 18.108868, states[40]= 0.005795
Saving checkpoint... 
Iteration: 1094309190, states[0] = -95.007237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113212830, states[0] = -94.892007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132347483, states[0] = -95.029834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151725076, states[0] = -94.913415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170828508, states[0] = -95.019641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189923651, states[0] = -95.056367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209393833, states[0] = -95.048114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228810709, states[0] = -95.008205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247948671, states[0] = -95.061690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261952919, states[0] = -95.062475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281307299, states[0] = -95.005747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300006050, states[0] = 24.604594, states[40]= 0.135496
Saving checkpoint... 
Iteration: 1319187211, states[0] = -94.839041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338323367, states[0] = -95.016427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357110692, states[0] = -29.489424, states[40]= 0.000506
Saving checkpoint... 
Iteration: 1375899832, states[0] = -95.049834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394448476, states[0] = -95.061544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413439001, states[0] = -95.059638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432365157, states[0] = -95.037558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451993012, states[0] = -95.068476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470684411, states[0] = -94.831688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484201326, states[0] = -94.869421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503405822, states[0] = -41.037204, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1522042172, states[0] = -93.377442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540838434, states[0] = 13.056780, states[40]= 0.005985
Saving checkpoint... 
Iteration: 1559420570, states[0] = 19.858251, states[40]= 0.009970
Saving checkpoint... 
Iteration: 1572722029, states[0] = -65.133454, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1585789341, states[0] = -95.318042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604433559, states[0] = 14.978300, states[40]= 0.006343
Saving checkpoint... 
Iteration: 1617483834, states[0] = -95.181596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636491290, states[0] = -95.323098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1654725955, states[0] = -95.258126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667765496, states[0] = -2.818367, states[40]= 0.004288
Saving checkpoint... 
Iteration: 1686919710, states[0] = 19.993959, states[40]= 0.010660
Saving checkpoint... 
Iteration: 1708309809, states[0] = -49.906314, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1727032120, states[0] = -95.266872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746098552, states[0] = -36.891196, states[40]= 0.000208
Saving checkpoint... 
Iteration: 1759096660, states[0] = -95.209902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777650580, states[0] = -95.052551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796588502, states[0] = -95.193295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814334719, states[0] = -95.063764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833053907, states[0] = 9.188232, states[40]= 0.004813
Saving checkpoint... 
Iteration: 1851747241, states[0] = -94.960581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870349840, states[0] = -95.038819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889078139, states[0] = -1.900535, states[40]= 0.003954
Saving checkpoint... 
Iteration: 1907860215, states[0] = -95.037876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926845146, states[0] = -95.029652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945357438, states[0] = -95.034752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963786914, states[0] = -94.989425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982386534, states[0] = -95.045408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000900508, states[0] = -95.049692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019734204, states[0] = -94.927243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038413238, states[0] = -95.053107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055226363, states[0] = -94.914823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073599582, states[0] = -19.162903, states[40]= 0.001034
Saving checkpoint... 
Iteration: 2091597423, states[0] = -17.157445, states[40]= 0.001210
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.944666
 - CaMKt in component CaMK (millimolar): 0.007297
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.745890
 - nass in component intracellular_ions (millimolar): 6.745952
 - ki in component intracellular_ions (millimolar): 145.225850
 - kss in component intracellular_ions (millimolar): 145.225830
 - cansr in component intracellular_ions (millimolar): 1.333876
 - cajsr in component intracellular_ions (millimolar): 1.295613
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003603
 - hf in component INa (dimensionless): 0.880742
 - hs in component INa (dimensionless): 0.880737
 - j in component INa (dimensionless): 0.880708
 - hsp in component INa (dimensionless): 0.727227
 - jp in component INa (dimensionless): 0.880688
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711110
 - hLp in component INaL (dimensionless): 0.453526
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.621606
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.697006
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937328
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001682
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.323930
 - xs1 in component IKs (dimensionless): 0.239915
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997326
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:17:10 (33008): called boinc_finish(0)

</stderr_txt>
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