𝕏

Task 55399401

Name HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_157_0
Workunit 26306649
Created 30 Jun 2024, 4:50:10 UTC
Sent 30 Jun 2024, 7:13:46 UTC
Report deadline 3 Jul 2024, 16:49:46 UTC
Received 1 Jul 2024, 8:10:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232691
Run time 1 hours 30 min 48 sec
CPU time 1 hours 29 min 12 sec
Validate state Valid
Credit 60.43
Device peak FLOPS 4.35 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.93 MB
Peak swap size 6.39 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_157.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_157_0_r272770504_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_157_0_r272770504_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 108.396771
     * GNaL_b in INaL: 0.005582
     * Gto_b in Ito: 0.099904
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030185
     * GKs_b in IKs: 0.001791
     * GK1_b in IK1: 0.164219
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 73.915409
     * GKb_b in IKb: 0.003845
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030084
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10602350, states[0] = -23.136913, states[40]= 0.000773
Saving checkpoint... 
Iteration: 25272136, states[0] = -95.051350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39623031, states[0] = -38.799347, states[40]= 0.000166
Saving checkpoint... 
Iteration: 54366954, states[0] = -95.076688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69030874, states[0] = 18.076667, states[40]= 0.005413
Saving checkpoint... 
Iteration: 83694919, states[0] = -94.863778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98069984, states[0] = 4.208732, states[40]= 0.004540
Saving checkpoint... 
Iteration: 112167365, states[0] = -90.268633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126869016, states[0] = -95.054721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141475021, states[0] = -95.082506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155854404, states[0] = -95.046326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170498067, states[0] = -95.084719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180555157, states[0] = 10.337949, states[40]= 0.004712
Saving checkpoint... 
Iteration: 195207884, states[0] = -94.882151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205331577, states[0] = -95.032773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219870045, states[0] = -95.052417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234379216, states[0] = -95.056073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248769908, states[0] = -94.980102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262723599, states[0] = -94.912368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277120852, states[0] = -34.298339, states[40]= 0.000309
Saving checkpoint... 
Iteration: 291583436, states[0] = -2.667315, states[40]= 0.003756
Saving checkpoint... 
Iteration: 305797746, states[0] = -95.007716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319706030, states[0] = -94.877813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334305838, states[0] = -95.014379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348542906, states[0] = 14.631721, states[40]= 0.004810
Saving checkpoint... 
Iteration: 362925514, states[0] = -95.070484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377125510, states[0] = -38.605961, states[40]= 0.000172
Saving checkpoint... 
Iteration: 391721510, states[0] = -94.908383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405967216, states[0] = -95.079180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420484873, states[0] = -95.081957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434714132, states[0] = -94.894229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449229290, states[0] = -94.922256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463454996, states[0] = -95.076918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477917286, states[0] = -95.068233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492128678, states[0] = -41.616251, states[40]= 0.000111
Saving checkpoint... 
Iteration: 506519605, states[0] = 20.566057, states[40]= 0.009105
Saving checkpoint... 
Iteration: 520685552, states[0] = -94.812356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534728317, states[0] = -94.920504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548877949, states[0] = -95.055220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563775631, states[0] = -94.986144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579601549, states[0] = -16.956320, states[40]= 0.001221
Saving checkpoint... 
Iteration: 594709993, states[0] = -94.885799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604862407, states[0] = -95.048580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619275844, states[0] = -94.986331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633341694, states[0] = -95.038094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647673787, states[0] = -93.988696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657761217, states[0] = -94.969304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672259992, states[0] = -94.967750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686537431, states[0] = 16.387686, states[40]= 0.004981
Saving checkpoint... 
Iteration: 700987352, states[0] = -95.082097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715119101, states[0] = -32.700605, states[40]= 0.000376
Saving checkpoint... 
Iteration: 729018598, states[0] = 20.693903, states[40]= 0.010149
Saving checkpoint... 
Iteration: 743307114, states[0] = -95.015065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757722044, states[0] = -94.909086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772178061, states[0] = -94.598803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786741597, states[0] = -94.942005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801095411, states[0] = -11.560775, states[40]= 0.001988
Saving checkpoint... 
Iteration: 815522067, states[0] = 20.195034, states[40]= 0.007448
Saving checkpoint... 
Iteration: 830022624, states[0] = 20.099821, states[40]= 0.007192
Saving checkpoint... 
Iteration: 844398105, states[0] = -95.062227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858560319, states[0] = 8.396115, states[40]= 0.004689
Saving checkpoint... 
Iteration: 873049663, states[0] = 12.321513, states[40]= 0.004732
Saving checkpoint... 
Iteration: 887525751, states[0] = 19.493415, states[40]= 0.006209
Saving checkpoint... 
Iteration: 901868185, states[0] = -95.050919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916259140, states[0] = -94.966477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930455448, states[0] = -95.076646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944648051, states[0] = -61.739659, states[40]= 0.000004
Saving checkpoint... 
Iteration: 959095665, states[0] = -11.777526, states[40]= 0.001949
Saving checkpoint... 
Iteration: 969141594, states[0] = -54.693148, states[40]= 0.000014
Saving checkpoint... 
Iteration: 983662609, states[0] = -82.574750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998014515, states[0] = 21.081197, states[40]= 0.019145
Saving checkpoint... 
Iteration: 1012305473, states[0] = -95.013561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026734985, states[0] = -94.931369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041059617, states[0] = 8.668313, states[40]= 0.004693
Saving checkpoint... 
Iteration: 1055136349, states[0] = -49.242446, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1069527793, states[0] = 19.036964, states[40]= 0.005822
Saving checkpoint... 
Iteration: 1083781243, states[0] = -94.991629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098374843, states[0] = -95.053556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112600208, states[0] = -15.758680, states[40]= 0.001352
Saving checkpoint... 
Iteration: 1126757290, states[0] = -94.963927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140627224, states[0] = -40.224501, states[40]= 0.000136
Saving checkpoint... 
Iteration: 1155211608, states[0] = -94.888638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169428611, states[0] = -95.070633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183871937, states[0] = -95.052295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198394944, states[0] = -95.060909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213039860, states[0] = 15.625342, states[40]= 0.004889
Saving checkpoint... 
Iteration: 1227372918, states[0] = -95.052669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241806730, states[0] = -95.014380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256304467, states[0] = -95.012568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270794699, states[0] = -95.004294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285189328, states[0] = -94.834442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299518243, states[0] = 20.735756, states[40]= 0.010590
Saving checkpoint... 
Iteration: 1313790156, states[0] = -95.000131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328246108, states[0] = -94.948330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342466138, states[0] = -95.078275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356382475, states[0] = -95.056346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370975849, states[0] = -95.079860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385362373, states[0] = -95.047965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399860605, states[0] = -95.047139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414278334, states[0] = -94.988366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428533258, states[0] = 17.620209, states[40]= 0.005223
Saving checkpoint... 
Iteration: 1443104619, states[0] = -19.705427, states[40]= 0.001002
Saving checkpoint... 
Iteration: 1457478268, states[0] = -95.080172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471967370, states[0] = -95.078388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486135183, states[0] = -48.053914, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1500631867, states[0] = 17.283250, states[40]= 0.006523
Saving checkpoint... 
Iteration: 1514998345, states[0] = -95.314710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529023357, states[0] = -95.250001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543116775, states[0] = -95.250117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557412792, states[0] = -47.378227, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1571751440, states[0] = 7.581780, states[40]= 0.005397
Saving checkpoint... 
Iteration: 1585644069, states[0] = -91.939682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600079483, states[0] = -95.188860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614369364, states[0] = -3.472186, states[40]= 0.004108
Saving checkpoint... 
Iteration: 1628862941, states[0] = -95.138744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643174386, states[0] = -7.739394, states[40]= 0.003139
Saving checkpoint... 
Iteration: 1657634525, states[0] = -77.225176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671829843, states[0] = -95.289740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686343906, states[0] = 11.138890, states[40]= 0.005622
Saving checkpoint... 
Iteration: 1700628594, states[0] = -95.288053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714764806, states[0] = -95.331944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725035367, states[0] = 14.946512, states[40]= 0.006043
Saving checkpoint... 
Iteration: 1739205136, states[0] = -39.597621, states[40]= 0.000149
Saving checkpoint... 
Iteration: 1753565690, states[0] = -0.854758, states[40]= 0.004590
Saving checkpoint... 
Iteration: 1763452747, states[0] = 6.770305, states[40]= 0.005355
Saving checkpoint... 
Iteration: 1777763395, states[0] = -95.330540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791318313, states[0] = 20.671502, states[40]= 0.011966
Saving checkpoint... 
Iteration: 1804305853, states[0] = -95.069038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817647726, states[0] = -65.134511, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1831460877, states[0] = -95.105320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845884109, states[0] = -95.075017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860230491, states[0] = -94.935474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874313819, states[0] = -95.027117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888913898, states[0] = -95.071201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903301034, states[0] = -95.012509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913065076, states[0] = 6.433683, states[40]= 0.004641
Saving checkpoint... 
Iteration: 1927699521, states[0] = -94.863999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941830123, states[0] = -95.031237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956226678, states[0] = -94.917154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969881108, states[0] = -95.055736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984467630, states[0] = -95.078261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998659972, states[0] = -78.051797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013199577, states[0] = -94.862561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027589621, states[0] = -6.902390, states[40]= 0.002932
Saving checkpoint... 
Iteration: 2042164292, states[0] = -85.445100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056403660, states[0] = -95.063026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070582500, states[0] = -2.092939, states[40]= 0.003851
Saving checkpoint... 
Iteration: 2085141998, states[0] = -55.120507, states[40]= 0.000013
Saving checkpoint... 
Iteration: 2099440459, states[0] = -95.072613, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.958530
 - CaMKt in component CaMK (millimolar): 0.007436
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.474786
 - nass in component intracellular_ions (millimolar): 6.474848
 - ki in component intracellular_ions (millimolar): 145.496800
 - kss in component intracellular_ions (millimolar): 145.496780
 - cansr in component intracellular_ions (millimolar): 1.333442
 - cajsr in component intracellular_ions (millimolar): 1.294304
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003598
 - hf in component INa (dimensionless): 0.880981
 - hs in component INa (dimensionless): 0.880976
 - j in component INa (dimensionless): 0.880945
 - hsp in component INa (dimensionless): 0.727677
 - jp in component INa (dimensionless): 0.880924
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.709706
 - hLp in component INaL (dimensionless): 0.448711
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.615094
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.689177
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933483
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999876
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001677
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331164
 - xs1 in component IKs (dimensionless): 0.249467
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997322
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:23:37 (2764): called boinc_finish(0)

</stderr_txt>
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