𝕏

Task 55399110

Name HuVeMOp_20240630064831733006_ORdGradInc_k_25-Schmidt_575-conf_239_0
Workunit 26306504
Created 30 Jun 2024, 4:49:57 UTC
Sent 30 Jun 2024, 7:17:47 UTC
Report deadline 3 Jul 2024, 7:17:57 UTC
Received 30 Jun 2024, 12:03:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239941
Run time 2 hours 52 min 11 sec
CPU time 1 hours 38 min 37 sec
Validate state Valid
Credit 45.65
Device peak FLOPS 5.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 9.12 MB
Peak swap size 32.99 GB
Peak disk usage 0.21 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Schmidt_575-conf_239.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Schmidt_575-conf_239_0_r1173512181_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Schmidt_575-conf_239_0_r1173512181_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.934939
     * GNaL_b in INaL: 0.006560
     * Gto_b in Ito: 0.081924
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031873
     * GKs_b in IKs: 0.001792
     * GK1_b in IK1: 0.154009
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 72.791545
     * GKb_b in IKb: 0.003751
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049812
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 16461308, states[0] = 3.731949, states[40]= 0.000505
Saving checkpoint... 
Iteration: 33257856, states[0] = -84.398695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48388131, states[0] = -9.049487, states[40]= 0.000413
Saving checkpoint... 
Iteration: 64430405, states[0] = 27.426495, states[40]= 0.000049
Saving checkpoint... 
Iteration: 78335414, states[0] = -64.011594, states[40]= 0.000006
Saving checkpoint... 
Iteration: 95232665, states[0] = 5.995659, states[40]= 0.000193
Saving checkpoint... 
Iteration: 110965429, states[0] = -84.793614, states[40]= 0.000001
Saving checkpoint... 
Iteration: 126985656, states[0] = -84.425798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143249876, states[0] = 2.725438, states[40]= 0.000273
Saving checkpoint... 
Iteration: 159128908, states[0] = -71.880506, states[40]= 0.000002
Saving checkpoint... 
Iteration: 174902780, states[0] = -26.613751, states[40]= 0.000243
Saving checkpoint... 
Iteration: 190806670, states[0] = -84.394046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205155728, states[0] = -84.123876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221613733, states[0] = -84.659106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 237364942, states[0] = -84.245471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253153994, states[0] = -82.738262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269254773, states[0] = -82.960054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285318981, states[0] = -44.937482, states[40]= 0.000072
Saving checkpoint... 
Iteration: 300969675, states[0] = -84.681924, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Schmidt_575-conf_239.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Schmidt_575-conf_239_0_r1173512181_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Schmidt_575-conf_239_0_r1173512181_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.934939
     * GNaL_b in INaL: 0.006560
     * Gto_b in Ito: 0.081924
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031873
     * GKs_b in IKs: 0.001792
     * GK1_b in IK1: 0.154009
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 72.791545
     * GKb_b in IKb: 0.003751
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049812
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 300969675
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.681924 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 332408089, states[0] = 13.366291, states[40]= 0.000066
Saving checkpoint... 
Iteration: 353486684, states[0] = -80.300454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370134966, states[0] = -48.869920, states[40]= 0.000046
Saving checkpoint... 
Iteration: 387145140, states[0] = -84.152040, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Schmidt_575-conf_239.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Schmidt_575-conf_239_0_r1173512181_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Schmidt_575-conf_239_0_r1173512181_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.934939
     * GNaL_b in INaL: 0.006560
     * Gto_b in Ito: 0.081924
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031873
     * GKs_b in IKs: 0.001792
     * GK1_b in IK1: 0.154009
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 72.791545
     * GKb_b in IKb: 0.003751
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049812
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 387145140
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.152040 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 407709257, states[0] = 25.696796, states[40]= 0.000017
Saving checkpoint... 
Iteration: 423236974, states[0] = 24.429575, states[40]= 0.000011
Saving checkpoint... 
Iteration: 439929056, states[0] = 15.637593, states[40]= 0.000044
Saving checkpoint... 
Iteration: 456500998, states[0] = -84.651915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471316531, states[0] = -28.048758, states[40]= 0.000239
Saving checkpoint... 
Iteration: 487989633, states[0] = -25.856102, states[40]= 0.000244
Saving checkpoint... 
Iteration: 502577942, states[0] = 28.420689, states[40]= 0.000110


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Schmidt_575-conf_239.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Schmidt_575-conf_239_0_r1173512181_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Schmidt_575-conf_239_0_r1173512181_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.934939
     * GNaL_b in INaL: 0.006560
     * Gto_b in Ito: 0.081924
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031873
     * GKs_b in IKs: 0.001792
     * GK1_b in IK1: 0.154009
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 72.791545
     * GKb_b in IKb: 0.003751
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049812
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 502577942
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 28.420689 (After loading)
 - states[40]: 0.000110 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 528664681, states[0] = -84.655150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 546394446, states[0] = -75.657611, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562762325, states[0] = -51.544161, states[40]= 0.000033
Saving checkpoint... 
Iteration: 579045915, states[0] = 30.809119, states[40]= 0.001290
Saving checkpoint... 
Iteration: 593241966, states[0] = -56.903312, states[40]= 0.000017
Saving checkpoint... 
Iteration: 609633360, states[0] = -61.559505, states[40]= 0.000009
Saving checkpoint... 
Iteration: 625815617, states[0] = -84.530003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 639958545, states[0] = -84.762197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 656573014, states[0] = -84.497692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 672356119, states[0] = -84.269682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688353460, states[0] = 0.004780, states[40]= 0.000339
Saving checkpoint... 
Iteration: 704188913, states[0] = -25.011081, states[40]= 0.000244
Saving checkpoint... 
Iteration: 718783383, states[0] = 26.097364, states[40]= 0.000020
Saving checkpoint... 
Iteration: 735114807, states[0] = -84.741386, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750827845, states[0] = -84.039568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766648668, states[0] = -84.189575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782276029, states[0] = -84.772055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 798180765, states[0] = -1.911243, states[40]= 0.000378
Saving checkpoint... 
Iteration: 813789802, states[0] = -84.020833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829562723, states[0] = -51.986138, states[40]= 0.000032
Saving checkpoint... 
Iteration: 845337340, states[0] = -8.370487, states[40]= 0.000405
Saving checkpoint... 
Iteration: 859313003, states[0] = -84.732542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 874892778, states[0] = 27.461435, states[40]= 0.000050
Saving checkpoint... 
Iteration: 890364859, states[0] = -84.737482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 906381830, states[0] = -84.270010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921844872, states[0] = -45.913935, states[40]= 0.000065
Saving checkpoint... 
Iteration: 937323914, states[0] = 3.424814, states[40]= 0.000254
Saving checkpoint... 
Iteration: 951580417, states[0] = -84.657655, states[40]= 0.000001
Saving checkpoint... 
Iteration: 967192534, states[0] = 21.716627, states[40]= 0.000014
Saving checkpoint... 
Iteration: 978932941, states[0] = -84.784319, states[40]= 0.000001
Saving checkpoint... 
Iteration: 994435386, states[0] = -84.720641, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1009790008, states[0] = -11.403274, states[40]= 0.000366
Saving checkpoint... 
Iteration: 1023639871, states[0] = -69.814572, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1038916515, states[0] = -84.239594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054051488, states[0] = 1.544757, states[40]= 0.000302
Saving checkpoint... 
Iteration: 1069780564, states[0] = -84.776143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1085151332, states[0] = -53.244317, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1100537649, states[0] = -84.761408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1113422166, states[0] = -84.554498, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1129789027, states[0] = -84.424231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146555555, states[0] = 30.425008, states[40]= 0.301863
Saving checkpoint... 
Iteration: 1163108498, states[0] = -84.143622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179838880, states[0] = -84.575142, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1196312954, states[0] = 29.376844, states[40]= 0.000261
Saving checkpoint... 
Iteration: 1212646485, states[0] = -84.710322, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1228826214, states[0] = 17.198528, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1243494599, states[0] = 13.941610, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1259943687, states[0] = -44.565436, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1276433323, states[0] = -84.542768, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1292593348, states[0] = -84.771030, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1308558304, states[0] = -77.131869, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1324740560, states[0] = -84.579893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340964593, states[0] = 9.531494, states[40]= 0.000120
Saving checkpoint... 
Iteration: 1357249956, states[0] = -84.674675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368939028, states[0] = -81.687221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385122450, states[0] = -84.611522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1401306311, states[0] = 27.022937, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1417496228, states[0] = -47.422285, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1433451401, states[0] = -84.720310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1447830848, states[0] = -84.733331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1464181183, states[0] = -84.591656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1480704152, states[0] = -0.538229, states[40]= 0.000351
Saving checkpoint... 
Iteration: 1495161061, states[0] = -83.821580, states[40]= 0.000000
Total time: 3000350.000000
State Variables:
 - v in component membrane (millivolt): -84.657146
 - CaMKt in component CaMK (millimolar): 0.053861
 - cass in component intracellular_ions (millimolar): 0.000111
 - nai in component intracellular_ions (millimolar): 6.802708
 - nass in component intracellular_ions (millimolar): 6.802883
 - ki in component intracellular_ions (millimolar): 144.804315
 - kss in component intracellular_ions (millimolar): 144.804285
 - cansr in component intracellular_ions (millimolar): 2.200318
 - cajsr in component intracellular_ions (millimolar): 1.829699
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.010149
 - hf in component INa (dimensionless): 0.576667
 - hs in component INa (dimensionless): 0.576424
 - j in component INa (dimensionless): 0.575042
 - hsp in component INa (dimensionless): 0.328957
 - jp in component INa (dimensionless): 0.573478
 - mL in component INaL (dimensionless): 0.000347
 - hL in component INaL (dimensionless): 0.321066
 - hLp in component INaL (dimensionless): 0.136374
 - a in component Ito (dimensionless): 0.001244
 - iF in component Ito (dimensionless): 0.999216
 - iS in component Ito (dimensionless): 0.304242
 - ap in component Ito (dimensionless): 0.000634
 - iFp in component Ito (dimensionless): 0.999216
 - iSp in component Ito (dimensionless): 0.334550
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.811543
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990175
 - jca in component ICaL (dimensionless): 0.994202
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007637
 - xrf in component IKr (dimensionless): 0.002036
 - xrs in component IKr (dimensionless): 0.728721
 - xs1 in component IKs (dimensionless): 0.428109
 - xs2 in component IKs (dimensionless): 0.000287
 - xk1 in component IK1 (dimensionless): 0.996764
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
12:34:50 (4118): called boinc_finish(0)

</stderr_txt>
]]>